Rephonic
Artwork for Free Radicals
Aging
Longevity
Biotechnology
Epigenetic Reprogramming
Healthspan
Cell Therapy
Biotech
CRISPR
Dr. Alex Colville
Stanford University
Artificial Intelligence
Il-11
Tissue Engineering
Longevity Biotech Fellowship
DNA Damage
Calico
Impetus Grants
Drug Discovery
Sirna
Polyphron

Interviewing visionaries dedicated to giving humanity control over biology. All problems are solvable, including aging and death.

PublishesWeeklyEpisodes27Founded9 months ago
Number of ListenersCategories
Life SciencesScience

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Artwork for Free Radicals

Latest Episodes

Reprogramming molecules are getting dosed into patients for the first time, with the goal of restoring function lost due to aging. I‘ve had over 30 recorded conversations about the longevity space and didn’t realize this is happening so soon!

We sat... more

AI is accelerating the pace of progress for benevolent scientists and nefarious actors alike. We discuss how DARPA is preparing to defend agriculture & civilians from novel biological threats, and why such defense requires training foundation models ... more

Kris Borer is an entrepreneur, angel investor, and author of the new book Radical Life Extension.

We discuss why Kris rejects incrementalist approaches to radical life extension, and his argument that supplement, lifestyle interventions and small-mo... more

Jonathan Anomaly is a co-founder of Herasight and former PPE professor. Herasight is pioneering polygenic screening for embryos, to help parents undergoing IVF select embryos for health, intelligence, height, and other traits people care about.

We d... more

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Recent Guests

Jamie Justice
Head of XPRIZE Healthspan
XPRIZE Healthspan
Episode: The $101M XPRIZE to restore function by 10 - 20 years - Jamie Justice
Michael Koeris
Director of DARPA's Biological Technologies Office
DARPA
Episode: How DARPA prepares for AI-designed bioweapons & is accelerating progress towards longevity biotech - Dr. Mike Koeris, DARPA Director
Kris Borer
Author of Radical Life Extension, entrepreneur, longevity investor
Author & Investor, Radical Life Extension
Episode: Replacement & Biostasis: radical approaches for solving aging - Kris Borer, Author & Investor
Jonathan Anomaly
Founder/CEO of Herasight, biologist-focused entrepreneur
Herasight
Episode: Selecting the Superman? Embyro selection with Jonathan Anomaly
Simon Kohl
Latent Labs founder and CEO; former DeepMind researcher on the AlphaFold 2 team
Latent Labs
Episode: The future of AI-powered personalized drugs is only a few years away - Latent Labs founder Simon Kohl
Elliot Hershberg
Partner at Amplify Partners; author of Century of Biology
Amplify Partners
Episode: How GLP-1s are paving the way for the new era of biotech - Elliot Hershberg, Investor & Blogger
James Peyer
Founder and CEO of Cambrian Bio
Cambrian Bio
Episode: There are no longevity drugs today, but there will be soon - Dr. James Peyer, Cambrian Founder
Nathan Cheng
Longevity activist and founder involved in Longevity Biotech Fellowship and Vitalism Foundation
Longevity Movement
Episode: Aging kills EVERYONE, but only because we're not trying hard enough - Longevity Activist Nathan Cheng
Kexin Huang
Founder/CEO of Phylo
Phylo
Episode: The one-man biotech is only 10 years away - a16z-backed founder Kexin Huang

Hosts

Daniel Schurr
Host of the Free Radicals program
Eric Dai
Co-host of the Free Radicals program

Reviews

5.0 out of 5 stars from 36 ratings
  • Though Provoking Topics

    Big fan of this pod. Hosts are seriously smart and know their stuff. Love the optimism about the future and what technology can unlock for humanity

    Apple Podcasts
    5
    m0d3rate
    United States2 months ago
  • Very high signal

    The hosts do a lot of research and ask great questions. Excellent lineup of guests too. Taking a lot of notes!

    Apple Podcasts
    5
    BCBC DNG
    United States7 months ago
  • A must listen

    These guys are seriously smart, ask great questions, and pick excellent guests. Also just a great dose of optimism in an often cloudy world— highly recommend!!

    Apple Podcasts
    5
    Shhhgnkuev
    United States8 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High-quality questions and research-driven conversations.
Notable for optimism about technology and humanity.
Smart hosts with deep preparation and strong guest lineups.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

How DARPA prepares for AI-designed bioweapons & is accelerating progress towards longevity biotech - Dr. Mike Koeris, DARPA Director
Q: How does DARPA interact with other agencies to facilitate regulatory and manufacturing advances for these programs?
DARPA works with the DOD, FDA, HHS, USDA, and other agencies on priority lists (MIPL) to ensure priority reviews and align civilian and military needs, while pursuing onshore biomanufacturing and modular manufacturing approaches to accelerate and de-risk translation.
How DARPA prepares for AI-designed bioweapons & is accelerating progress towards longevity biotech - Dr. Mike Koeris, DARPA Director
Q: What are some of the macro trends in medicine and military medicine that DARPA is pursuing now?
Key focus areas include combat casualty care innovations like universal or shelf-stable blood, autonomy and AI for performance, cognitive and physical enhancements, brain–computer interfaces (prefer non‑invasive for scalability), and synthetic biology approaches that could transform how we think about drugs, diagnostics, and manufacturing.
How DARPA prepares for AI-designed bioweapons & is accelerating progress towards longevity biotech - Dr. Mike Koeris, DARPA Director
Q: Could you maybe give us a broad view of how you picture the sci‑fi future at DARPA?
The mission is to prevent and create strategic surprise using technology by pulling forward near‑term progress on ideas that sit 2–5 years out, while keeping a long horizon for identifying which technologies to advance into the near future.
There are no longevity drugs today, but there will be soon - Dr. James Peyer, Cambrian Founder
Q: How do you view the role of GLP-1s in longevity vs. aging biology?
GLP-1s are powerful for obesity and metabolic diseases but do not inherently address core aging biology; they may serve as a gateway to prevention but are not a true gerotherapeutic by themselves. The field seeks drugs that target fundamental aging processes to improve healthspan beyond what obesity-focused therapies can achieve.
There are no longevity drugs today, but there will be soon - Dr. James Peyer, Cambrian Founder
Q: What is ATX304 and why is it significant in Cambrian's work?
ATX304 is the first direct activator of AMPK to enter human trials, with preclinical data suggesting it can reset metabolic aging in animals and improve metabolic health, potentially reversing aspects of aging-related decline and preventing multiple diseases.

Audience Metrics

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Frequently Asked Questions About Free Radicals

What is Free Radicals about and what kind of topics does it cover?

Listeners engage with high-signal discussions at the intersection of biology, technology, and longevity. Episodes frequently explore aging, longevity interventions, biotech startup dynamics, AI-assisted biology, and policy or regulatory implications, often through interviews with researchers, founders, funders, and policymakers. The show tends to blend rigorous scientific framing with practical industry insights, spotlighting new platforms, clinical translation challenges, and ambitious visions for extending healthy lifespans. A notable strength is the breadth of guest backgrounds—from academia and government programs to venture-backed biotech and AI-enabled biology—delivering both technical depth and strategic perspective for listeners bui... more

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These podcasts share a similar audience with Free Radicals:

1. Moonshots with Peter Diamandis
2. Dwarkesh Podcast
3. The a16z Show
4. The Tim Ferriss Show
5. Lifespan with Dr. David Sinclair

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Free Radicals launched 9 months ago and published 27 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Free Radicals?

Recent guests on Free Radicals include:

1. Jamie Justice
2. Michael Koeris
3. Kris Borer
4. Jonathan Anomaly
5. Simon Kohl
6. Elliot Hershberg
7. James Peyer
8. Nathan Cheng

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