Clinical Chemistry Podcast

Association for Diagnostics and Laboratory Medicine

Alzheimer's Disease

Machine Learning

Laboratory Medicine

Clinical Chemistry

Biomarkers

Myocardial Infarction

Clinical Laboratories

Chronic Kidney Disease

Cardiovascular Disease

Pregnancy

Cardiovascular Events

FDA

Proteomics

Tuberculosis

Covid-19

Clinical Trials

Digital PCR

Vitamin D

Cell-Free DNA

Mass Spectrometry

This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory.

60 ratings

Publishes	Weekly	Episodes	1110	Founded	15 years ago
Number of Listeners		Categories	ChemistryHealth & FitnessMedicineScience

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Guests Host Reviews Charts Talking Points

Latest Episodes

Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial

Luuk F P Giesen, Jeroen A Roest, Frederique M A Koopman, Martine M L Deckers, Helena Chon, Christian M Hackeng, Jurgen A Riedl, Michiel de Bruin, Brooke M Katzman, Warry van Gelder, Janne Cadamuro, Mads Nybo, Michael A Fouraux, Thijs C van Holten, Ro... more

5 Aug 2026 • 9 min • Most popular

Exploring Sex-Specific High-Sensitivity Cardiac Troponin Thresholds for Rule-Out of Non-ST-Elevation Myocardial Infarction

Ingar Ziad Restan, Yong Yong Tew, Ole-Thomas Steiro, Ziwen Li, Hilde L Tjora, Jørund Langørgen, Torbjørn Omland, Paul Collinson, Rune Bjørneklett, Kjell Vikenes, Trude Steinsvik, Øyvind Skadberg, Øistein R Mjelva, Alf Inge Larsen, Vernon V S Bonarjee... more

5 Aug 2026 • 10 min

Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

Juexiao Sherry Wang, C J Battey, Kyle Trettin, Ravi Patel, Anu Srinivasan, Janani Saikumar, Divya Kushnoor, Ben F Habermeyer, Sangita Ganesh, Nafei Xu, Nathaniel Friedrich, Summer Pierson, Helen Wan, Heather LaBreche, Genevieve M Gould, Dale Muzzey. ... more

27 Jul 2026 • 13 min

Audio Summary August 2026

24 Jul 2026 • 5 min

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Recent Guests

Luuk Giesen

Chief Medical Officer of VITESTRO

VITESTRO

Episode: Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial

Ingar Ziad Restan

Cardiologist, lead author of the study discussed in the episode

Stavanger University Hospital, Stavanger, Norway

Episode: Exploring Sex-Specific High-Sensitivity Cardiac Troponin Thresholds for Rule-Out of Non-ST-Elevation Myocardial Infarction

Dale Muzzey

Chief Scientific Officer at Myriad Genetics

Myriad Genetics

Episode: Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

Dr. Jeff Meeusen

Lead author; Mayo Clinic; lipid and lipoprotein testing

Mayo Clinic

Episode: From Pooled Cohorts to PREVENT: A Perspective for Clinical Laboratorians

Anna Hoge

Resident physician in internal medicine; microbiome and genomics research

University of Washington

Episode: Disseminated Coccidioidomycosis in Immunocompetent Hosts: Opportunities for Increased Recognition and Timely Diagnosis

Erin Graf

Associate professor and co-director of microbiology

Mayo Clinic in Phoenix, Arizona

Episode: Disseminated Coccidioidomycosis in Immunocompetent Hosts: Opportunities for Increased Recognition and Timely Diagnosis

Ann Moyer

Professor of Laboratory Medicine and Pathology at Mayo Clinic; molecular genetic pathologist specializing in pharmacogenomics, renal genetics, and inborn errors of immunity

Mayo Clinic

Episode: DPYD Sequencing Identifies More Clinically Relevant Variants as Compared to Targeted Genotyping

Peter Freeman

Senior author of the study; lecturer in healthcare sciences at the University of Manchester; developer of Variant Validator

University of Manchester; Variant Validator

Episode: Universal Presence of Gene/Variant Nomenclature Errors in Journal Manuscript Submissions

Patrick Bossuyt

Professor of clinical epidemiology; lead author of the discussed article

University of Amsterdam / Amsterdam UMC Biomarker and Test Evaluation Research Program

Episode: Frameworks of Health Outcomes for Performance Specifications in Laboratory Medicine

Host

Bob Barrett

Host of Clinical Chemistry Podcast

Reviews

4.3 out of 5 stars from 60 ratings

Clinical chem
Amazing podcast on biochemistry...great for physicians and graduate students!
Apple Podcasts
5
The-Thingi
United States11 years ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High-quality guests and rigorous scientific depth.

Great for staying current on lab medicine advances.

Clear explanations of complex topics without overselling science.

Thoughtful, evidence-driven discussions that are practical for labs to act on.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#12	United States/Science/Chemistry
Apple Podcasts	#22	Canada/Science/Chemistry
Apple Podcasts	#33	United Kingdom/Science/Chemistry
Apple Podcasts	#36	France/Science/Chemistry
Apple Podcasts	#36	Germany/Science/Chemistry
Apple Podcasts	#39	Australia/Science/Chemistry

Talking Points

Recent interactions between the hosts and their guests.

Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial

Q: Can you explain the benefits of multimodal imaging for the ARPD?

Multimodal imaging combines near-infrared for initial vein modeling with ultrasound to assess depth and diameter, and Doppler to confirm blood flow direction and ensure the vessel is a vein, collectively improving safety and success for venipuncture.

Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

Q: What benefits are associated with a single simultaneous screen, and how early can clinicians rely on this test?

Clinicians can obtain comprehensive results earlier in pregnancy (as early as eight weeks, with validated performance at ten weeks and beyond) without sacrificing accuracy in any individual component, accelerating diagnostic follow-up decisions.

Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility

Q: What makes this different from traditional screenings, and what problem does the first gene screen solve by bringing these into one simultaneous cell-free DNA test?

The test brings together aneuploidy screening, recessive single-gene information, and fetal–maternal blood compatibility into a single, rapid result, removing the need for separate tests and multiple blood draws, and enabling clinicians to see all three types of information within one patient visit.

Exploring Sex-Specific High-Sensitivity Cardiac Troponin Thresholds for Rule-Out of Non-ST-Elevation Myocardial Infarction

Q: You evaluated this question in two independent cohorts and across three high-sensitivity troponin assays. Could you walk us through the study design?

We used about 2,000 patients from the derivation cohort (Westcorps) in Norway and externally validated in Edinburgh, with three assays (Roche Troponin T, Abbott Troponin I, and Siemens Troponin I) to test sex-specific vs uniform thresholds for MI rule-out.

From Pooled Cohorts to PREVENT: A Perspective for Clinical Laboratorians

Q: What are the clinical implications of PREVENT for statin eligibility?

PREVENT lowers the risk threshold for initiating discussion about lipid-lowering therapy, meaning more patients may become eligible for statins if they follow the revised guidance while still maintaining clinician-patient shared decision making.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Clinical Chemistry Podcast

What is Clinical Chemistry Podcast about and what kind of topics does it cover?

This show centers on clinical laboratory medicine, biomarkers, and diagnostic technologies, featuring in-depth conversations with researchers, clinicians, and industry experts. Episodes frequently explore device performance, analytical methods, and real-world implementation—from autonomous phlebotomy and troponin thresholds to prenatal screening, pharmacogenomics, and MDR-TB testing. A standout pattern is the strong emphasis on how laboratory science translates to patient care, workflow efficiency, and decision-making in diverse settings. Noteworthy are cross-disciplinary guests, rigorous methodological discussions, and practical takeaways for labs considering new tests, instruments, or practices.

Listeners likely include blood-bank and di... more

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Which podcasts are similar to Clinical Chemistry Podcast?

These podcasts share a similar audience with Clinical Chemistry Podcast:

1. JAMA Clinical Reviews
2. JAMA Editors' Summary
3. Hidden Brain
4. Think Fast Talk Smart: Communication Techniques
5. TED Radio Hour

How many episodes of Clinical Chemistry Podcast are there?

Clinical Chemistry Podcast launched 15 years ago and published 1110 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Clinical Chemistry Podcast?

Recent guests on Clinical Chemistry Podcast include:

1. Luuk Giesen
2. Ingar Ziad Restan
3. Dale Muzzey
4. Dr. Jeff Meeusen
5. Anna Hoge
6. Erin Graf
7. Ann Moyer
8. Peter Freeman

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