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Artwork for Aging-US
Aging
Cancer
Biological Aging
Covid-19
DNA Methylation
Idiopathic Pulmonary Fibrosis
Methylation Platforms
Osteoporosis
Telomere Shortening
Age-Related Diseases
Cardiorespiratory Fitness
Physical Fitness
Midlife Age Acceleration
Senescent Cell-Derived Vaccines
Targeted Cancer Therapy
Parkinson's Disease
Cell Death
Immune Pathways
Sarcopenia
Oxidative Stress

Aging-US is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease. Read ... more

PublishesDailyEpisodes500Founded5 years ago
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Science

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Artwork for Aging-US

Latest Episodes

BUFFALO, NY — September 24, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 7, 2025, titled, “What is the clinical evidence to support off-label rapamycin therapy in healthy adults?” In this study, led by Jacob... more

BUFFALO, NY — September 23, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 7, 2025, titled “Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence ... more

BUFFALO, NY — September 18, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled “The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity.” In this study,... more

BUFFALO, NY — September 16, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 6, 2025, titled “Age-related trends in amyloid positivity in Parkinson’s disease without dementia.” In this study, led by first author... more

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Recent Guests

Dr. Andres Cardenas
Assistant Professor in the Department of Epidemiology and Population Health at Stanford University
Stanford University
Episode: Longevity & Aging Series (S3, E5): Dr. Andres Cardenas
Han Li
Guest editor, internationally recognized leader in senescence and aging research.
Episode: Call for Papers: Commemorative Collection Honoring Dr. Judith Campisi
Irina Conboy
Guest editor, internationally recognized leader in senescence and aging research.
Episode: Call for Papers: Commemorative Collection Honoring Dr. Judith Campisi
David Gems
Leading scientist in the field of aging research
Episode: Call for Papers: Special Collection Honoring Dr. Mikhail (Misha) Blagosklonny
Dr. Julia Sidorova
Research Associate Professor in the Department of Pathology at the University of Washington
University of Washington
Episode: Longevity & Aging Series (S3, E2): Dr. Julia Sidorova
Yu-Xuan Lyu
Corresponding author from Southern University of Science and Technology
Southern University of Science and Technology, Shenzhen
Episode: Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging
Alex Zhavoronkov
Corresponding author from Insilico Medicine AI Limited
Insilico Medicine AI Limited, Abu Dhabi
Episode: Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging
Morten Scheibye-Knudsen
Corresponding author from the Center for Healthy Aging, University of Copenhagen
University of Copenhagen
Episode: Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging
Daniela Bakula
Corresponding author from the Center for Healthy Aging, University of Copenhagen
University of Copenhagen
Episode: Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging

Host

Josh Mitteldorf
Host and author

Reviews

4.6 out of 5 stars from 5 ratings
  • The reader

    I highly recommend the reader practice reading the paper summaries before recording. Additionally, listening to this podcast feels similar to listening to a radio ad read.

    Apple Podcasts
    3
    tuckjosh
    United States3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners appreciate the focus on scientific integrity and the exploration of cutting-edge research in aging and health, though some feedback suggests enhancing the clarity of complex topics for broader accessibility.

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Talking Points

Recent interactions between the hosts and their guests.

Longevity & Aging Series (S3, E5): Dr. Andres Cardenas
Q: What do we currently know about the effect of environmental chemical exposures on aging?
Smoking is a well-studied risk factor, but there is a need to explore other significant exposures like air pollution and chemical contamination.
Longevity & Aging Series (S3, E5): Dr. Andres Cardenas
Q: What is the main message of this paper?
Environmental exposures significantly affect aging trajectories, with chemical exposures having large effects on disease susceptibility.
Longevity & Aging Series (S3, E4): Dr. Shubhankar Suman
Q: What differences do you see between tumors in humans and those in mouse models?
Mouse tumor development differs as they tend to develop mainly in the small intestine rather than in the colon and rectum, which we see in humans.
Longevity & Aging Series (S3, E4): Dr. Shubhankar Suman
Q: What inspired the study and what led you to explore scenalytics like ABT-263?
The study was aimed at developing a proof of concept for using a senolytic or xenotherapeutic agent to mitigate radiation-induced late effects, including cancer.
Longevity & Aging Series (S3, E3): Dr. Stephen Vatner
Q: Do you think RGS14 gene therapy could be used to improve health and longevity?
Yes, Dr. Vatner believes gene therapy could be developed alongside pharmacological agents derived from the RGS14 knockout brown adipose tissue.

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Frequently Asked Questions About Aging-US

What is Aging-US about and what kind of topics does it cover?

Exploring the intersections of aging and health, this series focuses on cutting-edge research regarding age-related diseases, particularly cancer. Through expert interviews and discussions, it highlights significant discoveries in the biology of aging, novel preventive strategies, and the impact of lifestyle on longevity. Noteworthy topics include the analysis of aging mechanisms, the effectiveness of various anti-aging interventions, and insights into pioneering treatments that may slow down aging and improve health outcomes in older populations. This series is distinctive for its rigorous scientific approach combined with accessible discussions on complex topics surrounding aging, making it suitable for both professionals and non-experts ... more

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Which podcasts are similar to Aging-US?

These podcasts share a similar audience with Aging-US:

1. ZOE Science & Nutrition
2. Up First from NPR
3. The Dr. Joy Kong Podcast
4. The Daily
5. Today, Explained

How many episodes of Aging-US are there?

Aging-US launched 5 years ago and published 500 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Aging-US?

Recent guests on Aging-US include:

1. Dr. Andres Cardenas
2. Han Li
3. Irina Conboy
4. David Gems
5. Dr. Julia Sidorova
6. Yu-Xuan Lyu
7. Alex Zhavoronkov
8. Morten Scheibye-Knudsen

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