Rephonic
Artwork for Practical AI in Healthcare
Artificial Intelligence
AI In Healthcare
Healthcare
Clinical Trials
Patient Engagement
Data Quality
Pharmaceutical Industry
Patient Care
Generative AI
Clinical Decision Support
Patient Empowerment
Mental Health
Real World Evidence
Electronic Health Records
Clinical Research
Healthcare Governance
AI Literacy
Data Integration
Eversana
Healthcare AI

AI promises to transform healthcare—but real, scalable impact remains rare. Practical AI in Healthcare cuts through the noise to showcase real-world use cases delivering business value today. Hosted by senior leaders— former VPs of life science technology groups, clinical informatics professionals from top-tier organizations, and a former Big Four consultant—each episode features candid conversati... more

PublishesWeeklyEpisodes36Founded8 months ago
Number of ListenersCategories
MedicineHealth & Fitness

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Artwork for Practical AI in Healthcare

Latest Episodes

When physician Barry Chaiken was diagnosed with prostate cancer, his clinical training gave way to fear. It took a friend asking, "What are you doing?" to snap him back into doctor-mode thinking. That experience reshaped how he sees AI in healthcare.... more

In Part 2 of our conversation with Matt Truppo, Global Head of Research Platforms and Computational R&D at Sanofi, we move from discovery to development, where the real stakes begin. Matt unpacks the promise and limitations of “digital patient twins,... more

Ted Shortliffe built MYCIN at Stanford in the 1970s, one of the first medical AI systems ever deployed in a clinical setting. Five decades later, he joins Steve and Leon to examine what has persisted in clinical decision support — above all, the dema... more

AI in drug discovery has been long on promise and short on delivery. Matt Truppo, Global Head of Research Platforms and Computational R&D at Sanofi, presents a different picture. His team used AI to identify 10+ novel drug targets in 12 months, scree... more

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Recent Guests

Matt Truppo
Global Head of Research Platforms and Computational R&D at Sanofi
Sanofi
Episode: S1, E34 - Matt Truppo, PhD, Part 2: AI-Driven Drug Development at Sanofi: Clinical Trials, Regulatory, and Personal AI
Ted Shortliffe
Chair Emeritus, Columbia University Department of Biomedical Informatics; AI pioneer in medicine
Columbia University
Episode: S1, E33 - Ted Shortliffe, MD, PhD: 50 Years of Clinical AI
Amy Price
Editor-in-Chief, Journal of Participatory Medicine; researcher
Dartmouth Health
Episode: S1, E30 - Amy Price: Patient Advocacy, Participatory Medicine, and AI Governance
Shashi Shankar
Co-founder & CEO of Novellia, Inc.
Novellia
Episode: S1, E29 - Shashi Shankar, Co-founder & CEO, Novellia, Inc.
Adam Blum
Founder of CancerBot, patient advocate
CancerBot
Episode: S1, E28 - Adam Blum: AI-Powered Clinical Trial Matching
Charlie Harp
CEO of Clinical Architecture
Clinical Architecture
Episode: S1, E27 - Charlie Harp, Healthcare Data Quality and the PIQI Framework
Giovanni Donatelli
CEO of The Language Group, founder of Fetch translation technology
The Language Group
Episode: S1, E26 - Discharge Planning Translation Services with Giovanni Donatelli
Dr. Robert Wachter
Chair of Medicine at UCSF; author of A Giant Leap
UCSF
Episode: S1, E24 - Bob Wachter, MD | A Giant Leap: AI in Healthcare
Amar Mandavia
Clinical psychologist and informatician, research assistant professor at Boston University
National Center for PTSD, VA Boston
Episode: S1, E23 - CHiRP: AI-Enabled Early Detection of Psychosis Risk with Amar Mandavia, PhD & Enrique "Kike" Gutiérrez, PhD

Hosts

Dr. Steven Labkoff
Host with expertise in clinical informatics and healthcare delivery.
Dr. Leon Rozenblit
Co-host focusing on the integration of AI in healthcare practice.

Reviews

4.9 out of 5 stars from 8 ratings
  • Thanks

    This is such an informative and accessible podcast. You guys do such a fantastic job of teasing out key points and nuanced details by asking provocative questions, but relating this to a general audience.

    Apple Podcasts
    5
    DBoffa
    United States3 months ago
  • Gratitude for practical get your hands dirty thoughtfulness

    Thrilled to find this thoughtful resource! Exactly the practical approach I’ve been wanting to think through the use of AI as a tool versus magic. Can’t wait to listen to the other episodes. Thank you!

    Apple Podcasts
    4
    Mksutherland
    United States7 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners appreciate the practical approach taken in each episode, expressing gratitude for the thoughtful insights into AI's applications in healthcare.
The resourceful discussions resonate well with those seeking to understand AI as a tangible tool rather than a theoretical concept.
Many are excited about the potential impact of AI discussed in the podcasts and look forward to future episodes.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

S1, E34 - Matt Truppo, PhD, Part 2: AI-Driven Drug Development at Sanofi: Clinical Trials, Regulatory, and Personal AI
Q: How do you handle the tension between AI-generated content and the need for human-in-the-loop validation in regulatory documents and responses to agency questions?
AI assists with drafting and information gathering, but final submissions and regulatory responses remain human-authored. We focus on transparent data inputs, explainable models, and expert review to ensure accuracy, safety, and regulatory compliance, while using GenAI to accelerate drafting and responsiveness to regulators.
S1, E34 - Matt Truppo, PhD, Part 2: AI-Driven Drug Development at Sanofi: Clinical Trials, Regulatory, and Personal AI
Q: What is the AI kicker for trial execution and site-facing operations—how is AI actually changing trial feasibility, site selection, and monitoring in a tangible way?
AI-enabled data harmonization and a clinical control tower give a single source of truth for trial data, enabling real-time site performance monitoring, better recruitment trajectory predictions, and proactive risk flagging. The system helps select sites, forecast supply needs, and monitor patient flow, reducing site burden and speeding up decision-making across programs.
S1, E32 - Matt Truppo, PhD: AI-Driven Drug Discovery at Sanofi
Q: What would that have looked like before AI-driven target ID and biomarker approaches, and how does AI change the ROI story?
Matt explains that AI accelerates data synthesis, enables rapid cross-target comparisons, and surfaces novel biomarkers and target ideas that would have required far more time and multiple expert reviews, dramatically shortening discovery timelines and expanding the potential target space while maintaining governance and validation.
S1, E29 - Shashi Shankar, Co-founder & CEO, Novellia, Inc.
Q: So, Shashi, how did you get into this role and what's your background?
Shashi describes a transition from Genentech and Roche into entrepreneurship, driven by data gaps and a personal loss to cancer, which motivated him to create a patient-centered data company that consolidates records across care sites.
S1, E28 - Adam Blum: AI-Powered Clinical Trial Matching
Q: How does CancerBot extract and manage trial eligibility attributes?
They use a prompt-workbench guided by subject-matter experts to derive disease-specific attributes (e.g., 84 attributes for follicular lymphoma), applying long, carefully tuned prompts to ensure accuracy well above traditional methods.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Practical AI in Healthcare

What is Practical AI in Healthcare about and what kind of topics does it cover?

The content shares insightful discussions on the practical implementation of artificial intelligence in the healthcare sector. Episodes feature conversations with industry experts, doctors, and researchers, focusing on real-world applications of AI technologies, their impacts on patient care, and the emerging challenges in clinical settings. Topics range from early intervention strategies in mental health, the role of real-world evidence in clinical research, to the application of AI in cancer diagnosis and healthcare governance. This podcast stands out by prioritizing tangible insights and ethical considerations, making it a valuable resource for healthcare professionals eager to understand the integration of AI in their fields.

Listeners... more

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Which podcasts are similar to Practical AI in Healthcare?

These podcasts share a similar audience with Practical AI in Healthcare:

1. NEJM AI Grand Rounds
2. The Daily
3. The AI Daily Brief: Artificial Intelligence News and Analysis
4. The Weekly Show with Jon Stewart
5. Odd Lots

How many episodes of Practical AI in Healthcare are there?

Practical AI in Healthcare launched 8 months ago and published 36 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Practical AI in Healthcare?

Recent guests on Practical AI in Healthcare include:

1. Matt Truppo
2. Ted Shortliffe
3. Amy Price
4. Shashi Shankar
5. Adam Blum
6. Charlie Harp
7. Giovanni Donatelli
8. Dr. Robert Wachter

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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