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Artwork for Two Onc Docs

Two Onc Docs

Sam and Karine
Immunotherapy
Chemotherapy
Oncology
Prostate Cancer
Small Cell Lung Cancer
Acute Myeloid Leukemia
Renal Cell Carcinoma
Testicular Cancer
Bladder Cancer
Chronic Lymphocytic Leukemia
Multiple Myeloma
Breast Cancer
Radiation Therapy
Infusion Reactions
Cancer Treatment
Metastatic Colon Cancer
Radiation Oncology
Localized Breast Cancer
Non-Small Cell Lung Cancer
Venetoclax

This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established... more

PublishesWeeklyEpisodes199Founded4 years ago
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Artwork for Two Onc Docs

Latest Episodes

Today we are recapping exciting GU data presented at the 2026 ASCO Annual Meeting in bladder cancer, kidney cancer, and prostate cancer.

This week’s episode will be focusing on the 2026 ASCO Plenary that received a standing ovation, the RASolute 302 trial.

The RASolute 302 trial is a landmark phase 3 study demonstrating that daraxonrasib doubled overall survival compared to chemother... more

Today we will be focusing on exciting data to come at the ASCO Annual Meeting in 2026 in Chicago, with a special focus on GU sessions, educational sessions & med ed sessions.

This week’s episode will be focusing on Von Willebrand disease (VWD), a highly testable bleeding disorder. We will go over all the important details on the diagnosis, types of VWD as well as treatment.

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Recent Guests

Dr. Michael Pishvaian
Special guest discussing pancreatic cancer, supportive care, and trials
[not explicitly stated in transcript]
Episode: Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 3
Michael Pishvaian
Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center; GI oncologist specializing in pancreatic cancer
Johns Hopkins University
Episode: Localized Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 1
Dr. Marc Carrier
Guest expert on thrombosis and cancer
Unknown (presenter)
Episode: Venous Thromboembolism (VTE) in Cancer Part 2
Marc Carrier
Head, Division of Hematology, Ottawa Hospital; Professor and Senior Scientist; expert in venous thromboembolism and cancer
Ottawa Hospital / University of Ottawa
Episode: Venous Thromboembolism (VTE) in Cancer Part 1
Dr. Ria Kraft
Radiation oncologist and host of the YouTube channel Rad Onc Talks
Rad Onc Talks
Episode: Rad Onc 101 Part 2
Dr. Chadi Nabhan
Chief Medical Officer of Right AI and host of Healthcare Unfiltered
Right AI
Episode: Career Pathways in Heme/Onc with Special Guest Dr. Chadi Nabhan
Krystle Zuniga
Board Certified Specialist in Oncology Nutrition
Episode: Oncology Nutrition 101 Part 2
Dr. Krystle Zuniga
Board-certified specialist in oncology nutrition with over 14 years of experience
Episode: Oncology Nutrition 101 Part 1
Dr. Tom Powles
Professor of Oncology at Queen Mary University and director of Barts Cancer Center.
Barts Cancer Center
Episode: Localized Kidney Cancer x Uromigos 2025 UPDATES (Part 1)

Hosts

Sam
Host of the show focused on hematology/oncology board review; multiple affiliations listed as Two Onc Docs.
Karine
Co-host focusing on hematology/oncology board review; frequently partnered with Sam.

Reviews

4.8 out of 5 stars from 307 ratings
  • Quick and concise

    I’m an RN in Hematology, and this podcast helped me to pass my OCN exam. The Onc Emergencies and BMT episodes were especially helpful. There is NO FLUFF in here, just quick, quality information So awesome to have an audio resource for multitasking for busy people!

    Apple Podcasts
    5
    Amanda in Utah
    United States6 months ago
  • Exceptional resource for board prep

    This podcast is truly exceptional. I'm immensely grateful for this podcast. Every episode is incredibly high-yield and perfectly tailored for hematology/oncology board prep. I especially loved the concise, easy-to-follow format, which made even the most complex topics feel approachable. It became my constant companion during car rides and treadmill sessions and it genuinely made a huge difference in my exam preparation. Thank you so much for creating such an invaluable resource.

    Apple Podcasts
    5
    ShivaniDalal
    United States6 months ago
  • Great refreshers

    Heme/onc fellow. Love listening to these for a quick refresher or update on high yield points. Or ideas/inspo for chalk talks on rounds. Thanks for the hard work to produce!

    Apple Podcasts
    5
    Sarahh1220
    United States7 months ago
  • The literal best

    Such a great high yield summary of important topics. Sam and Karine are lifesavers for hosting this amazing podcast which came so handy for board prep!

    Apple Podcasts
    5
    whowouldaknown
    United States7 months ago
  • Clear and concise

    Not a doc but an onc pharmacist and this podcast has been my favorite to study to! I love the short, digestible episodes with clear and concise content.

    Apple Podcasts
    5
    yourfavepharmd
    United States9 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Hosts are knowledgeable and keep content tightly focused.
Community-friendly and supportive for trainees.
Short episodes are perfect for commuting; very store-valuable for exams.
Great resource for fellows and practicing clinicians.
High-yield, concise board review with no fluff.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 3
Q: What inspired you to start Tumor Board Tuesday?
The idea originated during COVID to discuss cancer care online with a molecular angle, expanding from GI cancer to multiple cancer types, and to use expert-led case discussions to anchor conversations in current literature and emerging data.
Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 3
Q: What career advice would you give trainees or early career oncologists?
Pick a path within oncology due to increasing specialization; focus intensely on a disease type (GI, breast, lung, etc.) and build deep expertise, as being a general oncologist will be harder. Maintain strong scientific literacy to stay connected with translational advances, and seek a role in focused clinical centers or hybrid community settings that allow depth in a chosen area.
Metastatic Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 2
Q: What are the first-line systemic treatment options for metastatic pancreatic cancer?
Frontline regimens include FOLFIRINOX and Nab-paclitaxel (NabPaclitaxel), with Nelliorifox and related regimens offering similar potential benefits; choice depends on performance status, tolerance, and regional practice patterns, with ongoing debate about optimal regimens in different populations.
Metastatic Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 2
Q: What is the treatment if there is local recurrence after surgery in the pancreas or the surgical bed?
If symptomatic, radiation can palliate pain and GI issues; if not symptomatic, treatment decisions follow the approach for metastatic disease, with chemotherapy or targeted therapies depending on patient status and goals.
Venous Thromboembolism (VTE) in Cancer Part 1
Q: Which anticoagulant should be used for initial treatment of a VTE in cancer?
Most patients can start a direct oral anticoagulant such as rivaroxaban or apixaban, with low-molecular-weight heparin as an alternative in certain scenarios.

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Frequently Asked Questions About Two Onc Docs

What is Two Onc Docs about and what kind of topics does it cover?

Short, high-yield board-review episodes focused on hematology and oncology topics. Listeners get concise, structured summaries of current trials, guidelines, and practical management pearls, with a steady emphasis on prep for exams and clinical decision-making. Special features include quick takeaways, exam-friendly mnemonics, and real-world applicability for busy clinicians, fellows, and advanced trainees. Notably, the show consistently pairs two hosts who synthesize complex oncology content into digestible 10–15 minute segments, making it a reliable supplement to more traditional study resources. A distinctive trait is the frequent coverage of emerging therapies and trial data with board-prep framing, plus guest experts who add clinical d... more

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Which podcasts are similar to Two Onc Docs?

These podcasts share a similar audience with Two Onc Docs:

1. ASCO Daily News
2. Oncology Brothers: Practice-Changing Cancer Discussions
3. JAMA Clinical Reviews
4. Core IM | Internal Medicine Podcast
5. The Curbsiders Internal Medicine Podcast

How many episodes of Two Onc Docs are there?

Two Onc Docs launched 4 years ago and published 199 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Two Onc Docs?

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What guests have appeared on Two Onc Docs?

Recent guests on Two Onc Docs include:

1. Dr. Michael Pishvaian
2. Michael Pishvaian
3. Dr. Marc Carrier
4. Marc Carrier
5. Dr. Ria Kraft
6. Dr. Chadi Nabhan
7. Krystle Zuniga
8. Dr. Krystle Zuniga

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