
🌐 1PM.WIKI 🌐 🔍 🎲 Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles. 😟 When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.
| Publishes | Weekly | Episodes | 85 | Founded | 4 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | MedicineHealth & Fitness | |||

The First Principles of Meningitis.
In this episode we breakdown the first principles, going over pathophysiology, examination differences between adults and children, diagnosis and management of Meningitis, with a focus on bacterial meningitis, th... more
Welcome to the First Principles of Medicine podcast. In this series, we break down complex medical topics into their first principles! So when the stress is on and you've been asked a tough question that you don't know the answer to in an exam, we fe... more
It's just a swollen eye… right? 👀 But when does a simple eyelid infection become a sight-threatening emergency?
In this episode, we take a first principles approach to Periorbital and Orbital Cellulitis, breaking down the anatomy, pathophysiology, ... more
Why does a clot in the lungs kill? It isn’t suffocation—it’s mechanical plumbing failure.
In this episode, we strip away all the confusing aspects surrounding Pulmonary Embolism and look at it through a first principles approach. We discuss a very f... more
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Love the 5-minute recaps and the banters in the full episode!!
Keep doing what you’re doing guys 👌🏻
As a new listener and a fellow medical student, this literally helped me understand perspectives and also enjoy just listening to different opinions on different topics.
😉
Solid podcast. Part of my commute ritual 🙏🏻
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Apple Podcasts | #118 |
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This show breaks down medical topics to first principles, using accessible explanations, practical case-thinking, and concise summaries. Episodes cover core anatomy, pathophysiology, diagnostic reasoning, and treatment pathways across diverse specialties, with a balance of didactic discussion and light banter. A standout pattern is the two-rail format: quick, digestible overviews for quick learning and deeper, anatomy-and-pathophysiology focused discussions for deeper understanding, making it helpful for students, residents, and practicing clinicians who want sharpened clinical reasoning and memorable takeaways.
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3. Harrison's PodClass: Internal Medicine Cases and Board Prep
4. OSCE Talk
5. Hamish & Andy
First Principles of Medicine launched 4 years ago and published 85 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on First Principles of Medicine include:
1. Daniel Khong
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