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Concentrating on Chromatography

David Oliva
Chromatography
Mass Spectrometry
PFAS
Analytical Chemistry
Gas Chromatography
HPLC
Sample Preparation
PFAS Detection
Lc-Ms
Filtration
Separation Science
Syringe Filters
Labexact
Glp-1 Peptides
Gc-Ms
Comprehensive Two-Dimensional Gas Chromatography
High-Resolution Mass Spectrometry
Complex Chemical Composition Analysis Lab
Liquid Chromatography-Mass Spectrometry
Sustainability

Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers pra... more

PublishesTwice weeklyEpisodes61Foundeda year ago
Number of ListenersCategories
ScienceChemistry

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Artwork for Concentrating on Chromatography

Latest Episodes

In this episode of @ChromatographyTalk David speaks with Colette Quinn, Senior Director within the Biologics Business at Waters Corporation, about the rapidly evolving world of pharmaceutical and biopharma QA/QC.As biologics become more complex, QA... more

What makes capillary LC so powerful—and why are more scientists paying attention to it?In this episode of @ChromatographyTalk , David sits down with Samuel Foster of Axcend to discuss how capillary liquid chromatography is changing the conversation ... more

How are PFAS regulations changing, and what role will ion chromatography play in the future of environmental testing?In this episode of @ChromatographyTalk , David interviews Jay Gandhi, PhD, Vertical Markets Manager at Metrohm USA, for an in-depth ... more

What do students really learn before they ever touch an analytical instrument? And is chemistry education keeping up with the pace of modern chromatography, mass spectrometry, and sample preparation?In this episode of Concentrating on Chromatography,... more

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Recent Guests

Samuel Foster
Industry expert from Axcend
Axcend
Episode: Episode 60: Why Capillary LC Is the Future of LC-MS Sensitivity #chromatography #massspectrometry
Jay Gandhi
Vertical Markets Manager at Metrohm USA
Metrohm USA
Episode: Episode 59: The Future of Ion Chromatography | PFAS Testing, EPA 1621 & AOF Explained #analyticalchemistry
Natasha Le
Chemistry instructor working with general chemistry, organic chemistry, and laboratory education
La Sierra University
Episode: Episode 58: How Separation Science Is Taught vs. How It’s Actually Used #nmrspectroscopy #massspectrometry
Rajas Poorna
PI and collaborator on Evapinator project
Baumler Lab / Frugal Science Academy
Episode: Episode 57: Frugal Science Meets Sample Prep: A Field-Ready Lyophilizer for Biofluids
Charles Anderson
Collaborator on Evapinator project
Georgia Tech / Bauma Lab
Episode: Episode 57: Frugal Science Meets Sample Prep: A Field-Ready Lyophilizer for Biofluids
Christopher Reid
Researcher focusing on chemical biology and LC-MS applications for antimicrobial resistance
Brown University (collaboration mentioned)
Episode: Episode 56: Fighting Antibiotic Resistance with LC-MS: Targeting Bacterial Cell Walls #chromatography #massspec
Leigh Terry
Professor, University of Alabama; Water Quality Lab lead
University of Alabama
Episode: Episode 55: PFAS in Water: Why We’re Missing 96% of the Problem | Dr. Leigh Terry #analyticalchemistry
Amanda Guiraldelli Mahr
Analytical chemist with extensive experience in LC-MS, method development, and AQbD across small molecules, biopharmaceuticals, and oligonucleotides
Contract research and standards; USP background
Episode: Episode 54: AQbD Explained: How Design of Experiments is Transforming Chromatography (LC-MS, Pharma & Biopharma)
Kelly Broster McMahon
Senior Manager in Market Development and Collaborations at Thermo Fisher Scientific
Thermo Fisher Scientific
Episode: Episode 53: How GLP-1 Drugs Are Analyzed: Chromatography & Mass Spectrometry Explained #analyticalchemistry

Host

David Oliva
Host of the show, leading discussions on chromatography and analytical chemistry with notable experts in the field.

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Episode 60: Why Capillary LC Is the Future of LC-MS Sensitivity #chromatography #massspectrometry
Q: What makes capillary LC fundamentally different from traditional HPLC, and where does it deliver the biggest advantages?
Capillary LC operates at much smaller inner diameters, requiring much lower flow rates, which reduces solvent usage and enhances ionization efficiency in ESI-MS, translating into potentially four to tenfold gains in sensitivity when set up correctly.
Episode 60: Why Capillary LC Is the Future of LC-MS Sensitivity #chromatography #massspectrometry
Q: Can you briefly walk us through your path from your Ph.D. at Rowan to your current role at Axcend, and what got you focused on capillary LC to begin with?
My advisor Jim Grinius played a pivotal role, encouraging me into chromatography early on and steering me toward capillary techniques, which then shaped my career and focus, leading to my work with Axcend.
Episode 59: The Future of Ion Chromatography | PFAS Testing, EPA 1621 & AOF Explained #analyticalchemistry
Q: How do regulatory frameworks around PFAS evolve beyond drinking water?
The guest outlines a global alignment prioritizing reduction of PFAS production and environmental release, with wastewater and then drinking water as focus areas, and explains the potential pathway for AOF to become a regulatory tool as screening before formal regulation.
Episode 59: The Future of Ion Chromatography | PFAS Testing, EPA 1621 & AOF Explained #analyticalchemistry
Q: What initially drew you to ion chromatography, and how has the field evolved over your career?
The guest explains a NASA-linked start with IC for water analysis and notes how Metrohm helped broaden IC into food, environmental, and industrial applications, including semiconductors and batteries.
Episode 58: How Separation Science Is Taught vs. How It’s Actually Used #nmrspectroscopy #massspectrometry
Q: Can you tell us about your current role as an instructor?
Natasha describes teaching general chemistry, an organic chemistry lab, and introductory chemistry, with a focus on how foundational concepts in separation science are introduced early and later reinforced through more advanced courses and lab work.

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Conversations focus on the evolving landscape of chromatography, mass spectrometry, and analytical chemistry, featuring experts discussing innovative technologies and research. Key topics include advancements in sample preparation, the environmental impact of chemical detection, and practical applications of chromatography in various fields including pharmacology, environmental science, and food safety. Each episode provides insights from leading figures in the industry, making complex scientific concepts accessible and relevant to both professionals and students alike, which likely appeals to a community eager to stay abreast of technical developments and best practices in analytical methods.

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1. The Proteomics Show

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Concentrating on Chromatography launched a year ago and published 61 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Concentrating on Chromatography?

Recent guests on Concentrating on Chromatography include:

1. Samuel Foster
2. Jay Gandhi
3. Natasha Le
4. Rajas Poorna
5. Charles Anderson
6. Christopher Reid
7. Leigh Terry
8. Amanda Guiraldelli Mahr

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