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UnHack with Drex DeFord

This Week Health
Cybersecurity
Healthcare IT
Imposter Syndrome
Healthcare Technology
Privacy Breaches
Ransomware
Cyber Insurance
Change Healthcare
Data Breaches
The 229 Project
Healthcare
Return To Work Policies
Ascension Hack
Ransomware Attack
SOAR Conference
HHS Cybersecurity Regulations
Patient Engagement
Generative AI
Epic
Rural Hospitals

Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and te... more

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Latest Episodes

In a stunning betrayal of trust, two cybersecurity professionals—an incident response manager and a ransomware negotiator—pled guilty to operating as affiliates of the AlphaV/BlackCat ransomware gang. Between May and November 2023, they attacked five... more

January 19, 2026: Bill Russell, Drex DeFord, and Sarah Richardson unpack OpenAI's two major healthcare announcements that could fundamentally reshape how patients interact with their health data—and how health systems govern AI. ChatGPT Health promis... more

As healthcare organizations deploy AI agents across clinical, business, and research operations, we're creating a new class of insider threat—one that works 24/7, follows instructions perfectly, and moves at machine speed. Drexel explores why AI agen... more

January 12, 2026: Epic is defending three simultaneous lawsuits while CIOs grapple with vendors imposing staggering price increases—some as high as 600%. Bill, Sarah, and Drex tackle the uncomfortable truth about AI leadership: it's time to figure it... more

Drex breaks down ISC2's 2025 cybersecurity workforce study and explains why healthcare's security staffing problem isn't about finding more people—it's about broken operating models and unrealistic expectations. He covers the critical skills gap in t... more

January 6, 2026: Healthcare is transforming through connection, and 2026 promises to take that mission further than ever before. This Week Health is expanding its reach with 63 events across 30 cities, bringing healthcare leaders together for deeper ... more

January 5, 2026: ServiceNow's $7 billion acquisition of Armis signals a major shift in healthcare IT consolidation strategy. Jason Rose, CEO of Clearsense dives into what this deal means for health systems juggling overlapping security tools and bloa... more

December 29, 2025: As 2025 draws to a close, Drex, Sarah, and Bill gather to reflect on a year of struggles and triumphs. From unprecedented CIO turnover among top talent to the stark reality of workforce exhaustion, this candid conversation reveals ... more

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Recent Guests

Charles Knight
Founder and Managing Partner at EHC Consulting
EHC Consulting
Episode: Newsday: Preparing for Cloud Outages and Phishing Attacks with Charles Knight
Will Houston
Network Security Manager at Mount Desert Island Hospital.
Mount Desert Island Hospital
Episode: Solution Showcase: Pro Security In Your Pocket With Will Houston, Preston Duren, and Spencer Bales
Spencer Bales
Vice President of Product at Fortified Health Security.
Fortified Health Security
Episode: Solution Showcase: Pro Security In Your Pocket With Will Houston, Preston Duren, and Spencer Bales
Shawna Hofer
CISO at St. Luke's Health System in Boise, Idaho
St. Luke's
Episode: UnHack (the Podcast): Breaking Down Silos and Building Up Culture with Shawna Hofer
Dave Dyell
Principal at Innovative Consulting Group
Innovative Consulting Group
Episode: Newsday: Merger Madness and Why Hospitals are Moving Back to On-Prem Data with Dave Dyell
Kurt Telep
Healthcare Field CTO at Nutanix
Nutanix
Episode: Executive Interview: How Complexity Kills Innovation and Lasting IT Leadership with Kurt Telep
Preston Duren
Threat Services at Fortified Health Security
Fortified Health Security
Episode: Newsday: MFA Isn't Enough and Why Healthcare Can’t Just Hack Back with Preston Duren
Bill Willis
An expert in identity and access management with extensive experience in the field.
Idmworks
Episode: Executive Interview: Solving Healthcare's Identity Access Management Complexity with Bill Willis
Russell Teague
Cybersecurity expert and principal at Fortified Health Security
Fortified Health Security
Episode: Newsday: The Perfect Storm in Healthcare Cybersecurity: AI, Costs, and Risk with Russell Teague

Host

Drex DeFord
Drex DeFord is a seasoned healthcare CIO and strategist, known for his insights on cybersecurity and risk management in healthcare. He hosts discussions that break down complex topics for a wide healthcare audience, emphasizing the importance of collaboration in ensuring cybersecurity. His experience spans multiple leadership roles, focusing on integrating technology and security to enhance patient safety.

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Talking Points

Recent interactions between the hosts and their guests.

UnHack (the Podcast): Breaking Down Silos and Building Up Culture with Shawna Hofer
Q: What's something about being a health care CISO that most outsiders don't really understand about the job?
Shawna highlights that being a successful health care CISO requires strong relational skills and the ability to work collaboratively with diverse teams, adapting communication to different audiences.
UnHack (the Podcast): Breaking Down Silos and Building Up Culture with Shawna Hofer
Q: How are you all thinking about AI governance and data protection and risks that weren't there six months ago or five or six days ago?
Shawna explains they are embedding new AI governance into existing processes without creating entirely new ones, while also forming an AI governance body to oversee AI initiatives.
UnHack (the Podcast): Breaking Down Silos and Building Up Culture with Shawna Hofer
Q: Tell me about how you have been thinking about the culture built around cybersecurity?
Shawna discusses the importance of making security a shared responsibility through education and initiatives that involve staff at all levels, particularly through community engagement and collaboration.
Executive Interview: How Complexity Kills Innovation and Lasting IT Leadership with Kurt Telep
Q: If you could whisper one piece of advice in a CIO's ear about the future and how they can better engage with it, what would it be?
Focus on simplicity and choose platforms and tools that integrate well, leveraging the resources you already have.
Executive Interview: How Complexity Kills Innovation and Lasting IT Leadership with Kurt Telep
Q: For Healthcare IT teams, what's real right now and what's hype?
Healthcare organizations are likely to consume AI as a workload, using out-of-the-box solutions from existing vendors rather than developing their own AI models.

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Frequently Asked Questions About UnHack

What is UnHack about and what kind of topics does it cover?

Focusing on the critical intersection of cybersecurity and healthcare safety, episodes typically examine pressing challenges within the healthcare industry. Numerous topics relate to risk management and strategies for building resilience against cyber threats, which are increasingly sophisticated. Guests often include cybersecurity professionals and healthcare leaders, discussing various themes such as identity management, operational resilience, and the implications of emerging technologies like AI in driving efficiencies. This content is particularly relevant to those in healthcare roles who may not have a technical background but are engaged in ensuring patient safety through improved security practices. The discussions aim to empower a ... more

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UnHack launched 5 years ago and published 222 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on UnHack?

Recent guests on UnHack include:

1. Charles Knight
2. Will Houston
3. Spencer Bales
4. Shawna Hofer
5. Dave Dyell
6. Kurt Telep
7. Preston Duren
8. Bill Willis

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