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Artwork for Core Memory

Core Memory

Ashlee Vance
Artificial Intelligence
Neuroscience
Neuralink
Technology
Silicon Valley
Biotechnology
AI In Drug Discovery
Openai
Brain-Computer Interface
Connectome
China
Consciousness
Podcasting
Retinal Prosthesis
Aging
Gene Editing
Longevity Medicine
Chinese AI Companies
CRISPR
Vision Restoration

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he's written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watche... more

PublishesWeeklyEpisodes67Foundeda year ago
Number of ListenersCategories
TechnologyScience

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Artwork for Core Memory

Latest Episodes

Sam Altman and Greg Brockman came on Core Memory together for a ten-year look back at OpenAI. It’s also the first time they’ve done a media podcast together.

We juiced every second of our 90 minutes with the cofounders of OpenAI. We got into the com... more

Guinness. Sharks. American manufacturing. These are a few of the interests I share with the founders of Ulysses, a San Francisco startup building autonomous underwater drones.

The idea for Ulysses started when one of the four co-founders was on a su... more

We’re in a moment of insatiable desire for more energy and more computing. And so the ideas of how to provide said energy and computing are getting ever more adventurous.

Case in point: Panthalassa, which is the subject of this week’s episode, along... more

Three years ago, I’d caught some videos online of paralyzed people walking again. This struck me as miraculous. It also confused me. If paralyzed people were moving again, why weren’t more people talking about this incredible occurrence?

The company... more

Key Facts

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Contact Information
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Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Will O'Brien
Co-founder of Ulysses
Ulysses Vehicles
Episode: The $50,000 Underwater Drone - EP 66 Ulysses
Garth Sheldon-Coulson
Co-founder and CEO of Panthalassa
Panthalassa
Episode: The Very Wild, Very Real Plan To Build AI Data Centers In The Ocean - EP 65 Garth Sheldon-Coulson
Dave Marver
CEO of Onward Medical
Onward Medical
Episode: The Company Helping Paralyzed People Move And Thrive Again - EP 64 Dave Marver
Pedro Franceschi
CEO and co-founder of Brex
Brex
Episode: He Hacked Finance And Is Now Building An AI CEO - EP 63 Pedro Franceschi
Baiju Bhatt
Co-founder of Robinhood and founder of Aetherflux
Aetherflux
Episode: Here Come The Space Lasers - EP 62 Baiju Bhatt
Paul Conyngham
Australian dog owner who used AI to pursue a cancer therapy for his dog Rosie
Episode: The Aussie Man Who Used AI To Create A Cancer Cure For His Dog
Nabiha Saklayen
CEO and co-founder of Cellino
Cellino
Episode: Inside The Race To Reboot Human Cells - EP 60 Nabiha Saklayen
Will Wilson
CEO and co-founder of Antithesis
Antithesis
Episode: He Thinks AI Code May Break Everything - EP 59 Will Wilson
Anna Prouse
Italian journalist, Red Cross international delegate, humanitarian leader in Iraq
Red Cross / International humanitarian work
Episode: She Survived Being Shot, Bombed And Working At Google - EP 58 Anna Prouse

Hosts

Ashlee Vance
Host of Core Memory, longtime technology journalist and author
Kylie Robison
Co-host mentioned in closing credits and intro, contributing host alongside main moderator

Reviews

4.9 out of 5 stars from 84 ratings
  • My favorite podcast

    This is the one

    Apple Podcasts
    5
    tarnesen
    United States3 months ago
  • Top Tier Tech Podcast

    Ashlee is phenomenal at translating the tech expertise of innovators into digestible off-the-cuff narratives with questions that escape most interviewers. Core Memory gives you a cutting edge view into all corners of the tech industry.

    Apple Podcasts
    5
    The Tinkered Thinking Podcast
    Canada3 months ago
  • Excellent podcast

    Ashlee Vance has a broad interest in companies at the cutting edge of their fields. He gets the most interesting guests, and I often see them on other bigger podcasts a few weeks later

    Apple Podcasts
    5
    Maximus123477
    Canada8 months ago
  • If you are interested in tech, this is a must listen

    Ashlee Vance has been writing interesting, well-sourced, fact-based, entertaining stories about tech for decades. His love of some of the misfits, mad geniuses and visionaries who inhabit the tech world is tempered with equally healthy doses of skepticism and humor.

    If there’s a person making a flux capacitor in his basement, with the hope of building a time machine to go back to a simpler time when eggs were cheap and browser wars were leading the news, Ashlee has probably interviewed her and... more

    Apple Podcasts
    5
    RobMoliak
    United Statesa year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Consistently impressive curation of founders and researchers
High-quality guests and cutting-edge tech stories
Host translates complex topics into approachable narratives

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#43
United States/Technology
Apple Podcasts
#42
United Kingdom/Technology
Apple Podcasts
#47
Canada/Technology
Apple Podcasts
#48
Australia/Technology
Apple Podcasts
#62
Germany/Technology
Apple Podcasts
#93
Italy/Technology

Talking Points

Recent interactions between the hosts and their guests.

Here Come The Space Lasers - EP 62 Baiju Bhatt
Q: How does he view the role of competition, especially from much larger players like SpaceX?
He emphasizes focusing on building a viable product and path to market, arguing that strong execution and a clear niche can preserve leadership even in the face of larger incumbents.
Here Come The Space Lasers - EP 62 Baiju Bhatt
Q: Did you not, when you start, think this was the best way to use your brain and spend your time?
He explains that his love for physics and math remained the north star, but the practical need to earn a living and the lessons from the 2008 crisis pushed him into finance, where he learned to apply his training to product-market fit and, later, space energy ventures.
He Hacked Finance And Is Now Building An AI CEO - EP 63 Pedro Franceschi
Q: What was your dream as you started building in fintech and tech?
Pedro explains that from an early age he wanted to push what technology could do and believed deeply in building with a technical, vertically integrated approach, which later informed Brex's strategy.
The Aussie Man Who Used AI To Create A Cancer Cure For His Dog
Q: What is the current status of Rosie's treatment and its implications for future therapies?
Rosie has shown tumor reduction and improved energy after injections; while not a cure, the approach demonstrates potential for rapid, AI-guided personalized therapies in animals and humans, prompting broader discussions about safety and ethics.
The Aussie Man Who Used AI To Create A Cancer Cure For His Dog
Q: How did you leverage AI tools in the sequence from data gathering to therapy design?
I used ChatGPT to draft a plan, then built an ontology in Obsidian to organize drugs and mechanisms, and iteratively combined immunotherapy concepts with computational design to identify actionable targets like neoantigens and mRNA vaccine constructs.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About Core Memory

What is Core Memory about and what kind of topics does it cover?

A tech-leaning interview show that features founders, researchers, and industry executives discussing frontier science, engineering, and disruptive business models. Episodes center on ambitious hardware, biotech breakthroughs, AI, and space-scale projects, often weaving personal journeys with bold market bets, regulatory realities, and manufacturing challenges. A standout thread is the exploration of hardware-first and AI-enabled solutions at scale, from ocean robotics and autonomous data centers to brain-computer interfaces and gene-editing therapies, with a clear emphasis on how science translates into real-world impact. This mix of storytelling and expert analysis makes it a strong fit for listeners who want deep, technically grounded co... more

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1. Cheeky Pint
2. No Priors: Artificial Intelligence | Technology | Startups
3. Sourcery
4. The MAD Podcast with Matt Turck
5. TBPN

How many episodes of Core Memory are there?

Core Memory launched a year ago and published 67 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Core Memory?

Recent guests on Core Memory include:

1. Will O'Brien
2. Garth Sheldon-Coulson
3. Dave Marver
4. Pedro Franceschi
5. Baiju Bhatt
6. Paul Conyngham
7. Nabiha Saklayen
8. Will Wilson

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