Rephonic
Artwork for Owl Posting
Machine Learning
Cryogenic Electron Microscopy
Microbial Genomes
Computational Biology
DNA Protection Mechanisms
Genome Stability
Aging
Cancer Prevention
Somatic Mutations
Protein Dynamics
Cryopreservation
Genomic Language Models
Tissue Engineering
Vaccine Development
Biotechnology
Alphafold
Transplantation
Organ Replacement
Glioblastoma
Coherence Neuro

a podcast about the intersection of biology and computation. all episodes on www.owlposting.com/s/podcast! www.owlposting.com

PublishesTwice monthlyEpisodes9Founded2 years ago
Number of ListenersCategories
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Artwork for Owl Posting

Latest Episodes

This is an interview with Matthew Osman and Fabio Boniolo, the co-founders of Polyphron.

The thesis behind Polyphron is equal parts nauseating and exciting in how ambitious it is: growing ex-vivo tissue to use in organ repair.

And, truthfully, it f... more

Note: Thank you to rush.cloud and latch.bio for sponsoring this episode!

Rush is augmenting drug discovery for all scientists with machine-driven superintelligence.

LatchBio is building agentic scientific tooling that can analyze a wide range of sc... more

Sponsor note: the supporter of this video is rush.cloud. If you are at all involved with doing preclinical drug discovery and would benefit from computational tools, you should check out their platform + beautiful website here: rush.cloud.

If you’re... more

Key Facts

Accepts Guests
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Recent Guests

Ben Woodington
Co-founder of Coherence Neuro, electrical engineer focusing on implantable neuromodulation devices for cancer
Coherence Neuro
Episode: Neurotechnology? For Cancer? (Ben Woodington & Elise Jenkins)
Elise Jenkins
Co-founder of Coherence Neuro, oncologist/electrophysiology-informed clinician-scientist
Coherence Neuro
Episode: Neurotechnology? For Cancer? (Ben Woodington & Elise Jenkins)
Alan Tomusiak
Founder and CEO of Permanence Bio, with a PhD in the biology of aging from the USC Buck Institute.
Permanence Bio
Episode: The DNA protection company (Alan Tomusiak, Ep #4)
Dr. Sergey Ovchinnikov
A recent biology professor at MIT and a leading figure in machine learning-assisted protein engineering.
MIT
Episode: What could Alphafold 4 look like? (Sergey Ovchinnikov, Ep #3)

Host

Host
Host of Owl Posting

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#242
United States/Science/Nature
Apple Podcasts
#231
France/Science/Nature
Apple Podcasts
#33
India/Science/Nature
Apple Podcasts
#61
South Korea/Science/Nature
Apple Podcasts
#132
Denmark/Science/Nature
Apple Podcasts
#200
Switzerland/Science/Nature

Talking Points

Recent interactions between the hosts and their guests.

Neurotechnology? For Cancer? (Ben Woodington & Elise Jenkins)
Q: What milestones did you set to prove this concept could scale into a company, and how did you validate the path to humans?
The team focused first on clinician and patient engagement to establish demand, then progressed through safety and animal studies, before moving to first-in-human safety trials, with plans for early feasibility studies to demonstrate clinical and diagnostic benefits and to collect real-world data.
Neurotechnology? For Cancer? (Ben Woodington & Elise Jenkins)
Q: Could you talk a little more about the blocking regime and how you think it might affect cancer growth?
Blocking involves delivering stimulation at a high rate so neurons cannot repolarize, keeping them in a depolarized state and preventing action potentials. This perturbation, when applied to tumor-adjacent neural networks, is hypothesized to disrupt the cancer's electrical activity and potentially slow growth or alter tumor behavior.
Neurotechnology? For Cancer? (Ben Woodington & Elise Jenkins)
Q: Ben and Elise, welcome to the podcast. What exactly does Soma do and how does it compare to existing approaches like Optune?
Soma is a tiny, implantable device that sits in the skull, delivers electrical stimulation to tumor tissue, and records electrical activity for readouts. It offers closer contact to the tumor, recording capabilities, and a broader neuromodulation approach than Optune, which is external and relies on lower-density fields. Soma aims to be more targeted, smaller, and capable of longitudinal biomarker readouts.
How do you make a 250x better vaccine at 1/10 the cost? Develop it in India. (Soham Sankaran, Ep #2)
Q: What do you see as the future of PopVax in regards to expanding into other areas?
PopVax aims to leverage their platform for diseases beyond vaccines, such as cancer and autoimmune conditions, but will always prioritize vaccines.
How do you make a 250x better vaccine at 1/10 the cost? Develop it in India. (Soham Sankaran, Ep #2)
Q: What are PopVax's key innovations in vaccine design?
PopVax employs an engineering approach with mRNA-encoded display on self-assembling particles and precision immunogen design.

Audience Metrics

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Frequently Asked Questions About Owl Posting

What is Owl Posting about and what kind of topics does it cover?

Episodes cover a range of topics at the intersection of biology and computation, with a strong emphasis on innovative technologies and methodologies. Themes include tissue engineering, cryopreservation techniques for organ preservation, microbial genomics, and the impact of machine learning on protein modeling. The unique perspectives from various experts in biology and computational science reveal how these fields converge to address complex biological challenges and improve health outcomes. Engaging and informative discussions often highlight real-world applications and future directions in scientific research, making it appealing to listeners interested in the latest advancements in life sciences and technology.

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Which podcasts are similar to Owl Posting?

These podcasts share a similar audience with Owl Posting:

1. Dwarkesh Podcast
2. Conversations with Tyler
3. The a16z Show
4. Google DeepMind: The Podcast
5. Odd Lots

How many episodes of Owl Posting are there?

Owl Posting launched 2 years ago and published 9 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Owl Posting?

Recent guests on Owl Posting include:

1. Ben Woodington
2. Elise Jenkins
3. Alan Tomusiak
4. Dr. Sergey Ovchinnikov

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