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Clinical Trialblazers

Parexel
Clinical Trials
Biotechnology
Oncology
Drug Development
Biotech Innovation
Pharmaceutical Industry
Innovation In Medicine
Biotech
Scientific Innovation
Medical Treatments
Pediatric Oncology
Splice Bio
Venture Capital
Gene Therapy
Leadership
Regulatory Landscape
Funding
Biotech Industry
Mentorship
Parkinson's Disease

Clinical Trialblazers invites you into the world of biotech leaders as they share the untold stories behind their journeys to bring breakthrough innovations to life. This 10 episode monthly series asks biotech visionaries to explore pivotal moments in their careers and the milestones that shaped their lives. Through unscripted conversations, host Alberto Grignolo dives into the decisions, risks, a... more

PublishesMonthlyEpisodes13Foundeda year ago
Number of ListenersCategories
Health & FitnessLife SciencesScienceMedicine

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Artwork for Clinical Trialblazers

Latest Episodes

Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawin... more

Clinical Trialblazers will be back soon! Season 2 will bring together a dynamic mix of biotech innovators, executives, and industry leaders to reveal the strategy and teamwork fueling the next wave of clinical breakthroughs. Across 10 new episodes, h... more

In this season finale of Clinical Trialblazers, host Alberto Grignolo reflects on key insights and themes from conversations with biotech leaders over the past year. From researchers to entrepreneurs to investors, Alberto spoke with a wide range of l... more

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In this episode of Clinical Trialblazers, Alberto sits down with Dr. Geeta Vemuri, Founder and Managing Partner of Agent Capital. They discuss Dr. Vemuri’s journey into venture capital, offering valuable insights on what makes successful biotech comp... more

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Recent Guests

Paul Garofolo
CEO and Co-founder of Locus Biosciences
Locus Biosciences
Episode: Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO
Dr. Geeta Vemuri
A force in biotech investing and a champion for translating science into real world impact.
Agent Capital
Episode: Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
Miquel Vila-Perello
Co-founder and CEO of Splice Bio, a gene therapy company
Splice Bio
Episode: Breaking Barriers in Gene Therapy: Miquel Vila-Perello's Vision for Curing Untreatable Diseases
Lyla Bibi
Partner at Goldman Sachs and head of their Healthcare Equity Capital Markets business
Goldman Sachs
Episode: Investing in Innovation: Lyla Bibi’s Perspective on Biotech Markets
Dr. Antti Vuolanto
Chief Executive Officer of Herantis Pharma, with extensive experience in research and development.
Herantis Pharma
Episode: The Finnish Formula: Finding Balance and Building Innovation with Dr. Antti Vuolanto
Dr. Ross Breckenridge
CEO of Arjuna Therapeutics, physician, cardiac biologist, and biotech executive
Arjuna Therapeutics
Episode: Leading with Science and Heart: Dr. Ross Breckenridge on Building a Resilient Biotech
Dr. Sam Blackman
Co-founder and former chief medical officer of Day One Biopharmaceuticals, board member of the Pediatric Brain Tumor Foundation, Bonum Therapeutics, and Cure Research for Children's Cancer.
Episode: Bedside to Biotech: Dr. Sam Blackman on Building Trust, Storytelling in Science, and Pediatric Cancer Innovation
Kerrie Brady
Biotech founder, executive, and board member with a 40-year career in pharmaceutical and biotech industries
Episode: From Mentee to CEO, Board Member and Mentor: Insights from Kerrie Brady
Robert Blum
President and CEO of Cytokinetics
Cytokinetics
Episode: Leading Through Setbacks with Cytokinetics’ Robert Blum

Host

Alberto Grignolo
Host of Clinical Trialblazers

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Talking Points

Recent interactions between the hosts and their guests.

Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO
Q: What lessons from fundraising would you share with future biotech founders?
Be prepared for substantial no's and long cycles; diversify financing approaches (equity, non-dilutive deals), and ensure you understand the regulatory data that regulators actually require, so you avoid chasing peripheral data that delays milestones.
Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO
Q: How did you decide to pick the acute urinary tract infection indication as a first clinical target?
The choice was driven by a mix of data cadence and therapeutic relevance, with E. coli being a well-understood target that could demonstrate platform validity, while enabling catheter-based delivery in the bladder to provide proof of concept.
Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO
Q: What experiences shaped your thinking about capital efficiency and resource prioritization as a CEO?
Garofolo highlights centralized planning with decentralized execution as a driver of speed and adoption, and stresses that time kills programs; shorter, deliberate steps with quick data wins help manage risk and keep projects in the clinic.
Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
Q: What advice would you give to emerging investment and biotech leaders?
For younger people, promote yourself without arrogance; for older leaders, focus on capital efficiency to maximize returns.
Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
Q: How did your scientific background help you evaluate opportunities for investment?
My scientific background allows me to understand the nuances of biology and chemistry important for investment decisions in biopharma.

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Frequently Asked Questions About Clinical Trialblazers

What is Clinical Trialblazers about and what kind of topics does it cover?

This series spotlights biotech leaders and the human stories behind breakthrough science, focusing on the decisions, risks, and milestones that shaped their paths from academia to industry leadership. Episodes center on fundraising strategies, partnership dynamics, regulatory milestones, and real-world lessons learned while building and scaling biotech programs. A distinctive thread is the emphasis on resilience, storytelling in drug development, leadership growth, and the evolving funding landscape for innovative therapeutics. Listeners can expect candid, unscripted conversations with founders, CEOs, investors, and seasoned operators who translate science into market impact, along with practical takeaways for navigating clinical trials, pa... more

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How many listeners does Clinical Trialblazers get?

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Which podcasts are similar to Clinical Trialblazers?

These podcasts share a similar audience with Clinical Trialblazers:

1. BioCentury This Week
2. Biotech Hangout
3. The Readout Loud
4. The Top Line
5. Nature Podcast

How many episodes of Clinical Trialblazers are there?

Clinical Trialblazers launched a year ago and published 13 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Clinical Trialblazers?

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What guests have appeared on Clinical Trialblazers?

Recent guests on Clinical Trialblazers include:

1. Paul Garofolo
2. Dr. Geeta Vemuri
3. Miquel Vila-Perello
4. Lyla Bibi
5. Dr. Antti Vuolanto
6. Dr. Ross Breckenridge
7. Dr. Sam Blackman
8. Kerrie Brady

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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