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This Week in Virology

Vincent Racaniello
Covid-19
Measles
Vaccination
Public Health
Influenza
Vaccines
Sars-Cov-2
Long Covid
Virology
Hepatitis B
RSV
CDC
Polio
Immunology
Avian Influenza
Hepatitis B Virus
Ebola
Dementia
Phage Therapy
Norovirus

This Week in Virology is a netcast about viruses - the kind that make you sick.

PublishesDailyEpisodes104Founded18 years ago
Number of ListenersCategories
ScienceHealth & FitnessMedicine

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Artwork for This Week in Virology

Latest Episodes

TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America.

Hosts: Vincent ... more

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In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory Committee for Immunization Practices, We... more

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TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological tissues.

Hosts: Vincent Racani... more

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In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, new screwwor... more

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Key Facts

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Recent Guests

Mark Stenglein
CSU researcher in Microbiology, Immunology, and Pathology
Colorado State University
Episode: TWiV 1345: Rocky Mountain Virology High
Angela Bosco-Lauth
Virologist focusing on arboviruses and high-pathogen influenza; CSU
Colorado State University
Episode: TWiV 1345: Rocky Mountain Virology High
Rebekah Kading
Laboratory researcher studying mosquito-borne and bat-borne viruses; CSU
Colorado State University
Episode: TWiV 1345: Rocky Mountain Virology High
Tom Ksiazek
Virologist, University of Texas Medical Branch at Galveston
UTMB
Episode: TWiV 1339: Ebola up close with Tom Ksiazek
Karen Torghele
Author of Albert Sabin, The Life of a Polio Vaccine Pioneer
Episode: TWiV Special: Albert Sabin with Karen Torghele
John Dye
Director of Foundational Sciences at USAMRIID
US Army Medical Research Institute of Infectious Diseases
Episode: TWiV Special: Ebola virus and Andes virus with John Dye
Daniel Griffin
Clinical virology expert and frequent TWIV guest
Columbia University Irving Medical Center (as inferred from context)
Episode: TWiV 1330: Clinical update with Dr. Daniel Griffin
Jolene Ramsey
Texas A&M University researcher
Texas A&M University
Episode: TWiV 1327: Influenza viruses in the MIST
Rich Condit
Emeritus professor
University of Florida
Episode: TWiV 1327: Influenza viruses in the MIST

Hosts

Vincent Racaniello
Host of the show; prominent virologist and science communicator.
Kathy Spindler
Co-host / contributor; professor emerita with expertise in virology and science education.

Reviews

4.8 out of 5 stars from 3.6k ratings
  • HEAR HEAR!

    Vincent’s in the moment righteous indignation is always a pleasure. You are all of us, my man!

    Apple Podcasts
    5
    RB9AVS
    United States3 months ago
  • It was great, but it devolves into politics

    Please, show less political anger and emphasize more science. Don't turn into just another partisan show. Focus on convincing rather than scolding.

    Apple Podcasts
    3
    MaximumZed
    United States3 months ago
  • Fantastically informative podcast

    Huge thanks to Vincent and the team and guests who put so much effort into this platform! I learn so much and find the discussion engaging. I’m a microbiologist, trained as a bacterial specialist, but for nearly 2 decades I’ve been doing bacteriophage research and that’s my team’s focus (so I guess I’m a viral guy too now). I have learned a great deal from this podcast and have been led to some super-informative papers by it. Gargantuan kudos for the way the podcast addressed the COVID-19 p... more

    Apple Podcasts
    5
    Family shared - Nik
    United States5 months ago
  • Love the weekly clinical update!

    One of my favourite podcasts! I look forward to the clinical updates every weekend and love learning about all things virology.

    Apple Podcasts
    5
    isla-june
    Canada5 months ago
  • Great science based podcast

    I just recently discovered this podcast and I’m so glad I did! I love all the information and discussions. Science based and so interesting!

    Apple Podcasts
    5
    MN0724
    United States6 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some listeners wish fewer political angles and more science-focused discussion.
Guests and hosts are praised for depth, accessibility, and engaging banter.
Listeners appreciate the rigorous, evidence-based science and clear clinical updates.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#116
United States/Science
Apple Podcasts
#146
Canada/Science
Apple Podcasts
#74
Hong Kong/Science
Apple Podcasts
#134
Saudi Arabia/Science
Apple Podcasts
#153
Mexico/Science
Apple Podcasts
#167
Ukraine/Science

Talking Points

Recent interactions between the hosts and their guests.

TWiV 1344: Clinical update with Dr. Daniel Griffin
Q: Kathy asks if Shingrix cross-reacts with HSV-1 and whether HSV-1 reactivations declined after Shingrix; she also asks about potential future boosters.
Daniel explains there is likely no cross-reactivity with HSV-1 from the Shingrix vaccine, but immune activation could contribute to reduced HSV-1 activity; booster duration remains unknown and may depend on ongoing data, with consideration given to re-vaccinating based on prior vaccines and doctor's guidance.
TWiV 1345: Rocky Mountain Virology High
Q: Why is it important to study a broad range of viruses and hosts rather than focusing only on those with immediate human health implications?
Broad discovery builds a reservoir of knowledge that can later enable rapid responses to unexpected outbreaks and reveals fundamental biology that can inform safer, more effective interventions.
TWiV 1338: Clinical update with Dr. Daniel Griffin
Q: Mary also asks about the effectiveness of Paxlovid versus Zocova for treatment and how these compare to FDA-established data.
Paxlovid has strong FDA-supported data for treatment in eligible patients, whereas Zocova lacks equivalent US FDA-approved treatment data; in practice, Paxlovid is preferred for treatment when infection is confirmed.
TWiV 1338: Clinical update with Dr. Daniel Griffin
Q: Mary asks about whether testing for COVID should be required before starting Zocova for post-exposure prophylaxis and how to manage if symptoms develop.
The host explains that Zocova is used for prevention and that Paxlovid remains the treatment option for diagnosed COVID-19; testing may occur to confirm infection status, but the recommended pathway depends on the clinical scenario and regulatory indications.
TWiV 1340: Clinical update with Dr. Daniel Griffin
Q: So Vincent, is it fair to think of this as oral remdesivir?
The drugs are precursors to the same active polymerase inhibitor; remdesivir is IV with a prodrug that aids cellular entry, while obeldesivir is oral and activated differently, but the end target—RdRP inhibition—is similar.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About This Week in Virology

What is This Week in Virology about and what kind of topics does it cover?

A rigorously science-focused show that covers virology, infectious disease, and public health with a strong emphasis on current outbreaks, vaccine discussions, and real-world clinical updates. Across episodes, listeners get deep dives into viruses, transmission dynamics, fieldwork insights, and the interplay between ecology and human health, often featuring expert guests and in-depth analysis of papers and data. Notable strengths include clear clinical context, accessible explanations of complex concepts, and a willingness to tackle policy and public messaging, all while maintaining a light, conversational tone that keeps dense science approachable for a knowledgeable audience.

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How many listeners does This Week in Virology get?

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Which podcasts are similar to This Week in Virology?

These podcasts share a similar audience with This Week in Virology:

1. This Week in Virology
2. Immune
3. This Week in Microbiology
4. Infectious Disease Puscast
5. This Week in Parasitism

How many episodes of This Week in Virology are there?

This Week in Virology launched 18 years ago and published 104 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on This Week in Virology?

Recent guests on This Week in Virology include:

1. Mark Stenglein
2. Angela Bosco-Lauth
3. Rebekah Kading
4. Tom Ksiazek
5. Karen Torghele
6. John Dye
7. Daniel Griffin
8. Jolene Ramsey

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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