
The go-to CMC and biomanufacturing podcast for bioprocess development scientists and CMC leaders scaling biologics into regulatory-ready therapies with less trial and error.
Practical, execution-focused, and strategic guidance on CMC development, tech transfer, scale-up, GMP readiness, CDMO partnerships, and manufacturing economics for biologics, cell and gene therapies, cultivated meat, and biom... more
| Publishes | Twice weekly | Episodes | 277 | Founded | 3 years ago |
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| Number of Listeners | Categories | Life SciencesScience | |||

How do you turn a lab-born regenerative medical device into a solution that surgeons actually want to use and investors want to back? The path from academic innovation to clinical adoption is full of practical hurdles and strategic pivots, where comp... more
Imagine a wound too large for the body to close on its own. That's the problem Eva-Maria Balet set out to solve, not with living cells, but with a structural bridge that lets the body's own healing mechanisms do the rest.
In this episode, David Brüh... more
Building a cell therapy company is hard. Building a genetically engineered iPSC therapy for the brain, on a preclinical budget, is one of the hardest translational problems in biotech. Every experiment has to move the program closer to an IND, or it'... more
Transplant iPSC-derived neurons into a Parkinson's brain and 97% die before they can restore function. Of the 3% that survive, most face the same pathogenic environment that killed the original neurons. This is the compounded biology and CMC problem ... more
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I am enjoying this podcast and always learn a thing or two! Thanks David!
I love my weekly dose of the Smart Biotech Scientist podcast! I enjoy hearing and learning from my peers in the biopharmaceutical development field, gaining new insights and perspectives on CMC development challenges, tech, and strategies. The host is knowledgeable and engaging, bringing expert guests who share their cutting-edge strategies and real-world experiences. Whether you’re a seasoned professional or new to the field, this podcast offers practical advice and innovative solutions that c... more
David delivers a great podcasts: I like the depth of the conversations and also that the episodes have the perfect length for my commute to work👍
I am really a fan of David’s content and his approach to intriguing subjects.
Great podcast! Highly recommend that anybody working in biotech listen to this podcast. David, the host, is very knowledgeable in the bio tech space. I have enjoyed the insights from the guests.
Key themes from listener reviews, highlighting what works and what could be improved about the show.
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Listeners, social reach, demographics and more for this podcast.
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The show targets process development scientists and CMC leaders driving biologics into regulatory-ready therapies, with a practical, execution-focused angle on scale-up, tech transfer, GMP readiness, CDMO partnerships, and manufacturing economics. Episodes feature deep dives into cell therapy, bioprocess optimization, analytics, and regulatory strategy, often weaving in real-world practicalities, vendor and partner perspectives, and forward-looking tech like continuous manufacturing and digital twins. A standout aspect is the guest mix: senior industry practitioners and established biotech leaders share actionable frameworks, from SHAKe-scale decisions to complex CMC programs, making it a valuable resource for both hands-on engineers and bi... more
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These podcasts share a similar audience with Smart Biotech Scientist:
1. Huberman Lab
2. Biotech Hangout
3. All-In with Chamath, Jason, Sacks & Friedberg
4. The Readout Loud
5. Freakonomics Radio
Smart Biotech Scientist launched 3 years ago and published 277 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on Smart Biotech Scientist include:
1. Farlan Veraitch
2. David Hardy
3. Michael Rome
4. Milan Tomic
5. Steffen Kreye
6. Yuta Lee
7. Chantale Bernatchez
8. Ron Najafi
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