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Artwork for The Persistence Lab

The Persistence Lab

AbbVie
Abbvie
Autoimmune Diseases
Drug Development
Health Care Innovation
Blood-Brain Barrier
Biomarkers
Hyaluronic Acid Fillers
Neurodegenerative Diseases
Abbvie Complete Access
US Healthcare System
Packaging
Immune System
Reverse Translation
Cures
Prior Authorization
Health Literacy
Global Access Programs
Crohn's Disease
Tumor Agnostic Trials
Allergan Aesthetics

The Persistence Lab, sponsored by AbbVie, pulls back the curtain on the hard, human work of health care innovation. Each episode dives into a real problem in medicine or health care and follows the people who are working to develop solutions. With immersive sound design and a three-act structure that puts story first, this series showcases the fresh thinking, bold ideas, and the unexpected paths t... more

PublishesTwice monthlyEpisodes11Founded7 months ago
Number of ListenersCategories
ScienceHealth & Fitness

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Artwork for The Persistence Lab

Latest Episodes

We often experience science through the breakthrough announced in the news. But that moment comes at the end of a long and arduous process that often began years earlier. Understanding this journey, and the people who dedicate their careers to these ... more

Neurodegenerative diseases, like Alzheimer’s disease and Parkinson’s disease, are conditions that lead to a gradual, cumulative loss of neural activity in the brain. There are currently no cures for these conditions, and current care regimens focus o... more

Why do some patients with autoimmune disease respond to treatment while others may not? Understanding these insights can offer scientists potential clues about the underlying cause of disease. This episode, sponsored by AbbVie, explores the approache... more

The immune system is our greatest defense – a shield that protects us from harmful diseases. But what happens when it misfires and attacks the body with no pathogens in sight? For decades, scientists have been working to find ways to address the cond... more

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Recent Guests

Ole Graf
Dr. Ole Graf, Head of Neurodegenerative and Clinical Trial Transformation, Neuroscience Clinical Development at AbbVie
AbbVie
Episode: Can Scientists Slow Down Brain Disorders?
Jan Stoehr
Dr. Jan Stoehr, Senior Director, Movement Disorders Head, Neuroscience Discovery Research at AbbVie
AbbVie
Episode: Can Scientists Slow Down Brain Disorders?
Heath Guay
Head of Precision Medicine Immunology at AbbVie
AbbVie
Episode: Not Lost in Translation
Corey Wallace
Vice President, Clinical Development, Immunology at AbbVie
AbbVie
Episode: Not Lost in Translation
Dr. Anne Eldred
Head of Early Programs, Immunology, Clinical Development at AbbVie
AbbVie
Episode: The Answer Is Inside You: The Complexities of Autoimmune Research
Dr. John Sedgwick
Senior Vice President and Global Head Discovery Research at AbbVie
AbbVie
Episode: The Answer Is Inside You: The Complexities of Autoimmune Research
Darren Messina
Senior Vice President of Allergan Aesthetics, R&D
AbbVie/Allergan Aesthetics
Episode: Beyond the Skin's Surface
Lisa Espinoza
Owner and medical director of La Chalet Medical Aesthetics
La Chalet Medical Aesthetics
Episode: Beyond the Skin's Surface
Shilpan Patel
Head of Asset and Lung Oncology Clinical Development, AbbVie
AbbVie
Episode: Cancer's Clues: How Biomarkers are Changing the Game for Scientists

Host

Kira Dineen
Co-host/host with multiple appearances; spelling varies in source data.

Reviews

4.6 out of 5 stars from 39 ratings
  • Well produced

    Well produced and interesting perspectives. Easy to listen to and enlightening on the development process.

    Apple Podcasts
    5
    Alljessedup
    United States4 months ago
  • Great podcast!!

    Informative and interesting podcast that gives great perspectives on innovation at AbbVie and the pharma industry as a whole. Worth a listen!

    Apple Podcasts
    5
    Andi Dare
    United States6 months ago
  • Gives me hope

    Loved hearing about the people who make medicines a reality. Keep up the good work!

    Apple Podcasts
    5
    Mojalu
    United States6 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Highlights the people behind medicine and patient impact.
Well produced and informative perspectives; easy to listen to.
Shows practical innovation insights in pharma and medicine.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#192
Canada/Science

Talking Points

Recent interactions between the hosts and their guests.

The Answer Is Inside You: The Complexities of Autoimmune Research
Q: How are AbbVie teams collaborating across disciplines to accelerate progress in autoimmune research?
The teams emphasize cross-therapy-area learning, leadership alignment, and sharing insights to identify common drivers of disease, thereby accelerating the translation of basic science into targeted therapies, such as biologics, genetic medicines, and precision medicine approaches.
Smart Packaging
Q: So let's go deeper into that. When you think about everything that goes into protecting the product, what does the packaging process actually look like from the very beginning?
It starts with cross-functional planning, designing the primary packaging to provide a moisture, oxygen, and light barrier, then integrating labeling and cartonization, while considering the entire lifecycle and patient needs from day one.
Entering the Fortress: Navigating the Blood-Brain Barrier
Q: So, how do scientists even begin to approach creating medicines that could cross the blood-brain barrier?
It starts with trial and error for small molecules to see how much crosses and then using chemistry to improve permeability, while for protein-based drugs the crossing rate is extremely low, necessitating clever delivery strategies and optimization.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About The Persistence Lab

What is The Persistence Lab about and what kind of topics does it cover?

A biomedically focused series that pulls back the curtain on health care innovation by foregrounding the people solving tough medical problems. Across episodes, topics span tissue-based drug development, biomarker-guided therapies, precision medicine, patient access and education, as well as related challenges like the blood-brain barrier, aesthetics science, and evolving trial designs. The show often centers on how teams collaborate across discovery, development, and patient-facing programs to translate science into real-world outcomes, with a strong emphasis on human stories, practical learnings, and the evolving regulatory and technology landscape. A standout thread is the commitment to transparency about failures and iterative learning,... more

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Which podcasts are similar to The Persistence Lab?

These podcasts share a similar audience with The Persistence Lab:

1. Hidden Brain
2. Radiolab
3. The Indicator from Planet Money
4. The Daily
5. Life Kit

How many episodes of The Persistence Lab are there?

The Persistence Lab launched 7 months ago and published 11 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Persistence Lab?

Recent guests on The Persistence Lab include:

1. Ole Graf
2. Jan Stoehr
3. Heath Guay
4. Corey Wallace
5. Dr. Anne Eldred
6. Dr. John Sedgwick
7. Darren Messina
8. Lisa Espinoza

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