Smart Biotech Scientist | The CMC and Bioprocessing Podcast for Process Development and Manufacturing Leaders
David Brühlmann - CMC Development Leader, Bioprocess Expert, Business StrategistThe go-to CMC and biomanufacturing podcast for bioprocess development scientists and CMC leaders scaling biologics into regulatory-ready therapies with less trial and error.
Practical, execution-focused, and strategic guidance on CMC development, tech transfer, scale-up, GMP readiness, CDMO partnerships, and manufacturing economics for biologics, cell and gene therapies, cultivated meat, and biom... more
| Publishes | Daily | Episodes | 299 | Founded | 3 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Life SciencesScience | |||
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Latest Episodes
The entire public record of antibody affinity data comes to about half a million measurements, and by David Younger's estimate, upwards of 75% of it is AlphaSeq data from his own company's publications. His conclusion is that no single company can cl... more
The Protein Data Bank holds about 10,000 antibody-antigen structures and grows by roughly 1,000 a year. David Younger's scaling work suggests that generalizable de novo antibody design needs hundreds of thousands to millions. At that pace, even 200,0... more
Cardiovascular disease has long been managed by slowing its relentless progression. But Matthew O'Connor, CEO of Scientific Affairs at Cyclarity Therapeutics, is betting on an outright paradigm shift: treating atherosclerotic plaque with therapies de... more
Why does CMC development still expect every drug to be one molecule with one peak, when new therapeutics don't always fit neatly into existing regulatory or chemical categories?
Matthew O'Connor, CEO of Scientific Affairs at Cyclarity Therapeutics, ... more
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Reviews
- Good stuff !
I am enjoying this podcast and always learn a thing or two! Thanks David!
Apple Podcasts5Rob78_13
United States2 years ago - Insightful!
I love my weekly dose of the Smart Biotech Scientist podcast! I enjoy hearing and learning from my peers in the biopharmaceutical development field, gaining new insights and perspectives on CMC development challenges, tech, and strategies. The host is knowledgeable and engaging, bringing expert guests who share their cutting-edge strategies and real-world experiences. Whether you’re a seasoned professional or new to the field, this podcast offers practical advice and innovative solutions that c... more
Apple Podcasts5Giulia Lambiase
United Kingdom2 years ago - Great interviews, good format
David delivers a great podcasts: I like the depth of the conversations and also that the episodes have the perfect length for my commute to work👍
Apple Podcasts5pilldipp
Germany3 years ago - Deeply Refreshing Perspective
I am really a fan of David’s content and his approach to intriguing subjects.
Apple Podcasts5Stem Cell GuyUnited States3 years ago - Fantastic content!
Great podcast! Highly recommend that anybody working in biotech listen to this podcast. David, the host, is very knowledgeable in the bio tech space. I have enjoyed the insights from the guests.
Apple Podcasts5MatthiasV1976United States3 years ago
Listeners Say
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Chart Rankings
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #201 | United States/Science/Life Sciences |
Apple Podcasts | #125 | United Kingdom/Science/Life Sciences |
Apple Podcasts | #9 |  France/Science/Life Sciences |
Apple Podcasts | #67 |  Italy/Science/Life Sciences |
Apple Podcasts | #123 | Germany/Science/Life Sciences |
Apple Podcasts | #137 | France/Science |
Talking Points
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Audience Metrics
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Frequently Asked Questions About Smart Biotech Scientist
What is Smart Biotech Scientist about and what kind of topics does it cover?
A practical, execution-focused show that speaks to bioprocess development and CMC leaders scaling biologics and cell/gene therapies toward regulatory readiness. Episodes center on manufacturing scale-up, technology transfer, process development, data and automation in labs, and the economics of biopharma production, with frequent guests from major biotech suppliers, CDMOs, and innovative startups. Listeners are likely looking for actionable guidance on scale-up strategies, regulatory readiness, GMP/CMC planning, and how digital tools and AI can streamline development. A standout pattern is the access to practitioner-level insights from leaders driving real-world manufacturing improvements, often framed around building scalable platforms and... more
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How many listeners does Smart Biotech Scientist get?
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Which podcasts are similar to Smart Biotech Scientist?
These podcasts share a similar audience with Smart Biotech Scientist:
1. The Indicator from Planet Money
2. Planet Money
3. The Daily
4. Bioprocessing Unfiltered
5. The Intelligence from The Economist
How many episodes of Smart Biotech Scientist are there?
Smart Biotech Scientist launched 3 years ago and published 299 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
How do I contact Smart Biotech Scientist?
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What guests have appeared on Smart Biotech Scientist?
Recent guests on Smart Biotech Scientist include:
1. Matthew O'Connor
2. Christian Witz
3. John Bonham-Carter
4. Sandra Núñez
5. Sigma Mostafa
6. Nathan Lewis
7. Kent Rapp
8. Jitendra Kumar
To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.