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Artwork for EHA Unplugged
Hematology
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Clinical Trials
Artificial Intelligence
CAR T Cell Therapy
Immunotherapy
Chronic Lymphocytic Leukemia
TP53 Mutations
Synthetic Data
AML
Young EHA
Europe
High-Risk MDS
Hypomethylating Agents
Iron Metabolism
Sickle Cell Disease
European Hematology Association
IDH Inhibitors
Genetic Testing

In these EHA-produced podcasts, experts share with you their hematology knowledge and stories. With "EHA Unplugged" we would like to give you the opportunity to unplug from your computer screen, while still learning, by listening to interviews, clinical cases, monologues, and more.

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Artwork for EHA Unplugged

Latest Episodes

In this episode, EHA 2026 Lifetime Achievement Award recipient Prof Claire Harrison reflects on a career dedicated to advancing the understanding and management of myeloproliferative neoplasms (MPNs). She reviews the major scientific and clinical dev... more

In this episode, Dr Annalisa Ruggeri discusses how registry data are helping clinicians better understand, monitor and manage CAR T-related toxicities. She explains how insights from more than 16,000 patients recorded in the European Bone Marrow Tran... more

YouTube

In the final episode of our mini-series celebrating the 10th anniversary of the Young EHA Research Meeting (YERM), we explore how the meeting acts as a powerful launching pad for scientific careers. We talk to 2018 YERM speakers Dr. Lorena Arranz and... more

YouTube

Welcome to our mini-series celebrating the 10th anniversary of the Young EHA Research Meeting (YERM) with an introduction to its history and mission. We sit down with co-founder Prof Ruud Delwel and current organizer Prof Marlies Vanden Bempt to disc... more

YouTube

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Recent Guests

Mattias Carlsten
Consultant hematologist; head of research development and education at the cell therapy and allotransplant unit, Karolinska University Hospital
Karolinska University Hospital; Karolinska Institute
Episode: Life After YERM: How the Young EHA Research Meeting Shaped Careers
Lorena Arranz
Associate professor; leads stem cells aging and cancer research; deputy director of a Norwegian Center of Excellence
University of Oslo; Oslo University Hospital
Episode: Life After YERM: How the Young EHA Research Meeting Shaped Careers
Marlies Vanden Bempt
Junior group leader at KU Leuven; Young EHA committee member since 2024
KU Leuven
Episode: Discover YERM: The Young EHA Research Meeting and Your Place in It
Ruud Delwel
Molecular biologist; professor of molecular leukaemogenesis
Erasmus University Medical Center
Episode: Discover YERM: The Young EHA Research Meeting and Your Place in It
André Baruchel
Professor of Pediatrics at Université Paris-Cité and former head of Pediatric Hematology Immunology at Hôpital Robert-Debré, Paris
Université Paris-Cité / Hôpital Robert-Debré
Episode: CAR-T for Pediatric B-ALL: Expert Tips
Marion Subklewe
Hematologist oncologist specializing in cellular immunotherapy
LMU Munich, Germany
Episode: Getting Patients to CAR T: Referral Systems in Europe
Dr. Alexandra Martínez Roca
Hematologist at Hospital Clínic de Barcelona, Atom Unit
Hospital Clínic de Barcelona
Episode: Outpatient CAR T in Europe: Lessons from Barcelona
Dr. Beatriz Merchán Muñoz
Hematologist specializing in advanced therapies at home
Atom Unit, Barcelona
Episode: Outpatient CAR T in Europe: Lessons from Barcelona
Andrea Schmidts
Emmy Noether group leader and principal investigator in Medicine 3 Hematology-Oncology at the Technical University of Munich
Technical University of Munich
Episode: Smarter CARs: Using AI to Improve Chimeric Antigen Receptor Design

Host

Isabel Olivera
Host of EHA Unplugged

Reviews

4.8 out of 5 stars from 25 ratings
  • EHA unplugged

    Great to hear Professor McCann again and fantastic that EHA podcasts are once again back on iTunes Store for ease of access.

    Apple Podcasts
    5
    Doctor Soapie
    United Kingdom5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Great to hear Professor McCann again and fantastic that EHA podcasts are once again back on iTunes Store.
Audience appreciates high-quality clinicians and researchers sharing practical insights.
Listeners value the European perspective and guideline-context discussions.

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Talking Points

Recent interactions between the hosts and their guests.

CAR-T for Pediatric B-ALL: Expert Tips
Q: In which scenarios should CAR-T be used in pediatric B-ALL and how should referrals be prioritized?
CAR-T is most clearly indicated in advanced, relapsed or refractory disease, with ongoing exploration of first-relapse scenarios and potential future use in select very high-risk first-line cases; decisions are guided by prior treatments, transplant history, and evolving trial data.
Discover YERM: The Young EHA Research Meeting and Your Place in It
Q: What have been some memorable moments or turning points for YERM?
Memorable moments include the inaugural Madrid edition that proved the concept could work, the shift to online organization during COVID, and the increasing emphasis on accessible, engaging keynote talks that appeal to people from diverse backgrounds within hematology.
Smarter CARs: Using AI to Improve Chimeric Antigen Receptor Design
Q: For someone new to AI using this, do you have any tips?
Start with de novo designed protein binders and proof of concept data, acknowledge the steep learning curve, and plan for a multi-layer process where design scales rapidly but experimental validation remains the bottleneck; develop strategies for high-throughput screening to efficiently vet hundreds to thousands of candidates.
Smarter CARs: Using AI to Improve Chimeric Antigen Receptor Design
Q: What aspects of the CAR did your AI system design or optimize?
The pipeline currently focuses on designing and optimizing the binding domain that mediates target binding, with the AI generating structure-guided binders that are later translated into amino acid sequences and integrated into the CAR, while other groups may use AI for manufacturing or other design aspects.
Smarter CARs: Using AI to Improve Chimeric Antigen Receptor Design
Q: How have researchers historically designed CARs?
Historically, researchers borrowed from existing monoclonal antibodies to build the binding domain, using prior clinical-grade antibodies and experience with antibodies to inform CAR construction, with a focus on adapting these components into the CAR architecture.

Audience Metrics

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Frequently Asked Questions About EHA Unplugged

What is EHA Unplugged about and what kind of topics does it cover?

The show centers on hematology, featuring expert clinicians, researchers, and patient advocates who discuss cutting-edge therapies, guidelines, and real-world practice across Europe and beyond. Recent episodes cover immunotherapies in multiple myeloma, new targeted approaches in AML, HIV-associated and large B-cell lymphomas, and the evolving role of CAR-T and bispecifics, along with practical considerations like toxicity management, trial design, and access to therapies. A recurring strength is translating complex science into clinical practice and policy context, with guests often sharing career journeys, mentorship, and the dynamics of interdisciplinary collaboration. Noteworthy is the emphasis on guideline development, international tri... more

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Which podcasts are similar to EHA Unplugged?

These podcasts share a similar audience with EHA Unplugged:

1. VJHemOnc Podcast
2. Blood Podcast
3. Blood Cancer Talks
4. HemeTalks: Conversations in Hematology Education
5. NEJM This Week

How many episodes of EHA Unplugged are there?

EHA Unplugged launched 5 years ago and published 195 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on EHA Unplugged?

Recent guests on EHA Unplugged include:

1. Mattias Carlsten
2. Lorena Arranz
3. Marlies Vanden Bempt
4. Ruud Delwel
5. André Baruchel
6. Marion Subklewe
7. Dr. Alexandra Martínez Roca
8. Dr. Beatriz Merchán Muñoz

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