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Artwork for Oncology Brothers: Practice-Changing Cancer Discussions

Oncology Brothers: Practice-Changing Cancer Discussions

Oncology Brothers
Immunotherapy
Non-Small Cell Lung Cancer
Chemotherapy
Renal Cell Carcinoma
Neuroendocrine Tumors
Diffuse Large B-Cell Lymphoma
Bladder Cancer
Small Cell Lung Cancer
Pancreatic Cancer
Breast Cancer
Acute Myeloid Leukemia
Hepatocellular Carcinoma
Multiple Myeloma
Clinical Trials
Her2-Positive Breast Cancer
Nivolumab
Chronic Myeloid Leukemia
Prostate Cancer
Colorectal Cancer
FDA Approval

The Oncology Brothers Podcast, led by Drs. Rahul and Rohit Gosain, is dedicated to bridging the gap between academic cancer centers and community oncology in the ever-evolving field of hematology & oncology. With a mission to disseminate crucial information to the medical community, this oncology podcast is not for medical advice but rather serves as a beacon for physicians, nurses, trainees, and ... more

PublishesDailyEpisodes287Founded4 years ago
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Artwork for Oncology Brothers: Practice-Changing Cancer Discussions

Latest Episodes

Welcome to the Oncology Brothers podcast! In this episode, we were joined by Dr. Christine Lovly, a thoracic medical oncologist from City of Hope, to discuss key studies presented at the World Conference on Lung Cancer 2026.

We dived into five pivot... more

Welcome to the Oncology Brothers podcast! In this episode, we dived into the latest advancements in HER2-targeted therapies for upper gastrointestinal malignancies, with Drs. Shruti Patel and Samuel Cytryn.

Join us as we discussed:

• The recent app... more

Welcome to the Oncology Brothers podcast! In this episode, we were joined by Dr. Samuel Klempner, a GI medical oncologist from the Massachusetts General Hospital, to discuss the evolving treatment landscape for upper gastrointestinal cancers, specifi... more

In this episode of the Oncology Brothers podcast, we welcomed Dr. Jonathan Friedberg, a leading lymphoma expert, to discuss modern treatment approaches for follicular lymphoma and mantle cell lymphoma.

Join us as we explored:

• The diagnostic worku... more

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Recent Guests

Sam Klempner
GI medical oncologist
Mass General Hospital
Episode: Upper GI Treatment Algorithm (Esophageal, Gastric, GEJ) - Dr. Sam Klempner
Jonathan Friedberg
World-renowned lymphoma expert
Wilman Cancer Institute
Episode: Follicular & Mantle Cell Lymphoma Treatment Algorithm: Dr. Jonathan Friedberg
Mark Goldsmith
CEO of Revolution Medicines
Revolution Medicines
Episode: Revolution Medicines CEO Dr. Mark Goldsmith: Daraxonrasib dream to reality
Erica Mayer
Breast Medical Oncologist
Dana-Farber Cancer Institute
Episode: Camizestrant + CDK 46i FDA Approval in Hormone Receptor Positive Breast Cancer SERENA-6
John Mascarenhas
MPN specialist from Mount Sinai, New York
Mount Sinai, New York
Episode: SURPASS-ET: FDA Approval of Ropeginterferon alfa-2b in Essential Thrombocythemia (ET)
Nico Gagelmann
Oncologist; expert in myelofibrosis; previously University of Hamburg, Germany; currently Dana-Farber Cancer Institute, Boston
University of Hamburg; Dana-Farber Cancer Institute
Episode: Myelofibrosis Treatment Algorithm Discussion: Dr. Nico Gagelmann
Brandi Reeves
MPN specialist
Episode: Managing Toxicities of Therapies in Polycythemia Vera (PV) / Essential Thrombocythemia (ET)
Naveen Pemmaraju
MPN specialist
Episode: Managing Toxicities of Therapies in Polycythemia Vera (PV) / Essential Thrombocythemia (ET)
Andrew Kuykendall
MPN Specialist from Moffitt Cancer Center
Moffitt Cancer Center
Episode: VERIFY: FDA Approval of Rusfertide in Polycythemia Vera (PV) - Dr. Andrew Kuykendall

Hosts

Rahul Gosain
Co-host of the Oncology Brothers Podcast; physician specializing in oncology with clinical practice in community setting
Rohit Gosain
Co-host of the Oncology Brothers Podcast; physician specializing in oncology with clinical practice in community setting

Reviews

4.8 out of 5 stars from 118 ratings
  • Oncology Brothers: Setting a New Standard in Medical Education

    The Oncology Brothers have become a go-to in my week. They take the constant firehose of oncology data—new FDA approvals, shifting algorithms, and “practice-changing” abstracts—and turn it into something practical I can actually use in clinic the next day. The conversations feel like sitting down with smart colleagues who care about evidence, clarity, and real-world decision making, not just reciting trial slides. It’s exactly the kind of thoughtful, high-yield education our field needs more of.... more

    Apple Podcasts
    5
    DD1384
    United States9 months ago
  • Excellent Resource

    I regularly listen to this podcast and find it an excellent reference for oncology practice. The speakers consistently provide valuable insights that are both practical and informative. It's a great resource for staying updated and enhancing clinical knowledge.

    Apple Podcasts
    5
    RHJ, MD
    United Statesa year ago
  • Insightful, relatable, and essential for anyone in the oncology community

    The Oncology Brothers consistently deliver relevant, easy-to-digest insights on complex data and evolving treatment landscapes. Their ability to break down key updates—especially for those who can't attend every conference—is incredibly valuable. A must-listen for anyone in oncology looking to stay current and connected to the community.

    Apple Podcasts
    5
    OncoScriber
    United Statesa year ago
  • Stage IV CRC

    Thank you so much for putting this together! Love the updates of ongoing research! I am the primary caretaker for my 79 year old dad who was diagnosed 6/24 with stage IV CRC MSS KRAS G13D TMB-H, so love your GI updates from ASCO ‘25 and subcutaneous nivo, which we are considering. Hope you do more like bot/bal and neodadjuvant single cycle pembro. Thanks for taking the time to do this!!

    Apple Podcasts
    5
    mama4travel
    United States2 years ago
  • Onc Doc in the communty

    I have been following your content on X/Twitter and now I love that I can access these interviews here. Great work, much appreciated when things are moving so fast in this field.

    Apple Podcasts
    5
    Jimzz24
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Audience notes the hosts' clear communication and evidence-based approach
Community oncologists appreciate real-world sequencing and toxicity management guidance
Physicians praise practical, high-yield education that translates to day-to-day practice
Listeners value concise updates on rapidly evolving oncology data

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Revolution Medicines CEO Dr. Mark Goldsmith: Daraxonrasib dream to reality
Q: How do you balance the excitement of a breakthrough with concerns about safety and toxicity?
We proceeded cautiously, anticipated potential issues, and designed protocols to manage side effects effectively, ensuring patients could stay on therapy with manageable toxicity.
Revolution Medicines CEO Dr. Mark Goldsmith: Daraxonrasib dream to reality
Q: What was your reaction to early signs of efficacy at the first dose levels, and how did that influence dosing decisions?
Early signals of stable disease and reductions in circulating tumor DNA at low doses gave us confidence, and when we hit 80 milligrams we observed tumor shrinkage, which validated moving forward with higher, effective doses.
Revolution Medicines CEO Dr. Mark Goldsmith: Daraxonrasib dream to reality
Q: What sparked your shift from clinical practice to industry, and how has that shaped your approach to drug development?
My drive came from wanting to understand science deeply to make a real human impact; the move to industry allowed me to leverage resources and teams to tackle big problems at scale, bridging science, medicine, and business.
Follicular & Mantle Cell Lymphoma Treatment Algorithm: Dr. Jonathan Friedberg
Q: What are the considerations when choosing post-induction strategies and surveillance in FL?
Maintenance rituximab is increasingly questioned due to lack of demonstrated overall survival benefit and infection risk; surveillance imaging is used judiciously, with two-year and longer-term patterns guiding relapse management; in selected cases, TP53 testing is less central in FL but critical in mantle cell lymphoma for risk stratification.
Follicular & Mantle Cell Lymphoma Treatment Algorithm: Dr. Jonathan Friedberg
Q: How do you decide frontline therapy for follicular lymphoma with varying tumor burdens?
For asymptomatic, low-tumor-burden FL, observation is reasonable, though single-agent rituximab can yield very long-term responses; for high tumor burden or symptomatic disease, choices include BR, R-CHOP, or RCVP, with ongoing trials comparing rituximab-based regimens to newer agents.

Audience Metrics

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

A concise, practitioner-focused show that translates cutting-edge oncology data into practical guidance for community clinicians. Episodes frequently feature hematology/oncology specialists from top academic centers who discuss treatment sequencing, real-world toxicity management, and emerging therapies across cancers like multiple myeloma, DLBCL, AML, and solid tumors such as pancreatic and breast cancer. Dialogues center on translating conference highlights, trial data, and evolving guidelines into actionable decision-making for frontline and relapsed settings, with an emphasis on patient quality of life and team-based care. Noteworthy are the frequent cross-center collaborations, deep dives into sequencing decisions, and a clear aim to b... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Two Onc Docs
2. Oncology Today with Dr Neil Love
3. JAMA Clinical Reviews
4. Research To Practice | Oncology Videos
5. OncLive® On Air

How many episodes of this podcast are there?

this podcast launched 4 years ago and published 287 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Sam Klempner
2. Jonathan Friedberg
3. Mark Goldsmith
4. Erica Mayer
5. John Mascarenhas
6. Nico Gagelmann
7. Brandi Reeves
8. Naveen Pemmaraju

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