The Cancer Letter

National Cancer Institute

FDA

National Institutes Of Health

Vinay Prasad

Richard Pazdur

HPV

Financial Toxicity

Cancer Centers

ASCO

The Cancer Letter

Intermediate Endpoints

NCI

Oncology

Anthony Letai

Cervical Cancer

City Of Hope

Multi-Cancer Detection (MCD)

The Wistar Institute

Christianacare Graham Cancer Center

Early Onset Colorectal Cancer

The Cancer Letter, an independent weekly news publication, has been the leading source for information on the issues that shape oncology since 1973. With a dedicated audience of oncology’s leaders, The Cancer Letter stays on top of breaking news and advances in oncology, providing authoritative, award-winning coverage of the development of cancer therapies, drug regulation, legislation, cancer res... more

8 ratings

Publishes	Twice weekly	Episodes	97	Founded	a year ago
Number of Listeners		Categories	MedicineHealth & Fitness

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Latest Episodes

A new diagnostic lens—and a lasting scientific legacy

In this week's episode of The Cancer Letter Podcast, editor and publisher Paul Goldberg, and associate editor Jacquelyn Cobb revisit two of last week’s most-read stories: the growing recognition that early-onset colorectal cancer requires a new diagn... more

8 Jul 2026 • 23 min

Breaking down Operation Trailblazer: Rolling INDs, outside expert submission help, and one-trial requirement

In this week’s episode of The Cancer Letter Podcast, Paul Goldberg, editor and publisher of The Cancer Letter, and Sara Willa Ernst, reporter, break down HHS’ latest vision for the future: Operation Trailblazer.

The report is titled: “HHS Roadmap t... more

1 Jul 2026 • 22 min

YouTube

The Directors: Two Midwest directors tell us about the challenging healthcare economics in rural areas

“Institutions are feeling crunched at so many different directions”

How’s this for a paradox:

The better cancer centers become at keeping patients alive, the more expensive cancer care becomes.

This brutal tradeoff hits harder in rural areas, wher... more

26 Jun 2026 • 49 min

YouTube

Policy by way of podcaster—FDA issues priority vouchers after Joe Rogan episode on psychedelics

In this week's episode of The Cancer Letter Podcast, Paul Goldberg, editor and publisher, and Sara Willa Ernst, reporter, go on a trip into the world of federal health policy surrounding psychedelic medicine.

In April, FDA issued National Priority ... more

24 Jun 2026 • 22 min

YouTube

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Recent Guests

Mark Burkard

Director of the University of Iowa Health Care Holden Cancer Center

University of Iowa Health Care Holden Comprehensive Cancer Center

Episode: The Directors: Two Midwest directors tell us about the challenging healthcare economics in rural areas

Jeffrey Miller

Director of the University of Minnesota Masonic Cancer Center

University of Minnesota Masonic Cancer Center

Episode: The Directors: Two Midwest directors tell us about the challenging healthcare economics in rural areas

Peter Garrett

Founder and executive director of Patient Action for Cancer Research; former director of External Affairs at the National Cancer Institute

Patient Action for Cancer Research; National Cancer Institute

Episode: Peter F. Garrett to people with cancer: Your story has power

Marcel van den Brink

President of City of Hope, microbiome researcher

City of Hope

Episode: As FDA’s wheels almost entirely come off, NCI remains sturdy—a cancer moonshot may even be on the horizon

Amarintha Curtis

Medical Director Gibbs Cancer Center and Research Institute; PI Upstate Carolina NCORP

Gibbs Cancer Center and Research Institute; Upstate Carolina NCORP

Episode: The Directors: NCORP PIs discuss the growing complexity of regulatory oversight in clinical cancer research

Jeffrey Berenberg

Co-PI Hawaii Minority and Underserved NCORP; core clinical member for translational and clinical research

Hawaii NCORP; University of Hawaii Cancer Center

Episode: The Directors: NCORP PIs discuss the growing complexity of regulatory oversight in clinical cancer research

John Byrd

Director of UPMC Hillman Cancer Center, Associate Vice Chancellor for Cancer Affairs at the University of Pittsburgh

UPMC Hillman Cancer Center; University of Pittsburgh

Episode: The Directors: Byrd and Chapman speak about avoiding catastrophism and using bridge funding to keep labs open

Andrew Chapman

Director of the Sidney Kimmel Cancer Center at Jefferson Health; Executive Vice President of Oncology Services

Sidney Kimmel Cancer Center at Jefferson Health

Episode: The Directors: Byrd and Chapman speak about avoiding catastrophism and using bridge funding to keep labs open

Otis Brawley

Prominent physician and commentator on cancer policy and screening

The Cancer Letter interviewee

Episode: No need for a speculum? A new era of HPV screening

Hosts

Paul Goldberg

Host of The Cancer Letter Podcast; The Cancer Letter; longtime journalist covering oncology, policy, and funding

Jacquelyn Cobb

Associate editor hosting with Paul; on-the-ground reporting and editorial perspective

Chart Rankings

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Apple Podcasts

#151

Singapore/Health & Fitness/Medicine

Talking Points

Recent interactions between the hosts and their guests.

In The Headlines: Kimryn Rathmell, ASCO, and “an important time in cancer research”

Q: What is your message to junior faculty members about staying in the field given funding pressures?

The advice focuses on doubling down on bold, innovative ideas, leveraging opportunities in early career grants, and maintaining enthusiasm for a meaningful career path in cancer research, especially as new funding streams and collaboration opportunities emerge.

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Q: How might the rapid evolution of testing technology affect the trial's relevance by the time results are available?

Researchers acknowledge that technology can evolve quickly, which could render initial endpoints less relevant and require adaptive or ongoing assessment to stay aligned with current capabilities.

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Q: What are the main design challenges of a tri-arm Vanguard-type trial where one arm tests a modality, another arm tests a different modality, and a control group is involved?

Key concerns include whether participants in the control group will seek testing outside the study, how to prevent bias, and how to ensure the trial can still yield meaningful conclusions about mortality versus survival endpoints.

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Q: Is early detection always good, especially when discussing very early stages where outcomes are not yet known?

The hosts and researchers explain that early detection can be beneficial in some contexts but can also cause harm in others due to uncertainties at the earliest stages, hence the need for careful evaluation of benefits versus harms.

In the Headlines: MD Anderson’s Pisters on doing “something gigantic for pediatric cancer”

Q: And how did the idea for the collaboration between MD Anderson and Texas Children's come about?

The idea emerged from a long-held belief in the speaker's career that unifying programs, education, and research across two top institutions could create the largest pediatric oncology effort in the nation, culminating in a joint facility.

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Frequently Asked Questions About The Cancer Letter

What is The Cancer Letter about and what kind of topics does it cover?

A weekly briefing on oncology policy, funding, regulation, and science, featuring sharp discussions with oncologists, researchers, center leaders, policymakers, and industry strategists. Episodes commonly explore FDA decisions, NCI funding, screening guidelines, NCORP and community trials, and the interplay between public policy and patient care. The show often pairs reporters or editors with high-profile guests to unpack complex regulatory and clinical developments, provide historical context, and translate breakthroughs into practical implications for centers, researchers, and patients. Noteworthy throughlines include the Moonshot era's legacy, the evolving role of screening and prevention, and the challenges of sustaining cancer programs... more

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How many subscribers and views does The Cancer Letter have?

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Which podcasts are similar to The Cancer Letter?

These podcasts share a similar audience with The Cancer Letter:

1. Consider This from NPR
2. Hard Fork
3. The Daily
4. The NPR Politics Podcast
5. The Opinions

How many episodes of The Cancer Letter are there?

The Cancer Letter launched a year ago and published 97 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact The Cancer Letter?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

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What guests have appeared on The Cancer Letter?

Recent guests on The Cancer Letter include:

1. Mark Burkard
2. Jeffrey Miller
3. Peter Garrett
4. Marcel van den Brink
5. Amarintha Curtis
6. Jeffrey Berenberg
7. John Byrd
8. Andrew Chapman

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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