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Exosomes
Hyperbaric Oxygen Therapy
Heart Rate Variability
Stem Cells
Resonance Breathing
Vagus Nerve
Dna-Based Nutrigenomics
Video Marketing
Longevity
Brain Aging
Longevity Medicine
Natural Killer Cells
Silicon Valley
Ohm Health
SNP Nutrigenomics
OM Health
Longevity Clinics
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Scottsdale, United States
Bioedge Longevity Summit

Hey, I'm Brent Wallace, and it's exciting to share my podcast, The Longevity Loop, with folks who are interested in the topic of anti-aging and longevity science who, at the same time, are dedicated to growing their longevity-focused business, whether that be a brick and mortar clinic or an eCommerce endeavor. I'm 100% all in on helping people who run clinics and businesses that focus on helping f... more

PublishesWeeklyEpisodes21Foundeda year ago
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Health & FitnessAlternative HealthMedicine

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Artwork for The Longevity Loop Podcast

Latest Episodes

Living longer sounds like the ultimate win, until you ask the question most people skip: what are we doing with the extra time? I’m joined by filmmaker David Donnelly, creator of Forever Young, to talk about the very real longevity revolution now unf... more

Pain can be a warning, but it can also be proof your body is still fighting to repair. I bring on Dr. Park to unpack chronic pain as a neurological phenomenon, why inflammation is sometimes part of healing, and how people get trapped chasing symptom ... more

You can crush workouts, hit great HRV numbers, and still have arteries aging faster than you are. That’s the uncomfortable gap we dig into with Dr. Craig Backs, a 40+ year physician who calls himself a “recovering allopath” and now focuses on proacti... more

A $27,000 hyperbaric chamber should have been a shortcut to better brain health. Instead, it triggered massive headaches and exposed a hard truth about longevity and biohacking: the “best” optimization tools can fail when you haven’t removed what’s h... more

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Recent Guests

David Donnelly
Filmmaker, producer of the documentary Forever Young
Forever Young film
Episode: If We Add Years To Life What Adds Life To Years
Dr. Park
Longevity and regenerative medicine expert
Recharge Biomedical
Episode: How To Restart Healing When Pain Won’t Quit
Dr. Craig Backs
Physician, founder of Cure Center and Cure Coach
Cure Center; Cure Coach
Episode: What If Feeling Fit Is Not Enough
Sandy Martin
Creator of the Biological Edge Framework; Founder of the BioEdge Longevity Summit; Author of Biological Edge and BioHacking Starts with No
Biological Edge, BioEdge Longevity Summit
Episode: Biohacking Starts With No
Dr. Glorioso
Runs NeuroAge newsletter and brain aging research program
NeuroAge
Episode: How To Measure Brain Aging And Lower Dementia Risk Early
Dr. Jay Wiles
Performance psychologist and psycho-physiology expert focused on the nervous system
OM Health
Episode: What Heart Rate Variability Really Measures
Kim Ressler
Guest on the show; expert/entrepreneur in SNP Nutrigenomics
SNP Nutrigenomics
Episode: DNA-Based Nutrition That Actually Guides Your Choices
Alex Kratowski
Author and journalist focused on technology and society, author of The Immortalists
BBC (journalist background); author
Episode: Who Gets To Live Longer, And Who Decides?
Dr. Jeffrey Gross
Stem cell and regenerative medicine specialist, founder of Re-Celebrate
Re-Celebrate
Episode: One Shot To Skip The Scalpel

Host

Brent Wallace
Host of The Longevity Loop Podcast

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Talking Points

Recent interactions between the hosts and their guests.

If We Add Years To Life What Adds Life To Years
Q: What pulled you into longevity filmmaking in the first place?
The filmmaker describes encountering a flood of longevity content online, skepticism about hype, and then discovering real scientific progress at places like the Buck Institute, which framed longevity as a real, multi-faceted revolution rather than a hype cycle.
How To Measure Brain Aging And Lower Dementia Risk Early
Q: What are the potential downsides of lithium as discussed in this episode?
Lithium carbonate has strong firing-blocking effects and is not ideal for cognitive sharpness; evidence in longevity primarily concerns lithium orotate at much lower doses, and robust human trials are pending.
How To Measure Brain Aging And Lower Dementia Risk Early
Q: What does NeuroAge testing involve and what does the 'brain age' number mean?
NeuroAge combines brain MRI, cognitive testing, and 52 RNA blood biomarkers to estimate brain age; being younger than your chronological age by about five years corresponds to markedly lower risk of future Alzheimer's.
How To Measure Brain Aging And Lower Dementia Risk Early
Q: How does ApoE4 affect brain aging and what can people do if they have this allele?
ApoE4 is a major genetic risk factor that worsens brain aging by affecting cholesterol transport in the brain; however, lifestyle interventions like diet, exercise, sleep, and managing vascular risk can significantly influence outcomes.
How To Measure Brain Aging And Lower Dementia Risk Early
Q: What pulled you into brain aging and what makes it personal for you?
Dr. Glorioso discusses her family history with Alzheimer's, which drives both her scientific focus and her commitment to preventive brain health through comprehensive testing and lifestyle strategies.

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Frequently Asked Questions About The Longevity Loop Podcast

What is The Longevity Loop Podcast about and what kind of topics does it cover?

A cutting-edge show focused on longevity science and building a profitable longevity-centered business. Across episodes, listeners hear practitioners, researchers, and entrepreneurs discuss practical ways to improve healthspan—from video marketing for clinics and nutrigenomics-driven nutrition to sleep optimization, HRV-based nervous-system training, and regenerative therapies. Guests are often founders, clinicians, or researchers who blend actionable health insights with real-world business strategies, including go-to-market tactics, patient acquisition, pricing, and scalable service delivery. The format tends to balance technical explanations with concrete steps for implementing the discussed ideas in clinics, wellness practices, or direc... more

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1. Huberman Lab

How many episodes of The Longevity Loop Podcast are there?

The Longevity Loop Podcast launched a year ago and published 21 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Longevity Loop Podcast?

Recent guests on The Longevity Loop Podcast include:

1. David Donnelly
2. Dr. Park
3. Dr. Craig Backs
4. Sandy Martin
5. Dr. Glorioso
6. Dr. Jay Wiles
7. Kim Ressler
8. Alex Kratowski

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