Clinical Chemistry Podcast

Association for Diagnostics and Laboratory Medicine

Alzheimer's Disease

Machine Learning

Laboratory Medicine

Clinical Chemistry

Biomarkers

Clinical Laboratories

Myocardial Infarction

Chronic Kidney Disease

Cardiovascular Disease

Pregnancy

Cardiovascular Events

FDA

Proteomics

Tuberculosis

Covid-19

Clinical Trials

Vitamin D

Cell-Free DNA

Mass Spectrometry

Sepsis

This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory.

59 ratings

Publishes	Weekly	Episodes	1100	Founded	14 years ago
Number of Listeners		Categories	ScienceMedicineChemistryHealth & Fitness

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Latest Episodes

Fecal Microbiota Therapy: Clinical Laboratory Testing and Metabolomic Approaches for Donor Screening, Product Assessment, and Patient Monitoring

Grace Drew, Colleen S Kraft, Nirja Mehta. Fecal Microbiota Therapy: Clinical Laboratory Testing and Metabolomic Approaches for Donor Screening, Product Assessment, and Patient Monitoring. Clinical Chemistry, Volume 72, Issue 5, May 2026, Pages 554–56... more

Yesterday • 13 min

Audio Summary June 2026

22 May 2026 • 5 min

Diagnostic Value of Serum p-tau217 in Alzheimer Disease: Equal to Plasma in Levels and Clinical Utility?

Andrea L Benedet, Burak Arslan, Kubra Tan, Hanna Huber, Ilaria Pola, Guglielmo Di Molfetta, Hlin Kvartsberg, Anna Orduña Dolado, Shorena Janelidze, Kaj Blennow, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Nicholas J Ashton. Diagnostic Value of... more

18 May 2026 • 14 min

Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis

Denise M O'Sullivan, Gerwyn M Jones, Manca Zolnir-Dovc, Richard Phillips, Rejoice Arthur, Bariki Mtafya, Daniel Adon Mapamba, Daniela Maria Cirillo, Ewa Augustynowicz-Kopeć, Mei Mei Ho, Belinda Dagg, Sven O Friedrich, Francesca Colavita, Antonella Vu... more

13 May 2026 • 9 min

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Recent Guests

Burak Arslan

Lead author of the referenced study on serum vs plasma p-tau-217

Clinical Neurochemistry Laboratory, Solgrenska University Hospital, Gothenburg, Sweden

Episode: Diagnostic Value of Serum p-tau217 in Alzheimer Disease: Equal to Plasma in Levels and Clinical Utility?

Dr. Denise O'Sullivan

Principal Scientist in Analytical Microbiology

National Measurement Laboratory, Guildford, United Kingdom

Episode: Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis

Thomas Durant

Associate professor of laboratory medicine and biomedical informatics and data science at Yale School of Medicine

Yale School of Medicine

Episode: Quantum Machine Learning and Data Re-Uploading: Evaluation on Benchmark and Laboratory Medicine Data Sets

Wayne Schulz

Associate professor of laboratory medicine and computational healthcare researcher at Yale School of Medicine

Yale School of Medicine

Episode: Quantum Machine Learning and Data Re-Uploading: Evaluation on Benchmark and Laboratory Medicine Data Sets

Adam McShane

Staff member in the Department of Pathology and Laboratory Medicine at Cleveland Clinic, Medical Director of the Special Chemistry Laboratory

Cleveland Clinic

Episode: Scientific Fraud at Scale: Challenges for Trust in Published Data

Preejith P. Vachali

Clinical Chemistry Fellow at the Cleveland Clinic

Cleveland Clinic

Episode: Scientific Fraud at Scale: Challenges for Trust in Published Data

Yusheng Zhu

Professor and Vice Chair for Academic Affairs in the Department of Pathology and Laboratory Medicine, Adjunct Professor of Molecular and Precision Medicine at Penn State College of Medicine, Hershey, Pennsylvania

Penn State College of Medicine

Episode: Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing

Imir Metushi

Assistant Professor at UCLA; Director of the Pathology Research Portal

University of California, Los Angeles

Episode: Endogenous Lithium Levels and Alzheimer Disease

Ray Suhandynata

Associate Professor at UC San Diego; Co-Director of the Clinical Toxicology Laboratory

University of California, San Diego

Episode: Endogenous Lithium Levels and Alzheimer Disease

Host

Bob Barrett

Host of Clinical Chemistry Podcast, guiding interviews and introducing guests

Reviews

4.3 out of 5 stars from 59 ratings

Clinical chem
Amazing podcast on biochemistry...great for physicians and graduate students!
Apple Podcasts
5
The-Thingi
United States11 years ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests are well-qualified and bring practical lab insights for real-world impact.

Content is consistently rigorous and informative for lab professionals.

Listeners appreciate accessible deep dives into complex diagnostics and research.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#14	United States/Science/Chemistry
Apple Podcasts	#11	United Kingdom/Science/Chemistry
Apple Podcasts	#27	Canada/Science/Chemistry
Apple Podcasts	#9	Germany/Science/Chemistry
Apple Podcasts	#12	Australia/Science/Chemistry
Apple Podcasts	#42	France/Science/Chemistry

Talking Points

Recent interactions between the hosts and their guests.

Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis

Q: Doctor, why would one use digital PCR for this approach?

Digital PCR allows absolute counting of target molecules by partitioning a sample into thousands of tiny reactions, enabling precise quantification of both the pathogen and resistance markers and offering the potential for SI traceability in diagnostic measurements.

Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis

Q: And Dr. O'Sullivan, let's get basic first. Why is accurate testing important for molecular diagnostics?

Accurate testing ensures that results closely reflect the true biological state, enabling early disease detection, effective monitoring, and appropriate treatment decisions, which is especially critical in infectious diseases like tuberculosis to prevent treatment failure and the development of further resistance.

Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing

Q: Why is HIV self-testing for PrEP important, and what are its limitations?

Self-testing offers privacy, convenience, and faster results, potentially increasing PrEP uptake; however, it risks missing recent infections during the window period and may require more advanced molecular methods for early detection.

Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing

Q: What roles do clinical laboratorians play in the HIV PrEP program?

Laboratories perform initial HIV screening and confirmation using antigen-antibody immunoassays, with reflex testing for confirmation; they also conduct baseline and ongoing monitoring for other markers and STIs.

Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing

Q: Tell us some of that background.

Dr. Zhu explains the basics of PrEP, distinguishing it from PEP, and notes that PrEP requires ongoing daily or regular use of antiretroviral medications to prevent HIV infection in at-risk individuals.

Audience Metrics

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Frequently Asked Questions About Clinical Chemistry Podcast

What is Clinical Chemistry Podcast about and what kind of topics does it cover?

A scientifically minded show that surveys advances and challenges in clinical chemistry, laboratory medicine, and diagnostics. Across episodes, topics range from QA and standardization in molecular testing for infectious diseases, to novel tech like digital PCR and quantum machine learning applied to healthcare data, to systemic issues such as fraud in scientific publishing and gaps in maternal testing. The program frequently features clinicians and researchers from top institutions discussing practical implications for labs, patient care, and policy. A standout pattern is bridging lab science with real-world applications, often highlighting emerging diagnostics, regulatory landscapes, and the future of precision medicine.

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How many listeners does Clinical Chemistry Podcast get?

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Which podcasts are similar to Clinical Chemistry Podcast?

These podcasts share a similar audience with Clinical Chemistry Podcast:

1. Science Magazine Podcast
2. How to Be a Better Human
3. Nature Podcast
4. 潘吉Jenny告诉你|学英语聊美国|开言英语 · Podcast
5. The Exam Room by the Physicians Committee

How many episodes of Clinical Chemistry Podcast are there?

Clinical Chemistry Podcast launched 14 years ago and published 1100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Clinical Chemistry Podcast?

Recent guests on Clinical Chemistry Podcast include:

1. Burak Arslan
2. Dr. Denise O'Sullivan
3. Thomas Durant
4. Wayne Schulz
5. Adam McShane
6. Preejith P. Vachali
7. Yusheng Zhu
8. Imir Metushi

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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