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LifeCode.AI

LotusW

LifeCode.AI是一档关注于AI大模型与生物医疗领域融合发展的播客。我们希望可以帮助大家了解、探索生物医药行业的前沿动态,追踪行业发展,并提供一个分享知识洞见的空间。 每一期我们都会邀请行业专家、科研先锋或者商业领袖,分享他们在AI+生物科技领域的研究成果、商业见解和思考沉淀。 和我们一起,通过对话,打开一个领域的大门。 想了解要更多行业链接?你可以通过下面的方式联系我们 Email:lifecodeai@163.com

PublishesTwice monthlyEpisodes10Foundeda year ago
Language
ZH-CN
Category
Science

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Latest Episodes

本期节目我们邀请了结构生物学专家,目前专注于蛋白设计研究的Alex和生物医药投资资深人士Eric,一起聊聊AI驱动药物发现(AIDD)领域正在发生的变化。

本期你将会听到AIDD公司如何估值、它们的技术壁垒是什么,以及它们的商业模式正在如何转变。我们比较了传统制药和AI平台型公司走的不同路子,聊到了平台技术难以标准化的问题、数据资产怎么挖掘价值,以及从靶点发现到分子设计的验证过程有多复杂。

两位嘉宾还分享了中美AIDD企业的具体案例,讨论了创新药在AI时代如何提升增长预期、降低不确定性的思路... more

从早期的DNA Bert到不久前发布的革命性的模型EVO 2,基因组预测技术在DNA语言模型的加持下不断飞速发展。本期主持人lotus作为嘉宾,与北京大学基因组学方向的博士研究生小蛇一起分享在一线工作中对DNA语言模型的理解。

与传统大语言模型不同,DNA语言模型面临着处理人类基因组长达32亿碱基对这一超长序列的巨大挑战。斯坦福大学和Arc Institute团队的最新研究成果EVO 2模型通过创新的Hyena架构,将上下文窗口扩展到百万级别,将处理小型细菌基因组变为可能。这种架构在序列长度增... more

各位开工大吉!

你是否想过,人体内存在着一个动态更新的"生物密码本"?当免疫细胞通过TCR,BCR受体识别万亿种抗原时,它们正在书写独特的免疫组库——这套精密的防御编码系统,不仅是抵御病原体的终极防线,更隐藏着癌症早期预警的关键信号。

本期是关于免疫组库分享的第二部分,徐博士继续分享了免疫组库为何以及如何在癌症早筛、感染疾病检测环节。初次之外,我们还探讨了单细胞测序和批量次序技术的发展,以及AI如何帮助我们在免疫数据的宝库中找到检测甚至治愈疾病的蛛丝马迹。

【嘉宾介绍】

徐博士,15年前... more

也许我们都知道在自己的身体里有一支精密的"特种部队"——免疫系统,它不仅能识别并消灭入侵的病毒细菌,但你知道吗,这支部队还能通过特定的B细胞和T细胞建立"生物记忆库",帮助你建立固若金汤的生命堡垒。

本期我们邀请到了专注免疫研究的徐博士,他分享了免疫系统的奥秘,以及免疫组库如何在癌症早筛、感染疾病检测和疫苗研发中大显身手。由于时长原因我们会将本次话题分为两期节目,在本期你会听到免疫系统的两大“防线”——先天性免疫和适应性免疫,它们是如何协同工作保护我们的健康。

你也许好奇为什么疫苗能帮助我们... more

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