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Artwork for The Open Loop

The Open Loop with Chay Carter

Chay Carter
Neurotechnology
Transcranial Magnetic Stimulation
Brain-Computer Interfaces
TMS
Stroke
EEG
Spark Biomedical
Post-Traumatic Stress Disorder
Depression
Nextsense
TDCS (transcranial Direct Current Stimulation)
Osmind
Omniscient
Conectomics
Neuroscience
Neuromodulation
Technology
Artificial Intelligence
Healthcare
Ketamine Esketamine

Neurotechnology is moving fast, but the real story is how it gets built, tested, funded, and scaled.

On The Open Loop, we explore the people, companies, and ideas shaping the future of neurotechnology, with honest conversations on what’s being built, what’s working, what’s difficult, and where the industry is really heading next.

Hosted by Chay Carter, Founder of Carter Sciences and Reccy Neur... more

PublishesWeeklyEpisodes23Founded6 months ago
Number of ListenersCategories
TechnologyScience

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Artwork for The Open Loop

Latest Episodes

In this episode of The Open Loop, Chay Carter is joined by Sudhin Shah and Jeremy Hill, Co-Founders of Cognitive Signals.

Sudhin is an Associate Professor of Neuroscience in Radiology at Weill Cornell Medicine, where her research focuses on cognitiv... more

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In this episode of The Open Loop, Chay Carter is joined by Mikko Karvinen, CEO of Nexstim, a Finnish neurotechnology company developing navigated transcranial magnetic stimulation (nTMS).

Mikko shares his journey from CFO to CEO during a challenging... more

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In this episode of The Open Loop, Chay Carter is joined by Mark Slater, Co-Founder of Otherside.

Mark shares how his personal experience living with epilepsy, combined with a career in healthcare advertising and brand strategy, led him to build Othe... more

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In this episode of The Open Loop, Chay Carter is joined by Ryan Glatt and Lauren Sergio of NERON.

Ryan is a Brain Health Coach and Director of the FitBrain℠ Program at Pacific Neuroscience Institute, where his work focuses on brain health, exercise ... more

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In this episode of The Open Loop, Chay Carter is joined by Adam Fraser, Chief Operating Officer at Omniscient Neurotechnology.

Adam shares how Omniscient is taking connectomics out of the lab and into clinical practice, using AI and MRI data to help... more

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In this episode of The Open Loop, Chay Carter is joined by Jonathan “JB” Berent, Founder and CEO of NextSense.

JB shares the story behind NextSense, from his early fascination with sleep and lucid dreaming to a Google X project exploring deep sleep ... more

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In this episode of The Open Loop, Chay Carter is joined by William Sauvé, MD, Chief Medical Officer at Osmind.

William shares his journey from Navy psychiatry and combat mental health care to TMS, interventional psychiatry, Greenbrook, and his curre... more

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In this episode of The Open Loop, Chay Carter is joined by Balder Onarheim, Founder and CEO of PlatoScience.

Balder shares his journey from the Norwegian army and engineering design into creativity research, brain stimulation, and building at-home t... more

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Key Facts

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Recent Guests

Mikko Karvinen
CEO of Nexstim, a Finnish neurotechnology company developing navigated transcranial magnetic stimulation
Nexstim
Episode: Navigated TMS and Precision Brain Stimulation with Mikko Karvinen
Mark Slater
Founder of Otherside (Otherside Health and Otherside Lounge)
Otherside
Episode: Why Neurotech Needs Lived Experience with Mark Slater
Lauren Sergio
Movement control neuroscientist at York University
York University, Toronto
Episode: Thinking, Moving and Measuring Brain Health with NERON
Adam Fraser
Chief Operating Officer at Omniscient
Omniscient
Episode: Connectomics and the Future of Brain Mapping with Adam Fraser
Jonathan Berent
CEO and founder of NextSense
NextSense
Episode: From Google X to NextSense: Building Brain-Sensing Smartbuds with Jonathan “JB” Berent
William Sauvé
Chief Medical Officer of Osmind
Osmind
Episode: Scaling Interventional Psychiatry with William Sauvé
Balder Onarheim
Founder of PlatoScience
PlatoScience
Episode: At-Home Brain Stimulation for Depression with Balder Onarheim
Ken Nelson
Executive with deep background in cardiac rhythm management, remote monitoring, and startup scaling
Nelson Jennings Ventures; Star 51 Capital; Mayo Clinic and Abbott anchor investors
Episode: What Neurotech Can Learn from Cardiac Digital Health with Ken Nelson
Corey Keller
Assistant Professor at Sanford; co-founder at Alto Neuroscience
Sanford; Alto Neuroscience
Episode: TMS, Neuroplasticity and Precision Psychiatry with Corey Keller, MD, PhD

Host

Chay Carter
Host of The Open Loop

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Talking Points

Recent interactions between the hosts and their guests.

Navigated TMS and Precision Brain Stimulation with Mikko Karvinen
Q: What does 2027 and beyond look like for Nexstim?
Karvinen points to the launch of the NBS6, growing orders through the Brainlab partnership, and the potential of the Sinaptica Therapeutics collaboration. He says Nexstim has become more financially stable and expects improved sales and profitability in 2026.
Navigated TMS and Precision Brain Stimulation with Mikko Karvinen
Q: What was the journey of you guys focusing on Stroke first, and then what's the pivots being sent?
Nexstim's phase three stroke rehabilitation trial produced results similar to the earlier study, but the sham control group had a similar effect. The company refocused on established areas, including presurgical brain mapping and depression treatment.
At-Home Brain Stimulation for Depression with Balder Onarheim
Q: What separates PlatoScience from other TDCS players in the market?
Balder explains that the core distinction lies in the hardware design and clinician-led model: highly usable, portable devices with thoughtful ergonomics and reliability, paired with a strategy to provide devices through clinicians rather than direct-to-consumer sales, which helps preserve treatment integrity and safety.
Scaling Interventional Psychiatry with William Sauvé
Q: How does Osmind position itself in a maturing field with data and real-world outcomes?
Sauvé highlights Osmind's focus on building an EHR tailored for mental health interventional workflows, enabling REMS integration, capturing ketamine/TMS outcomes, and accumulating real-world data from thousands of clinics to demonstrate effectiveness and inform reimbursement and policy decisions.
Scaling Interventional Psychiatry with William Sauvé
Q: How did you end up founding Virginia Interventional Psychiatry and what were the challenges with TMS adoption in hospitals?
He explains that hospital leadership historically weren't willing to invest in TMS due to concerns over insurance coverage and polypharmacy, but a CEO ultimately supported introducing TMS in a military-leaning program. This led to growth and a dedicated center in Richmond, later expanding to Charlottesville and Virginia Beach before rebranding as Greenbrook.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
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Frequently Asked Questions About The Open Loop

What is The Open Loop about and what kind of topics does it cover?

The show centers on the people, companies, and ideas driving neurotechnology, with candid conversations about building and scaling technology at the intersection of neuroscience and healthcare. Episodes typically feature founders, researchers, operators, investors, and industry leaders discussing topics like brain-computer interfaces, neuromodulation, neuro-AI, regulatory realities, clinical pathways, and the commercial challenges of bringing breakthrough devices to market. Noteworthy angles include founder journeys, cross-domain collaboration, data strategy and privacy considerations, and the evolving investment landscape that underpins hardware and software innovations. Listeners can expect practical, unfiltered insight into how neurotech... more

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The Open Loop launched 6 months ago and published 23 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Open Loop?

Recent guests on The Open Loop include:

1. Mikko Karvinen
2. Mark Slater
3. Lauren Sergio
4. Adam Fraser
5. Jonathan Berent
6. William Sauvé
7. Balder Onarheim
8. Ken Nelson

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