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Artificial Intelligence
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Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is ... more

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Artwork for What's Your Problem?

Latest Episodes

Throughout the next few weeks, every Monday we'll be sharing some of our favorite episodes from Jacob's other show Business History. We hope you enjoy them and if you want to hear more, subscriber to Business History on Apple, Spotify or wherever you... more

Circadian rhythm isn’t just controlled by your brain. Every cell in your body runs on a 24-hour cycle, including your muscle cells.

Karyn Esser is the chair of the department of physiology and aging at the University of Florida, and she’s a leadin... more

Throughout the next few weeks, every Monday we'll be sharing some of our favorite episodes from Jacob's other show Business History. We hope you enjoy them and if you want to hear more, subscriber to Business History on Apple, Spotify or wherever you... more

Note: Today’s show is sponsored by PayPal.

Kartik Hosanagar is a professor at the Wharton School. The problems he studies include: What will it take for people to trust AI agents to buy stuff for them? And how should businesses prepare for a world ... more

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Recent Guests

Karyn Esser
Chair of the Department of Physiology and Aging and circadian rhythm researcher
University of Florida
Episode: Every Cell in Your Body Has a Clock
Kartik Hosanagar
Professor of Operations and Marketing at the Wharton School
The Wharton School
Episode: Solving the Trust Problem in AI Shopping
Jason Ballard
Co-founder and CEO of Icon
Icon
Episode: Can a Robot Build Better, Cheaper Houses?
Max Spero
CEO and co-founder of Pangram
Pangram
Episode: Did AI Write This?
Luke Aragoni
Co-founder and CEO of Lodi (Likeness on the Internet)
Lodi
Episode: Can We Defeat Deepfakes?
Zvi Mosiewicz
AI writer and commentator on AI risks
Don't Worry About the Vase (substack)
Episode: Should We Pause AI?
Christine Chase
Vice President, Financial Consultant at Fidelity Investments
Fidelity Investments
Episode: Bonus: Planning for Your Financial Future
Saif Khawaja
CEO and co-founder of Shinkai
Shinkai
Episode: Can a Robot Kill Fish Humanely?
Catherine Nakalembe
Assistant Professor at the University of Maryland; Africa Program Director at NASA Harvest
NASA Harvest / University of Maryland
Episode: Using Satellites to Prevent Famines

Host

Jacob Goldstein
Host of the show?

Reviews

4.6 out of 5 stars from 604 ratings
  • No problem!

    Jacob is one of the most skillful interviewers I listen to. He asks the tough questions with a light of touch, always respectful but never settling for b.s. answers. One of my favorite podcasts!

    Apple Podcasts
    5
    J. Boher
    United States2 months ago
  • Delete the Process, Crash the Car

    The advertisements are annoying, frequent and blaring.

    Interesting topic but turned off when it was revealed the guest was an Elon Musk fan. Sure it’s possible to work faster but when it comes to public safety this can result in cars that crash and kill people, rockets that crash land in areas where rockets shouldn’t crash. Then there is what was done to Twitter and to democracy and government. Very broken and toxic. Delete the process, demolish the rose garden.

    Musk is also a liar who said he ... more

    Apple Podcasts
    1
    acuteangle
    Australiaa year ago
  • Good, but...

    You have really good content. BUT, you like, can't speak an entire like sentence without like using really distracting like language. Like grow up and learn how to like speak. Your language is like way too like distracting

    Apple Podcasts
    3
    disappointed 206
    United Statesa year ago
  • Love the podcast...... Jacob covers lots of interesting topics and the length of the episodes are perfect for when I'm out walking. The only reason I didn't give it 5 stars is the amount of commercials. I get it, you have to generate income to finance the podcast, but a recent episode i listened to had almost 10 minutes of commercials in the 28 minute length.

    Podcast Addict
    4
    kathyaj
    a year ago
  • Fantastic

    Jacob, come on, Nan kept explaining that their climate capture strategy is the opposite of a marginal investor (they are a first mover investor at much higher than marginal cost ) and you kept repeating marginal several times!

    Apple Podcasts
    5
    Charly358
    United Kingdoma year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some listeners critique interview style as interruptive but improvements are noted.
Listeners praise the show's breadth and practical insights across technology and policy.
Guests consistently bring actionable context and clear explanations of complex topics.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#118
United States/Technology
Apple Podcasts
#108
Canada/Technology
Apple Podcasts
#173
United Kingdom/Technology
Apple Podcasts
#71
Australia/Technology
Apple Podcasts
#73
Singapore/Technology
Apple Podcasts
#77
Ireland/Technology

Talking Points

Recent interactions between the hosts and their guests.

Every Cell in Your Body Has a Clock
Q: Does it matter what time of day I exercise?
For general health, the most important thing is to exercise and find a routine that works. For performance, training around the time of an event may help the body be better prepared.
Every Cell in Your Body Has a Clock
Q: What happens to the circadian rhythm in muscle cells as we age, and how can we keep the system from falling apart?
The clock's timer continues working, but its output becomes less orderly with age, changing which genes are regulated and when. Exercise improves clock function and its output across multiple organs, supporting resilience and recovery.
Solving the Trust Problem in AI Shopping
Q: If you're a small company, what should you do?
Hosanagar recommends making a strategic choice between offering an exceptional human shopping experience and building a dedicated strategy for AI agents, including research into how they interpret and rank information.
Solving the Trust Problem in AI Shopping
Q: What has to happen to get to the point where consumers trust agents to buy stuff on their behalf?
Hosanagar says the technology and supporting infrastructure must work, consumers need to change their behavior, and platforms must protect customers by taking responsibility for unauthorized or unintended purchases.
Did AI Write This?
Q: How do watermarks compare to Pangram's approach?
Watermarks provide a binary signal of whether AI contributed at some level, but Pangram offers a more granular assessment of the degree of AI assistance and can handle broader detection scenarios beyond watermark presence.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About What's Your Problem?

What is What's Your Problem? about and what kind of topics does it cover?

Across recent episodes, rigorous experts and ambitious founders discuss how technology, policy, and entrepreneurship collide to tackle big problems—from aging biology and AI in medicine to 3D mapping, lunar economies, and climate solutions. Conversations mix practical deployments (home robotics, AI agents, phage therapy) with systemic questions about education, labor markets, and global competition, often highlighting the human side of ambitious tech—trust, governance, and the storytelling needed to turn breakthroughs into real-world impact. A notable strength is the breadth: interviews span biotech, AI, space, agriculture, and energy, always centering how thoughtful experimentation and pragmatic business sense can move society forward. The... more

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Which podcasts are similar to What's Your Problem??

These podcasts share a similar audience with What's Your Problem?:

1. Business History
2. Planet Money
3. The Indicator from Planet Money
4. Freakonomics Radio
5. The Economics of Everyday Things

How many episodes of What's Your Problem? are there?

What's Your Problem? launched 5 years ago and published 222 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on What's Your Problem??

Recent guests on What's Your Problem? include:

1. Karyn Esser
2. Kartik Hosanagar
3. Jason Ballard
4. Max Spero
5. Luke Aragoni
6. Zvi Mosiewicz
7. Christine Chase
8. Saif Khawaja

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