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Drug Development
Companion Diagnostics
Agilent Technologies
Precision Medicine
Adcs (antibody Drug Conjugates)
Oncology
Biotech
Next-Generation Sequencing
Immunohistochemistry
Women's Health Gap
Health Conditions Affecting Women
Sickle Cell Disease
Drug Approvals
Clinical Trials and Women's Inclusion
Women's Health Research
Medical AI
Radiology
Patient Psychosocial Health
CRISPR
Car-T Therapies

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

PublishesTwice weeklyEpisodes100Founded3 years ago
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Latest Episodes

Community oncology is playing an increasingly important role in how cancer care is delivered across the United States, with a growing share of patients treated outside large academic medical centers. In this sponsored episode of The Top Line, host Ch... more

The leaders of this year’s list of the most anticipated drug launches will likely come as no surprise: Fierce’s annual report on the biggest potential launches of 2026 details how the next obesity meds from Novo Nordisk and Eli Lilly are expected to ... more

Please see the following USPI, US ISI, EU SmPC and Canadian Product Monograph for complete LIVMARLI product information:

US Important Safety Information (livmarli.com/important-safety-information/)

US Prescribing Information (file... more

Artificial intelligence is reshaping medical communications, but it is not a substitute for human judgment. In this episode of The Top Line, experts from RTI Health Solutions explore how AI is being used across scientific writing, editing and informa... more

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Recent Guests

Ajay Narasimha
Senior Vice President of Corporate Strategy and Business Development at Mirum Pharmaceuticals
Mirum Pharmaceuticals
Episode: How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)
Gabriel Dardis
Scientific and communications strategist at RTI Health Solutions with more than eight years of experience
RTI Health Solutions
Episode: Why human expertise still matters in AI-driven med comms (Sponsored)
Frances Ramsey
Senior Information Services Specialist at RTI Health Solutions, with expertise in scientific evidence identification
RTI Health Solutions
Episode: Why human expertise still matters in AI-driven med comms (Sponsored)
Margaret Mathis
Director of Medical Editing at RTI Health Solutions, with over 20 years of experience in scientific editing and communication
RTI Health Solutions
Episode: Why human expertise still matters in AI-driven med comms (Sponsored)
Kate Liltman
Director of Scientific Strategy and Evidence Planning at RTI Health Solutions.
RTI Health Solutions
Episode: From approval to value: Why evidence storytelling now matters (Sponsored)
Sarah Muzetti-Jenkins
Principal medical writer with experience in oncology research and medical writing.
RTI Health Solutions
Episode: From approval to value: Why evidence storytelling now matters (Sponsored)
Jason Crouch
Graphic designer specializing in visual storytelling and data visualization.
RTI Health Solutions
Episode: From approval to value: Why evidence storytelling now matters (Sponsored)
Deepak Kuletha
Leads the data analytics group for biopharma services at Walgreens Pharmacy.
Walgreens
Episode: From data to decisions: how Walgreens is powering smarter pharma strategies (Sponsored)
Pam Traxel
American Cancer Society Cancer Action Network
American Cancer Society
Episode: Advocacy, access and the future of cancer care take center stage in new Health Matters episode (Sponsored)

Hosts

Ayla Ellison
Host of The Top Line, Editor-in-Chief at Fierce Pharma, and a prominent figure in health journalism.
Chris Hayden
Host of The Top Line and Producer at Fierce, contributing to insights on the biopharma industry.

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Talking Points

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How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)
Q: What is the driving factor in Mirum's successful business development strategies?
Ajay mentions that a commitment to patient needs and a disciplined approach to business development are key to their strategy, allowing them to make savvy deals that prioritize patient impact.
How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)
Q: How does this acquisition strengthen Mirum's pipeline going forward?
Ajay highlights that the acquisition meaningfully expands their pipeline with additional potential breakthrough therapies, thereby enhancing their late-stage development.
How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)
Q: How will this acquisition impact patients in the rare disease community?
Ajay explains that the acquisition will address a significant health economic burden for patients with hepatitis delta virus, an underserved population with no FDA-approved treatments.
How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)
Q: So I'm curious to hear why this acquisition is a good fit for Mirum.
Ajay elaborates that the acquisition of Bluejay Therapeutics checks all boxes for addressing high unmet needs and bringing in a transformative asset to maximize value and reach patients.
Biopharma's rebound keeping pace so far
Q: What did we see play out in terms of both the volume and the scale of transactions?
Last year's deal volume was unfortunately lower, but focused on true innovation and efficiency.

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Frequently Asked Questions About The Top Line

What is The Top Line about and what kind of topics does it cover?

Exploring the dynamic landscape of the biopharma and medtech industries, discussions revolve around critical trends, innovations, and challenges facing these sectors each week. Journals dissect a range of topics, including mergers, marketing strategies, drug research and development, and advances in medical technology. The podcast frequently features insights from industry experts and leaders, offering listeners an in-depth look into the forces shaping the future of healthcare. Unique elements include episodes centered on women's leadership in life sciences and the evolving role of artificial intelligence in drug discovery and patient engagement.

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These podcasts share a similar audience with The Top Line:

1. The Readout Loud
2. BioCentury This Week
3. HBR IdeaCast
4. Bold Names
5. WSJ Tech News Briefing

How many episodes of The Top Line are there?

The Top Line launched 3 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Top Line?

Recent guests on The Top Line include:

1. Ajay Narasimha
2. Gabriel Dardis
3. Frances Ramsey
4. Margaret Mathis
5. Kate Liltman
6. Sarah Muzetti-Jenkins
7. Jason Crouch
8. Deepak Kuletha

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