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Artwork for Dr. Matt and Dr. Mike's Medical Podcast

Dr. Matt and Dr. Mike's Medical Podcast

Dr Mike Todorovic
Metabolism
Exercise Physiology
Cardiovascular System
Cranial Nerves
Hypertension
Insulin
Inflammation
Nsaids
Blood Pressure
Physiology
Aspirin
B Vitamins
Proteins
Anabolic Steroids
Christmas
Testosterone
Respiratory System
Amnion
Heart
Paracetamol

Join Dr Matt and Dr Mike, University Professors of Anatomy and Physiology, on their journey through the human body!

Hosted on Acast. See acast.com/privacy for more information.

PublishesWeeklyEpisodes294Founded9 years ago
Number of ListenersCategories
MedicineHealth & FitnessScience

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Artwork for Dr. Matt and Dr. Mike's Medical Podcast

Latest Episodes

What is the pathogenesis and pathophysiology of chronic kidney disease?!

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How vitamins function as coenzymes, what makes the GLUT transporters different, how ADH and aldosterone defend blood volume after fluid loss, and what separates type 1 from type 2 respiratory failure, and more!!... 

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What drugs agonise and antagonise the sympathetic and parasympathetic nervous system?

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*This content is for educational purposes only and does not constitute medical advice.

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Key Facts

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Recent Guests

Boba Fett
Renowned bounty hunter invited on the show as a guest
Star Wars universe
Episode: Introduction to Antibiotics
Jake Paul
Boxing sensation and YouTube personality
Episode: Q&A #12 | DOMS, bone growth, how Dr Matt & Dr Mike met, and more...
Heather Graham
Movie star, known for roles in Boogie Nights and The Hangover
Episode: Lactic acid is a lie
Will Wheaton
Child actor known for his role in Star Trek
Episode: Exercise Physiology | Muscle (Part 7)
Mr. Peter Dutton
Leader of the opposition, head of the LNP
Liberal Party, Australia
Episode: Exercise Physiology | Exercise and the Immune System (Part 5)
Una Chaplin
Host of a new podcast called Hollywood Exiles
CBC Podcasts and BBC World Service
Episode: Aminopeptidase | A-Z of the Human Body

Hosts

Dr. Michael Todorovitch
Host of the show, university professor of anatomy and physiology; active educator and medical educator.
Dr. Matthew Barton
Co-host who asks questions and explains concepts; frequent contributor.

Reviews

4.9 out of 5 stars from 3k ratings
  • The Pitt Explained

    I just listened to episode 1 of The Pitt. It was excellent! This podcast is a brilliant way to help us better understand what’s going on medically throughout the series. Seems like making this show would be a lot of work for you both, but it’s much appreciated by this RN 😊

    Apple Podcasts
    5
    Awesometrix
    United States4 months ago
  • Just Ignore the Boring People Comments.

    I have a background in the medical field, I think it’s great fun that you can take these involved, often dry medical topics and still include humor and banter. This is educational and entertaining. For the folks that can’t take a joke, and would like to cut the banter, there are plenty of dry textbooks that would thrill you to pieces. I will continue to enjoy this podcast. History, science and humor. You guys are great, keep up the good work!

    Apple Podcasts
    5
    HereComesTheSun1215
    United States4 months ago
  • Informative and fun

    Thank you both for all of your hard work in producing such an entertaining, interesting, and informative podcast. Please ignore any haters and continue with the banter and chat! Jt makes learning way more fun, you’ve been a lifesaver for my anaesthesia exams 🙏 Please keep doing what you’re doing!

    Apple Podcasts
    5
    Sophie mpt
    United Kingdom4 months ago
  • For the Data-Driven and Curious

    These hosts are exceptional. I’m simply a health-conscious autodidact and technologist by trade - no exams to pass and no formal medical training required. I listen for the depth of science.

    I probably grasp about 70% of the material, but even that provides meaningful insight into my own health. This isn’t medical advice - it’s medical education.

    The content is academically precise yet approachable and comprehensive. The interaction between Dr. Mike and Dr. Matt feels genuine and conversationa... more

    Apple Podcasts
    5
    RowboTony
    United States6 months ago
  • Passed my emergency and critical care boards!

    I just passed my veterinary emergency and critical care board exam and I have to give a huge thank you to Dr. Matt and Dr. Mike for their help. Listening to their amazing podcast and watching their YouTube make the information I was learning click in a meaningful way. THANK YOU!!

    Apple Podcasts
    5
    Raquibelle
    United States10 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Audience highlights usefulness for exams and clinical understanding; humor is appreciated.
Listeners praise depth and accessibility, with many noting how banter makes complex topics memorable.
Some callers mention wanting more focused episodes without banter, but overall feedback remains highly positive.
High value placed on clear explanations and practical takeaways for medical education.
Listeners appreciate the mix of basic and advanced content and the YouTube integration as study aids.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Q&A #14 | RAAS & Blood Pressure, Bone Cells, GFR, Mechanism of SSRIs, Adaptive Immune System, and more!
Q: How do changes in fluid dynamics and capillary permeability lead to edema in sepsis and heart failure?
Edema arises when capillary hydrostatic pressure increases or oncotic pressure decreases, causing net outward fluid movement. In heart failure, venous congestion raises capillary pressure; in sepsis, inflammatory mediators increase capillary permeability, allowing plasma proteins to leak into tissue and draw fluid out, leading to interstitial edema and, in severe cases, organ dysfunction.
Q&A #14 | RAAS & Blood Pressure, Bone Cells, GFR, Mechanism of SSRIs, Adaptive Immune System, and more!
Q: What is GFR and why is it important?
GFR is the estimated rate at which the kidneys filter blood per minute, usually expressed in mL/min/1.73 m². It reflects overall kidney function and is calculated using age, sex, height, weight, and serum creatinine. Values guide staging of CKD and inform management decisions.
Q&A #13 | Viruses Hijacking Glycolysis, Menopause & Hot Flashes, and Insulin Resistance
Q: Catherine asked about vasomotor symptoms during menopause and the role of KNDY neurons in the arcuate nucleus.
KNDY neurons produce kisspeptin, neurokinin B, and dynorphin, modulating pulsatile GnRH release; reduced estrogen during menopause removes inhibitory feedback, leading to hyperactivity of these neurons and triggering thermoregulatory responses causing hot flashes.
Q&A #13 | Viruses Hijacking Glycolysis, Menopause & Hot Flashes, and Insulin Resistance
Q: From Joseph in England, what does it mean that viruses hijack glycolysis, and which viruses do this?
Viruses can stimulate host glycolysis to provide energy and biosynthetic precursors for viral replication; examples include human cytomegalovirus, Influenza A, SARS-CoV-2, and Dengue virus, which activate pathways to favor an anabolic metabolic state.
Q&A #13 | Viruses Hijacking Glycolysis, Menopause & Hot Flashes, and Insulin Resistance
Q: Chelsea asked, how does insulin resistance work, and what are the broad roles of insulin in the body?
Insulin promotes glucose uptake in muscle and fat, suppresses hepatic glucose output, supports glycogen synthesis, and promotes lipogenesis while suppressing lipolysis; when resistance develops, tissues respond less, leading to higher blood glucose, increased gluconeogenesis, and more fatty acids in circulation.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Dr. Matt and Dr. Mike's Medical Podcast

What is Dr. Matt and Dr. Mike's Medical Podcast about and what kind of topics does it cover?

Two physician-hosts with teaching-heavy, Q&A driven conversations cover human physiology, anatomy, pharmacology, and clinical reasoning. Episodes blend clear explanations of key mechanisms (renal function, glucose transport, cardiac physiology, antibiotics, GLP-1 therapies) with practical clinical contexts, study tips, and light banter. The format frequently features student and professional listeners asking questions, which keeps content approachable for learners while still offering depth for Practitioners. A notable strength is the approachable pedagogy—concepts are broken down with analogies, real-world examples, and exam/review relevance—making it appealing to students, healthcare professionals, and curious general audiences alike.

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Which podcasts are similar to Dr. Matt and Dr. Mike's Medical Podcast?

These podcasts share a similar audience with Dr. Matt and Dr. Mike's Medical Podcast:

1. Ninja Nerd
2. Zero to Finals Medical Revision Podcast
3. Anatomy and Physiology - Bit by Bit
4. Straight A Nursing: Study for nursing school exams & NCLEX
5. Real Life Pharmacology - Pharmacology Education for Health Care Professionals

How many episodes of Dr. Matt and Dr. Mike's Medical Podcast are there?

Dr. Matt and Dr. Mike's Medical Podcast launched 9 years ago and published 294 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Dr. Matt and Dr. Mike's Medical Podcast?

Recent guests on Dr. Matt and Dr. Mike's Medical Podcast include:

1. Boba Fett
2. Jake Paul
3. Heather Graham
4. Will Wheaton
5. Mr. Peter Dutton
6. Una Chaplin

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