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分子デザインはじめました

分子デザインはじめました

このpodcastは、さまざまな形で分子デザインに携わるメンバーが分子デザインについてゆるく語りつつ情報発信する番組です。タンパク質デザインや核酸 (DNA/RNA)デザインが主なトピックです。X: twitter.com/Biomol_Design

PublishesInfrequentlyEpisodes27Founded17 days ago
Language
Japanese
Categories
Life SciencesScience

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Artwork for 分子デザインはじめました

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Ep 20-1 ラボミーティングでたこ焼き作る話https://open.spotify.com/episode/7jpHi8W1eNAoMtQz9GwY44

紹介した論文

[0:16:36–] 新津

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南慎太郎さん x.com/shintaro_minami

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岡本紹介論文一本目

Connecting chemical and protein sequence space to predict biocatalytic reactions

doi.org/10.1038/s41586-025-09519-5

岡本紹介論文二本目

De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis

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岡本紹介論文一本目

Connecting chemical and protein sequence space to predict biocatalytic reactions

doi.org/10.1038/s41586-025-09519-5

岡本紹介論文二本目

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理化学研究所 生命医科学研究センター 高機能生体分子開発チーム

Design of facilitated dissociation enables timing of cytokine signalling

Dr. Adam Broerman

Dr. Florian Praetorius

エフェクター結合でターゲットを解離させる (koffを上げる)メカニズムはkick outで正しい。エフェクターがinduced-fitすることでパワーストロークを起こし、ターゲットをkick ou... more

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