
The go-to CMC and biomanufacturing podcast for bioprocess development scientists and CMC leaders scaling biologics into regulatory-ready therapies with less trial and error.
Practical, execution-focused, and strategic guidance on CMC development, tech transfer, scale-up, GMP readiness, CDMO partnerships, and manufacturing economics for biologics, cell and gene therapies, cultivated meat, and biom... more
| Publishes | Twice weekly | Episodes | 265 | Founded | 3 years ago |
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| Number of Listeners | Categories | ScienceLife Sciences | |||

Digital transformation in biotech is no longer just about adopting new tools, it's about building a foundation where automation, data standardization, and AI integration actually lead to real value and long-term success.
For today’s episode, David B... more
Despite cutting-edge equipment and brilliant minds, biotech labs often find half their data trapped in difficult-to-access spreadsheets or isolated in silos, making true digital transformation a major, industry-wide hurdle.
David Hardy, a leading ma... more
Host David Brühlmann returns for a focused solo episode to provide an honest, data-driven perspective on the evolving landscape of host selection for biologics manufacturing. Building on part one, David reviews five alternative expression platforms a... more
In this solo episode, David Brühlmann explores the evolving landscape of biologic manufacturing platforms beyond CHO (Chinese hamster ovary) cells. Drawing from previous interviews with platform pioneers and rigorous data analysis, David examines whe... more
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I am enjoying this podcast and always learn a thing or two! Thanks David!
I love my weekly dose of the Smart Biotech Scientist podcast! I enjoy hearing and learning from my peers in the biopharmaceutical development field, gaining new insights and perspectives on CMC development challenges, tech, and strategies. The host is knowledgeable and engaging, bringing expert guests who share their cutting-edge strategies and real-world experiences. Whether you’re a seasoned professional or new to the field, this podcast offers practical advice and innovative solutions that c... more
David delivers a great podcasts: I like the depth of the conversations and also that the episodes have the perfect length for my commute to work👍
I am really a fan of David’s content and his approach to intriguing subjects.
Great podcast! Highly recommend that anybody working in biotech listen to this podcast. David, the host, is very knowledgeable in the bio tech space. I have enjoyed the insights from the guests.
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #79 | |
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Apple Podcasts | #206 | |
Apple Podcasts | #36 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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The show targets process development scientists and CMC leaders driving biologics into regulatory-ready therapies, with a practical, execution-focused angle on scale-up, tech transfer, GMP readiness, CDMO partnerships, and manufacturing economics. Episodes feature deep dives into cell therapy, bioprocess optimization, analytics, and regulatory strategy, often weaving in real-world practicalities, vendor and partner perspectives, and forward-looking tech like continuous manufacturing and digital twins. A standout aspect is the guest mix: senior industry practitioners and established biotech leaders share actionable frameworks, from SHAKe-scale decisions to complex CMC programs, making it a valuable resource for both hands-on engineers and bi... more
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These podcasts share a similar audience with Smart Biotech Scientist:
1. BioCentury This Week
2. Science Magazine Podcast
3. Biotech Hangout
4. Christiane Amanpour Presents: The Ex Files
5. Dwarkesh Podcast
Smart Biotech Scientist launched 3 years ago and published 265 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on Smart Biotech Scientist include:
1. Milan Tomic
2. Steffen Kreye
3. Yuta Lee
4. Chantale Bernatchez
5. Ron Najafi
6. Tibor Anderlei
7. Steve Oh
8. Juergen Mairhofer
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