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Artwork for The Lancet Infectious Diseases in conversation with

The Lancet Infectious Diseases in conversation with

The Lancet Group
Clinical Trials
Artificial Intelligence
Public Health
Covid-19
Antimicrobial Resistance
Infectious Diseases
Long Covid
Sars-Cov-2
Pediatric Infectious Disease
Oropuche Virus
Research Funding
Mental Health
Diagnostic Systems
Treatment Strategies
Tuberculosis
Pathogen Characterization
Adaptive Platform Trials
Dengue
Zika Virus
Chikungunya Virus

Saleha Hassan, Senior Editor at The Lancet Infectious Diseases, in conversation with the journal’s authors, explores their latest research and its impact on people’s health, healthcare, and health policy.

A monthly audio companion to the journal, this podcast covers a broad range of topics, from polio eradication in Africa to COVID-19 vaccines in Hong Kong, the treatment of early syphilis in adult... more

PublishesInfrequentlyEpisodes121Founded5 years ago
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MedicineHealth & FitnessScienceLife Sciences

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Artwork for The Lancet Infectious Diseases in conversation with

Latest Episodes

Dr Jenny Clarke and Herve Semukunzi discuss a study they and colleagues recently published with us  titled ‘Infection- and vaccine-induced mpox antibodies: validation of a combined mpox IgG ELISA during the clade 1b outbreak in Rwanda’. 

They also d... more

Dr Julia Moore Vogel and Dr Danilo Buonsenso discuss various aspects of long COVID including epidemiology, pathophysiology, underlying mechanisms, management, latest research developments, difficulties in conducting clinical trials, and future resear... more

Professors Steven Tong and Joshua Davis discuss all aspects of adaptive platform trials including advantages, disadvantages, differences from conventional trials, and tips for setting up and assessing them.

They also highlight several adaptive platf... more

Professor Ana Odone, Dr Jesus Rodriguez-Manzano, and Dr Alex Howard discuss their new Series of papers on artificial intelligence and infectious diseases intended to support the infectious diseases community in understanding this evolving landscape a... more

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Recent Guests

Dr. Julia Moore Vogel
Assistant Professor and Senior Programme Director at Scripps Research Translational Research Institute
Scripps Research Translational Research Institute
Episode: Julia Moore Vogel and Danilo Buonsenso on long COVID
Steven Tong
Infectious Diseases Physician at the Victorian Infectious Diseases Service, Royal Melbourne Hospital
Doherty Institute, University of Melbourne
Episode: In Conversation with Steven Tong and Joshua Davis on adaptive platform trials
Joshua Davis
Infectious Diseases Physician and Clinical Trialist, School of Medicine and Public Health
University of Newcastle, Australia
Episode: In Conversation with Steven Tong and Joshua Davis on adaptive platform trials
Jan Felix Drexler
Professor from Charité Universität Medizin in Berlin, Germany
Charité Universität Medizin
Episode: Jan Felix Drexler and Fernando Bozza on Oropouche virus
Fernando Bozza
Professor from the National Institute of Infectious Diseases, Evandro Chagas, Osvaldo Cruz Foundation, Brazil
National Institute of Infectious Diseases
Episode: Jan Felix Drexler and Fernando Bozza on Oropouche virus

Host

Saleha Hassan
Senior Editor for The Lancet Infectious Diseases (and related Lancet journals) involved in conversations with authors about research impact on health policy and practice.

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Talking Points

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Julia Moore Vogel and Danilo Buonsenso on long COVID
Q: What should be the future research, clinical, and funding priorities for long COVID?
There is an urgent need for increased funding, especially for trials including children and adolescents, and for continued focus on biomarkers and clinical support initiatives.
Julia Moore Vogel and Danilo Buonsenso on long COVID
Q: What is known about the pathophysiology of long COVID?
The pathophysiology is complex; it involves ongoing immune dysfunction, potential persistence of the virus in tissues, and chronic inflammatory responses which often remain neglected.
Julia Moore Vogel and Danilo Buonsenso on long COVID
Q: Long Covid has various definitions. Can you tell us a bit more on why this is and what are the definitions that have been widely used by the clinical research community?
The definitions are diverse due to the wide array of symptoms and experiences post-COVID-19; the current standard follows a broad approach by the National Academies due to the lack of specific markers.
Julia Moore Vogel and Danilo Buonsenso on long COVID
Q: How common is long Covid, and does prevalence incidence differ between children and adults? Are there groups who are disproportionately affected?
Long Covid affects about 4% of children and 10-25% of adults, with female gender and a history of allergies marking higher risk. Both younger children and adolescents show disproportional effects.
In Conversation with Steven Tong and Joshua Davis on adaptive platform trials
Q: Can you highlight the advantages and disadvantages of adaptive platform trials compared with conventional trials?
The advantages include efficiencies in time and costs by addressing multiple questions at once. The disadvantages involve increased complexity and longer startup times.

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This show features conversations with leading researchers, clinicians, and policy experts focusing on infectious diseases, clinical trials, and health systems. Episodes commonly explore new evidence on emerging pathogens, diagnostics, vaccination strategies, and treatment approaches, often linking research findings to real-world healthcare impacts and policy considerations. A notable strength is the ability to translate complex trial designs, epidemiology, and public health implications into accessible discussions, frequently highlighting unmet needs, funding, and collaboration across institutions and countries. The format tends to pair scientists with others in the field to unpack cutting-edge topics—ranging from long COVID and adaptive pl... more

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1. NEJM This Week
2. Febrile
3. JAMA Medical News
4. JAMA Editors' Summary
5. JAMA Clinical Reviews

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this podcast launched 5 years ago and published 121 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Recent guests on this podcast include:

1. Dr. Julia Moore Vogel
2. Steven Tong
3. Joshua Davis
4. Jan Felix Drexler
5. Fernando Bozza

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