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Artwork for From First Principles
Cancer Therapy
Supernova
Spintronics
Mars
3I Atlas
NASA
Max Planck Institute
James Webb Space Telescope
Stellar Evolution
Moore's Law
Plastic Recycling
Bee Superfood
No-Sort Plastic
Human Longevity
Analog AI
Earth's Rotation
Baby Solar System
Black Hole Collision
CRISPR Technology
Ancient Inscriptions

We break down the week’s biggest science headlines from first principles—because understanding the world shouldn’t require a PhD.

PublishesTwice weeklyEpisodes21Founded4 months ago
Number of ListenersCategory
Science

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Artwork for From First Principles

Latest Episodes

Hosted by Lester Nare and Krishna Choudhary, this single-story deep dive tells the full story of how humanity uncovered the structure of DNA — and the human tensions that shaped it. From Mendel’s pea-plant mathematics to Rosalind Franklin’s groundbre... more

YouTube

Hosted by Lester Nare and Krishna Choudhary, this episode spans astrophysics, forensic chemistry, and neuroimmunology. We begin with a deep dive into 3I/ATLAS, only the third confirmed interstellar object to ever pass through our solar system — large... more

YouTube

Hosted by Lester Nare and Krishna Choudhary, this episode dives into three breakthroughs stretching across aerospace engineering, astrobiology, and quantum computing. We start with a Nature Communications paper from Stevens Institute that experimenta... more

YouTube

Hosted by Lester Nare and Krishna Choudhary, this super-episode spans four wildly different frontiers: bioengineers hijacking bacterial evolution to mass-produce octopus camouflage pigment; orcas developing cultural hunting strategies against great w... more

YouTube

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Hosts

Lester Nare
Co-host and Captain, known for breaking down complex scientific topics into accessible discussions.
Krishna Choudhary
Co-host and Resident PhD, dedicated to making science approachable for all.

Reviews

5.0 out of 5 stars from 61 ratings
  • Scientifically awesome

    What a podcast! Science can be interesting and useful, and these guys do an amazing job of explaining that concept.

    Apple Podcasts
    5
    Diogenesofsinop
    United States2 months ago
  • Great podcast

    The content of the show is GREAT A+. Please work on the thumping sound from one or both of the microphones and adjust the volume so both hosts are more balanced. Everyone interested in current science trends and topics should give this show a listen.

    Apple Podcasts
    4
    AtcNickel
    United States2 months ago
  • In depth, but not intimidating

    These guys go in depth with the science, but they hold your hand with the background. You come away actually understanding what happened. They’re also funny. Easy 5 star, would recommend.

    Apple Podcasts
    5
    Kmoney314159
    United States3 months ago
  • Loved this.

    Was recommended this channel and absolutely loved the information and how directive it was. Anyone new please check all of them out. 5 star review easily! -shafer

    Apple Podcasts
    5
    ShaferGMoney
    United States3 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Feedback indicates a desire for improved audio quality, though the content's value outweighs technical issues.
Reviews praise the hosts for combining in-depth discussions with humor, making science accessible to everyone.
Listeners highlight the podcast's ability to make complex scientific topics understandable.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#109
United States/Science
Apple Podcasts
#53
Canada/Science
Apple Podcasts
#150
United Kingdom/Science
Apple Podcasts
#117
Australia/Science
Apple Podcasts
#171
France/Science
Apple Podcasts
#56
India/Science

Talking Points

Recent interactions between the hosts and their guests.

FFP EP. 11 | From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked
Q: What does peripheral immune tolerance mean?
It is the mechanism that prevents our immune system from attacking our own body tissues.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
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Social Media Reach

Frequently Asked Questions About From First Principles

What is From First Principles about and what kind of topics does it cover?

The content is centered around breaking down complex scientific concepts and current science headlines, making them accessible and engaging for a broad audience. Topics frequently covered include advancements in technology, explorations of natural phenomena, and discussions about significant scientific achievements, such as Nobel Prize discoveries and emerging research in various fields of science. The dynamic between the hosts adds a unique flavor, combining humor with insightful commentary, which helps demystify challenging subjects for listeners without a scientific background. Emphasizing clear explanations, the podcast provides a platform for listeners to stay informed about the latest developments in the science world while enhancing ... more

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Which podcasts are similar to From First Principles?

These podcasts share a similar audience with From First Principles:

1. What Trump Can Teach Us About Con Law
2. Common Sense with Dan Carlin
3. Freakonomics Radio
4. 99% Invisible
5. Dan Carlin's Hardcore History: Addendum

How many episodes of From First Principles are there?

From First Principles launched 4 months ago and published 21 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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