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The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus

BZ Group
Lilly
Novo Nordisk
Gilead Sciences
Merck & Co.
Bristol Myers Squibb
FDA
GSK
Artificial Intelligence In Pharma
Pfizer
Glp-1
Regeneron
Eli Lilly
Sun Pharmaceutical Industries
Organon
J&J Icotyde
Apogee Therapeutics
Agentic AI
Foundayo
Revolution Medicines
Artificial Intelligence

Your daily pharmaceutical news briefing — FDA decisions, clinical trial results, biotech M&A, and drug pipeline updates in under 15 minutes, every weekday. Hosted by Alex Mercer and Maya Patel. Plus a Weekend Edition every Sunday synthesizing the week's biggest moves in pharma and biotech. Covering drug approvals, pharma industry deals, biopharma investing, and healthcare market intelligence. Smar... more

PublishesDailyEpisodes85Founded3 months ago
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ScienceLife Sciences

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Artwork for The Pharma Closeout

Latest Episodes

AbbVie bets $10.9B on Apogee Therapeutics to challenge Dupixent — its biggest deal since Allergan. Plus: the first CAR-T approved for a solid tumor clears in China, Merck's $10.8B Prometheus IBD bet pays off with a Phase 3 win, and HHS clinical trial... more

US government opens formal probe into Germany's drug pricing reforms, escalating transatlantic pharma trade tensions. Kardigan IPO raises $400M and pops 31%. Moderna flu vaccine gets unanimous FDA advisory panel support ahead of Aug 5 PDUFA. Jazz and... more

Moderna's mRNA flu vaccine gets unanimous FDA panel backing — PDUFA August 5. NovoCure's TRIDENT trial misses overall survival in glioblastoma; stock drops ~18%. Biogen acquires immunology startup RayThera for up to $1B; Kardigan IPO raises $400M.

V... more

UniQure surges 70% as FDA reverses course on Huntington's gene therapy AMT-130 filing path. Jazz and AbCellera strike $4.1B T cell engager deal for GI cancers. Novo Nordisk faces $25M ransom demand after hackers claim drug formulations and AI models.... more

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Recent Guests

Marcus Webb
Investor/Market Analyst invited for commentary on deal dynamics
Episode: Mar 06, 2026 | FDA not convinced AMT-130 works; Moderna +14% on melanoma data; Servier’s $2.5B Day One bet

Hosts

Alex Mercer
Host of The Pharma Closeout; primary anchor across editions; frequently presents market and deal analysis.
Maya Patel
Co-host across editions; provides strategic and market-context commentary.

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Talking Points

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Mar 31, 2026 | Lilly's $7.8B Centessa Deal; Biogen Buys Apellis for $5.6B; FDA Flags Tavneos Deaths | Mar 31, 2026
Q: What does the CVR signal tell you about Lilly's deal structure?
It signals that Lilly is pricing in clinical uncertainty and tying part of the economics to milestones, effectively sharing downside risk with the seller while keeping upside tied to future performance.

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Frequently Asked Questions About The Pharma Closeout

What is The Pharma Closeout about and what kind of topics does it cover?

This briefing delivers fast, executive-focused coverage of pharma and biotech news, with a strong emphasis on drug approvals, clinical readouts, and M&A activity. Across episodes, listeners see concise synthesis of regulatory moves, deal dynamics, and pipeline updates, translated into practical implications for strategy, pitching, and investor positioning. Notable is the cadence: weekday fast briefs plus a Sunday wrap that ties together the week's biggest moves, helping professionals stay informed without sifting through lengthy reports. The format tends to feature real-time interpretation from two steady hosts, focusing on how data, policy, and market moves interact to shape competition, launches, and lifecycle decisions in cardiology, onc... more

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Which podcasts are similar to The Pharma Closeout?

These podcasts share a similar audience with The Pharma Closeout:

1. Biotech Hangout
2. ASCO Daily News
3. The Readout Loud
4. BiotechTV - News
5. Pharma and BioTech Daily

How many episodes of The Pharma Closeout are there?

The Pharma Closeout launched 3 months ago and published 85 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Pharma Closeout?

Recent guests on The Pharma Closeout include:

1. Marcus Webb

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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