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Let's Talk Alzheimer's

BrightFocus Foundation
Alzheimer's Disease
Pointer Study
Brightfocus Foundation
Clinical Trials
Multidomain Lifestyle Intervention
Finger Study

Welcome to Let’s Talk Alzheimer’s, your place to go for trusted insights from leading scientists and medical experts. Get the latest information on diagnosis, risk reduction, clinical trials, and the latest treatments. Presented by BrightFocus Foundation's Alzheimer's Disease Research program.

PublishesDailyEpisodes3Founded2 months ago
Number of ListenersCategories
MedicineScienceHealth & Fitness

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Artwork for Let's Talk Alzheimer's

Latest Episodes

Can everyday lifestyle choices really protect your memory? Dr. Laura Baker, professor at Wake Forest University School of Medicine, shares insights from the groundbreaking U.S. POINTER trial—the largest study of its kind exploring how lifestyle chang... more

Detecting subtle changes in memory or thinking can be unsettling, but understanding what’s behind those changes can lead to critical early diagnosis—or even rule out Alzheimer’s altogether. In this episode, behavioral neurologist Dr. Sharon Cohen, me... more

Just three years ago, there were no FDA-approved treatments that targeted the underlying causes of Alzheimer’s—only medications that modified symptoms. Today, two FDA-approved therapies—Leqembi (lecanemab) and Kisunla (donanemab)—clear amyloid protei... more

A quick peek into the world of Let's Talk Alzheimer's - stay tuned for more.

Key Facts

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Number of Listeners
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Recent Guests

Dr. Laura Baker
Professor of gerontology and geriatric medicine
Wake Forest University School of Medicine
Episode: Lifestyle & Brain Health: U.S. POINTER Study | Dr. Laura D. Baker
Sharon Cohen
Neurologist, memory director of the Toronto Memory Program
Toronto Memory Program
Episode: Detecting Alzheimer’s: How to Recognize Early Signs | Dr. Sharon Cohen
Armen Moughamian
A cognitive neurologist and medical director at the Ray Dolby Brain Health Center
California Pacific Medical Center and Sutter Health
Episode: Leqembi & Kisunla: New Alzheimer's Treatments Explained | Dr. Armen J. Moughamian

Chart Rankings

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Talking Points

Recent interactions between the hosts and their guests.

Detecting Alzheimer’s: How to Recognize Early Signs | Dr. Sharon Cohen
Q: From the listeners, how can family members approach a loved one who seems to be forgetting things without causing defensiveness?
Lead with concern, not accusation, frame it as a shared concern for safety and well-being, and propose a medical evaluation while offering support and understanding.
Lifestyle & Brain Health: U.S. POINTER Study | Dr. Laura D. Baker
Q: How was the US Pointer study designed and how many participants were involved?
The study enrolled about 2,000 participants across five regions, randomized to either a self-guided program or a more structured, highly accountable plan. Both groups focused on four lifestyle pillars, with the structured group meeting more frequently and receiving closer accountability, which yielded greater cognitive benefits over two years.
Leqembi & Kisunla: New Alzheimer's Treatments Explained | Dr. Armen J. Moughamian
Q: Charles from New York asks what these can do for my wife and who is eligible?
Eligibility centers on early symptomatic Alzheimer's (mild cognitive impairment to mild dementia) with confirmation of amyloid pathology; testing and imaging are used to ensure appropriate candidates and to exclude other causes.
Leqembi & Kisunla: New Alzheimer's Treatments Explained | Dr. Armen J. Moughamian
Q: Mary from Minnesota asks, how do these drugs work for Alzheimer's?
They are monoclonal antibodies that target amyloid in the brain, recruiting the immune system to remove amyloid and slow disease progression without curing it; efficacy is greater when started early in the disease.

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How many episodes of Let's Talk Alzheimer's are there?

Let's Talk Alzheimer's launched 2 months ago and published 3 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Let's Talk Alzheimer's?

Recent guests on Let's Talk Alzheimer's include:

1. Dr. Laura Baker
2. Sharon Cohen
3. Armen Moughamian

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