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抗老工程學

Scott

矽谷工程師 Scott 用第一性原理和工程師的類比,把血糖、膽固醇、脂肪酸、纖維、肌力訓練、皮膚抗老這些長壽科學,一集一個主題講到你徹底聽懂。不灌雞湯、不賣補品,只給你能自己判斷的核心原理。內容改編自粉專「矽谷工程師的抗衰老實驗室」的深度長文。

PublishesWeeklyEpisodes11Founded3 months ago
Language
Chinese (Traditional)
Number of ListenersCategories
MedicineHealth & Fitness

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Latest Episodes

膽固醇系列三集之二·中集(犯罪現場篇),接上集。上集幫膽固醇這個分子平反、也講了把 LDL 降到很低其實是安全的;這集直接進犯罪現場,一步步拆給你看動脈粥狀硬化到底怎麼發生。先搞懂血液的『物流系統』:膽固醇在水裡溶解度極低,要靠脂蛋白這種『貨櫃』運輸;每一顆會闖禍的脂蛋白表面都焊著一個 ApoB-100,像卡車的車牌——所以量 ApoB,等於在數你血裡有幾台卡車。真正滲進血管壁、被滯留、引爆斑塊的顆粒,數量上絕大多數就是 LDL。接著是血管壁裡的五步死亡機制:滲透→滯留(response-to-... more

膽固醇系列三集之一·上集(平反篇)。你是不是也以為膽固醇就是毒素、是心血管的萬惡之源,最好從身體裡清得一乾二淨?這集先幫這個分子平反:膽固醇其實是每一顆細胞都離不開的必需品——是細胞膜的鋼筋、是荷爾蒙與膽汁酸的原料;而且你身上大部分的膽固醇是自己合成的,不是吃進來的,肝臟還有一套精密的負回饋在自動調度。接著逐條破解一個流傳很廣、卻把很多人嚇到不敢吃藥的迷思——「把 LDL 降到很低很危險」:大腦主要靠自己合成膽固醇、不吃血液裡的 LDL;睪固酮主要在性腺就地取材;所謂「LDL 太低會失智、降睪固... more

作者尿酸曾飆到 9.3。這集跟著「一個尿酸分子」走一趟:它怎麼從普林、從果糖生出來(果糖是一腳沒煞車的油門)、人類為什麼在演化上把 uricase 這個酶弄壞、讓血尿酸比狗高上好幾倍(它其實也是人體最主要的抗氧化劑之一);6.8 這條溶解度紅線決定它會不會結晶;為什麼絕大多數的高尿酸其實是『排不掉』而不是『產太多』(URAT1、SLC2A9、ABCG2 這些基因型決定你天生排得快還是慢);作者自己的尿酸結石故事(以及為什麼結石看的是尿液酸鹼、不只是血尿酸);痛風風暴怎麼被 NLRP3 發炎體引爆... more

腸道菌下集(實作篇),接 EP7。你花錢買的益生菌膠囊,對健康人來說,大多幾天就被排掉了——像一批拿觀光簽證的過客。這集講清楚為什麼:你的原生菌群早就把腸道的生態位佔滿了(殖民化抵抗),外來菌很難住下來,所以對健康人日常補充,腸道多樣性和結構往往沒有可測量的改變。那什麼才有用?這集比較「發酵食物 vs 益生菌膠囊」的關鍵差別(發酵食物帶的是一整個生態系+代謝產物,不是單一菌株),講 Stanford 的 Wastyk 2021 Cell 隨機試驗(高發酵食物組菌相多樣性上升、發炎指標下降),並給... more

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Reviews

5.0 out of 5 stars from 255 ratings
  • 好節目 大推!

    好節目 大推!Scott 加油👏

    Apple Podcasts
    5
    SYSCYSC
    United States2 months ago
  • 中年人

    深入淺出 非常推薦

    Apple Podcasts
    5
    Meowbee
    United States2 months ago
  • 推

    長度速度都很剛剛好,內容也很有深度

    Apple Podcasts
    5
    愛咪小猴
    United States2 months ago
  • Hooper

    喜歡用聊天的方式聽你們說專業知識。最後的總結也很棒。

    Apple Podcasts
    5
    mcchiang06
    United States2 months ago
  • 強者我同學

    由淺入深 給博士工程師 無限碎念的空間

    Apple Podcasts
    5
    MrCalf
    United States2 months ago

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2. 聽康健
3. 下一本讀什麼?
4. VK科技閱讀時間
5. 張修修的不正常人類研究所

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抗老工程學 launched 3 months ago and published 11 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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