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Two Onc Docs

Sam and Karine
Testicular Cancer
Acute Myeloid Leukemia
Renal Cell Carcinoma
Chemotherapy
Hematopoietic Growth Factors
Semenoma
Immunotherapy
Primary CNS Lymphoma
Melanoma
High-Dose Methotrexate
Elderly Patients
Non-Hodgkin's Lymphoma
Platinum-Based Chemotherapy
Non-Seminoma Germ Cell Tumors
Oncology
Clinical Trials
BRAF MEK Inhibitors
Epidemiology
Cognitive Impairment
Radiation Therapy

This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established... more

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Latest Episodes

We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 3, we discuss supportive care in pancreatic cancer, and e... more

We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 2, we will focus on metastatic pancreatic cancer, 1L trea... more

This week’s episode will be discussing Pancreatic Cancer with a very special guest Dr. Michael Pishvaian. Dr. Pishvaian is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 1,... more

This week’s episode will be focusing on a recap of some of the important data ASCO GU just held in San Francisco end of February. We will go over some topics in prostate, RCC, bladder cancer, and other GU tumors.

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Recent Guests

Michael Pishvaian
Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center; GI oncologist specializing in pancreatic cancer
Johns Hopkins University
Episode: Localized Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 1
Dr. Marc Carrier
Guest expert on thrombosis and cancer
Unknown (presenter)
Episode: Venous Thromboembolism (VTE) in Cancer Part 2
Marc Carrier
Head, Division of Hematology, Ottawa Hospital; Professor and Senior Scientist; expert in venous thromboembolism and cancer
Ottawa Hospital / University of Ottawa
Episode: Venous Thromboembolism (VTE) in Cancer Part 1
Dr. Ria Kraft
A practicing radiation oncologist and YouTuber
Rad Onc Talks
Episode: Rad Onc 101 Part 1
Dr. Chadi Nabhan
Chief Medical Officer of Right AI and host of Healthcare Unfiltered
Right AI
Episode: Why Oncology + Career Pathways in Heme/Onc with Special Guest Dr. Chadi Nabhan
Krystle Zuniga
Board Certified Specialist in Oncology Nutrition
Episode: Oncology Nutrition 101 Part 2
Dr. Krystle Zuniga
Board-certified specialist in oncology nutrition with over 14 years of experience
Episode: Oncology Nutrition 101 Part 1
Dr. Tom Powles
Professor of Oncology at Queen Mary University and director of Barts Cancer Center.
Barts Cancer Center
Episode: Localized Kidney Cancer x Uromigos 2025 UPDATES (Part 1)
Dr. Brian Rini
Chief of Clinical Trials at Vanderbilt Ingram Cancer Center.
Vanderbilt Ingram Cancer Center
Episode: Localized Kidney Cancer x Uromigos 2025 UPDATES (Part 1)

Hosts

Sam
Co-host of the show, focused on hematology/oncology education and board prep.
Karine
Co-host of the show, leads board-review episodes and clinical topic breakdowns.

Reviews

4.8 out of 5 stars from 303 ratings
  • Quick and concise

    I’m an RN in Hematology, and this podcast helped me to pass my OCN exam. The Onc Emergencies and BMT episodes were especially helpful. There is NO FLUFF in here, just quick, quality information So awesome to have an audio resource for multitasking for busy people!

    Apple Podcasts
    5
    Amanda in Utah
    United States4 months ago
  • Exceptional resource for board prep

    This podcast is truly exceptional. I'm immensely grateful for this podcast. Every episode is incredibly high-yield and perfectly tailored for hematology/oncology board prep. I especially loved the concise, easy-to-follow format, which made even the most complex topics feel approachable. It became my constant companion during car rides and treadmill sessions and it genuinely made a huge difference in my exam preparation. Thank you so much for creating such an invaluable resource.

    Apple Podcasts
    5
    ShivaniDalal
    United States4 months ago
  • Great refreshers

    Heme/onc fellow. Love listening to these for a quick refresher or update on high yield points. Or ideas/inspo for chalk talks on rounds. Thanks for the hard work to produce!

    Apple Podcasts
    5
    Sarahh1220
    United States5 months ago
  • The literal best

    Such a great high yield summary of important topics. Sam and Karine are lifesavers for hosting this amazing podcast which came so handy for board prep!

    Apple Podcasts
    5
    whowouldaknown
    United States5 months ago
  • Clear and concise

    Not a doc but an onc pharmacist and this podcast has been my favorite to study to! I love the short, digestible episodes with clear and concise content.

    Apple Podcasts
    5
    yourfavepharmd
    United States7 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests and hosts are viewed as knowledgeable and practical, with strong clinical relevance.
Clear, concise, high-yield board review content loved by trainees.
Listeners praise the bite-sized format for easy on-the-go studying.

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Talking Points

Recent interactions between the hosts and their guests.

Metastatic Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 2
Q: What are the first-line systemic treatment options for metastatic pancreatic cancer?
Frontline regimens include FOLFIRINOX and Nab-paclitaxel (NabPaclitaxel), with Nelliorifox and related regimens offering similar potential benefits; choice depends on performance status, tolerance, and regional practice patterns, with ongoing debate about optimal regimens in different populations.
Metastatic Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 2
Q: What is the treatment if there is local recurrence after surgery in the pancreas or the surgical bed?
If symptomatic, radiation can palliate pain and GI issues; if not symptomatic, treatment decisions follow the approach for metastatic disease, with chemotherapy or targeted therapies depending on patient status and goals.
Venous Thromboembolism (VTE) in Cancer Part 1
Q: Which anticoagulant should be used for initial treatment of a VTE in cancer?
Most patients can start a direct oral anticoagulant such as rivaroxaban or apixaban, with low-molecular-weight heparin as an alternative in certain scenarios.
Venous Thromboembolism (VTE) in Cancer Part 1
Q: What is the workup that you would recommend when you think VTE is suspected in a cancer patient?
Start with ultrasound to diagnose limb DVT if there is swelling; for possible PE, proceed with CT pulmonary angiography or VQ scan due to the elevated thrombotic risk in cancer patients.
Oncology Nutrition 101 Part 1
Q: What should patients know about using supplements during cancer treatment?
Patients should discuss supplements with their healthcare providers, as these products may not be safe, effective, or well-regulated, and can interfere with treatment.

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Frequently Asked Questions About Two Onc Docs

What is Two Onc Docs about and what kind of topics does it cover?

Short, high-yield board review episodes tailored for hematology/oncology trainees and practicing clinicians. Listeners often come for concise clinical pearls, rapid-fire topic breakdowns, and practical guidance useful for exams and real-world patient care. The show frequently covers cancer biology, treatment, supportive care, and emerging therapies, with hosts Sam and Karine delivering tight, exam-focused syntheses and occasional guest insights from leading clinicians and educators. A standout is its strict emphasis on bite-sized, actionable content designed for on-the-go listening, which makes it a reliable supplemental resource for busy healthcare professionals preparing for boards or staying current between calls.

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How many episodes of Two Onc Docs are there?

Two Onc Docs launched 4 years ago and published 191 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Two Onc Docs?

Recent guests on Two Onc Docs include:

1. Michael Pishvaian
2. Dr. Marc Carrier
3. Marc Carrier
4. Dr. Ria Kraft
5. Dr. Chadi Nabhan
6. Krystle Zuniga
7. Dr. Krystle Zuniga
8. Dr. Tom Powles

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