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The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus

BZ Group
Lilly
Merck & Co.
Gilead Sciences
FDA
Novo Nordisk
Bristol Myers Squibb
Regeneron
Eli Lilly
Sun Pharmaceutical Industries
Organon
Apogee Therapeutics
J&J Icotyde
Agentic AI
Foundayo
Neurocrine Biosciences
Pfizer
Glp-1
Novartis
United Therapeutics
Gilead

Your daily pharmaceutical news briefing — FDA decisions, clinical trial results, biotech M&A, and drug pipeline updates in under 15 minutes, every weekday. Hosted by Alex Mercer and Maya Patel. Plus a Weekend Edition every Sunday synthesizing the week's biggest moves in pharma and biotech. Covering drug approvals, pharma industry deals, biopharma investing, and healthcare market intelligence. Smar... more

PublishesDailyEpisodes71Founded3 months ago
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Artwork for The Pharma Closeout

Latest Episodes

Part 2 of The Pharma Closeout's ASCO 2026 special covers the closing days, Monday

June 1 and Tuesday June 2 — net-new readouts plus resolution of Part 1's June 1-2 watch-list. HEADLINE: izalontamab brengitecan (iza-bren), an EGFR-directed bis... more

ASCO 2026 comprehensive opening-weekend recap (28 readouts through Sunday, May 31). Headline: Revolution Medicines' RASolute 302 doubles overall survival in second-line pancreatic cancer (daraxonrasib, 13.2 vs 6.7months, HR 0.40). LUNG: CROWN 7-year ... more

RevMed's ASCO pancreatic cancer data earn 'unprecedented' from three major outlets — potential paradigm shift in a historically intractable tumor. Plus ivonescimab's 34% OS improvement with caveats,Pfizer-Innovent's $10.5B deal for 12 cancer programs... more

Pfizer and Innovent strike a deal worth up to $10.5B for 12 cancer programs — the sixth mega-licensing deal out of China since last July. BMS wins Phase 3 for Pomalyst successor mezigdomide at ASCO 2026. Merck, Agios, MannKind, and PDUFA reauthorizat... more

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Recent Guests

Marcus Webb
Investor/Market Analyst invited for commentary on deal dynamics
Episode: Mar 06, 2026 | FDA not convinced AMT-130 works; Moderna +14% on melanoma data; Servier’s $2.5B Day One bet

Hosts

Alex Mercer
Host of The Pharma Closeout; primary anchor across editions; frequently presents market and deal analysis.
Maya Patel
Co-host across editions; provides strategic and market-context commentary.

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Talking Points

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Mar 31, 2026 | Lilly's $7.8B Centessa Deal; Biogen Buys Apellis for $5.6B; FDA Flags Tavneos Deaths | Mar 31, 2026
Q: What does the CVR signal tell you about Lilly's deal structure?
It signals that Lilly is pricing in clinical uncertainty and tying part of the economics to milestones, effectively sharing downside risk with the seller while keeping upside tied to future performance.

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Frequently Asked Questions About The Pharma Closeout

What is The Pharma Closeout about and what kind of topics does it cover?

This briefing delivers fast, executive-focused coverage of pharma and biotech news, with a strong emphasis on drug approvals, clinical readouts, and M&A activity. Across episodes, listeners see concise synthesis of regulatory moves, deal dynamics, and pipeline updates, translated into practical implications for strategy, pitching, and investor positioning. Notable is the cadence: weekday fast briefs plus a Sunday wrap that ties together the week's biggest moves, helping professionals stay informed without sifting through lengthy reports. The format tends to feature real-time interpretation from two steady hosts, focusing on how data, policy, and market moves interact to shape competition, launches, and lifecycle decisions in cardiology, onc... more

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Which podcasts are similar to The Pharma Closeout?

These podcasts share a similar audience with The Pharma Closeout:

1. The Readout Loud
2. Pharmaceutical Executive
3. Global News Podcast
4. The Daily

How many episodes of The Pharma Closeout are there?

The Pharma Closeout launched 3 months ago and published 71 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Pharma Closeout?

Recent guests on The Pharma Closeout include:

1. Marcus Webb

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