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pharmaphorum Podcast

pharmaphorum
Artificial Intelligence
Clinical Trials
Drug Development
Drug Discovery
Pharmaceutical Industry
Life Sciences
Digital Health
Rare Diseases
AI In Healthcare
Drug Pricing
Oncology
Patient Care
Obesity
Healthcare
Glp-1
Cancer Treatment
Frontiers Health
Mental Health
FDA
NHS

pharmaphorum is one of the leading global channels for insight into the pharma and healthcare industry – and is essentially a group of passionate people who like asking excellent questions. Our podcasts offer a chance to pose some of these questions to the keenest minds in our industry to look at the big issues and opportunities facing pharma, biotech and healthcare today. With interviews and cont... more

PublishesWeeklyEpisodes350Founded8 years ago
Number of ListenersCategories
Life SciencesHealth & FitnessScienceMedicine

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Latest Episodes

The drug price negotiation provisions in the Inflation Reduction Act were designed to continue evolving with each passing year. As CMS prepares for 2028 and 2029, the agency has put out new draft guidance codifying and, in some cases, modifying the f... more

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SYNGAP1-related disorder negatively impacts synaptic signalling during critical periods of brain development, leading to a range of cognitive, epileptic, behavioural, and motor symptoms.

In a new episode of the pharmaphorum podcast, web editor Nicol... more

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The M&A market has been rebounding in the US, driven by factors like patent cliffs and improved balance sheets – but the question is whether this will play out in Europe and how the wave could differ.

In a new pharmaphorum podcast, web editor Nicole... more

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Purespring Therapeutics is a precision nephrology company pioneering first-in-class, targeted genetic therapies designed to preserve kidney function.

In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Haseeb Ahmad, CEO of Puresprin... more

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Recent Guests

Kelly Gold
Chief Financial Officer at CAMP4 Therapeutics
CAMP4 Therapeutics
Episode: CAMP4 on a new class of ASO in gene under expression
Andrea Carta Mantiglia
Partner and lead of the Healthcare & Life Sciences Focus Team at BonelliErede
BonelliErede
Episode: BonelliErede on M&A in Europe: Andrea Carta Mantiglia
Haseeb Ahmad
CEO of Purespring Therapeutics
Purespring Therapeutics
Episode: Purespring on nephrology & gene therapy in kidney disease
Paul Bridges
President of Consulting at Parexel
Parexel
Episode: Parexel: Flawless execution, policy shifts & patient-centric design
Charlotte Moser
Chief Medical Officer at Parexel
Parexel
Episode: Parexel: Flawless execution, policy shifts & patient-centric design
Leonard Mazur
CEO and Chairman of Citius Pharmaceuticals
Citius Pharmaceuticals
Episode: Citius’ Leonard Mazur talks targeted immune therapy for CTCL
Andrew Cavey
CEO of ITM
ITM
Episode: Radiopharma in 2026 & beyond, with ITM's Dr Andrew Cavey
Rebecca Guntern
Chief Commercial Officer at Sandoz
Sandoz (Novartis division)
Episode: Biosimilars & patient access independent of geographies or socioeconomics, with Rebecca Guntern
Lee-Ann Farrell
Head of Government Affairs and National Programs at Johnson & Johnson
Johnson & Johnson
Episode: Towards a healthier world: Momentum in UK health system transformation, with Lee-Ann Farrell

Host

Nicole Raleigh
Web editor and host of the pharmaphorum podcast; has guided conversations with industry leaders across pharma, biotech, and health policy.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Policy in Focus: What’s new with CMS drug price negotiation, with Alice Valder Curran
Q: How does the small biotech exemption work, and what are the implications for acquisitions?
A small biotech drug is exempt from negotiation until IPAY 2029 if it meets two tests: it accounts for less than 1% of total Medicare expenditures and it represents a small share of the company's Medicare revenue. If such a company is acquired by a larger entity, the exemption can be lost under certain circumstances, potentially changing the pricing dynamics of the deal.
Policy in Focus: What’s new with CMS drug price negotiation, with Alice Valder Curran
Q: Why is CMS issuing a proposed rule for IPAY 2029 now, and how does that relate to the earlier guidance?
Because when Congress enacted the IRA, the first three years of the program (2026–2028) were to be implemented via guidance, not regulation. With IPAY 2029, CMS must regulate to set the standards, since a formal rulemaking is required by law for that year.
Purespring on nephrology & gene therapy in kidney disease
Q: What are your lead programs and how do they address both monogenic and non-monogenic kidney diseases?
Lead candidate PS002 targets IgA nephropathy by delivering complement factor I locally to modulate the inflammatory cascade; future candidates target monogenic conditions like Alport syndrome and steroid-resistant nephrotic syndrome, aiming to provide disease-modifying or potentially curative therapies where none exist today.
Purespring on nephrology & gene therapy in kidney disease
Q: Could you explain the core concept of the GlomThera platform and why targeting podocytes matters in kidney disease?
The platform enables direct, local delivery of genetic material to podocytes, which are crucial for filtration and glomerular health. Because podocytes are terminally differentiated, delivering a therapeutic gene can produce durable effects with a lower systemic dose, potentially improving safety and efficacy.
Radiopharma in 2026 & beyond, with ITM's Dr Andrew Cavey
Q: Could you explain ITM's pipeline and the significance of ITM 11 and ITM 31?
ITM has a broad pipeline with ITM 11 moving toward FDA decision and potential commercial launch, and ITM 31 in glioblastoma delivering therapy directly into the surgical cavity to address relapse, alongside other early-stage programs targeting novel cancers and isotopes.

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Frequently Asked Questions About pharmaphorum Podcast

What is pharmaphorum Podcast about and what kind of topics does it cover?

The shown episodes indicate a focus on biotech and pharma with an emphasis on real-world impact, from targeted cancer therapies and radiopharmaceuticals to biosimilars, patient access, and health-system transformation. Interviews frequently center on scientific advances alongside practical commercialization, policy, and operational considerations—covering clinical development, manufacturing, regulation, market access, and the evolving role of AI and data in planning, launch, and collaboration. Notable throughlines include the shift of novel therapies toward broader patient access, the tension between innovation and cost, and the growing importance of AI-enabled decision making across the drug life cycle. Overall, the lineup tends to attract... more

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Which podcasts are similar to pharmaphorum Podcast?

These podcasts share a similar audience with pharmaphorum Podcast:

1. Up First from NPR
2. The Daily
3. ThinkData Podcast
4. On with Kara Swisher
5. The Heart of Healthcare | A Digital Health Podcast

How many episodes of pharmaphorum Podcast are there?

pharmaphorum Podcast launched 8 years ago and published 350 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on pharmaphorum Podcast?

Recent guests on pharmaphorum Podcast include:

1. Kelly Gold
2. Andrea Carta Mantiglia
3. Haseeb Ahmad
4. Paul Bridges
5. Charlotte Moser
6. Leonard Mazur
7. Andrew Cavey
8. Rebecca Guntern

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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