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Drug Development
Companion Diagnostics
Agilent Technologies
Precision Medicine
Adcs (antibody Drug Conjugates)
Oncology
Biotech
Next-Generation Sequencing
Immunohistochemistry
Women's Health Gap
Health Conditions Affecting Women
Sickle Cell Disease
Drug Approvals
Women's Health Research
Clinical Trials and Women's Inclusion
Radiology
Medical AI
Patient Psychosocial Health
CRISPR
Car-T Therapies

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

PublishesTwice weeklyEpisodes100Founded2 years ago
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Latest Episodes

In early 2025, the FDA was rocked by sweeping layoffs and leadership turnover, raising questions about whether the agency could maintain its pace in reviewing new drug applications.

By the end of the year, the approval picture told a more complicat... more

What does it really mean to put patients first in today’s life sciences landscape? In this sponsored episode of The Top Line, leaders from RTI Health Solutions explore how patient voices are transforming evidence generation, market access and medical... more

As artificial intelligence continues to dominate conversations across life sciences, many companies are reaching an inflection point between experimentation and real-world impact. In a recent episode of The Top Line, Mark Sullivan, president of regul... more

China has moved from a fast-following biotech market to a source of globally competitive innovation, according to Josh Smiley, president and chief operating officer of Zai Lab. Speaking on The Top Line podcast, Smiley traces the country’s evolution o... more

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Recent Guests

Mark Sullivan
President of Regulated Industries at Salesforce
Salesforce
Episode: Beyond the AI hype: How life sciences can turn agents into a competitive advantage (Sponsored)
Deepak Kuletha
Leads the data analytics group for biopharma services at Walgreens Pharmacy.
Walgreens
Episode: From data to decisions: how Walgreens is powering smarter pharma strategies (Sponsored)
Pam Traxel
American Cancer Society Cancer Action Network
American Cancer Society
Episode: Advocacy, access and the future of cancer care take center stage in new Health Matters episode (Sponsored)
Dr. Yesmean Wahdan
Senior Vice President and Head of Medical Affairs for US and North America at Bayer
Bayer Pharmaceuticals
Episode: Bayer’s collaborative model: Breaking silos to accelerate impact (Sponsored)
Christine Roth
Executive Vice President and Head of Global Product Strategy and Commercialization at Bayer Pharmaceuticals
Bayer Pharmaceuticals
Episode: Bayer’s collaborative model: Breaking silos to accelerate impact (Sponsored)
Christopher Shilling
Chief Regulatory Officer at Forge Biologics
Forge Biologics
Episode: PreCheck pulse check: What the industry is saying about FDA’s production initiative
Holly Dunn
Managing Partner of Performance at Havas Media Network, focusing on healthcare practice for pharma and wellness brands.
Havas Media Network
Episode: How Pharma Can Build Trust and Reach Patients in Health Marketplaces (Sponsored)
Brian Hilberdink
President of Boehringer Ingelheim's U.S. Human Pharma
Boehringer Ingelheim
Episode: How Boehringer Ingelheim is buttressing its US business
Marie Flanagan
Regulatory and AI Governance Lead Safety Technologies at IQVIA, with 20 years of experience in pharmacovigilance and technology.
IQVIA
Episode: AI is changing drug safety, but governance sets the guardrails (Sponsored)

Hosts

Ayla Ellison
Host of The Top Line, Editor-in-Chief at Fierce Pharma, and a prominent figure in health journalism.
Chris Hayden
Host of The Top Line and Producer at Fierce, contributing to insights on the biopharma industry.

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Talking Points

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China’s biotech moment goes global, Zai Lab exec says (Sponsored)
Q: What lessons can other biotechs learn from Zai's approach?
Josh emphasizes the importance of leveraging China's extensive patient base and speed, while also ensuring that development capabilities extend beyond China to support global ambitions.
China’s biotech moment goes global, Zai Lab exec says (Sponsored)
Q: How did Zai Lab achieve a balance between China's biotech speed and global development rigor?
Josh explains their collaborative approach with global biotech companies in phase three programs, ensuring adherence to global standards while leveraging local resources for efficiency.
China’s biotech moment goes global, Zai Lab exec says (Sponsored)
Q: What key shifts have you witnessed in the biotech landscape over time?
Josh discusses the move from me-too products in the Chinese market to innovative global medicines capable of competing on the world stage.
Beyond the AI hype: How life sciences can turn agents into a competitive advantage (Sponsored)
Q: Can you shed some light on how you're advising life science organizations on keeping a human in the loop as they adopt AI agents?
It's crucial to maintain human oversight in AI processes to ensure compliance and effective functioning, allowing for agency management that keeps both technological and human capital aligned.
Beyond the AI hype: How life sciences can turn agents into a competitive advantage (Sponsored)
Q: How are you helping life science companies make their agentic enterprise vision more of a reality?
We focus on leveraging both structured and unstructured data to create accurate and reliable AI agents, tailored for the pharmaceutical industry, enhancing their capabilities and trustworthiness.

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Frequently Asked Questions About The Top Line

What is The Top Line about and what kind of topics does it cover?

Exploring the dynamic landscape of the biopharma and medtech industries, discussions revolve around critical trends, innovations, and challenges facing these sectors each week. Journals dissect a range of topics, including mergers, marketing strategies, drug research and development, and advances in medical technology. The podcast frequently features insights from industry experts and leaders, offering listeners an in-depth look into the forces shaping the future of healthcare. Unique elements include episodes centered on women's leadership in life sciences and the evolving role of artificial intelligence in drug discovery and patient engagement.

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Which podcasts are similar to The Top Line?

These podcasts share a similar audience with The Top Line:

1. The Readout Loud
2. BioCentury This Week
3. HBR IdeaCast
4. Bold Names
5. The McKinsey Podcast

How many episodes of The Top Line are there?

The Top Line launched 2 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Top Line?

Recent guests on The Top Line include:

1. Mark Sullivan
2. Deepak Kuletha
3. Pam Traxel
4. Dr. Yesmean Wahdan
5. Christine Roth
6. Christopher Shilling
7. Holly Dunn
8. Brian Hilberdink

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