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Concentrating on Chromatography

David Oliva
Chromatography
Mass Spectrometry
PFAS
Analytical Chemistry
Gas Chromatography
Sample Preparation
HPLC
My Green Lab
Metabolomics
Lc-Ms
PFAS Detection
Filtration
Separation Science
Syringe Filters
Labexact
Glp-1 Peptides
Gc-Ms
Comprehensive Two-Dimensional Gas Chromatography
High-Resolution Mass Spectrometry
Complex Chemical Composition Analysis Lab

Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers pra... more

PublishesWeeklyEpisodes82Founded2 years ago
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ChemistryScience

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Latest Episodes

He built a gas chromatograph and mass spectrometer small enough to fit in a carry-on suitcase, then hauled it up a 43-meter tower in 100-degree Alabama heat to catch invisible forest chemicals in real time.

Austin "Augie" Dobrecevich, a PhD research... more

Arielle Cocozza, National Technical PFAS Lead at ALS USA Environmental, joins David Oliva and Candi Gokey to break down the current state of PFAS analysis — from her unconventional path out of a physics degree into environmental chemistry, to standar... more

Mauricio Caraballo, PhD, director of the MSCollaboratory at UC San Diego, joins Candi Gokey and host David Oliva to unpack how untargeted LC-MS/MS metabolomics reveals hidden chemistry in coral reefs, fish, and ocean water. They dig into molecular ne... more

Mechanical engineer Mason Chilmonczyk, PhD (Andson Biotech) joins host David Oliva to explain why sample prep — not the mass spec itself — is the biggest bottleneck in LC-MS and native MS workflows. Mason breaks down the DynaChip, a microfluidic devi... more

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Recent Guests

Arielle Cocozza
National Technical PFAS Lead with ALS USA Environmental
ALS USA Environmental
Episode: Episode 81: PFAS, 6PPD-Quinone & the Science of Emerging Contaminants w/ Arielle Cocozza (ALS USA)
Mauricio Caraballo
Leader of the MSCollaboratory metabolomics initiative
MSC collaboration Lab / Colombia
Episode: Episode 80: Untargeted Metabolomics & Ocean Chemistry with Mauricio Caraballo
Mason Chilmonczyk
Founder of Anson Biotech, mechanical engineer focused on inline mass spectrometry workflows
Anson Biotech
Episode: Episode 79: Mechanical engineer Mason Chilmonczyk on fixing mass spec's bubbles, clogs, and leaks
Matthew Lewis
Dr. involved in Bruker collaboration and the development of hybrid metabolomics platforms
Bruker
Episode: Episode 77: Hybrid Metabolomics Explained: Bridging Targeted & Untargeted MS with Bruker's Matthew Lewis
Viktoria Müller
Postdoctoral researcher
University of Graz
Episode: Episode 76: PFAS Are Everywhere — And 99% Go Undetected | Dr. Viktoria Müller
PH Stefanuto
Researcher and co-organizer of the Multidimensional Chromatography Workshop
Episode: Episode 75: Breathomics, Asthma & GC×GC: PH Stefanuto on Fighting the “Proof‑of‑Concept” Trap
Jacob Russell
PhD student researching glycoproteomics and analytical chemistry
University of Washington (Riley Lab)
Episode: Episode 74: Decoding the Glycocode: AI-Powered Glycoproteomics & Cancer Research | Jacob Russell (Riley Lab, UW)
Madalyn Radlauer
Associate Professor of Chemistry at San Jose State University
San Jose State University
Episode: Episode 73: How Chromatography Helps Build Better Catalysts | Dr. Madalyn Radlauer (San José State University)
Michelle Taylor
Editor-in-Chief LabCompare
LabCompare
Episode: Episode 72: PFAS in Water, Food & Packaging: Michelle Taylor on the "Forever Chemicals" Documentary Series

Host

David Oliva
Host of Concentrating on Chromatography

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Episode 80: Untargeted Metabolomics & Ocean Chemistry with Mauricio Caraballo
Q: What is the value of the Pan-REDU/Redu metadata framework in metabolomics workflows?
Redu and Pan-Redu provide standardized metadata, enabling living data and cross-dataset searching across repositories, which improves data reuse, reproducibility, and the ability to trace sample provenance and experimental conditions over time.
Episode 80: Untargeted Metabolomics & Ocean Chemistry with Mauricio Caraballo
Q: How can researchers get started with the MSCollaboratory and collaborate on a project?
Researchers can initiate contact, participate in office hours, submit a project description, and work with the team to design sample prep, data acquisition, and data analysis workflows, with training opportunities and the option for hands-on involvement.
Episode 78: SPME, PFAS & Green Chemistry with Dr. Emanuela Gionfriddo
Q: What is the current outlook for ambient ionization and portable platforms for PFAS or pesticide screening in the field?
Pesticide screening via portable techniques shows promise for re-concentration and rapid screening, but for PFAS, on-site analysis remains challenging due to the need for high sensitivity and complex matrices. We are cautiously optimistic but not yet at a point where field devices can replace lab-based quantification for PFAS at very low levels.
Episode 78: SPME, PFAS & Green Chemistry with Dr. Emanuela Gionfriddo
Q: What makes mascara PFAS studies particularly challenging, and why did you use two extraction approaches?
Cosmetics are highly complex and formulation-dependent, with significant brand-to-brand variability. Using both SPME and automated micro-SPE allowed us to compare manual vs. automated workflows, optimize cleanup and matrix matching, and show that calibration must be done in exactly the same mascara matrix to account for formulation differences.
Episode 78: SPME, PFAS & Green Chemistry with Dr. Emanuela Gionfriddo
Q: Could you explain why your group focuses on green analytical methodologies and how that translates into practical method optimization?
The approach is inherently miniaturized and solvent-minimized, which reduces waste and energy usage while maintaining analytical performance. It also aligns with the 12 principles of green analytical chemistry, guiding method selection to be environmentally friendlier and more sustainable without sacrificing accuracy.

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Frequently Asked Questions About Concentrating on Chromatography

What is Concentrating on Chromatography about and what kind of topics does it cover?

A rigorous and industry-facing show that centers on chromatography, mass spectrometry, and sample preparation, featuring candid conversations with leading researchers, developers, and practitioners. Episodes frequently tackle cutting-edge methods, practical workflows, and real-world challenges—ranging from PFAS detection and environmental analytics to AI-assisted chromatography and sustainable lab practices. The focus is on transferable insights: method development strategies, instrument workflows, data interpretation, and the evolving role of analytics in research, industry, and policy. A notable strength is the mix of academia and industry voices, offering both foundational theory and hands-on implementations, which makes it valuable for ... more

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Concentrating on Chromatography launched 2 years ago and published 82 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Concentrating on Chromatography?

Recent guests on Concentrating on Chromatography include:

1. Arielle Cocozza
2. Mauricio Caraballo
3. Mason Chilmonczyk
4. Matthew Lewis
5. Viktoria Müller
6. PH Stefanuto
7. Jacob Russell
8. Madalyn Radlauer

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