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Drug Development
Agilent Technologies
Companion Diagnostics
Precision Medicine
Oncology
Adcs (antibody Drug Conjugates)
Biotech
Next-Generation Sequencing
Immunohistochemistry
Women's Health Gap
Health Conditions Affecting Women
Sickle Cell Disease
Drug Approvals
Women's Health Research
Clinical Trials and Women's Inclusion
Medical AI
Radiology
Patient Psychosocial Health
CRISPR
Car-T Therapies

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

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Latest Episodes

The healthcare marketing landscape is evolving fast — shaped by regulatory shifts, patient empowerment, and the rise of digital health marketplaces. In this episode of The Top Line, sponsored by Havas Media Network, host Chris Hayden sits down with H... more

Welcome to the Fierce Biotech Graveyard, our annual ritual remembering the biotechs we lost in 2025 and those on the brink.

In this episode, Fierce Biotech’s Darren Incorvaia and Gabrielle Masson came together to chat about themes from this year’s ... more

Life sciences organizations are facing both intense pressure and extraordinary opportunity, according to Mark Sullivan, president of regulated industries at Salesforce. In a conversation with The Top Line’s Chris Hayden, Sullivan said companies too o... more

The FDA made waves in early September when it announced a plan to publicly release complete response letters (CRLs) at the same time they are issued to sponsoring companies, part of what the agency calls a push toward “radical transparency.”

At the... more

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Recent Guests

Mark Sullivan
President of Regulated Industries at Salesforce
Salesforce
Episode: Salesforce’s Mark Sullivan: AI and agentic systems will redefine life sciences (Sponsored)
Brian Hilberdink
President of Boehringer Ingelheim's U.S. Human Pharma
Boehringer Ingelheim
Episode: How Boehringer Ingelheim is buttressing its US business
Marie Flanagan
Regulatory and AI Governance Lead Safety Technologies at IQVIA, with 20 years of experience in pharmacovigilance and technology.
IQVIA
Episode: AI is changing drug safety, but governance sets the guardrails (Sponsored)
Dr. Freda Lewis-Hall
A psychiatrist and former chief medical officer of Pfizer
Pfizer
Episode: Rebuilding trust in pharma in the age of misinformation
Robert Abel
Chief Scientific Officer Platform at Schrödinger
Schrödinger
Episode: Schrödinger taps AI to speed drug discovery (Sponsored)
Glenn Pierce
Vice President of Medical at the World Federation of Hemophilia
World Federation of Hemophilia
Episode: Inside the commercial growing pains of hemophilia gene therapies
Dr. Scott Gottlieb
Former FDA Commissioner, Senior Fellow at the American Enterprise Institute, and influential voice in healthcare policy and regulation
American Enterprise Institute
Episode: Former FDA Chief Scott Gottlieb talks drug pricing, access and innovation (Sponsored)
Dr. Paul Offit
Director of the Vaccine Education Center and Attending Physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia
Children's Hospital of Philadelphia
Episode: Rebuilding trust: compassionate communication and public health (Sponsored)
Peter Pitts
A leading authority on healthcare policy, former FDA Associate Commissioner and current President of the Center for Medicine in the Public Interest.
Center for Medicine in the Public Interest
Episode: Peter Pitts talks FDA direction, industry communication (Sponsored)

Hosts

Ayla Ellison
Host of the show, dedicated to unpacking complex biopharma and medtech stories for audiences.
Ryan Kersman
Executive Vice President, Global Public Affairs and Health Policy at GCI Health, focusing on communication strategies in healthcare.

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Talking Points

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Salesforce’s Mark Sullivan: AI and agentic systems will redefine life sciences (Sponsored)
Q: What key message do you have for life science leaders evaluating technology partners?
Choose partners that are committed to transforming the industry and are not just focused on replacing existing applications.
Salesforce’s Mark Sullivan: AI and agentic systems will redefine life sciences (Sponsored)
Q: How should life science organizations be approaching their CRM systems?
Organizations should not only pivot to CRM solutions but also consider engaging across the entire enterprise, incorporating agentic capabilities.
Salesforce’s Mark Sullivan: AI and agentic systems will redefine life sciences (Sponsored)
Q: What is the most important transformation a life science company must undertake to not just survive, but also to thrive in this environment?
Companies must adopt new technologies, like AI, to genuinely transform the entire industry, rather than just focusing on survival.
How Boehringer Ingelheim is buttressing its US business
Q: How prepare are you for the rollouts of Zonkurtinib and Neurondomelast?
We are focusing on specialized sales resources for oncology and utilizing established strategies that worked for our existing products.
How Boehringer Ingelheim is buttressing its US business
Q: Could you talk specifically about how you plan to position Boehringer for growth in the US?
Focusing on treating underutilized conditions and ensuring clinical systems understand and use products like Jardiance more effectively.

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Frequently Asked Questions About The Top Line

What is The Top Line about and what kind of topics does it cover?

Focusing on the intersections of biopharma and medtech, this podcast provides listeners with insights into industry trends and developments. Weekly discussions feature journalists who analyze significant business news, including mergers, marketing strategies, drug research and development, as well as advancements in medical devices. The content is tailored for professionals in the healthcare and pharmaceutical sectors, offering not just news, but also critical analyses of how these trends impact the industry. Listeners can expect a blend of expert interviews, relevant updates, and a clear breakdown of complex topics to enhance understanding of the ongoing changes in the biopharma landscape.

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Which podcasts are similar to The Top Line?

These podcasts share a similar audience with The Top Line:

1. BioCentury This Week
2. The Readout Loud
3. Biotech Hangout
4. Economist Podcasts
5. Behind the Money

How many episodes of The Top Line are there?

The Top Line launched 2 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Top Line?

Recent guests on The Top Line include:

1. Mark Sullivan
2. Brian Hilberdink
3. Marie Flanagan
4. Dr. Freda Lewis-Hall
5. Robert Abel
6. Glenn Pierce
7. Dr. Scott Gottlieb
8. Dr. Paul Offit

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