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Post-Hoc Live

Endpoints News
Biotech
FDA
China
Pharmaceuticals
Trump Administration
Sarepta
ACIP
Duchenne Muscular Dystrophy
Biotechnology
Covid-19
Robert F. Kennedy Jr.
Vaccine Policy
Vinay Prasad
Most Favored Nation Pricing
Endpoints 100 Survey
Inflation Reduction Act
Biopharmaceutical Industry
Barda
Mrna Vaccines
Pharmaceutical Industry

Post-Hoc Live is an extension of Endpoints' analysis newsletter Post-Hoc — but streamed live on YouTube then brought to you here. Our reporters spend every day texting and calling sources, reading executive orders, and talking to each other in Slack. We're bringing that analysis that happens behind the scenes directly to you, and letting you in on some of our up-to-the-moment conversations. Subscr... more

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Latest Episodes

How existential are the current threats to US science? Noubar Afeyan, founder and CEO at Flagship Pioneering, joined us to point out the various landmines dotting the landscape during a live taping of Post-Hoc Live out at the JP Morgan Healthcare Con... more

It was a chaotic first year for this Trump administration’s FDA. The agency is down thousands of staff. Leadership was unstable. Industry insiders say they worry about the regulatory environment. What’s next? We’re joined by Holly Fernandez Lynch, an... more

The Endpoints newsroom has spent the past few weeks taking stock of the year and picking our 2025 biopharma winners and losers. Who (or what) was up, down, or on the rebound in 2025? We’ll reveal our picks and send you off into the holidays in style.... more

Derek Lowe is one of the biopharma industry’s most prolific commentators — in just the past month, he’s written about generic drug manufacturing, Sarepta, and the TrkB receptor in his column, In the Pipeline. He joins Post-Hoc Live to talk about the ... more

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Recent Guests

Holly Fernandez Lynch
Assistant Professor of Medical Ethics and FDA expert
University of Pennsylvania
Episode: Fewer drugs, more chaos: One year under the new FDA
Zach Brennan
Senior Editor covering the FDA
Endpoints News
Episode: Fewer drugs, more chaos: One year under the new FDA
Andy Dunn
Biotech Correspondent
Endpoints News
Episode: Biopharma’s Winners and Losers of 2025
Lydia Ramsey-Flander
Health Tech Lead
Endpoints News
Episode: Biopharma’s Winners and Losers of 2025
Derek Lowe
Chemist, columnist, and blogger known for his insights in biopharma.
In the Pipeline blog
Episode: Reality check-ing biotech — with Derek Lowe
Hannah Kuchler
Global Pharma Editor at the Financial Times
Financial Times
Episode: M&A, MFN, and the view from the UK — with the FT’s Hannah Kuchler
Kiran Musunuru
University of Pennsylvania scientist involved in CRISPR gene editing
University of Pennsylvania
Episode: The plan to make more custom CRISPR therapies — w Kiran Musunuru & Rebecca Ahrens-Nicklas
Rebecca Ahrens-Nicklas
Pediatrician at Children's Hospital of Philadelphia involved in CRISPR developments
Children's Hospital of Philadelphia
Episode: The plan to make more custom CRISPR therapies — w Kiran Musunuru & Rebecca Ahrens-Nicklas
Evan Seigerman
Head of Healthcare Research at BMO Capital Markets
BMO Capital Markets
Episode: The fight over Metsera

Host

Drew Armstrong
Executive Editor of Endpoints News and your host today, bringing insightful analysis of the evolving biopharmaceutical landscape and guiding discussions with industry experts.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#182
Hong Kong/News
Apple Podcasts
#204
Ireland/News

Talking Points

Recent interactions between the hosts and their guests.

Biopharma’s Winners and Losers of 2025
Q: What do you think that tells us about where this is all going regarding gene editing technologies?
There is anticipation for regulatory clarity on how to speed treatments like gene editing forward, especially as seen with Baby KJ.
Biopharma’s Winners and Losers of 2025
Q: What do you think Pfizer is hoping for as a bit of a holiday present out of this thing?
Pfizer is pretty confident and is hoping for successful trials next year in obesity, having seen data that gives them confidence.
The plan to make more custom CRISPR therapies — w Kiran Musunuru & Rebecca Ahrens-Nicklas
Q: What have you proposed to the FDA to streamline this process?
The researchers proposed leveraging preclinical IND-enabling studies for multiple mutations to save resources and time while ensuring safety.
Zooming out on AI in biopharma — with Vijay Pande
Q: How has your investing philosophy changed over the past decade?
I've become more excited by consumer-directed healthcare, recognizing its potential for preventative health and aligning incentives.
Zooming out on AI in biopharma — with Vijay Pande
Q: What have you been up to these last few months?
I'm in the process of building a new venture capital firm, VZVC, continuing my work in AI and healthcare investment.

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Frequently Asked Questions About Post-Hoc Live

What is Post-Hoc Live about and what kind of topics does it cover?

Featuring in-depth conversations surrounding the biopharmaceutical landscape, there is a strong focus on various aspects of biotechnology, including drug development, regulatory challenges, and the influences of market dynamics. Key topics often addressed involve artificial intelligence in healthcare, personalized medicine approaches like CRISPR, and significant trends such as mergers and acquisitions within the pharma sector. The discussions frequently highlight insights from experts in the field, offering listeners a unique perspective on current controversies, future innovations, and strategic considerations impacting the industry.

Where can I find podcast stats for Post-Hoc Live?

Rephonic provides a wide range of podcast stats for Post-Hoc Live. We scanned the web and collated all of the information that we could find in our comprehensive podcast database. See how many people listen to Post-Hoc Live and access YouTube viewership numbers, download stats, audience demographics, chart rankings, ratings, reviews and more.

How many listeners does Post-Hoc Live get?

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How many subscribers and views does Post-Hoc Live have?

To see how many followers or subscribers Post-Hoc Live has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to Post-Hoc Live?

These podcasts share a similar audience with Post-Hoc Live:

1. The Readout Loud
2. BioCentury This Week
3. Dwarkesh Podcast
4. Conversations with Tyler
5. Marketplace

How many episodes of Post-Hoc Live are there?

Post-Hoc Live launched 7 months ago and published 31 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Post-Hoc Live?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for Post-Hoc Live?

Rephonic pulls ratings and reviews for Post-Hoc Live from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.

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What guests have appeared on Post-Hoc Live?

Recent guests on Post-Hoc Live include:

1. Holly Fernandez Lynch
2. Zach Brennan
3. Andy Dunn
4. Lydia Ramsey-Flander
5. Derek Lowe
6. Hannah Kuchler
7. Kiran Musunuru
8. Rebecca Ahrens-Nicklas

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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