Rephonic
Artwork for The BioInsights Podcast

The BioInsights Podcast

BioInsights
Cell and Gene Therapy
Lipid Nanoparticles
FDA
Gene Delivery
Potency Assays
Drug Delivery Systems
Market Access
N. Loram Foundation
Nanorare Diseases
Gene Therapy
Zolgensma
Quality Control
Novo Nordisk
Nanomaterials
Pharmaceutical Industry
Rna-Targeted Drugs
Central Nervous System
Ionis Pharmaceuticals
Advanced Therapies
Automation In Assays

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

PublishesInfrequentlyEpisodes61Founded4 years ago
Number of ListenersCategories
ScienceLife SciencesBusiness

Listen to this Podcast

Artwork for The BioInsights Podcast

Latest Episodes

The one‑and‑done model has defined gene therapy for a generation. Chris Hopkins thinks it is time to move on. At ASGCT 2026, Abi Pinchbeck spoke with the Co‑founder and CEO of Glafabra Therapeutics on redoseable cell‑based gene therapy, a platform sp... more

Lauren Coyle, Launch Commissioning Editor, Bioconjugate Insights, speaks with Weston Kightlinger, CEO, Ridge Bio, about the challenge of DAR heterogeneity and site specificity in ADC development, Ridge Bio’s ML‑driven enzyme and linker engineering pl... more

Lauren Coyle, Launch Commissioning Editor, Bioconjugate Insights, speaks with Antoine Yver, Board Chair, Ona Therapeutics, with more than three and a half decades of experience shaping global cancer drug development. In this conversation, they explor... more

In this interview, Róisin McGuigan, Editor, Nucleic Acid Insights, and Jesse Erasmus, Director of Virology at HDT Bio, discuss current challenges and opportunities in RNA safety, manufacturing, and targeted delivery, and the key ongoing obstacles fac... more

Key Facts

Accepts Guests
Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

Similar Podcasts

People also subscribe to these shows.

NEJM This Week
NEJM This WeekNEJM Group

Recent Guests

Weston Kightlinger
CEO and co-founder of Ridge Bio
Ridge Bio
Episode: Precision by design: engineering site‑specific ADCs with machine learning
Antoine Yver
Chair of the board for Ona Therapeutics; veteran oncology executive
Ona Therapeutics
Episode: Crossing the ADC inflection points: what separates clinical success from failure
Jesse Erasmus
Director of Virology
HDT Bio
Episode: Formulation and delivery of RNA-based vaccines and therapeutics: addressing outstanding questions around safety and purity
Trevor Hallam
Chief Scientific Officer at Sail Biomedicines
Sail Biomedicines
Episode: Advancing nucleic acid therapeutics with circular RNA
Vince Rotello
Professor of Chemistry, University of Massachusetts Amherst
University of Massachusetts Amherst
Episode: Exploring advances in bioconjugation: nanozymes, tissue tropism, and the future of responsive systems
Kerstin Hofer
Science and People Lead at Roche
Roche
Episode: The promise of antibody-oligonucleotide conjugates for neurological diseases
Rohin Iyer
Senior Director of Global Cell and Gene Therapy Operations at Marken
Marken – Advanced Therapies Division (ATD)
Episode: From innovation to access: bridging gaps in scalability and cold chain precision logistics for advanced therapies
Ryan Lahr
Senior R&D scientist with over 15 years in the biotech industry
Cellscript
Episode: Enhancing mRNA results through strategic RNA design and quality control
Ketaki Deshmukh
A senior scientist specializing in optimizing LNP formulations through high throughput screening techniques.
Novo Nordisk
Episode: Exploring challenges, opportunities and state-of-the-art tools in the lipid nanoparticle space

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Crossing the ADC inflection points: what separates clinical success from failure
Q: What do you see as the most critical translational inflection points when looking at ADCs, from bench to bedside?
The two key inflection points are the non-clinical package and the first-in-human transition. Alongside a deep MOA and robust pharmacology alignment, they determine whether an ADC can move forward with credible efficacy and manageable safety.
Exploring advances in bioconjugation: nanozymes, tissue tropism, and the future of responsive systems
Q: Can you explain why nanosomes and in-situ catalysis hold promise for diagnostics and therapeutics?
Nanosomes enable catalytic amplification in diagnostics and imaging, allowing pro-fluorophores to become fluorescent in tissues and enabling in situ drug activation at disease sites, potentially increasing efficacy while reducing systemic exposure.
Exploring advances in bioconjugation: nanozymes, tissue tropism, and the future of responsive systems
Q: What are the biggest challenges in translating nanoparticle bioconjugates from lab to clinic?
The key obstacles include protein corona formation masking targeting ligands and triggering RES clearance, which concentrates nanoparticles in liver and spleen. Overcoming these issues requires designs that preserve targeting functionality while avoiding rapid systemic clearance.
Exploring advances in bioconjugation: nanozymes, tissue tropism, and the future of responsive systems
Q: What sparked your journey into bioconjugation research and how did your focus evolve over time?
Rotello describes starting in natural product synthesis, moving into supramolecular chemistry, and progressively embracing multivalency and nanoparticles. He explains how初 his work shifted from protein denaturation to binding, delivery, and finally in vivo-directed bioconjugation as the essential frontier due to the limitations observed in vivo versus in vitro.
Advancing nucleic acid therapeutics with circular RNA
Q: So bearing these challenges in mind, how can utilizing circular RNA help address them? And what unique benefits does it offer compared to other forms of RNA?
Trevor explains that circular RNA offers greater durability and a longer duration of translation, enabling more sustained protein production while allowing control through translation initiation mechanisms and IRS tuning, which can mitigate toxicity and improve dosing efficiency.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About The BioInsights Podcast

What is The BioInsights Podcast about and what kind of topics does it cover?

The show consistently centers on translating cutting-edge biologics from concept to clinic, with a strong emphasis on antibody–drug conjugates, RNA-based therapeutics, bioconjugation chemistry, and advanced therapies logistics. Episodes often feature industry leaders and researchers who dissect translational challenges, such as safety, pharmacology, delivery, and manufacturing, while sharing real-world case studies, frameworks for decision-making, and the evolving tech stack—from ML-driven design to cold-chain and global distribution. A notable strength is the breadth of guests, ranging from university-level experts to biotech executives, which helps illuminate both scientific and operational facets of bringing complex biologics to market. ... more

Where can I find podcast stats for The BioInsights Podcast?

Rephonic provides a wide range of podcast stats for The BioInsights Podcast. We scanned the web and collated all of the information that we could find in our comprehensive podcast database. See how many people listen to The BioInsights Podcast and access YouTube viewership numbers, download stats, audience demographics, chart rankings, ratings, reviews and more.

How many listeners does The BioInsights Podcast get?

Rephonic provides a full set of podcast information for three million podcasts, including the number of listeners. View further listenership figures for The BioInsights Podcast, including podcast download numbers and subscriber numbers, so you can make better decisions about which podcasts to sponsor or be a guest on. You will need to upgrade your account to access this premium data.

What are the audience demographics for The BioInsights Podcast?

Rephonic provides comprehensive predictive audience data for The BioInsights Podcast, including gender skew, age, country, political leaning, income, professions, education level, and interests. You can access these listener demographics by upgrading your account.

How many subscribers and views does The BioInsights Podcast have?

To see how many followers or subscribers The BioInsights Podcast has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to The BioInsights Podcast?

These podcasts share a similar audience with The BioInsights Podcast:

1. NEJM This Week

How many episodes of The BioInsights Podcast are there?

The BioInsights Podcast launched 4 years ago and published 61 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact The BioInsights Podcast?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for The BioInsights Podcast?

Rephonic pulls ratings and reviews for The BioInsights Podcast from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.

View all the reviews in one place instead of visiting each platform individually and use this information to decide if a show is worth pitching or not.

How do I access podcast episode transcripts for The BioInsights Podcast?

Rephonic provides full transcripts for episodes of The BioInsights Podcast. Search within each transcript for your keywords, whether they be topics, brands or people, and figure out if it's worth pitching as a guest or sponsor. You can even set-up alerts to get notified when your keywords are mentioned.

What guests have appeared on The BioInsights Podcast?

Recent guests on The BioInsights Podcast include:

1. Weston Kightlinger
2. Antoine Yver
3. Jesse Erasmus
4. Trevor Hallam
5. Vince Rotello
6. Kerstin Hofer
7. Rohin Iyer
8. Ryan Lahr

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

Find and pitch the right podcasts

We help savvy brands, marketers and PR professionals to find the right podcasts for any topic or niche. Get the data and contacts you need to pitch podcasts at scale and turn listeners into customers.
Try it free for 7 days