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Artwork for The Chain: Protein Engineering Podcast

The Chain: Protein Engineering Podcast

Cambridge Healthtech Institute
Machine Learning
AI and Drug Discovery
Artificial Intelligence
Clinical Trials
Drug Development
Biologics
Antibody Discovery
Antibody-Drug Conjugates
FDA
Regulatory Oversight
Pharmacovigilance
Data Security
Drug Discovery
Gpcrs
Oncology
Antibody Engineering
Antibodies
Bispecific Antibody Drug Conjugates
Bispecific Antibodies
Antibody-Drug Conjugates (adcs)

The Chain explores the lives, careers, research, and discoveries of protein engineers and scientists, the impact their work is having on the field, and where the industry is headed. Tune in to stay up-to-date on the newest advancements and to hear the stories that are impacting the world of biologics.

PublishesMonthlyEpisodes80Founded6 years ago
Number of ListenersCategories
Life SciencesScience

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Artwork for The Chain: Protein Engineering Podcast

Latest Episodes

September 16, 2025 | With the rise of AI and automation, what is the core human skill in drug discovery that is and will be valuable in the future? Derek Lowe, director of Chemical Biology Therapeutics at Novartis and author of the In the Pipeline bl... more

August 12, 2025 | Diagonal Therapeutics founder and CEO Alexey Lugovskoy discusses the key lessons learned over his illustrious career, starting from his childhood in the Soviet Union to founding his own company, Diagonal Therapeutics. With host Tari... more

July 15, 2025 | Are licensing fees required or gatekeeping? In this episode of The Chain, host Nimish Gera, vice president of Biologics at Mythic Therapeutics, and Ian Wilkinson, CEO of Gamma Proteins, discuss accessing antibody discovery technology ... more

June 10, 2025 | In this bonus episode of The Chain, Daniel Chen, MD, PhD, founder and CEO of Synthetic Design Lab, returns for the Science Commune segment and speaks with Keith Flaherty, MD, FAACR, professor of Medicine of Harvard Medical School and ... more

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Recent Guests

Ian Wilkinson
Founder and executive in antibody engineering with experience across multiple startups.
Gamma Proteins, Mapsolve, Absolute Antibody
Episode: Episode: 75 - Are Licensing Fees Required or Gatekeeping?
Pamela Barney
An HR expert with over 35 years of experience working in biotech and biopharma organizations.
AbbVie
Episode: Episode: 72 - Pamela Barney on HR Lessons to Meet the Needs of Biotech
Jessica Stark
Professor at MIT and researcher in glycobiology and cancer immunology
Massachusetts Institute of Technology
Episode: PEGS Young Scientist Keynote Jessica Stark on the Role of Glycans in Cancer Research
Andreas Plückthun
Professor of Biochemistry and Director of the Department of Biochemistry at the University of Zurich
University of Zurich
Episode: Episode: 70 - Views on Machine Learning and AI in the Antibody and Protein Engineering Space
Sir Greg Winter
Nobel Laureate and pioneer in therapeutic antibodies
Episode: Episode: 69 - Conversation with Sir Greg Winter on the 50th Anniversary of the Milstein and Köhler Paper
Randolph Lopez
CTO and co-founder of A-Alpha Bio, focusing on protein-protein interaction technologies
A-Alpha Bio
Episode: Episode: 68 - Changing the Game of Protein-Protein Interactions With Randolph Lopez
Dr. Tony Tolcher
World famous clinical oncologist, founder of NEXT Oncology
NEXT Oncology
Episode: Episode: 67 - Anthony Tolcher Discusses Oncology, Dual-Payload Technology, and the ADC Field
John Lambert
An icon in the antibody-drug conjugate field and a prolific advisor and consultant.
Episode: Episode: 66 - John Lambert on Antibody Drug Conjugates Then, Now, & Beyond
Dr. Tariq Ghayur
Scientific advisor and entrepreneur in residence at FairJourney Biologics, with over 30 years of experience in biologics discovery programs.
FairJourney Biologics
Episode: Episode 65- Tariq Ghayur on the Renaissance of Bispecifics and ADCs, AI, and More

Reviews

4.9 out of 5 stars from 48 ratings
  • Very informative! It’s great to hear so many different perspectives.

    Very informative! It’s great to hear so many different perspectives.

    Apple Podcasts
    5
    PP(penguin person)!
    United States2 years ago
  • Quality content that helps to drive the industry forward

    Looking forward to more!

    Apple Podcasts
    5
    Kirrikane
    United States2 years ago
  • Great info - thank you!

    Great info - thank you!

    Apple Podcasts
    5
    Ejhealey
    United States2 years ago
  • This podcast is great for scientists looking to learn about how proteins are used in industry and hear stories of experienced scientists in these fields. Highly recommended to young scientists looking to see what's out there.

    Audible
    5
    Bravo
    United States4 years ago
  • Great science podcast

    This podcast is great for scientists looking to learn about how proteins are used in industry and hear stories of experienced scientists in these fields. Highly recommended to young scientists looking to see what's out there.

    Audible
    5
    Bravo
    United States4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Many highlight the diversity of guests and the depth of knowledge shared, making the content very educational.
Listeners appreciate the insightful discussions on the latest advancements in biotechnology and protein engineering.
Several comments note the podcast's role in supporting industry professionals with valuable perspectives and advice.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem
Q: What do you think about the commercialization of AI and potential oversell in digital biotech startups?
I think there may be a bubble with AI in biotech that could burst, leading to investor disillusionment.
Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem
Q: What do you think is the long-term impact of funding cuts to scientific research in the US?
It will take years to notice, but we're harming the capabilities in scientific research that drive innovation in the country.
Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem
Q: With the rise of AI and automation, what should individuals in drug discovery focus on?
Focus should be on larger questions like disease targeting and therapeutic areas, which AI cannot currently address.
Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem
Q: What do you think is the core human skill in drug discovery that is valuable today, that will continue to be valuable in the future?
The ability to work at a higher level, tackling bigger issues rather than grunt work that can be automated.
Alexey Lugovskoy Shares Decades of Experience in Starting Out and Founding Companies
Q: What is your vision for Diagonal in three to five years?
He hopes Diagonal will be a clinical stage company delivering medicines to patients and continue to build an innovative pipeline.

Audience Metrics

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Frequently Asked Questions About The Chain: Protein Engineering Podcast

What is The Chain: Protein Engineering Podcast about and what kind of topics does it cover?

Focusing on the intricate world of protein engineering, content often involves interviews with influential scientists and industry leaders who share their experiences in biopharmaceuticals, biologics, and the advancements in therapeutic techniques. Listeners can expect discussions around trends in antibody engineering, immunotherapy, and the evolving technology landscape, including the integration of artificial intelligence in drug development. The podcast uniquely emphasizes personal journeys within the scientific field, providing insights not only on the technical aspects of their work but also the challenges faced by professionals in the life sciences industry.

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How many listeners does The Chain: Protein Engineering Podcast get?

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Which podcasts are similar to The Chain: Protein Engineering Podcast?

These podcasts share a similar audience with The Chain: Protein Engineering Podcast:

1. BioCentury This Week
2. Biotech Hangout
3. The Readout Loud
4. Ground Truths
5. Science Magazine Podcast

How many episodes of The Chain: Protein Engineering Podcast are there?

The Chain: Protein Engineering Podcast launched 6 years ago and published 80 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Chain: Protein Engineering Podcast?

Recent guests on The Chain: Protein Engineering Podcast include:

1. Ian Wilkinson
2. Pamela Barney
3. Jessica Stark
4. Andreas Plückthun
5. Sir Greg Winter
6. Randolph Lopez
7. Dr. Tony Tolcher
8. John Lambert

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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