
このpodcastは、さまざまな形で分子デザインに携わるメンバーが分子デザインについてゆるく語りつつ情報発信する番組です。タンパク質デザインや核酸 (DNA/RNA)デザインが主なトピックです。X: twitter.com/Biomol_Design
| Publishes | Infrequently | Episodes | 27 | Founded | 17 days ago |
|---|---|---|---|---|---|
| Language | Categories | Life SciencesScience | |||

Chapter
(0:00:00) 祝ポッドキャスト2周年!
(0:01:50) 浜田さん論文1(DNAハイドロゲル)
(0:16:00) Wet Lab Tips 1(キャピラリー粘度測定・Echo分注機)
(0:20:17) 浜田さん論文2(動的DNAネットワーク)
(0:32:10) DiffusionモデルでDNAオリガミ論文
(0:40:37) Wet Lab Tips 2(ピペット、培養、クローニング)
(1:00:03) Claude
(1:10:32... more
Ep 24: Membrane Protein Design Journal Club
Ep 20-1 ラボミーティングでたこ焼き作る話https://open.spotify.com/episode/7jpHi8W1eNAoMtQz9GwY44
紹介した論文
[0:16:36–] 新津
Deep learning-based joint sequence–structure de novo membrane protein design
Rudden et al., bioRxiv more
・寺坂尚紘先生
nterasaka.wixsite.com/terasaka-lab
・Science Tokyo ELSI
・MULTI-evolve
・Ref: EVOLVEpro
・PLACER
github.com/baker-laboratory/PLACER
www.pnas.org/doi/10.1073/pnas.2427161122
・Claude
・... more
ゲスト:金森崇さん
ジーンフロンティア株式会社基盤技術開発部 部長ジーンフロンティア
PURE frex
www.genefrontier.com/solutions/purefrex/
PURE system の論文
Cell-free translation reconstituted with purified components.
Y. Shimizu et al., Nat. Biotechn... more
生体分子設計研究会 2025/12/10
BindCraft
* 論文
* GitHub
* Google Colab
BoltzGen
* プレプリント
* GitHub
南慎太郎さん x.com/shintaro_minami
森脇さん x.com/Ag_smith
GeneScript人工遺伝子合成
IDT eBlock, gBlock
Foldseek (構造ベースのクラスタリングに便利):
Mmseq2 (配列ベースの... more
岡本紹介論文一本目
Connecting chemical and protein sequence space to predict biocatalytic reactions
doi.org/10.1038/s41586-025-09519-5
岡本紹介論文二本目
De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis
doi... more
岡本紹介論文一本目
Connecting chemical and protein sequence space to predict biocatalytic reactions
doi.org/10.1038/s41586-025-09519-5
岡本紹介論文二本目
De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis
doi... more
理化学研究所 生命医科学研究センター 高機能生体分子開発チーム
Design of facilitated dissociation enables timing of cytokine signalling
Dr. Adam Broerman
Dr. Florian Praetorius
エフェクター結合でターゲットを解離させる (koffを上げる)メカニズムはkick outで正しい。エフェクターがinduced-fitすることでパワーストロークを起こし、ターゲットをkick ou... more
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #41 |









Listeners, social reach, demographics and more for this podcast.
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