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Artwork for Real Talk: Eosinophilic Diseases

Real Talk: Eosinophilic Diseases

American Partnership for Eosinophilic Disorders
Eosinophilic Esophagitis
Social Vulnerability
APFED
Esophageal String Test
Medical Billing
Health Insurance
Eosinophilic Diseases
Eosinophils
Bone Mineral Density
Endoscopy
Science Fair
Thymic Stromal Lymphopoietin
EGID Partners Registry
Electronic Health Records
Pediatric Gastroenterology
Eosinophilic Disorders
Emergency Care Costs
Clinical Trials
Eosinophilic Gastrointestinal Disease
PPI

Eosinophils are a type of white blood cell that play a role in immune responses and help fight off infections. When these cells build up and cause inflammation in the digestive system, tissues, organs, and/or bloodstream, without a known cause, it may be the result of an eosinophil-associated disease. Join the American Partnership for Eosinophilic Disorders (APFED) for a series of conversations wi... more

PublishesMonthlyEpisodes57Founded5 years ago
Number of ListenersCategories
MedicineHealth & Fitness

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Artwork for Real Talk: Eosinophilic Diseases

Latest Episodes

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Science Advisory Counci... more

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Science Advisory Counci... more

Co-hosts Ryan Piansky, a patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Angelic... more

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Counc... more

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Recent Guests

Phillip Arceneaux
Patient advocate living with EOE since 2019
Individual with EOE; educator/advocate
Episode: Community Conversation: EoE
Dr. Oko
Clinical research and medical affairs professional
Duke University Hospital, Department of Gastroenterology and Transplant Hepatology
Episode: Clinical Trials
Angelica Lackey Mirzoca
Fourth-year medical student studying EoE social vulnerability research at UNC
University of North Carolina School of Medicine
Episode: Social Vulnerability and EoE
Jessica Grady
Patient advocate living with EOE
Unspecified
Episode: Community Conversation: EoE and Life Transitions
Beth Morgan
Medical billing advocate with expertise in navigating billing and insurance
Episode: Tips for Understanding Your Medical Bills
Fei Li Kuang
Assistant professor in Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, physician-scientist
Northwestern University Feinberg School of Medicine
Episode: HOPE on the Horizon
Dr. Evan Dellon
Adjunct professor of epidemiology; director of the UNC Center for Esophageal Diseases and Swallowing
University of North Carolina School of Medicine
Episode: Predictors of not using medication for EoE
Dr. Elizabeth Jensen
Professor of epidemiology with expertise in reproductive perinatal pediatric epidemiology
Wake Forest University School of Medicine; University of North Carolina at Chapel Hill
Episode: Predictors of not using medication for EoE
Dr. Andrew Lee
Vice President, Clinical Research at Uniquity Bio
Uniquity Bio
Episode: TSLP and EoE: Exploring the Science Behind a Potential Treatment Target

Hosts

Ryan Piansky
Co-host; patient advocate; speaker on eosinophilic disease topics
Holly Knotowicz
Co-host; speech-language pathologist; co-host for APFED discussions

Reviews

4.9 out of 5 stars from 10 ratings
  • Fantastic resource for Eosinophilic Diseases!

    I was diagnosed with EoE and felt very unsupported and under informed by my GI doctor. I’ve really appreciated all the professionals you’ve had on and the hosts are sweet and personable. I feel more empowered and equipped to have informed conversations with my providers after listening to this podcast. Thank you.

    Apple Podcasts
    5
    Lstar7897
    United Statesa year ago
  • So informative!

    I was recently diagnosed with EoE and was desperate for information. I stumbled onto this podcast and found it so informative and professionally done. A real life saver for me! Thank you!

    Apple Podcasts
    5
    sscavo44
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guest variety enhances credibility with patients and clinicians alike.
Hosts are personable and professional, adding warmth to complex topics.
Content covers practical topics like billing, trials, and care coordination.
Helpful resource for those with EoE; empowers patients to discuss with providers.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Community Conversation: EoE and Life Transitions
Q: What motivated you to participate in clinical trials?
I joined because I was desperate for more options and answers, and clinical trials offered access to newer therapies and the possibility of relief from ongoing endoscopies and symptoms.
TSLP and EoE: Exploring the Science Behind a Potential Treatment Target
Q: What are the translational implications of the mouse model findings for human treatment?
The mouse model shows a correlation between increased TSLP and esophageal inflammation, and importantly, that blocking TSLP reduces inflammation; this supports ongoing human trials of TSLP blockers for EOE and possibly other diseases.
TSLP and EoE: Exploring the Science Behind a Potential Treatment Target
Q: Why is TSLP relevant for people with eosinophilic esophagitis?
Genetic and laboratory evidence point to TSLP being upstream in the inflammatory cascade, essential for initiating eosinophil activation and the broader allergic inflammatory response seen in EOE.
TSLP and EoE: Exploring the Science Behind a Potential Treatment Target
Q: But for our listeners who may not be familiar, what is TSLP and can you pronounce it again?
TSLP stands for thymus stromal lymphopoietin; it is an alarm signal that initiates type 2 inflammatory responses, activating eosinophils and other immune cells, thereby driving inflammation in mucosal tissues such as the esophagus.
Predictors of not using medication for EoE
Q: What are the next steps for this research in terms of expanding the data sources?
We plan to add more sites to increase sample size, expand to less common outcomes, and follow up on initial findings to better understand long-term implications and treatment strategies.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Real Talk: Eosinophilic Diseases

What is Real Talk: Eosinophilic Diseases about and what kind of topics does it cover?

This series centers eosinophilic disorders with a practical angle: patients, caregivers, and clinicians discuss lived experiences, treatment options, and navigating healthcare systems. Recent episodes cover clinical trials, social determinants of health, medical billing, and real-world patterns in medication use, plus scientific angles like TSLP and bone health in children. A notable value is the mix of patient voices, clinician expertise, and researchers translating complex science into accessible guidance, making it a useful resource for anyone seeking actionable information, advocacy tips, and updates on emerging therapies.

What stands out is the focus on real-world challenges (billing, access, telehealth), the emphasis on patient-cente... more

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Which podcasts are similar to Real Talk: Eosinophilic Diseases?

These podcasts share a similar audience with Real Talk: Eosinophilic Diseases:

1. The Mel Robbins Podcast
2. On Purpose with Jay Shetty
3. Juicy Scoop with Heather McDonald
4. The Ezra Klein Show
5. AAAAI Podcast: Conversations from the World of Allergy

How many episodes of Real Talk: Eosinophilic Diseases are there?

Real Talk: Eosinophilic Diseases launched 5 years ago and published 57 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Real Talk: Eosinophilic Diseases?

Recent guests on Real Talk: Eosinophilic Diseases include:

1. Phillip Arceneaux
2. Dr. Oko
3. Angelica Lackey Mirzoca
4. Jessica Grady
5. Beth Morgan
6. Fei Li Kuang
7. Dr. Evan Dellon
8. Dr. Elizabeth Jensen

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