ATGC doctors' chat
雅娴，莲燕，王祎是由两位生物医药领域的科研工作者发起的聊天类播客。我们关注生命如何走到今天，以及如何让ta更好。 商务合作：zyx3200@163.com
| Publishes | Monthly | Episodes | 64 | Founded | 4 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | ScienceLeisure | |||
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Latest Episodes
2026 年 5 月底，一项名为 RESolute 302 的三期临床试验结果登上了 ASCO 压轴场。10 多年来，胰腺癌的中位总生存期，都卡在 6 个月出头，而一款叫做 Daraxonrasib 的新药，把这个数字拉到了 13.2 个月——死亡风险下降了 60%。
为什么这件事如此震撼？因为它攻克的靶点叫做 KRAS——一个 1982 年就已被发现、与三成人类癌症相关、在胰腺癌中突变率接近 95%，却被整个科学界宣判了近 40 年"不可成药"的基因。这期节目里，我们聊了聊 RAS 蛋白到底... more
SSRI，全称 selective serotonin reuptake inhibitor，中文叫做选择性血清素再摄取抑制剂，是目前全球使用最广泛的抗抑郁药物。百忧解、左洛复、来士普，这些名字你可能不陌生。仅在美国，2023年就有约11.4%的成年人在服用抗抑郁药物处方。在全球抗抑郁药市场中，SSRI 占据了超过55%的份额，市场规模在2024年达到187亿美元，而且还在持续增长。
这类药物之所以能走到今天的位置，背后有一个支撑它的理论——「血清素假说」，也就是抑郁症是因为大脑里的血清素不足... more
这期节目的起点是人类学家 Helen Fisher 的著作《我们为什么相爱》，我们打开大脑，问一个更底层的问题：当我们爱上一个人，神经里究竟发生了什么？
原来，浪漫爱的底层驱动不是快乐，而是渴望——多巴胺的工作是让你"想要"，而不是让你"享受"。分手时经历的不只是情绪，而是真实的戒断反应，包括身体上的疼痛。
你会在这期听到：草原田鼠和山地田鼠为什么是动物界的"模范夫妻"和"渣男"？间歇性随机奖励为什么比稳定的爱更容易上瘾？以及失恋后为什么"越想停止反思、越停不下来"？
【时间轴】
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这期我们想聊一个离我们还有点距离、但每个女性都绕不开的话题——更年期。我们意识到一个很奇怪的事实：关于怀孕有无数本指导手册，关于青春期有无数的教育，但关于更年期这个占据女性一生 1/3 时间的阶段，几乎没有人告诉你会发生什么。「更年期」在社会中几乎是隐形的，但我们想在真正进入那个阶段之前，先作为旁观者把它看清楚。作为女性，我们在未来必然会经历什么？如果我们的身体变得不像年轻时那么「好用」，我们该做些什么？
这期节目的主线是一本书——《更年期，不是忍忍就好》（ Hot and Bothered）... more
Reviews
- 我与科研谈了10年
我与科研也快谈了6年了，主持人所谈的顾虑与选择都是我当下的迷茫点，然而主持人好的一点。起码有个喜好种子，然而我还没有找到这个种子
Apple Podcasts5箱魨大大
China2 years ago - 太棒了
生物狗每期必听
Apple Podcasts5ID：465317
United States2 years ago
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Apple Podcasts | #205 | China/Leisure |
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| Listeners per Episode | Gender Skew | Location | |||
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| Interests | Professions | Age Range | |||
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ATGC doctors' chat launched 4 years ago and published 64 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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