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Sepsis
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This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory.

PublishesWeeklyEpisodes1074Founded14 years ago
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Health & FitnessScienceChemistryMedicine

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Recent Guests

Dr. Garrett Martens
A board-certified clinical pathologist specializing in molecular assays and liquid biopsy testing, oncology, and prenatal screening.
AZ Delta General Hospital, Belgium
Episode: Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Dr. Nicholas Larky
Clinical chemist and assistant professor of pathology at the University of Virginia
University of Virginia
Episode: Risk vs Prevalence: Weighing Routine DPYD Variant Testing Prior to Fluoropyrimidine-Based Chemotherapy
Dr. Walter Craft
Internist and clinical pharmacologist at Sidney Kimmel Medical College, focusing on early phase drug development and clinical pharmacology.
Sidney Kimmel Medical College
Episode: Optimizing Estimation: Perspective on Drug Dosing Using New CKD-EPI Equations
Dr. Osna Arsund
Director of the Norwegian Quality Improvement of Laboratory Examinations and a consultant at the Norwegian Porphyria Center
Haukland University Hospital, Bergen, Norway
Episode: Utilizing the Stability of Individual Homeostatic Setpoints over Time - A Step Forward on the Path to Personalized Laboratory Medicine
Dr. Joshua Lieberman
Associate professor of laboratory medicine and pathology at the University of Washington
University of Washington
Episode: Advances in Syphilis Diagnostics to Address the 21st-Century Epidemic
Dr. Yixin Chang
Attending physician in the emergency department at China Medical University Hospital and involved in AI integration in clinical practice
China Medical University Hospital
Episode: Machine Learning for Detecting Iron Deficiency through Comprehensive Blood Analysis
Dr. Hans Lilje
Clinical chemist with Memorial Sloan Kettering Cancer Center and an emeritus professor in the Department of Translational Medicine at Lund University, Malmo, Sweden
Memorial Sloan Kettering Cancer Center
Episode: Toward Improved Prostate Cancer Screening: Insights from the Göteborg-2 Trial
Dr. Jesse Sigmiller
Associate professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota, board-certified clinical chemist, and laboratory director for M Health Fairview.
University of Minnesota
Episode: Proteomic Aging Clock Predicts Mortality and Risk of Common Age-Related Diseases
Dr. Nina Strankaja
A medical doctor and clinical researcher at Haerle University Hospital in Denmark
Haerle University Hospital
Episode: Influence of Macrotroponin on the 99th Percentile Threshold in 2 High-Sensitivity Cardiac Troponin Assays

Host

Bob Barrett
Host of a show focused on advancements in clinical laboratory practices and research.

Reviews

4.3 out of 5 stars from 58 ratings
  • Clinical chem

    Amazing podcast on biochemistry...great for physicians and graduate students!

    Apple Podcasts
    5
    The-Thingi
    United States10 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners appreciate the quality of topics discussed, highlighting the importance for both physicians and graduate students in the field. The content is often described as engaging and informative, particularly suited for professionals focused on clinical chemistry advancements and practices.

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Talking Points

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Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Q: What would be the ideal outcome of your study and what's next?
The ideal outcome would be to change guidelines for NIPT testing and implement the mosaic ratio concept in clinical practice to alleviate stress for expectant parents.
Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Q: Is this mosaic ratio something that only your lab can calculate, or can your results be generalized to other NIPT assays?
Our findings are broadly generalizable and provide a roadmap for other labs to calculate a similar metric using open-source methods.
Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Q: Doctor, your study's central finding revolves around what you call digital estimates of trophoblastic mosaicism. This sounds technical. Can you break that down for our listeners and explain how this new approach can make NIPP better?
Digital estimates of trophoblastic mosaicism allow us to calculate the proportion of affected placental cells, significantly improving screening by helping reduce unnecessary invasive procedures.
Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Q: Your study uses a whole genome NIPT method, which can look beyond the common trisomies and detect sex chromosome abnormalities and other rare anomalies. What is the impact of finding these additional issues? Does it truly improve screening for patients?
Expanding the scope of screening has benefits and challenges, but our data show that tests for sex chromosome abnormalities can serve as a screening tool.
Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Q: So, Dr. Martens, can you comment on the advantages of non-invasive prenatal testing, or NIPT, over conventional screening?
NIPT has a much higher sensitivity and a dramatically lower false positivity rate compared to conventional screenings.

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Frequently Asked Questions About Clinical Chemistry Podcast

What is Clinical Chemistry Podcast about and what kind of topics does it cover?

Focused on the intersection of clinical chemistry and innovative medical practices, this podcast features in-depth discussions with experts in the field regarding recent research and advancements. Episodes cover critical topics such as machine learning applications in healthcare, cardiovascular diagnostics, and the disparities in diagnostic technologies across different populations. A unique aspect of this podcast is its emphasis on translating complex scientific research into practical applications in clinical settings, making it a valuable resource for professionals in laboratory medicine and healthcare innovation.

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Which podcasts are similar to Clinical Chemistry Podcast?

These podcasts share a similar audience with Clinical Chemistry Podcast:

1. Science Magazine Podcast
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How many episodes of Clinical Chemistry Podcast are there?

Clinical Chemistry Podcast launched 14 years ago and published 1074 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Clinical Chemistry Podcast?

Recent guests on Clinical Chemistry Podcast include:

1. Dr. Garrett Martens
2. Dr. Nicholas Larky
3. Dr. Walter Craft
4. Dr. Osna Arsund
5. Dr. Joshua Lieberman
6. Dr. Yixin Chang
7. Dr. Hans Lilje
8. Dr. Jesse Sigmiller

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