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Artwork for The Lee and Irene Show

The Lee and Irene Show

Lee Holmes
Gut Health
Ultra-Processed Foods
Cleaning
Sunscreens
Chocolate Industry
Collagen
Cost Of Living Crisis
Japan
Sugar
Mediterranean Diet
Chiropractors
Yoga
Gut Health (prebiotics and Probiotics)
Sugar and Substitutes
Palm Beach, Australia
Eat To Heal
_insomnia
Michele Chevalley-Hedge
Chronic Inflammation
Cbt-I

WELCOME to The Lee and Irene Show! 🎙️ Lee Holmes and Irene Falcone bring you real, raw, and refreshingly honest chats about wellness, beauty and life, minus the woo-woo. We’re here to keep wellness human, hilarious, and totally unfiltered. theleeandireneshow.substack.com

PublishesWeeklyEpisodes17Founded4 months ago
Number of ListenersCategories
Health & FitnessNutrition

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Artwork for The Lee and Irene Show

Latest Episodes

Episode 17: Lyme Disease, Being Gaslit, and Getting Your Mojo Back - Amy Down's Four-Year Fight to Be Believed 🩺

Amy Down spent four years being told there was nothing wrong with her. Exhausted, foggy, gut in revolt, running on adrenaline while rai... more

This week’s guest has an answer for that, and it is not the one anyone expects.

Kate Kendall has been teaching yoga in Australia for over two decades. She is the co-founder of Flow Athletic in Sydney, the author of Life in Flow, and the woman behind... more

This week’s guest could not be more fitting. Dr. Amelia Scott is a clinical psychologist, sleep researcher, and the founder of Circa Sleep, and she walks Lee and Irene through something both hosts have lived but never had language for: the cycle of i... more

Show Notes: Episode 14

The Lee and Irene Show

Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.

Lee has written twelve books, and this one might b... more

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Recent Guests

Kate Kendall
Co-founder of Flow Athletic; author and yoga/mindfulness teacher
Flow Athletic; Author
Episode: Episode 16: Has Reformer Pilates Eaten Yoga? Kate Kendall Settles It and We Talk GLP1s.
Amelia Scott
Clinical psychologist, sleep researcher, PhD, founder of Circa Sleep
Circa Sleep
Episode: Episode 15: Why Trying Harder to Sleep Is Keeping You Awake, with Sleep Psychologist Dr. Amelia Scott.
Jane Papalia
Qualified naturopath, clinical nutritionist, founder of The Mediterranean Naturopath
Mediterranean Naturopath
Episode: Episode 13, Naturopath Jane Papalia on the Mediterranean Diet, Longevity, Beauty, and Why Your Nonna Was Probably Right All Along, Wayne Gets ‘Splained on Reflux and Irene Busts Out a Rant
Michele Chevalley-H Hedge
Clinical nutritionist, author and health educator
Author of Beating Sugar Addiction for Dummies; The Australian Healthy Hormone Diet; Eat, Drink and Still Shrink
Episode: Episode 12 All Hail the Sugar and Energy Queen Michele Chevalley-Hedge, and the Labels That Are Lying to You, Justin Finally Learns to Breathe, and Lee’s Rant on the Fillers Nobody Warned You About.
Mason Taylor
Mushroom maven, founder of SuperFeast
SuperFeast
Episode: Episode 10: Mason Taylor on Mushrooms & the Ancient Art of Not Falling Apart, Justin is in a Bit of a Pickle, and Irene’s Forever Rant About Forever Chemicals. 🍄
Justin Smidmore
Editor/Technical Support
Clean Nectarine / Supercharged Food
Episode: Episode 9: Irene’s Everything Shower, Justin Tries to Win Over a One-Eyed Cat, and Lee Can’t "Liver" Without This. 🍯
Amelia Phillips
Nutritionist and exercise scientist
Independent nutrition/exercise science professional
Episode: Episode 8: Amelia Phillips unpacks the calories conversation, Justin gets schooled on friendships and Lee rants about green powders.
Di Edwards
Guest from Over the Back Fence podcast
Over the Back Fence
Episode: Episode 4: From Tree-Hugging to Biohacking Bros, 40 Year Friendships and the Truth About Living Forever 🎙️
Nicola Dale
Guest from Over the Back Fence podcast
Over the Back Fence
Episode: Episode 4: From Tree-Hugging to Biohacking Bros, 40 Year Friendships and the Truth About Living Forever 🎙️

Hosts

Lee Holmes
Host of wellness and lifestyle discussions; co-creator of the show; wellness author.
Irene Falcone
Co-host with a focus on wellness education and practical guidance.

Reviews

4.9 out of 5 stars from 11 ratings
  • New Fav pod

    Love this podcast with Lee & Irene - smart - funny and learning a lot . Highly recommend

    Apple Podcasts
    5
    size34T
    Australia2 months ago
  • My favourite new podcast

    I love Wellness Unfiltered with Lee and Irene.

    Its a refreshing, honest take on modern wellness that cuts through the noise and gets to what actually matters. Rather than recycling trends or pushing fad ideas.

    Lee and Irene bring a grounded, thoughtful humorous ,perspective that feels both intelligent and deeply human.

    What makes this podcast stand out is the balance between evidence-based insight and real life (lived) experience. Looking forward to the next episodes!

    Apple Podcasts
    5
    Roxie reviews
    Australia3 months ago
  • Dynamic Duo!!

    What fabulous, interesting and informative discussions on very relevant topics! Lee and Irene do such a great job at unraveling the mixed messaging often in the media and keep it interesting, fun and educational! Love this new podcast! 👏

    Apple Podcasts
    5
    Pia N Larsen
    Australia4 months ago
  • Plug free and fun info

    Plug free wellness info finally. Also I trust Irene and Lee to tell it like it is.

    Apple Podcasts
    5
    justin Smidmore
    Australia4 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Thoughtful, evidence-based yet practical wellness discussions.
Plug-free, honest wellness conversations that feel real.
Great host dynamic; informative without hype.
Clear, human approach with grounded take on trends.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Episode 14: Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.
Q: What role does trauma play in inflammation, and how can someone address it in a practical way?
Trauma and chronic stress can keep the nervous system in a state of fight-or-flight, impairing digestion and promoting inflammation. Healing involves nervous system regulation, sleep, routines, and compassionate self-care in addition to dietary changes.
Episode 14: Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.
Q: How does the 4321 Map Approach help people eat for inflammation in a real-world way?
The map provides a flexible, non-restrictive template to crowd in healthy foods while maintaining balance, with emphasis on gut health, blood sugar control, and practical, tasty recipes that fit into daily life.
Episode 14: Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.
Q: Can you explain SPMs and how they differ from traditional anti-inflammatory approaches?
SPMs are pro-resolving mediators produced from omega-3s that help clear inflammatory debris and promote tissue regeneration, returning the body to homeostasis rather than simply blocking inflammation.
Episode 14: Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.
Q: What are senescent (zombie) cells, and why do they matter for aging and inflammation?
Senescent cells are cells that stop functioning but don't die, releasing inflammatory signals that disrupt surrounding tissue. Periodically clearing these cells can slow biological aging and reduce inflammation.
Episode 14: Lee Holmes Launches Her 12th Book “Eat to Heal”, the Truth About Chronic Inflammation and Zombie Cells, and Justin Gets 'Splained on Low Testosterone.
Q: What inspired you to write Eat to Heal and focus on inflammation as a central theme?
Lee explains that food as medicine, particularly in relation to chronic inflammation, became a central thesis after years of clinical observation and research. She emphasizes practical, non-judgmental guidance that people can implement to slow aging and reduce disease.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
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Professions
Age Range
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Frequently Asked Questions About The Lee and Irene Show

What is The Lee and Irene Show about and what kind of topics does it cover?

The show offers practical, down-to-earth conversations about wellness, nutrition, beauty, and daily life, guided by two hosts who mix personal stories with evidence-based insights. Across episodes, topics swing between nutrition science, gut health, sleep, aging, and real-world wellness hacks, all filtered through a skeptical-but-supportive lens. Notes often highlight the balance between science and lived experience, with guests ranging from nutritionists and naturopaths to chefs and mindfulness teachers. A standout aspect is the candid, humorous banter that keeps complex wellness concepts approachable, plus a willingness to question trends and spotlight consumer literacy. This mix makes it useful for listeners who want practical health gui... more

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Which podcasts are similar to The Lee and Irene Show?

These podcasts share a similar audience with The Lee and Irene Show:

1. Diet Notes with Susie Burrell
2. Life Uncut
3. No Filter
4. Unleashed
5. Lise and Sarah

How many episodes of The Lee and Irene Show are there?

The Lee and Irene Show launched 4 months ago and published 17 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Lee and Irene Show?

Recent guests on The Lee and Irene Show include:

1. Kate Kendall
2. Amelia Scott
3. Jane Papalia
4. Michele Chevalley-H Hedge
5. Mason Taylor
6. Justin Smidmore
7. Amelia Phillips
8. Di Edwards

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