
Your daily pharmaceutical news briefing — FDA decisions, clinical trial results, biotech M&A, and drug pipeline updates in under 15 minutes, every weekday. Hosted by Alex Mercer and Maya Patel. Plus a Week in Review every Sunday synthesizing the week's biggest moves in pharma and biotech. Covering drug approvals, pharma industry deals, biopharma investing, and healthcare market intelligence. Smart... more
| Publishes | Daily | Episodes | 117 | Founded | 5 months ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Life SciencesScience | |||

AstraZeneca and Bristol Myers Squibb held months of merger talks valuing the combined company near $400 billion, per the Financial Times — a deal that would make AstraZeneca the world's fourth-largest drugmaker and draw antitrust scrutiny over two ov... more
Ziltivekimab missed its primary endpoint in the 6,300-patient Phase 3 ZEUS trial, sending Novo Nordisk down 10% and dragging BioAge Labs down 60% and Monte Rosa Therapeutics down 30%. Also: AbbVie's Skyrizi posts $5.5 billion in quarterly sales match... more
An FDA advisory panel backed Replimune's RP1 by 10 to 3, overriding agency reviewers, with an approval decision due August 2nd. Also: the same-day panel voted Capricor's Duchenne cell therapy deramiocel down 9 to 3, Johnson & Johnson took a $2.58 bil... more
FDA advisers recommended against Capricor's deramiocel — and the stock had already lost up to 60% before the vote. Also: Replimune falls nearly 40% as FDA reviewers call RP1's melanoma survival data uninterpretable ahead of Thursday's panel; Biogen p... more
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- A rapid-fire briefing on the pharma and biotech landscape, with a steady focus on regulatory decisions, FDA/EMA actions, pivotal trial readouts, and major deals. Across episodes, listeners get concise breakdowns of committee votes, data interpretability concerns, and how briefing documents shape market expectations and strategic decisions for developers, investors, and strategists. Notable threads include the regulatory risk around single pivotal readouts, the impact of M&A and deal re-structuring on portfolio strategy, and how market reactions, earnings, and guidance moves drive valuation and messaging in biotech and pharma.
- The show frequently ties regulatory and clinical momentum to near-term business implications, such as launch tim... more
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The Pharma Closeout launched 5 months ago and published 117 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on The Pharma Closeout include:
1. Nana Loonborg
2. Marcus Webb
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