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Critical Matters

Sound Physicians
Critical Care Medicine
Intensive Care Medicine
Sepsis
Mechanical Circulatory Support
Critical Care
Clinical Guidelines
Cardiogenic Shock
Cardiac Arrest
Intravenous Albumin
Life-Threatening Asthma
Acute Kidney Injury
Acute Aortic Dissection
Emergency Medicine
Seizures
Intensive Care Unit
Artificial Intelligence
Fluid Overload
Congenital Heart Disease
Patient Safety
Post-Cardiac Arrest

Podcast by Sound Physicians

PublishesTwice monthlyEpisodes174Founded9 years ago
Number of ListenersCategory
Science

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Artwork for Critical Matters

Latest Episodes

In a recent episode, Dr. Sergio Zanotti discussed the 2026 iteration of the Surviving Sepsis Guidelines. In this episode, the discussion continues, focusing on important aspects beyond clinical guidelines. He is joined by Dr. Andre Kalil, a physician... more

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This episode was originally posted Feb. 24, 2022.

The last 24 months have pushed ICU teams around the world to their limits. As we move forward, we need to heal and rebuild our critical care teams. Healthcare more than ever will require ICU teams to... more

YouTube

In this episode, Dr. Sergio Zanotti discusses the care of older adults in the ICU. He is joined by Dr. Lauren Ferrante, a pulmonary critical care physician in the medical intensive care unit at Yale New Haven Hospital. She is an Associate Professor o... more

YouTube

In this episode, Dr. Sergio Zanotti discusses arterial catheters in shock through the lens of the recently published EVERDAC trial. He is joined by Dr. Gregoire Muller, a critical care physician in the Department of Intensive Care Medicine and Resusc... more

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Recent Guests

Lauren Ferrante
Pulmonary Critical Care physician; Yale New Haven Hospital
Yale New Haven Hospital, Yale School of Medicine
Episode: Caring for older adults in the ICU
Grégoire Muller
Critical Care Physician
University Hospital Center of Orléans, Orléans, France
Episode: Rethinking arterial lines
Max Adelman
Practicing critical care and infectious disease physician; assistant professor of medicine
Houston Methodist Hospital; Weill Cornell Medical College
Episode: Invasive Candidiasis
Dr. Hallie Prescott
Associate Professor in Pulmonary and Critical Care Medicine at the University of Michigan; staff physician at the Ann Arbor VA Healthcare System; co-chair of the International Surviving Sepsis Campaign Guidelines
University of Michigan; Ann Arbor VA Healthcare System
Episode: Surviving sepsis campaign 2026 guidelines
Dr. Bram Rochwerg
Associate Professor and Critical Care Physician at McMaster University; Associate Editor at Critical Care Medicine; co-vice chair of the Surviving Sepsis Campaign Adult Guidelines
McMaster University
Episode: Surviving sepsis campaign 2026 guidelines
Waqas Akhtar
Consultant at Guy's & St Thomas' NHS Foundation Trust, lead author of UK Multisociety Consensus Statement on Emergency Management of Left-Sided Impella
Guy's & St Thomas' NHS Foundation Trust
Episode: Management of Impella Emergencies
Vasileios Panoulas
Consultant cardiologist at Royal Brompton & Harefield NHS Trust; honorary senior clinical lecturer at Imperial College London
Royal Brompton & Harefield NHS Trust
Episode: Management of Impella Emergencies
Mark Creager
Lead author and chair of the writing committee for the guidelines
Geisel School of Medicine / Dartmouth-Hitchcock Medical Center
Episode: Acute Pulmonary Embolism: Clinical Guideline Update
Dr. Waqas Akhtar
Consultant at Guy's & St Thomas' NHS Foundation Trust in the UK.
Guy's & St Thomas' NHS Foundation Trust
Episode: ECMO Emergencies

Host

Dr. Sergio Zanotti
Host with expertise in critical care topics and clinical guidelines

Reviews

5.0 out of 5 stars from 39 ratings
  • Favorite Podcast

    This has become one of my favorite podcasts. I like the format. The quality of guests on is A1. No nonsense high yield. Amazing

    Apple Podcasts
    5
    KalyanKosuri
    United States6 months ago
  • Great discussions for all ICU team members!

    I love this podcast! I am a first year I see you attending, and I have the privilege of working in a very busy hospital with surgical, medical, transplant, cardiology, and a new ICU. This podcast really reinforces concepts and cutting edge things in our field. the only gripe i have is that the volume levels are all over the place! Sometimes everything is super soft and I had to turn the volume up. Then the next sentence is blasting in my ear. I wish whoever their sound editor was was able to le... more

    Apple Podcasts
    4
    sram730
    United States4 years ago
  • Best podcast on Critical Care related matters

    I’m a critical care fellow in South Africa and am currently preparing for my final exam coming up in 4 months. I’ve only recently discovered this podcast after struggling through a few others.

    I found Critical Matters easy to listen to, highly relevant and current. It feels like one of our Journal Clubs combined with an ISICEM-like feel to the high standard of expertise being shared.

    Thank you so much!

    Apple Podcasts
    5
    Christel_ArnoldDay
    South Africa5 years ago
  • Very informative podcast for intensive care physician

    Informative and comprehensive.

    Apple Podcasts
    5
    Anna, London
    Netherlands6 years ago
  • Initial management of ARDS

    Excellent discussion and very helpful to bedside clinicians in early management of identifying and treating ARDS!!

    Apple Podcasts
    5
    J Amar
    United States8 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Helpful for bedside management and early ARDS understanding
Strong on critical care topics and guidelines
Informative and comprehensive for intensive care practitioners
Volume levels can vary; sound editing could improve listening experience
Feels like a rigorous ICU-focused journal club with expert insights
High-quality guests and practical, high-yield content

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Talking Points

Recent interactions between the hosts and their guests.

Sepsis - Beyond the guidelines
Q: How should antibiotics be approached in septic patients, in terms of spectrum and timing?
Early, broad-spectrum antibiotics are crucial in septic shock with high suspicion of infection, but they should be tailored to local antibiograms and tightened once culture data or rapid diagnostics guide de-escalation; delaying antibiotics increases mortality.
Sepsis - Beyond the guidelines
Q: What is the role of biomarkers in diagnosing and managing sepsis today?
Biomarkers should be interpreted in the clinical context and serially tracked to understand kinetics; single normal values early on may be misleading, and they are most informative when combined with clinical assessment and trends.
Sepsis - Beyond the guidelines
Q: From a practical standpoint, Andre, how do you define sepsis?
Sepsis is infection with new or worsening organ dysfunction, measured against the patient's baseline, acknowledging that chronic organ impairment can alter how organ failure presents and progresses.
Surviving sepsis campaign 2026 guidelines
Q: What are the key takeaways about fluid management and MAP targets?
Fluid resuscitation is usually needed early, but should be tailored with frequent reassessment; the MAP target is generally 65 mmHg with a tolerance of 60-70 mmHg and special consideration for older patients based on new evidence and ongoing trials.
Surviving sepsis campaign 2026 guidelines
Q: What is the guideline stance on the timing of antibiotic therapy?
For definite or probable sepsis, administer antimicrobial therapy immediately, ideally within one hour of recognition; for possible sepsis with lower severity, pursue rapid assessment and treat within a three-hour window if infection remains likely.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Critical Matters

What is Critical Matters about and what kind of topics does it cover?

A clinically focused series that centers on critical care, emergency support, and ICU management, often featuring expert guests who discuss epidemiology, diagnostics, and treatment strategies for life-threatening conditions. Episodes commonly explore sepsis, ARDS, ECMO, invasive infections, and guideline-based practices, interweaving practical bedside tips with implications for family communication and patient outcomes. Notable strengths include high-caliber medical guests, structured discussions of complex interventions, and a pragmatic emphasis on multidisciplinary care in ICU settings.

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Which podcasts are similar to Critical Matters?

These podcasts share a similar audience with Critical Matters:

1. Critical Care Time
2. Critical Care Scenarios
3. EMCrit FOAM Feed
4. Core IM | Internal Medicine Podcast
5. JAMA Clinical Reviews

How many episodes of Critical Matters are there?

Critical Matters launched 9 years ago and published 174 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Critical Matters?

Recent guests on Critical Matters include:

1. Lauren Ferrante
2. Grégoire Muller
3. Max Adelman
4. Dr. Hallie Prescott
5. Dr. Bram Rochwerg
6. Waqas Akhtar
7. Vasileios Panoulas
8. Mark Creager

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