Rephonic
Artwork for The Poison Lab
Toxicology
Poisoning
Cardiac Arrest
Morel Mushrooms
Naloxone
Mushroom Poisoning
Opioid Overdose
Emergency Medicine
Novel Psychoactive Substances
Aconite
Bozeman, Montana
Herbal Supplements
Gotta Pick Em
Fentanyl
American Heart Association Guidelines
Clinical Toxicology
Bromazolam
Toxic Shock Syndrome
PFAS
Medical Toxicology

Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical mana... more

PublishesTwice weeklyEpisodes94Founded6 years ago
Number of ListenersCategories
Life SciencesEducationScience

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Artwork for The Poison Lab

Latest Episodes

After weeks of investigation, the Bozeman outbreak is contained, but the questions it raised are much harder to close.

In the final episode of A Morel Dilemma, we return to Montana to understand how investigators traced the mushrooms, looked for add... more

When someone eats a mushroom and starts to feel sick, the first instinct is often to figure out exactly what mushroom it was. But mushroom identification is harder, riskier, and more specialized than most people realize.

In this bonus episode of A M... more

The Bozeman outbreak was the first loud signal, but it was not the only one.

After the CDC report, toxicologists in other countries started looking back through their own poison center data and found something unsettling: more patients with severe i... more

Hey everyone, it’s Ryan.

I know many of you are patiently waiting for Episode 6 of A Morel Dilemma, and it is coming next week. I genuinely cannot wait for you to hear this one.

But it is actually available right now for supporter members. You can ... more

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Recent Guests

Dr. Cripps
Mycology expert
Denver Poison Center / Scudder Diagnostic Lab
Episode: A Morel Dilemma- Bonus: Emergency Mushroom Identificaiton
Brooke Reed
Chief Operating Officer
NAMA
Episode: A Morel Dilemma- Bonus: Emergency Mushroom Identificaiton
Dominique Vodovar
Toxicologist, Paris Poison Center and Intensive Care Medicine expert
Paris Poison Center / University affiliations mentioned
Episode: A Morel Dilemma: Episode 6 — The Signal
Kathy Cripps
Mycologist, Montana State University; Professor Emerita
Montana State University
Episode: A Morel Dilemma: Episode 6 — The Signal
Ashutosh Tripathi
Founding director of Natural Product Discovery Core; toxin identification expert
University of Michigan
Episode: A Morel Dilemma: Episode 6 — The Signal
Catherine Isoardi
Emergency physician and clinical toxicologist, medical director of the Queensland Poisons Information Center
PA Hospital / Queensland Poisons Information Center
Episode: A Morel Dilemma Preview: Supporting Member Bonus Episodes
Darren Roberts
Nephrotoxicologist, medical director of the New South Wales Poisons and Information Center
New South Wales Poison Center
Episode: A Morel Dilemma Preview: Supporting Member Bonus Episodes
Amanda Hullford
Clinical toxicologist and emergency physician, PA hospital
PA Hospital
Episode: A Morel Dilemma Preview: Supporting Member Bonus Episodes
Grant Comstock
Emergency Medicine Physician, Medical Toxicologist
Medical College of Wisconsin; Wisconsin Poison Center
Episode: A Morel Dilemma: Episode 5 — Trial of the Morel

Host

Ryan Feldman
Host and clinical toxicologist with extensive experience in poison centers and emergency medicine.

Reviews

4.9 out of 5 stars from 228 ratings
  • Please shorten the intro

    It’s almost a full minute.

    Apple Podcasts
    4
    HeliNinja+
    United Statesa month ago
  • yay!

    Ilove this! i stumbled across a mention of it on IG and had to track it down. I have not been disappointed. It scratches so many good itches: mycology, true crime, mystery, poison, and poignant stories. I’m binging my way through.

    PS never eat sushi in a land-locked state.

    Apple Podcasts
    5
    psychopompous
    United Statesa month ago
  • Fantastic

    This is a fantastic podcast. There’s nothing as interesting as listening to smart people explaining the work they do and clearly love. In this age of discrediting science, this shows how important research and science is to every day life. Also I don’t think I will ever order a dish with mushrooms in a restaurant again!

    Apple Podcasts
    5
    Seamussf
    United Statesa month ago
  • Yes yes yes!

    This podcast addresses important topics in a way that a wide listener base can understand. I’m an inactive EMT, so optimistically, I thought I might be able to understand some of the content.

    It turns out that Dr Feldman understands his audience very well: it’s not hard at all to follow along because explanations are provided during the episode.

    The subject mix is unusual — it covers everything from identifying effects from designer street drugs to risks with using “natural” supplements to pot... more

    Apple Podcasts
    5
    O-possum
    United States2 months ago
  • Prior knowledge of toxicology not required!

    I may be outside the mainstream of the audience for this show as I have zero scientific or medical training. But I am curious about toxicology and pharmacology, and appreciate that the show makes that science accessible. The storytelling is always fascinating and entertaining, and I learn a lot.

    Apple Podcasts
    5
    AV718
    United States3 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The host and guests are described as knowledgeable and entertaining, with high production quality.
Listeners praise the accessible, engaging delivery of complex toxicology topics.
Many reviews note usefulness for exam preparation and professional learning.
Guests deliver practical clinical insights and real-world case discussions.
Show is a strong resource for high-risk, low-frequency emergencies and toxicology updates.

Talking Points

Recent interactions between the hosts and their guests.

A Morel Dilemma: Episode 6 — The Signal
Q: Why is identifying the toxin so challenging, and what strategies could help?
Mushrooms contain thousands of compounds; toxins can be present in very small, unstable quantities, and there is no single known toxin consistent across cases. The team is pursuing untargeted discovery by extracting all compounds, testing batches in cell systems, and leveraging proteomics and genomics to guide the chemistry.
A Morel Dilemma: Episode 6 — The Signal
Q: What initially prompted your study on morel poisoning and its severity?
The trigger came from a CDC Morbidity and Mortality Weekly Report that described a cluster of severe Cases linked to Morel exposure; that signal suggested a broader pattern and motivated cross-border collaboration to reexamine data from poison centers and hospitals.
A Morel Dilemma Preview: Supporting Member Bonus Episodes
Q: How did the Canadian outbreak signal differ from typical poisoning cases you handle?
Clinicians emphasized a rapid, clustered presentation after a shared meal, with many patients showing life-threatening arrhythmias and significant acidosis, which triggered immediate disaster-level coordination and public health involvement.
If I had a Nickel (Mystery Case) & Toxicologist vs The internet (#13) with Dr. Damilola Idowu-Ellsworth
Q: Why do I get muscle spasms in my hands after taking a lot of Lyrica?
Lyrica and similar drugs can disrupt the inhibitory and excitatory balance in motor control circuits, potentially leading to muscle spasms or myoclonus, especially when combined with other medications like baclofen.
If I had a Nickel (Mystery Case) & Toxicologist vs The internet (#13) with Dr. Damilola Idowu-Ellsworth
Q: What are the potential implications of GLP-1 medications on the release of toxins stored in adipose tissue?
There may be implications for chronic THC users, as rapid weight loss from GLP-1 medications could mobilize THC stored in fat, potentially leading to elevated serum levels. This could complicate drug test interpretations and bring legal concerns.

Audience Metrics

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Frequently Asked Questions About The Poison Lab

What is The Poison Lab about and what kind of topics does it cover?

The show targets professionals and students in toxicology, emergency medicine, and public health, often featuring clinical toxicologists and emergency physicians who discuss real-world poisonings, outbreaks, and case management. Episodes blend clinical insights with investigative storytelling, public health perspectives, and practical guidance for clinicians. A notable strength is the consistent focus on high-stakes, real-world toxicity scenarios, guest expertise from major poison centers and medical centers, and accessible explanations that educate both practitioners and curious listeners. It's particularly useful for those seeking case-driven learning, current toxicology topics, and practical takeaways for acute care and public health res... more

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Which podcasts are similar to The Poison Lab?

These podcasts share a similar audience with The Poison Lab:

1. EMS 20/20
2. The World’s Okayest Medic Podcast
3. The FlightBridgeED Podcast
4. EMCrit FOAM Feed
5. Sawbones: A Marital Tour of Misguided Medicine

How many episodes of The Poison Lab are there?

The Poison Lab launched 6 years ago and published 94 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Poison Lab?

Recent guests on The Poison Lab include:

1. Dr. Cripps
2. Brooke Reed
3. Dominique Vodovar
4. Kathy Cripps
5. Ashutosh Tripathi
6. Catherine Isoardi
7. Darren Roberts
8. Amanda Hullford

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