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Artwork for The Top Line
FDA
Artificial Intelligence
Biopharma
Clinical Trials
Pharmaceutical Industry
Oncology
Mergers and Acquisitions
Drug Development
Eli Lilly
Drug Pricing
Biotechnology
Pfizer
Cell Therapy
Gene Therapy
Alzheimer's Disease
Lung Cancer
Novo Nordisk
Patient Engagement
Women In Life Sciences
Layoffs

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

PublishesTwice weeklyEpisodes100Founded3 years ago
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Latest Episodes

Recorded last week at Fierce Biotech Week in Boston, this episode of “The Top Line” features a conversation with Kristen Fortney, Ph.D., co-founder and CEO of BioAge Labs.

In a conversation with Ayla Ellison, editor-in-chief of Fierce Healthcare an... more

Despite a prolonged period of policy uncertainty in the U.S.—and the ripple effects across the global life sciences and healthcare industries—executives at health companies are still seeing opportunities amid the tumult. In many cases, they’re findin... more

After months of mixed messaging from the White House, the pharmaceutical industry has gained more clarity on the second Trump administration’s import tariff policy for drugs. While many of the industry’s biggest firms have navigated the trade threat ... more

In this sponsored episode of The Top Line, host Kelly Hogan speaks with Dr. Bettine Boltres, director of scientific affairs, integrated systems at West Pharmaceutical Services, about the development of the West Synchrony prefillable syringe system. A... more

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Recent Guests

Glenn Hunzinger
PwC's US health industry leader
PwC
Episode: Health execs persevere in new policy landscape
Christopher Young
Principal in KPMG's trade and customs practice
KPMG
Episode: Revisiting Pharma’s tariff reality
Bettina Boltres
Director of Scientific Affairs, Integrated Systems at West Pharmaceutical Services
West Pharmaceutical Services
Episode: Setting a new standard in prefillable syringe systems (Sponsored)
Mike Patterson
CEO of North America at Curium
Curium
Episode: Scaling theranostics through access, safety and trust (Sponsored)
Brett Monia
CEO of Ionis Pharmaceuticals
Ionis Pharmaceuticals
Episode: A pivotal time for an RNA pioneer
Manishaa O'Brien
Director of Commercial Operations
Marken UPS Healthcare Precision Logistics
Episode: Accelerating clinical trials with precision logistics (Sponsored)
Jeffrey Gerrish
Former Deputy U.S. Trade Representative
U.S. Government (former)
Episode: Can Trump’s deal with the UK become a model for similar drug price agreements?
Danielly Vicente
Associate Medical Director of Oncology and Hematology at Allucent
Allucent
Episode: Biomarkers are reshaping oncology trial design (Sponsored)
Dr. Dave Miller
Chief Scientific Officer at Austin Pharmaceuticals
Austin Pharmaceuticals
Episode: Fixing failed spray-dried formulations faster (Sponsored)

Hosts

Ayla Ellison
Host with insights into biopharma and medtech, bringing a journalistic perspective to industry trends.
Chris Hayden
Host and producer focused on pharmaceutical trends, providing analysis and news updates.
Irina Luo
Host connecting medical communications with strategic insights, focusing on the impact of AI and technology.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#54
United States/News/Business News
Apple Podcasts
#47
United Kingdom/News/Business News
Apple Podcasts
#241
Canada/News/Business News
Apple Podcasts
#24
Italy/News/Business News
Apple Podcasts
#41
Australia/News/Business News
Apple Podcasts
#107
France/News/Business News
Apple Podcasts
#131
Germany/News/Business News
Apple Podcasts
#238
Italy/News
Apple Podcasts
#19
Israel/News/Business News
Apple Podcasts
#19
Ireland/News/Business News
Apple Podcasts
#22
South Korea/News/Business News
Apple Podcasts
#32
South Africa/News/Business News
Apple Podcasts
#38
Denmark/News/Business News
Apple Podcasts
#39
Norway/News/Business News
Apple Podcasts
#55
China/News/Business News
Apple Podcasts
#56
Russia/News/Business News
Apple Podcasts
#61
Indonesia/News/Business News
Apple Podcasts
#71
Ukraine/News/Business News
Apple Podcasts
#91
Taiwan/News/Business News
Apple Podcasts
#95
Belgium/News/Business News
Apple Podcasts
#96
Japan/News/Business News
Apple Podcasts
#97
India/News/Business News
Apple Podcasts
#97
Netherlands/News/Business News
Apple Podcasts
#111
Singapore/News/Business News
Apple Podcasts
#134
Philippines/News/Business News
Apple Podcasts
#140
Poland/News/Business News
Apple Podcasts
#168
Spain/News/Business News
Apple Podcasts
#169
Finland/News/Business News
Apple Podcasts
#171
Hong Kong/News/Business News
Apple Podcasts
#189
Sweden/News/Business News
Apple Podcasts
#190
Saudi Arabia/News/Business News
Apple Podcasts
#191
Mexico/News/Business News
Apple Podcasts
#217
New Zealand/News/Business News
Apple Podcasts
#233
Austria/News/Business News
Apple Podcasts
#244
Switzerland/News/Business News
Apple Podcasts
#246
South Korea/News

Talking Points

Recent interactions between the hosts and their guests.

Setting a new standard in prefillable syringe systems (Sponsored)
Q: So starting off, could you tell us the story behind the West Synchrony Pre-Fillable Syringe System?
Bettina describes Synchrony as a market-leading, fully integrated system designed to replace fragmented components with a single-source solution that includes complete DV data, regulatory filings, and a unified specification, enabling faster, smoother development and approvals.
Accelerating clinical trials with precision logistics (Sponsored)
Q: What challenges do central labs face, and how does Marken mitigate them?
Labs require advanced notice for sample arrivals to prepare staff and resources; Marken mitigates delays by proactive planning, barcoded data integration, and regulatory expertise across borders.
Accelerating clinical trials with precision logistics (Sponsored)
Q: What trends do you see impacting Laboratory Advantage's supply chains going forward?
Increasing complexity of drugs and trials, alongside digital technologies like AI, RFID and IoT, will enhance visibility, decision-making, and cross-functional collaboration across the network.
Accelerating clinical trials with precision logistics (Sponsored)
Q: How does Laboratory Advantage accelerate clinical trials for central labs, and what performance metrics are tracked?
Central labs see improved accuracy and supply chain integrity, with on-time performance around 99.5% within defined windows, supported by real-time tracking and standardized documentation.
Accelerating clinical trials with precision logistics (Sponsored)
Q: Could you provide an overview of the Laboratory Advantage service line inside Marken Precision Logistics, and what differentiates it from competitors?
Laboratory Advantage accelerates clinical trials by ensuring sample stability, end-to-end visibility, and rapid, compliant shipping through Marken's global network, backed by dedicated Alliance Managers and integrated data systems.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About The Top Line

What is The Top Line about and what kind of topics does it cover?

Focused on the biopharma and medtech sectors, this series offers listeners insights into key trends and developments within these dynamic industries. Episodes dive into topics such as regulatory issues, drug development, clinical trials, patient access, and industry challenges like tariff impacts and manufacturing capacity. The hosts leverage their journalistic backgrounds to analyze significant business news, mergers, acquisitions, and innovations, ensuring listeners stay informed about what shapes healthcare and pharmaceutical markets. Unique for its blend of rigorous analysis and accessibility, the series caters to professionals seeking a deeper understanding of these crucial fields.

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Which podcasts are similar to The Top Line?

These podcasts share a similar audience with The Top Line:

1. BioCentury This Week
2. The Readout Loud
3. Biotech Hangout
4. The Long Run with Luke Timmerman
5. HBR IdeaCast

How many episodes of The Top Line are there?

The Top Line launched 3 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Top Line?

Recent guests on The Top Line include:

1. Glenn Hunzinger
2. Christopher Young
3. Bettina Boltres
4. Mike Patterson
5. Brett Monia
6. Manishaa O'Brien
7. Jeffrey Gerrish
8. Danielly Vicente

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