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Artwork for JAMA Otolaryngology–Head & Neck Surgery Author Interviews

JAMA Otolaryngology–Head & Neck Surgery Author Interviews

JAMA Network
Head and Neck Cancer
Circulating Tumor DNA
Hearing Aids
Clinical Trials
Immunotherapy
Dysphagia
Manual Therapy
Swallowing Function
Hearing Loss
Liquid Biopsies
Head and Neck Cancers
Radiation Fibrosis
Patient Quality Of Life
Patient Outcomes
Audiology
Over-the-Counter Hearing Aids
Oropharyngeal Squamous Cell Carcinoma
Human Papillomavirus
Audio Technology
Service Models

Interviews with authors of articles from JAMA Otolaryngology–Head & Neck Surgery. JAMA Otolaryngology–Head & Neck Surgery is a peer-reviewed medical journal that provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinica... more

PublishesMonthlyEpisodes114Founded9 years ago
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MedicineScienceHealth & Fitness

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Artwork for JAMA Otolaryngology–Head & Neck Surgery Author Interviews

Latest Episodes

Interview with Amal Isaiah, MD, PhD, MBA, author of Deep Learning in Otolaryngology: A Narrative Review, and Matthew A. Shew, MD, MSCI, author of Shifting the AI Questions in Otolaryngology From "Can We Build a Model?" to "Will It Improve Patient Car... more

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Interview with Baran D. Sumer, MD, and Lauren Gabra, MD, authors of Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer. Hosted by Paul C. Bryson, MD, MBA. Related Content:

• Body Mass Index and Nutritional S... more

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Interview with Matthew G. Crowson, MD, MPA, MASc, MBI, author of Federal Funding in Otolaryngology–Head and Neck Surgery—When It Mattered. Hosted by Paul C. Bryson, MD MBA . Related Content:

• Federal Funding in Otolaryngology–Head and Neck Surger... more

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Interview with Trisha M. Wise-Draper, MD, PhD author of Amivantamab for Recurrent or Metastatic Adenoid Cystic Carcinoma: A Phase 2 Nonrandomized Clinical Trial. Hosted by Paul C. Bryson, MD MBA. Related Content:

• Amivantamab for Recurrent or Met... more

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Recent Guests

Lauren Gabra
Otolaryngology head and neck surgery resident involved in the study
UT Southwestern
Episode: Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Baran Sumer
Professor and chief of the Division of Head and Neck Oncology
UT Southwestern
Episode: Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Dr. Matthew Crowson
Assistant Professor of Otolaryngology Head and Neck Surgery; Director of Clinical Informatics and Artificial Intelligence at Mass General Brigham
Mass General Brigham
Episode: Federal Funding in Otolaryngology–Head and Neck Surgery
Trisha Wise-Draper
Professor of Medicine and Section Head of Medical Oncology
University of Cincinnati
Episode: Amivantamab for Recurrent or Metastatic Adenoid Cystic Carcinoma
Dr. Yaël Bensoussan
Assistant Professor, Chief of the Division of Laryngology, and Director of the University of South Florida's Voice Center
University of South Florida
Episode: Why Hearing Health Must Be Part of Voice Biomarker Research
Dr. Victoria Sanchez
Audiologist and Associate Professor, Chief of the Audiology Section
University of South Florida
Episode: Why Hearing Health Must Be Part of Voice Biomarker Research
Dr. Melina Windon
Assistant Professor of Otolaryngology-Head & Neck Surgery
University of Kentucky
Episode: The JAMA Otolaryngology-Head & Neck Surgery Editorial Fellowship Experience
Dr. Peter Dixon
Assistant Professor of Otolaryngology-Head & Neck Surgery
Medical University of South Carolina
Episode: The JAMA Otolaryngology-Head & Neck Surgery Editorial Fellowship Experience
Dr. Eric Kezirian
Professor in the Department of Head & Neck Surgery at the David Geffen School of Medicine at UCLA
David Geffen School of Medicine at UCLA
Episode: Anteroposterior and Lateral Epiglottis-Related Obstruction in Adult Obstructive Sleep Apnea

Host

Paul Bryson
Host of JAMA Otolaryngology–Head & Neck Surgery Author Interviews and related editorial and professional activities at Cleveland Clinic.

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Talking Points

Recent interactions between the hosts and their guests.

Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Q: What are the next steps or take-home messages for this space going forward?
The take-home is that treatment decisions should incorporate individual nutritional and immune status, and there is potential for future studies to explore timing and strategies to optimize nutrition before or during immunotherapy to improve outcomes.
Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Q: Are there practical steps clinicians could take pre-treatment to optimize nutrition for patients about to start immunotherapy?
While historical data on pre-treatment nutritional supplementation are mixed, preserving or improving nutritional status could theoretically benefit outcomes. The discussion also cover how understanding patient-level immunocompromise may influence treatment planning.
Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Q: What did you find about baseline BMI and weight changes prior to starting immunotherapy?
Baseline BMI alone did not show a significant association with outcomes, but weight loss of 2% or more before starting treatment was linked to worse outcomes, highlighting the impact of recent nutritional status on therapy effectiveness.
Body Mass Index and Nutritional Status With Immunotherapy Response in Head and Neck Cancer
Q: Can you share the population studied and how you defined immunotherapy exposure in the Flatiron database?
We used a large national cohort from the Flatiron database, including thousands of head and neck cancer patients treated with immunotherapy, defined as PD-1/PD-L1 inhibitors and CTLA-4 inhibitors, to observe potential predictors of outcomes.
Federal Funding in Otolaryngology–Head and Neck Surgery
Q: For young investigators, what does the contemporary funding pathway look like and what practical steps help accelerate proof-of-concept work?
Start with seed funding from professional societies or institutes to cover compute and small-scale studies, then use those results to build a stronger case for NIH or other major grants, while leveraging enterprise licenses to protect data.

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This show features in-depth conversations with authors and leading clinicians in otolaryngology–head & neck surgery, focusing on cutting-edge research, clinical practice patterns, and the evolving landscape of patient care. Episodes frequently explore how emerging evidence translates into practice—from hearing health and voice biomarkers to surgical innovations, immunotherapy for head and neck cancers, and novel treatment paradigms in sleep and olfactory disorders. A notable strength is the multidisciplinary approach, bringing together researchers, clinicians, and editors to discuss study design, trials, and the practical impact of research on patient outcomes. The podcast often highlights collaboration across disciplines and institutions, ... more

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1. OTO Journal
2. Head and Neck Innovations
3. BackTable ENT & Allergy
4. JAMA Medical News
5. JAMA Editors' Summary

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this podcast launched 9 years ago and published 114 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Lauren Gabra
2. Baran Sumer
3. Dr. Matthew Crowson
4. Trisha Wise-Draper
5. Dr. Yaël Bensoussan
6. Dr. Victoria Sanchez
7. Dr. Melina Windon
8. Dr. Peter Dixon

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