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Two guys talking **it - A Gastroenterology and Hepatology podcast

A/Prof Jon Segal and Dr James Haridy
Gastroenterology
Irritable Bowel Syndrome
Coeliac Disease
Gut-Brain Interaction
Inflammatory Bowel Disease
Hepatology
Amitriptyline
Clinical Trials
Bile Acid Diarrhea
Low FODMAP Diet
Podcast
Checkpoint Inhibitor Colitis
Meta-Analysis
Cognitive Behavioral Therapy
Psychological Therapies
Psychosomatic Disorders
Primary Sclerosing Cholangitis
Autoimmune Hepatitis
Glp-1 Agonists
Checkpoint Inhibitor Hepatitis

“Two Guys Talking $#it” is a podcast where two Gastroenterologists break down complex topics into engaging, educational, and occasionally humorous conversations. From liver health to gut microbiota and everything in between, A/Professor Jonathan Segal and Dr James Haridy deliver insights, share the latest research, and discuss clinical pearls with the odd guest in tow. Comments, suggestions, quest... more

PublishesMonthlyEpisodes13Founded2 years ago
Number of ListenersCategories
MedicineHealth & Fitness

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Latest Episodes

We're back for Season 2, and Jon and James kick things off with one of their favourite topics: Incretin mimetics. The gut is the biggest endocrine organ in the body, and the data in steatotic liver disease is now as good as anything we have in Hepato... more

We're back. After a longer-than-planned hiatus involving life, work, and the general chaos of being two busy clinicians: Two Guys Talking $#it is returning for Season 2.

The spark? Jon got stopped in a hospital corridor by a non-gastro colleague who... more

Today we had the privilege of talking to a true superstar in the world of Hepatology.

Elliot B. Tapper MD is an Associate Professor in the Division of Gastroenterology and Hepatology at the University of Michigan. He is Academic Chief of Hepatology.... more

Today we’re talking bugs, bowels, and breakthroughs with A/Prof Gianluca Ianiro and Dr. Ben Mullish, two microbiome maestros who make poo science strangely fascinating.

A/Prof Gianluca Ianiro is an Associate Professor of Gastroenterology at the Univ... more

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Recent Guests

Elliot Tapper
Associate Professor of Medicine and Academic Chief of Hepatology at the University of Michigan, expert in Chronic Liver Disease
University of Michigan
Episode: #11: A/Prof Elliot Tapper - Liver legends, lies and lactulose
Gianluca Ianiro
Gastroenterologist and leading figure in microbiome research, focused on moving the microbiome field forward
Gastroenterology researcher and clinician (Rome, Italy)
Episode: #10: A/Prof Gianluca Ianiro and Dr Benjamin Mullish - The gut microbiome in health and disease
Benjamin Mullish
Consultant gastroenterologist with expertise in microbiome research and liver disease
St Mary's Hospital and Imperial College
Episode: #10: A/Prof Gianluca Ianiro and Dr Benjamin Mullish - The gut microbiome in health and disease
Gideon Hirschfield
Hepatologist, expert in autoimmune liver disease
University of Toronto
Episode: #08: Professor Gideon Hirschfield - The Art and Science of PSC and Autoimmune Hepatitis
Cynthia Kanagasundaram
A consultant gastroenterologist from the UK
Luton and Dunstable Hospital
Episode: #05: A/Professor Jason Tye-Din - Coeliac Disease unpacked: Diagnosis, treatment and emerging approaches
Professor Alex Ford
Consultant gastroenterologist and professor at the University of Leeds specializing in disorders of gut-brain interaction
University of Leeds
Episode: #04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS

Hosts

Jonathan Segal
A/Professor of Gastroenterology with an interest in inflammatory bowel disease and a penchant for engaging educational discussions.
James Haridy
Dr. of Gastroenterology with expertise in liver health and a passion for clinical education and patient management.

Reviews

4.8 out of 5 stars from 35 ratings
  • Needs Work

    Flat and monotonous at times

    Apple Podcasts
    1
    Joe Richard Head
    Australia10 months ago
  • Great listen for GI docs

    In the era of multiple podcasts from societies, journals, most of which are hard to listen to, this one does a nice job of discussing important topics, and getting experts to give their opinions. Keep going gentlemen!!! I am a fan!

    Apple Podcasts
    5
    GI-pearls
    United Statesa year ago
  • Love it!

    I love your podcast, please keep up the good work!

    Apple Podcasts
    5
    Zhlobster Mobster
    Australiaa year ago
  • Could be better

    There are better podcasts out there.

    Apple Podcasts
    2
    Ollie_Sm
    Australiaa year ago
  • Top top podcast

    These are a great listen. Insightful questions and clinically applicable answers. Golden nugget after golden nugget! Doing fantastic work James and Jon, as are your guests

    Apple Podcasts
    5
    Phil Oppong
    United Kingdoma year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some listeners feel there are better podcasts available, suggesting a desire for even higher quality discussions.
Listeners appreciate the engaging and educational style of the conversations, highlighting how complex topics are presented in an accessible manner.
Overall, positive feedback centers around the comedic yet informative approach taken by the hosts, making challenging subjects more relatable.
The podcast is praised for delivering insightful content that remains clinically applicable, often featuring expert guests to deepen the discussions.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

#11: A/Prof Elliot Tapper - Liver legends, lies and lactulose
Q: How did Elliot Tapper start using Tweetorials and does he think it changes clinician behavior?
He began by tweeting papers to learn and later shifted to highlighting others' work, which broadened the community and improved knowledge sharing; he believes social media can influence learning and practice, but cautions about missteps and the need for careful communication.
#13: Jon and James - GLP-1s: From Lizard spit to liver fibrosis
Q: What have the major trials shown about liver disease outcomes with these drugs, particularly MAFLD/MASH?
Phase 2 and phase 3 trials with semaglutide and tirzepatide show substantial MAFLD/MASH improvements, including resolution of steatohepatitis and fibrosis reduction in a meaningful proportion of patients, indicating these drugs can address liver pathology beyond weight loss.
#04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS
Q: What mistakes do you see commonly made in IBS diagnosis and treatment?
Common mistakes include treating IBS as a diagnosis of exclusion, misinterpreting causes such as SIBO, and viewing IBS as purely a psychological disorder, which delegitimizes the real pain and impact on quality of life.
#04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS
Q: Could you summarize for us what irritable bowel syndrome is?
IBS is a disorder of bowel function characterized by abdominal pain associated with altered bowel habits, emphasizing that there might be an underlying organic basis that hasn't been fully understood.
#02: Immune checkpoint colitis and hepatitis
Q: How would you treat checkpoint-related hepatitis?
Treatment typically starts with steroids, particularly for grades two and three.

Audience Metrics

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Frequently Asked Questions About Two guys talking **it

What is Two guys talking **it about and what kind of topics does it cover?

Engaging conversations focused on the field of gastroenterology and hepatology are at the heart of the content, with hosts bringing their expertise as gastroenterologists to simplify complex medical topics. Listeners can expect in-depth discussions about various conditions ranging from autoimmune liver diseases and coeliac disease to the gut-brain interaction in IBS. The podcast also offers insights into the latest research, treatment strategies, and patient management issues, while often featuring expert guests to provide additional perspectives. With a balanced mix of information and humor, the engaging format looks to entertain and educate a broad audience interested in gastrointestinal health.

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Which podcasts are similar to Two guys talking **it?

These podcasts share a similar audience with Two guys talking **it:

1. The Curbsiders Internal Medicine Podcast
2. The Clinical Problem Solvers

How many episodes of Two guys talking **it are there?

Two guys talking **it launched 2 years ago and published 13 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Two guys talking **it?

Recent guests on Two guys talking **it include:

1. Elliot Tapper
2. Gianluca Ianiro
3. Benjamin Mullish
4. Gideon Hirschfield
5. Cynthia Kanagasundaram
6. Professor Alex Ford

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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