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Drug Development
Companion Diagnostics
Agilent Technologies
Precision Medicine
Adcs (antibody Drug Conjugates)
Oncology
Biotech
Next-Generation Sequencing
Immunohistochemistry
Women's Health Gap
Health Conditions Affecting Women
Sickle Cell Disease
Drug Approvals
Clinical Trials and Women's Inclusion
Women's Health Research
Medical AI
Radiology
Patient Psychosocial Health
CRISPR
Car-T Therapies

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

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Latest Episodes

With a new president of U.S. pharma at the helm—and two key FDA approvals now in the books—Boehringer Ingelheim is sharpening its focus on the lucrative American market.

In this week’s episode of “The Top Line,” we dive into Boehringer Ingelheim’s ... more

Artificial intelligence is reshaping drug safety, but governance is just as critical as innovation, according to Marie Flanagan of IQVIA Safety Technologies. Speaking on The Top Line podcast, Flanagan said responsibility for AI in healthcare must be ... more

Tariffs, drug pricing reform, a government shutdown and a major turnover at one of the world’s largest drugmakers all converged this week, leaving plenty to unpack for the industry as it heads into fall. Greater clarity on President Donald Trump’s ta... more

Despite a challenging year, the biotech industry has continued to push boundaries, taking bold risks in pursuit of groundbreaking science. If anything, this year has only strengthened our conviction in the rising stars leading the next wave of innova... more

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Recent Guests

Brian Hilberdink
President of Boehringer Ingelheim's U.S. Human Pharma
Boehringer Ingelheim
Episode: How Boehringer Ingelheim is buttressing its US business
Marie Flanagan
Regulatory and AI Governance Lead Safety Technologies at IQVIA, with 20 years of experience in pharmacovigilance and technology.
IQVIA
Episode: AI is changing drug safety, but governance sets the guardrails (Sponsored)
Dr. Freda Lewis-Hall
A psychiatrist and former chief medical officer of Pfizer
Pfizer
Episode: Rebuilding trust in pharma in the age of misinformation
Robert Abel
Chief Scientific Officer Platform at Schrödinger
Schrödinger
Episode: Schrödinger taps AI to speed drug discovery (Sponsored)
Glenn Pierce
Vice President of Medical at the World Federation of Hemophilia
World Federation of Hemophilia
Episode: Inside the commercial growing pains of hemophilia gene therapies
Dr. Scott Gottlieb
Former FDA Commissioner, Senior Fellow at the American Enterprise Institute, and influential voice in healthcare policy and regulation
American Enterprise Institute
Episode: Former FDA Chief Scott Gottlieb talks drug pricing, access and innovation (Sponsored)
Dr. Paul Offit
Director of the Vaccine Education Center and Attending Physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia
Children's Hospital of Philadelphia
Episode: Rebuilding trust: compassionate communication and public health (Sponsored)
Peter Pitts
A leading authority on healthcare policy, former FDA Associate Commissioner and current President of the Center for Medicine in the Public Interest.
Center for Medicine in the Public Interest
Episode: Peter Pitts talks FDA direction, industry communication (Sponsored)
Richard Francis
President and CEO of Teva
Teva
Episode: Teva’s CEO shares ‘Pivot to Growth’ progress

Hosts

Ayla Ellison
Host of the show, dedicated to unpacking complex biopharma and medtech stories for audiences.
Ryan Kersman
Executive Vice President, Global Public Affairs and Health Policy at GCI Health, focusing on communication strategies in healthcare.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#65
United States/News/Business News
Apple Podcasts
#51
United Kingdom/News/Business News
Apple Podcasts
#152
Canada/News/Business News
Apple Podcasts
#47
Australia/News/Business News
Apple Podcasts
#50
Germany/News/Business News
Apple Podcasts
#166
France/News/Business News
Apple Podcasts
#181
Italy/News/Business News
Apple Podcasts
#23
Singapore/News/Business News
Apple Podcasts
#30
Denmark/News/Business News
Apple Podcasts
#49
Sweden/News/Business News
Apple Podcasts
#52
South Korea/News/Business News
Apple Podcasts
#52
Poland/News/Business News
Apple Podcasts
#54
Russia/News/Business News
Apple Podcasts
#56
Finland/News/Business News
Apple Podcasts
#67
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Apple Podcasts
#69
Taiwan/News/Business News
Apple Podcasts
#73
Switzerland/News/Business News
Apple Podcasts
#77
Israel/News/Business News
Apple Podcasts
#81
Japan/News/Business News
Apple Podcasts
#86
China/News/Business News
Apple Podcasts
#89
India/News/Business News
Apple Podcasts
#91
Argentina/News/Business News
Apple Podcasts
#96
Philippines/News/Business News
Apple Podcasts
#100
Hong Kong/News/Business News
Apple Podcasts
#109
Belgium/News/Business News
Apple Podcasts
#115
Ireland/News/Business News
Apple Podcasts
#117
Netherlands/News/Business News
Apple Podcasts
#123
Brazil/News/Business News
Apple Podcasts
#136
Saudi Arabia/News/Business News
Apple Podcasts
#145
Singapore/News
Apple Podcasts
#148
Mexico/News/Business News
Apple Podcasts
#154
Spain/News/Business News
Apple Podcasts
#188
South Africa/News/Business News
Apple Podcasts
#226
United Arab Emirates/News/Business News

Talking Points

Recent interactions between the hosts and their guests.

How Boehringer Ingelheim is buttressing its US business
Q: How prepare are you for the rollouts of Zonkurtinib and Neurondomelast?
We are focusing on specialized sales resources for oncology and utilizing established strategies that worked for our existing products.
How Boehringer Ingelheim is buttressing its US business
Q: Could you talk specifically about how you plan to position Boehringer for growth in the US?
Focusing on treating underutilized conditions and ensuring clinical systems understand and use products like Jardiance more effectively.
How Boehringer Ingelheim is buttressing its US business
Q: What are your goals for the division since entering the role earlier this year?
To become a launch machine, commercializing innovative therapies while focusing on a balanced approach in therapy areas and core business.
AI is changing drug safety, but governance sets the guardrails (Sponsored)
Q: From a business standpoint, how do you prepare your organization and AI teams to leverage AI effectively while also controlling risk?
Start with guiding principles for responsible AI use in healthcare, which include risk-based approach, human oversight, validity and robustness, transparency, data privacy, fairness, and governance.
AI is changing drug safety, but governance sets the guardrails (Sponsored)
Q: But I think the big question here is who's making sure it's done responsibly?
Responsibility is a shared duty across multiple roles and governed by internal frameworks and external regulatory guidance.

Audience Metrics

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Frequently Asked Questions About The Top Line

What is The Top Line about and what kind of topics does it cover?

Focusing on the intersections of biopharma and medtech, this podcast provides listeners with insights into industry trends and developments. Weekly discussions feature journalists who analyze significant business news, including mergers, marketing strategies, drug research and development, as well as advancements in medical devices. The content is tailored for professionals in the healthcare and pharmaceutical sectors, offering not just news, but also critical analyses of how these trends impact the industry. Listeners can expect a blend of expert interviews, relevant updates, and a clear breakdown of complex topics to enhance understanding of the ongoing changes in the biopharma landscape.

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These podcasts share a similar audience with The Top Line:

1. BioCentury This Week
2. The Readout Loud
3. Biotech Hangout
4. Masters in Business
5. Bloomberg Intelligence

How many episodes of The Top Line are there?

The Top Line launched 2 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Top Line?

Recent guests on The Top Line include:

1. Brian Hilberdink
2. Marie Flanagan
3. Dr. Freda Lewis-Hall
4. Robert Abel
5. Glenn Pierce
6. Dr. Scott Gottlieb
7. Dr. Paul Offit
8. Peter Pitts

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