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Artwork for Oncology Brothers: Practice-Changing Cancer Discussions

Oncology Brothers: Practice-Changing Cancer Discussions

Oncology Brothers
Immunotherapy
Non-Small Cell Lung Cancer
Chemotherapy
Small Cell Lung Cancer
Renal Cell Carcinoma
Neuroendocrine Tumors
Diffuse Large B-Cell Lymphoma
Bladder Cancer
Pancreatic Cancer
Breast Cancer
Acute Myeloid Leukemia
Clinical Trials
Her2-Positive Breast Cancer
Nivolumab
Multiple Myeloma
Chronic Myeloid Leukemia
Prostate Cancer
FDA Approval
Pembrolizumab
Lung Cancer

The Oncology Brothers Podcast, led by Drs. Rahul and Rohit Gosain, is dedicated to bridging the gap between academic cancer centers and community oncology in the ever-evolving field of hematology & oncology. With a mission to disseminate crucial information to the medical community, this oncology podcast is not for medical advice but rather serves as a beacon for physicians, nurses, trainees, and ... more

PublishesTwice weeklyEpisodes291Founded4 years ago
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MedicineHealth & Fitness

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Artwork for Oncology Brothers: Practice-Changing Cancer Discussions

Latest Episodes

In this episode of the Oncology Brothers podcast, we dived deep into the complexities of second-line treatment options for multiple myeloma, with a special focus on CAR T-cell therapy. Joined by experts Dr. Rafael Fonseca, a multiple myeloma speciali... more

Welcome to the Oncology Brothers podcast! In this episode, we dived into the world of CAR T-cell therapy, featuring insights from hematology experts Drs. Luciano Costa and Shernan Holtan.

Join us as we explore:

• The basics of CAR T-cell therapy an... more

Welcome to the Oncology Brothers podcast! In this episode, we were joined by Dr. Ronak Mistry, a hematologist from Penn Medicine, for a rapid-fire round addressing common questions about thrombocytopenia.

We dived into a variety of topics, including... more

In this episode of the Oncology Brothers podcast, we dived into two challenging cases of small cell lung cancer (SCLC) to explore the latest supportive care options, the role of prophylactic cranial irradiation (PCI), and the sequencing of available ... more

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Recent Guests

Shernan Holtan
Hematology expert and clinician at Roswell Park
Roswell Park
Episode: CAR-T Cell Therapy in Multiple Myeloma & Lymphoma - Clinical Foundations
Luciano Costa
Hematology expert discussing CAR T-cell therapy for multiple myeloma
Episode: CAR-T Cell Therapy in Multiple Myeloma & Lymphoma - Clinical Foundations
Ronak Mistry
Hematologist at Penn Medicine and co-host of The Fellows On Call
Penn Medicine
Episode: Rapid Fire Rounds - Thrombocytopenia Workup & Management with Dr. Ronak Mistry
Estela Rodriguez
Physician from University of Miami
University of Miami
Episode: Challenging Cases in Small Cell Lung Cancer (SCLC) - Drs. Estela Rodriguez & Misty Shields
Misty Shields
Physician from Indiana University
Indiana University
Episode: Challenging Cases in Small Cell Lung Cancer (SCLC) - Drs. Estela Rodriguez & Misty Shields
Christine Lovly
Thoracic medical oncologist
City of Hope
Episode: WCLC 2026 Highlights: MAVERICK, ADAURA, HARMONi, PAPILLON, DESTINY-Lung04 with Dr. Christine Lovly
Shruti Patel
GI specialist from Stanford University
Stanford University
Episode: Managing Toxicities of HER2+ Therapies in Upper GI Cancer - Trastuzumab, T-DXd, Zanidatamab
Sam Cytryn
GI oncologist from Memorial Sloan Kettering
Memorial Sloan Kettering Cancer Center
Episode: Managing Toxicities of HER2+ Therapies in Upper GI Cancer - Trastuzumab, T-DXd, Zanidatamab
Sam Klempner
GI medical oncologist
Mass General Hospital
Episode: Upper GI Treatment Algorithm (Esophageal, Gastric, GEJ) - Dr. Sam Klempner

Hosts

Rahul Gosain
Co-host of the Oncology Brothers Podcast; physician specializing in oncology with clinical practice in community setting
Rohit Gosain
Co-host of the Oncology Brothers Podcast; physician specializing in oncology with clinical practice in community setting

Reviews

4.8 out of 5 stars from 128 ratings
  • Go to Resource for Oncology Updates

    The Oncology brothers do an excellent job of bridging the gap between academia and community oncology. They provide timely oncology updates and discuss the clinical impact, diving into practice changing discussion with guest experts. Hands down my go to resource for oncology updates 🙌

    Apple Podcasts
    5
    Hemoncdoc_
    United Statesa month ago
  • Oncology Brothers: Setting a New Standard in Medical Education

    The Oncology Brothers have become a go-to in my week. They take the constant firehose of oncology data—new FDA approvals, shifting algorithms, and “practice-changing” abstracts—and turn it into something practical I can actually use in clinic the next day. The conversations feel like sitting down with smart colleagues who care about evidence, clarity, and real-world decision making, not just reciting trial slides. It’s exactly the kind of thoughtful, high-yield education our field needs more of.... more

    Apple Podcasts
    5
    DD1384
    United States10 months ago
  • Excellent Resource

    I regularly listen to this podcast and find it an excellent reference for oncology practice. The speakers consistently provide valuable insights that are both practical and informative. It's a great resource for staying updated and enhancing clinical knowledge.

    Apple Podcasts
    5
    RHJ, MD
    United Statesa year ago
  • Insightful, relatable, and essential for anyone in the oncology community

    The Oncology Brothers consistently deliver relevant, easy-to-digest insights on complex data and evolving treatment landscapes. Their ability to break down key updates—especially for those who can't attend every conference—is incredibly valuable. A must-listen for anyone in oncology looking to stay current and connected to the community.

    Apple Podcasts
    5
    OncoScriber
    United Statesa year ago
  • Stage IV CRC

    Thank you so much for putting this together! Love the updates of ongoing research! I am the primary caretaker for my 79 year old dad who was diagnosed 6/24 with stage IV CRC MSS KRAS G13D TMB-H, so love your GI updates from ASCO ‘25 and subcutaneous nivo, which we are considering. Hope you do more like bot/bal and neodadjuvant single cycle pembro. Thanks for taking the time to do this!!

    Apple Podcasts
    5
    mama4travel
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Audience notes the hosts' clear communication and evidence-based approach
Community oncologists appreciate real-world sequencing and toxicity management guidance
Physicians praise practical, high-yield education that translates to day-to-day practice
Listeners value concise updates on rapidly evolving oncology data

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

WCLC 2026 Highlights: MAVERICK, ADAURA, HARMONi, PAPILLON, DESTINY-Lung04 with Dr. Christine Lovly
Q: What are we learning from this update, and are you using CT DNA to monitor, especially if someone is having side effects from Osimertinib, to discontinue this regimen less than three year time?
Lovly said the ADAURA update reinforces adjuvant osimertinib after surgery for early-stage EGFR-mutant lung cancer. She sometimes uses circulating tumor DNA but does not escalate treatment based on a positive result alone because evidence and guidance for acting on molecular recurrence are lacking; she may increase scan frequency.
WCLC 2026 Highlights: MAVERICK, ADAURA, HARMONi, PAPILLON, DESTINY-Lung04 with Dr. Christine Lovly
Q: What did the MAVERICK study show, and moving forward in your practice, who would you consider PCI for?
Lovly said MRI surveillance can be used for limited or extensive stage small cell lung cancer in place of prophylactic cranial irradiation, reducing its potential toxicity while supporting cognitive failure-free survival.
Rapid Fire Rounds - Thrombocytopenia Workup & Management with Dr. Ronak Mistry
Q: How do you differentiate between ITP, atypical HUS, or TTP, especially when that patient is inpatient, and while we are awaiting ADAMTS13, how are you managing these patients?
ITP is more often isolated thrombocytopenia with no symptoms or mucocutaneous bleeding, while TTP and atypical HUS commonly involve anemia, hemolysis, and schistocytes. Use the PLASMIC score when schistocytes are present; for a high score, start plasma exchange while awaiting ADAMTS13 results.
Rapid Fire Rounds - Thrombocytopenia Workup & Management with Dr. Ronak Mistry
Q: How can we differentiate between inherited thrombocytopenia versus mild ITP?
Assess whether low counts are longstanding, ask about family history and bleeding with procedures, and look for associated conditions. A response to steroids can support ITP when the diagnosis remains uncertain.
CAR-T Cell Therapy in Multiple Myeloma & Lymphoma - Clinical Foundations
Q: What is holding therapy? What is bridging therapy?
Holding therapy is used before T-cell collection to control disease while preserving T-cell fitness. Bridging therapy is given after collection while cells are manufactured, with the goal of keeping the cancer controlled without targeting the same antigen or compromising CAR T-cell effectiveness.

Audience Metrics

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

A concise, practitioner-focused show that translates cutting-edge oncology data into practical guidance for community clinicians. Episodes frequently feature hematology/oncology specialists from top academic centers who discuss treatment sequencing, real-world toxicity management, and emerging therapies across cancers like multiple myeloma, DLBCL, AML, and solid tumors such as pancreatic and breast cancer. Dialogues center on translating conference highlights, trial data, and evolving guidelines into actionable decision-making for frontline and relapsed settings, with an emphasis on patient quality of life and team-based care. Noteworthy are the frequent cross-center collaborations, deep dives into sequencing decisions, and a clear aim to b... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Two Onc Docs
2. Oncology Today with Dr Neil Love
3. JAMA Clinical Reviews
4. Research To Practice | Oncology Videos
5. OncLiveÂŽ On Air

How many episodes of this podcast are there?

this podcast launched 4 years ago and published 291 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Shernan Holtan
2. Luciano Costa
3. Ronak Mistry
4. Estela Rodriguez
5. Misty Shields
6. Christine Lovly
7. Shruti Patel
8. Sam Cytryn

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