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The Uromigos

The Uromigos
Prostate Cancer
Bladder Cancer
PARP Inhibitors
Renal Cancer
Clinical Trials
Radiotherapy
Pembrolizumab
Metastatic Bladder Cancer
Kidney Cancer
ASCO GU 2024
Combination Therapy
PSMA PET Imaging
Adjuvant Therapy
TALAPRO II
BRCA
Nivolumab
Overall Survival
EV302 Study
Hormone Therapy
Salvage Radiotherapy

Broadcasting the latest developments in GU cancer Hosted by Brian Rini and Tom Powles Brian Rini MD is an Ingram Professor of Medicine (Hematology/Oncology), Vanderbilt-Ingram Cancer Center Tom Powles is the Director of Barts Cancer Centre, St Bartholomew's Hospital and Professor of Genitourinary Oncology, Queen Mary University of London

PublishesDailyEpisodes483Founded6 years ago
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MedicineHealth & Fitness

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Artwork for The Uromigos

Latest Episodes

Brian, Silke and Tom discusses the latest data and insights from ASCO GU 2026 across kidney, prostate, and bladder cancer, highlighting new therapies, trial results, and future directions in urologic oncology.

summary

This episode explores the latest advances in circulating tumor DNA (ctDNA) and urinary tumor DNA (utDNA) in bladder cancer management. Experts discuss how these biomarkers are transforming perioperative decision-making, prognosis, and person... more

This detailed discussion covers the latest phase three trial results in kidney cancer, focusing on LITESPARK 011: Belzutifan plus Lenvatnib versus Cabozantinib. Brian, Tom and Bob Motzer analyze efficacy, safety, and implications for treatment sequen... more

This in-depth discussion explores the latest advancements in adjuvant kidney cancer treatment, focusing on the recent phase 3 trial results of belzutifan combined with Pembrolizumab (LITESPARK-022), mechanistic insights, biomarker development, and fu... more

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Recent Guests

Evan Yu
Expert in prostate cancer treatment
Episode: Episode 480: ASCO GU 2026 - PEACE-3 and BRCAway Final OS Results
Sophie Gillison
Colleague of Brian and Tom discussing ASCO GU preview
Not specified
Episode: Episode 476: ASCO GU 2026 Preview
Karine Tawagi
Oncologist specializing in bladder cancer and a presenter at the Uromigos meeting.
Episode: Episode 474: Uromigos Shorts - IO-refractory Urothelial Cancer
David Einstein
Geomedical Oncologist and leader of the Geomedical Oncology Program
Beth Israel Deaconess Medical Center, part of Dana-Farber
Episode: Episode 473: Uromigos Shorts - EMBARK and BCR Prostate Cancer
David Aggen
Faculty at Memorial Sloan Kettering
Memorial Sloan Kettering
Episode: Episode 472: Uromigos Shorts - Variant Histology Bladder Cancer
Michael Morris
Section head of prostate cancer at Memorial Sloan Kettering Cancer Center
Episode: Episode 442: The History of ARPI Development in Prostate Cancer
Scott Tagawa
Presenter of the PSMA addition study
Cornell University
Episode: Episode 451: ESMO 2025 - PSMAddition
Chris Suarez
Researcher at Valhebron
Valhebron
Episode: Episode 446: ESMO 2025 - OPTIC and front-line RCC triplets
Christian Kollmannsberger
Medical oncologist and researcher in testis cancer treatments
Vancouver, Canada
Episode: Episode 438: The History of Testis Cancer Treatment

Hosts

Brian Rini
Co-host and expert in renal cell carcinoma, Professor of Cancer Research and Medicine at Vanderbilt-Ingram Cancer Center.
Tom Powles
Co-host and Director of Barts Cancer Centre, Professor of Genitourinary Oncology at Queen Mary University of London.

Reviews

4.8 out of 5 stars from 164 ratings
  • Excellent resource for patients anddocs

    The Uromigos keep patients and doctors informed with the very latest studies and research in urogenital cancer. I appreciate their hopeful, upbeat and revealing interviews with cutting edge researchers.

    Apple Podcasts
    5
    Tea Green
    United States5 months ago
  • Informative podcast

    This podcast is a one-stop shop for all things GU oncology. The information is balanced, up to date and relevant for anyone in this field

    Apple Podcasts
    5
    F93111111
    United Kingdom2 years ago
  • Great for staying up on GU oncology

    Drs. Powles and Rini are some of the most eminent current leaders in GU oncology. In this podcast, they discuss recent key studies in the field and really break down the key questions clinicians and patients want to know — are they clinically significant, will they change practice, and what are the next steps? Also, there are a lot of cheesy jokes which this humble listener somehow enjoys.

    Apple Podcasts
    5
    Attentive listener 12345
    United States2 years ago
  • Topical and interesting

    Great discussion of topical issues within the urology space from a engaging, experienced and knowledgeable group of oncologists.

    Apple Podcasts
    5
    Antman1805
    Australia3 years ago
  • Fantastic podcast

    This is a fantastic podcast! Great insight with provocative discussions (while keeping it lighthearted at the same time).... Thank you guys. Keep them coming....

    Apple Podcasts
    5
    Jacky4911
    United States5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners appreciate the informative nature of the discussions, citing it as an excellent resource for keeping up to date with advances in oncology. There are numerous compliments on the engaging delivery and depth of analysis provided by the hosts and their guests.
The blend of humor with serious topics has been positively received, making complex issues more accessible. Commenters have noted that the podcast is especially valuable for both patients wanting to understand their treatment options and healthcare professionals seeking to enhance their knowledge.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Episode 480: ASCO GU 2026 - PEACE-3 and BRCAway Final OS Results
Q: What can you tell us about the PEACE-3 trial results?
The PEACE-3 trial showed a median overall survival benefit for Enzalutamide plus Radium over Enzalutamide alone, confirming the efficacy of this combination in treating metastatic castration-resistant prostate cancer.
Episode 485: ASCO GU 2026 - LITESPARK 011: Len/Belzu vs Cabo
Q: Why should we be giving Len Belzutifan over Len Everolimus?
The combination with Belzutifan is better tolerated and offers more durable responses than giving Lenvatinib with Everolimus.
Episode 485: ASCO GU 2026 - LITESPARK 011: Len/Belzu vs Cabo
Q: What do you think of the interim analysis for overall survival and how it's trending?
The data is immature but currently favors Belzutifan plus Lenvatinib over Cabozantinib.
Episode 470: Bladder Cancer Year in Review
Q: Can you elaborate on the tolerability and safety of the therapies discussed?
The therapies were surprisingly well tolerated, with a high percentage of patients going on to receive surgery, and the safety profile aligned closely with expectations.
Episode 470: Bladder Cancer Year in Review
Q: What about adjuvant therapy?
The results for adjuvant EV Pembro are promising, but sticking closely to the protocol is essential until more trial results are in.

Audience Metrics

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Frequently Asked Questions About The Uromigos

What is The Uromigos about and what kind of topics does it cover?

The podcast provides in-depth discussions and analyses focusing on the latest developments in genitourinary (GU) cancer, featuring a combination of expert opinions and recent research findings. Topics range from advancements in treatment strategies for kidney, bladder, and prostate cancers to the implications of clinical trials and emerging therapies. The hosts, who are leading oncologists, often welcome guest experts to share insights, making complex medical developments accessible for both healthcare professionals and patients alike. The atmosphere is likely to be engaging yet informative, suitable for anyone interested in staying current within the oncology field.

With its emphasis on both clinical effectiveness and patient-centered care... more

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Which podcasts are similar to The Uromigos?

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1. EconTalk
2. The Ezra Klein Show
3. The Journal.
4. Freakonomics Radio
5. Political Gabfest

How many episodes of The Uromigos are there?

The Uromigos launched 6 years ago and published 483 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Uromigos?

Recent guests on The Uromigos include:

1. Evan Yu
2. Sophie Gillison
3. Karine Tawagi
4. David Einstein
5. David Aggen
6. Michael Morris
7. Scott Tagawa
8. Chris Suarez

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