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Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up, Cell Culture Innovation

David Brühlmann - CMC Development Leader, Biotech C-level Advisor, Business Strategist
Biotechnology
Stakeholder Management
Impedance Flow Cytometry
Bioprocess Development
Bioprocessing
Biologics
CMC Development
Bead-Based Assays
Biologics Manufacturing
Biopharmaceuticals
Artificial Intelligence
Cell Factories
Synthetic Biology
Regulatory Compliance
Cultivated Meat
High Throughput Screening
Single-Cell Analysis
Cell and Gene Therapies
Quality Control
Cell Culture

The Go-to Podcast for Biotech Scientists Who Want to Master Biopharma CMC Development and Biomanufacturing.

**TOP 10 LIFE SCIENCES PODCAST**

Are you ready to simplify bioprocess development and scale with confidence to reduce time to market?

Are you feeling overwhelmed by the complexity and guesswork of biologics development and biomanufacturing?

Do you wish you had more time to enjoy the beauty o... more

PublishesTwice weeklyEpisodes212Founded2 years ago
Number of ListenersCategories
Life SciencesScience

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Artwork for Smart Biotech Scientist

Latest Episodes

Real progress in cell and gene therapy shouldn’t be measured solely by scientific innovation, but by whether those innovations actually reach the patients who need them most.

In this episode, David Brühlmann sits down with Jesús Zurdo, a scientist w... more

From pandemic-speed vaccine deployment to AI-powered process control, what separates hype from real manufacturing transformation?

The biotech industry faces a fundamental challenge: how do you maintain rigorous quality standards while accelerating d... more

The biotech industry operates under constant tension: we work with products that directly impact human lives, demanding rigorous controls and validation at every step. Yet standing still means falling behind. The question isn't whether to innovate, i... more

What if you could analyze every metabolite, glycan variant, and unknown impurity in your bioprocess sample—not just the targets you're looking for, but everything that's actually there? Cryogenic infrared ion spectroscopy combined (CIRIS) with AI-pow... more

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Recent Guests

Tom Rizzo
Former Dean of the School of Basic Sciences at EPFL, Chief Scientific Officer at Isospec Analytics
Isospec Analytics
Episode: 207: Cryogenic Infrared Ion Spectroscopy: From Mass Spec Limitations to Molecular Precision with Tom Rizzo - Part 1
Niklas Jungnelius
Process modeling expert at Cytiva
Cytiva
Episode: 206: Process Economics Decoded: How to Model Biomanufacturing Costs From Clinical to Commercial Scale with Niklas Jungnelius - Part 2
Daniel Galbraith
Chief Scientific Officer at Solvias with nearly three decades of experience guiding analytical development
Solvias
Episode: 203: Mastering CRO Selection: Essential Questions for CMC Analytical Development with Daniel Galbraith - Part 1
Amanda Hoertz
Expert in ADC development and project management
KBI Biopharma
Episode: 198: Mastering ADC Development: CDMO Strategies for Analytics and Scale-Up with Amanda Hoertz - Part 2
Alois Jungbauer
Professor emeritus of downstream processing at the Institute of Bioprocessed Science at Technology at BOKU University in Vienna
BioChromatographix International
Episode: 196: Monolithic Chromatography Innovations: Solving High-Capacity Purification for Gene Therapy Vectors with Alois Jungbauer - Part 2
Lucas Chan
A molecular and cell biologist with over 20 years in cell and gene therapy development.
CellVec, APAC's first GMP certified specialist CDMO for viral vectors
Episode: 193: Viral Vector CDMO Mastery: Singapore's Answer to Cell and Gene Therapy Supply Shortages with Lucas Chan - Part 1
Andreas Castan
A 25-year industry veteran who provides leadership and support to Cytiva's bioprocess business.
Cytiva
Episode: 191: Process Intensification Secrets: A Process Engineer's Decision Framework with Andreas Castan - Part 1
Carmen Jungo Rhême
Professor at the University of Applied Sciences and Director of the Biofactory Competence Center
University of Applied Sciences, Freiburg, Switzerland
Episode: 187: From Biology Is Messy to Designable: The Smart Bioprocessing Transformation with Carmen Jungo Rhême - Part 1
Elise de Reus
AI and protein design expert at Cradle
Cradle
Episode: 186: How Generative AI Accelerates Protein Design for Biotech Discovery with Elise de Reus - Part 2

Host

David Brühlmann
Host with extensive experience in biopharma CMC development and biomanufacturing, known for engaging conversations with industry experts.

Reviews

4.9 out of 5 stars from 29 ratings
  • Good stuff !

    I am enjoying this podcast and always learn a thing or two! Thanks David!

    Apple Podcasts
    5
    Rob78_13
    United Statesa year ago
  • Insightful!

    I love my weekly dose of the Smart Biotech Scientist podcast! I enjoy hearing and learning from my peers in the biopharmaceutical development field, gaining new insights and perspectives on CMC development challenges, tech, and strategies. The host is knowledgeable and engaging, bringing expert guests who share their cutting-edge strategies and real-world experiences. Whether you’re a seasoned professional or new to the field, this podcast offers practical advice and innovative solutions that c... more

    Apple Podcasts
    5
    Giulia Lambiase
    United Kingdoma year ago
  • Great interviews, good format

    David delivers a great podcasts: I like the depth of the conversations and also that the episodes have the perfect length for my commute to work👍

    Apple Podcasts
    5
    pilldipp
    Germany2 years ago
  • Deeply Refreshing Perspective

    I am really a fan of David’s content and his approach to intriguing subjects.

    Apple Podcasts
    5
    Stem Cell Guy
    United States2 years ago
  • Fantastic content!

    Great podcast! Highly recommend that anybody working in biotech listen to this podcast. David, the host, is very knowledgeable in the bio tech space. I have enjoyed the insights from the guests.

    Apple Podcasts
    5
    MatthiasV1976
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The host is praised for his engaging style and ability to simplify complex topics, making them accessible to a wider audience.
Listeners find the content insightful and informative, often mentioning the depth of discussions and actionable insights.
Many appreciate the high-quality guests and relevant industry topics, showcasing the podcast's value in the biotech community.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

208: Cryogenic Infrared Ion Spectroscopy: From Mass Spec Limitations to Molecular Precision with Tom Rizzo - Part 2
Q: What advice would you give a scientist, a PhD or postdoc who would now like to start his or her company?
It's important to be passionate about your work, as R&D in a startup can be challenging and there's a lot to learn.
208: Cryogenic Infrared Ion Spectroscopy: From Mass Spec Limitations to Molecular Precision with Tom Rizzo - Part 2
Q: What is your vision of the technology?
We see it going in a couple of different directions, providing a service platform for analyzing biological samples and equipping researchers with tools for disease mechanism analysis.
205: Process Economics Decoded: How to Model Biomanufacturing Costs From Clinical to Commercial Scale with Niklas Jungnelius - Part 1
Q: For those listening who might be new to process modeling, can you just tell us what process modeling actually looks like?
Process economic modeling looks at cost of manufacturing, capacity models, and incorporates variables that impact process efficiency and the total cost of manufacturing.
205: Process Economics Decoded: How to Model Biomanufacturing Costs From Clinical to Commercial Scale with Niklas Jungnelius - Part 1
Q: Niklas, share something that you believe about bioprocess development that most people disagree with.
I personally do not think that fully continuous bioprocessing will become the dominant manufacturing mode for new mammalian processes within the coming 15 years.
204: Mastering CRO Selection: Essential Questions for CMC Analytical Development with Daniel Galbraith - Part 2
Q: What is the most important takeaway from our conversation?
The importance of understanding and developing a partnership with CROs for successful project outcomes.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Smart Biotech Scientist

What is Smart Biotech Scientist about and what kind of topics does it cover?

This podcast serves as a valuable resource for biotech professionals, particularly those involved in biopharma CMC (Chemistry, Manufacturing, and Controls) development and biomanufacturing. Engaging conversations with industry experts provide practical insights into overcoming challenges within bioprocess development and scaling up the manufacturing of biologics. Topics such as strategizing for faster market delivery, optimizing manufacturing costs, and utilizing innovative techniques in cell culture and gene therapies are frequently explored, making the content highly relevant and actionable for listeners in the biotechnology space. The host combines expert perspectives with real-world experiences, encouraging aspiring biochemists and inno... more

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Which podcasts are similar to Smart Biotech Scientist?

These podcasts share a similar audience with Smart Biotech Scientist:

1. The Diary Of A CEO with Steven Bartlett
2. BioCentury This Week
3. TED Talks Daily
4. ADHD Chatter
5. The Intelligence from The Economist

How many episodes of Smart Biotech Scientist are there?

Smart Biotech Scientist launched 2 years ago and published 212 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Smart Biotech Scientist?

Recent guests on Smart Biotech Scientist include:

1. Tom Rizzo
2. Niklas Jungnelius
3. Daniel Galbraith
4. Amanda Hoertz
5. Alois Jungbauer
6. Lucas Chan
7. Andreas Castan
8. Carmen Jungo Rhême

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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