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Let's Talk Quality

Hemish Ilangaratne
Quality Assurance
Biotechnology
Pharmaceutical Industry
Leadership
Cell Therapy
Career Development
Gene Therapy
Regulatory Affairs
Patient Safety
Biotech Industry
Leadership Development
Clinical Trials
Cell and Gene Therapy
Quality Leadership
Quality Control
Compliance
Pharmaceuticals
Drug Development
Car-T Cell Therapy
Mentorship

“Let’s Talk Quality” is a podcast that seeks to shine a light on quality assurance, a profession that acts as the cornerstone for bringing safer medicine to patients. For life science companies to continue to develop life-saving medicines, a culture of good quality must be driven across the industry, whether that be an early phase gene therapy biotech or a global pharma organisation. This podcast ... more

PublishesWeeklyEpisodes70Founded3 years ago
Number of ListenersCategories
Life SciencesScienceCareersBusiness

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Artwork for Let's Talk Quality

Latest Episodes

The non-linear path is often the most powerful one.

Cinta Burgos on Building a Career Across Functions, Modalities, and Mindsets.

In today's episode I was joined by Cinta Burgos, Senior Vice President of Quality and Regulatory CMC at New Amsterdam ... more

From a graveyard shift in a generic drug lab to leading quality for one of the most advanced cell therapy programs on the planet - Mike Ruane's story is one every quality professional needs to hear.

In today's episode I was joined by Mike Ruane, Hea... more

YouTube

CAR-T Saved Her Life. Why Can’t Most Patients Access It?

In today’s episode I was joined by Laurie Adami, cancer survivor, patient advocate, and one of the most impactful voices I’ve had on the podcast.

I first spoke to Laurie a couple of years ago... more

YouTube

Perseverance, perspective and people-first leadership in a global quality role.

In today's episode I was joined by Burak Begen, Head of Global Manufacturing Quality at Siemens Healthineers.

I really wanted to speak to Burak because he’s built his c... more

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Recent Guests

Mike Ruane
Head of quality at Bristol Myers Squibb for in vivo CAR T
Bristol Myers Squibb
Episode: From the Graveyard Shift to the Frontier of Cell Therapy, with Mike Ruane
Laurie Adami
Cancer survivor, patient advocate, memoir author
Episode: Laurie Adami on Life After CAR-T, and the Reality Patients Still Face
Burak Begen
Head of Global Manufacturing Quality, Siemens Healthineers
Siemens Healthineers
Episode: How to Drive KPI's the Right Way in Global Quality, with Burak Begen
Melodie Bryce
Chief Quality Officer for Kincell Bio
Kincell Bio
Episode: Developing Future A-Player Quality Leaders, with Melodie Bryce
Rex Ready
Head of quality at Bebio (Bbio)
Bbebio/Bebio
Episode: Lessons from Building Quality in Start-Up Cell Therapy, with Rex Ready
Dennis Rodman
Senior Director, Quality Management Systems and Digital Compliance at Intellia Therapeutics
Intellia Therapeutics
Episode: What Good Digital Transformation in Quality Actually Looks Like, with Dennis Rodman
Valerie Brown
Quality professional with experience across labs, CDMOs, Gilead, and Thermo Fisher
Thermo Fisher Scientific
Episode: Problem Solving, Partnerships, and Putting Yourself Out of Your Comfort Zone, with Valerie Brown
Dana Adcock
Quality leader and consultant with decades of experience in the quality assurance sphere.
Episode: Overcoming Self-Doubt in Quality Leadership, with Dana Adcock
Anthony Mire-Sluis
Currently head of Global Quality for Operations at Gilead.
Gilead
Episode: Designing Future-Ready Quality Organisations in the Digital Age with Anthony Mire-Sluis

Hosts

Hamish
Host of the podcast
Hemish Alangaratney
Co-host and longtime host of Let's Talk Quality

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

From the Graveyard Shift to the Frontier of Cell Therapy, with Mike Ruane
Q: What early career decisions set you up for later opportunities?
He emphasizes embracing diverse roles within the same organization through mergers and acquisitions, and taking on new programs (like CAR-T) even when unfamiliar, as long as you build a solid quality foundation and problem-solving mindset.
Laurie Adami on Life After CAR-T, and the Reality Patients Still Face
Q: What do you see as the biggest bottlenecks to CAR-T access today?
Laurie argues that awareness and insurance are the primary bottlenecks; she notes that greater understanding of CAR-T's effectiveness could drive referrals to appropriate specialists, but many community oncologists lack familiarity with CAR-T and access remains uneven due to cost, networks, and regulatory complexity.
Laurie Adami on Life After CAR-T, and the Reality Patients Still Face
Q: How are you today? How does life actually feel like now compared to where you were back then?
Laurie describes being eight years post-CAR-T, in complete remission, but still managing long-term side effects from prior treatments and chemotherapy, with ongoing advocacy and writing, while emphasizing that life after CAR-T is not simply 'cured'—there are persistent health challenges and a need for continued medical progress.
How to Drive KPI's the Right Way in Global Quality, with Burak Begen
Q: What are the key challenges of managing a global site quality role across time zones?
Key challenges include coordinating across time zones, cultural differences, and maintaining engagement and clarity of KPIs, which Burak addresses by empowering teams and setting upfront decision boundaries.
How to Drive KPI's the Right Way in Global Quality, with Burak Begen
Q: And why quality? What was it about quality that you loved that made you think, this is my career, I want to become a quality leader?
Burak explains that quality started as the first available job, but he grew to enjoy helping people and aligning with partners rather than policing them, which shaped his leadership approach.

Audience Metrics

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Frequently Asked Questions About Let's Talk Quality

What is Let's Talk Quality about and what kind of topics does it cover?

The show centers quality leadership in life sciences, with episodes featuring senior quality executives, regulators, and transformation leaders. Across conversations, listeners get practical strategies for building and sustaining quality cultures in startups and large organizations, implementing digital tools and AI in regulated environments, and aligning quality with patient safety, regulatory expectations, and business goals. Guests frequently discuss leadership development, cross-functional collaboration, inspection readiness, and scaling quality systems in biotech, cell therapy, and pharma, often with a focus on startup growth, regulatory readiness, and modernizing quality through technology. A notable strength is bringing real-world, b... more

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Which podcasts are similar to Let's Talk Quality?

These podcasts share a similar audience with Let's Talk Quality:

1. Hidden Brain
2. TED Radio Hour
3. This American Life
4. The Weekly Show with Jon Stewart

How many episodes of Let's Talk Quality are there?

Let's Talk Quality launched 3 years ago and published 70 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Let's Talk Quality?

Recent guests on Let's Talk Quality include:

1. Mike Ruane
2. Laurie Adami
3. Burak Begen
4. Melodie Bryce
5. Rex Ready
6. Dennis Rodman
7. Valerie Brown
8. Dana Adcock

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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