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Artwork for Mendelspod Podcast

Mendelspod Podcast

Theral Timpson
Genomics
Precision Medicine
Proteomics
Illumina
Genomic Medicine
Artificial Intelligence
Genetic Testing
Drug Development
Oncology
Cancer
Liquid Biopsy
Synthetic Biology
Biotechnology
CRISPR
Single-Cell Genomics
Aging
Rare Diseases
Cancer Treatment
Iconpcr
Epigenetics

Offering a front row seat to the Century of Biology, veteran podcast host Theral Timpson interviews the who's who in genomics and genomic medicine. www.mendelspod.com

PublishesTwice weeklyEpisodes556Founded11 years ago
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NewsNatural SciencesTech NewsScience

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Artwork for Mendelspod Podcast

Latest Episodes

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com

For the past decade, liquid biopsy has largely been defined by oncology. Tumors shed DNA carrying mutations and epigenetic changes which allows researchers to detect ca... more

The future of genomics has arrived in Abu Dhabi.

On today’s show, Dr. Mohamed Alameri of the UAE Department of Health and Albarah El-Khani of M42 describe one of the most ambitious precision medicine efforts underway anywhere in the world: the Emira... more

On today’s show, Dr. Ryan Flynn of Harvard Medical School and Boston Children’s Hospital takes us into a newly emerging layer of biology: the architecture of the cell surface itself. Flynn first gained attention for the discovery of glycoRNA — RNA mo... more

For decades, biology has been driven by the powerful notion that if we could sequence enough genomes, transcriptomes, epigenomes, then we could finally explain the cell. On today’s show, Gary Schroth, the Chief Scientific Officer at Cellanome, argues... more

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Recent Guests

Gary Schroth
Chief Scientific Officer at Cellanome
Cellanome
Episode: Gary Schroth on Connecting Cellular Behavior to the Transcriptome
Phil Febbo
Chief Medical and Scientific Officer at Veracyte
Veracyte
Episode: Two-Thirds of High-Risk Breast Cancer Patients May Avoid Chemotherapy According to Veracyte Data Presented at ASCO
John Leite
Chief Commercial Officer at Veracyte
Veracyte
Episode: Two-Thirds of High-Risk Breast Cancer Patients May Avoid Chemotherapy According to Veracyte Data Presented at ASCO
Rita Shaknovich
Chief Medical Officer for the Life Sciences and Diagnostics Division at Agilent
Agilent Technologies
Episode: Building the Diagnostic Layer of Modern Cancer Care with Rita Shaknovich and Karina Kulangara of Agilent
Karina Kulangara
Associate Vice President of R&D in Companion Diagnostics at Agilent
Agilent Technologies
Episode: Building the Diagnostic Layer of Modern Cancer Care with Rita Shaknovich and Karina Kulangara of Agilent
Eric Green
Chief Medical Officer at Illumina
Illumina
Episode: Mapping the Multi-Omic Era with Eric Green of Illumina
Yan Zhang
President of Proteomic Sciences at Thermo Fisher Scientific
Thermo Fisher Scientific
Episode: Inside Proteomics at Thermo Fisher with Yan Zhang
Rob Osborne
Senior Vice President of R&D at Biomodal
Biomodal
Episode: Separating Epigenetic Signals Improves Early Cancer Detection with Rob Osborne, Biomodal
Irina Babina
CEO of Concr
Concr
Episode: Digital Controls for Cancer Drug Trials? Irina Babina, Concr

Host

Theral Timpson
Host of Mendelspod Podcast

Reviews

4.5 out of 5 stars from 55 ratings
  • Great views into high science

    As a fractional CFO at BluePrint CPAs, I find the technical aspects of the shows help me dive into the fast-paced world of life sciences.

    Apple Podcasts
    5
    BluePrint CPAs
    Canada4 years ago
  • Fascinating content!

    No matter the subject, you’re guaranteed to learn something from every episode - can’t recommend Mendelspod enough! 🙌

    Apple Podcasts
    5
    Arlie K
    United States5 years ago
  • Great podcast if you’re into life science

    Great interviews and panelists. In depth and entertaining.

    Apple Podcasts
    5
    111CooperDale
    United States6 years ago
  • Informative Listen

    Informative, up-to-date commentary and interviews delivered by a knowledgable, engaging and entertaining host.

    Apple Podcasts
    5
    B-111
    United Kingdom7 years ago
  • Interesting subject, bad interviewer

    There are some great guests but Theral interrupts them often to put in his own 'two cents'. Let your guests tell their story!

    Apple Podcasts
    2
    smlmbrt
    Canada9 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Mix of praise for depth and some critique of host pacing or interruptions
Content is up-to-date and practically informative for biotech strategy
Guests are often top-tier, with rigorous questions from the host
Insightful discussions pairing high science with industry context
Some listeners wish for smoother moderation and more guest-led dialogue

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Building the Diagnostic Layer of Modern Cancer Care with Rita Shaknovich and Karina Kulangara of Agilent
Q: What are companion diagnostics and how has the concept evolved with precision medicine?
Companion diagnostics are tests that identify which patients will benefit from a particular drug, evolving from immunohistochemistry-based approaches to more complex, multi-omic strategies that integrate proteins, DNA, and RNA. This evolution aims to improve patient selection, predict responses, and ultimately enhance outcomes while aligning with regulatory pathways.
The Case for a 6-Base Genome with Peter Fromen, CEO of Biomodal
Q: What makes Biomodal's six-base genome different from previous epigenetic approaches?
It reads three layers of information directly from each cytosine base—unmethylated, 5-methylcytosine, and 5-hydroxymethylcytosine—within a single workflow, avoiding the noise and imputation issues of bisulfite-based methods and enabling more precise, early-disease detection.
Beyond GLP-1: Why Peptides Are Back at the Center of Drug Discovery with Charlie Johannes and Tomi Sawyer
Q: What has driven peptide drug discovery back into the limelight?
It's the combination of longer-acting peptides enabled by lipid modifications, improved oral delivery approaches, and new tools that let us engineer properties directly into peptides, expanding the feasible pharmacology beyond what was possible a decade ago.
Illumina's New Mapped Read Technology Provides Insights into Rare Disease: Stephen Kingsmore, Olivia Kim-McManus and Ali Crawford
Q: What impact does this technology have on designing therapeutics?
It allows for targeted therapies to be developed based on precise genomic information, tailored to individual patient needs.
Illumina's New Mapped Read Technology Provides Insights into Rare Disease: Stephen Kingsmore, Olivia Kim-McManus and Ali Crawford
Q: What biological problems are you addressing with proximity-mapped read technology?
This technology resolves complex genome structures, previously difficult to interpret with short read sequencing, particularly for identifying elusive genetic variants.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Mendelspod Podcast

What is Mendelspod Podcast about and what kind of topics does it cover?

The show consistently centers on cutting-edge biology, genomics, and biomedical innovation, with episodes spanning Bayesian modeling in oncology, six-base genomics, spatial transcriptomics, MRD and genomic medicine adoption, aging biology, and peptide therapeutics. Guests include lab scientists, biotech founders, and industry leaders, often pairing deep technical explanations with practical implications for clinical practice, drug development, and health systems. A notable strength is bridging laboratory advances with real-world applications, from diagnostics and therapy design to regulatory and reimbursement considerations, making it a strong resource for researchers, investors, and decision-makers seeking the latest in genomic medicine an... more

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1. The Long Run with Luke Timmerman
2. Dwarkesh Podcast
3. Freakonomics Radio
4. The a16z Show
5. Odd Lots

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Mendelspod Podcast launched 11 years ago and published 556 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Mendelspod Podcast?

Recent guests on Mendelspod Podcast include:

1. Gary Schroth
2. Phil Febbo
3. John Leite
4. Rita Shaknovich
5. Karina Kulangara
6. Eric Green
7. Yan Zhang
8. Rob Osborne

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