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Artwork for Creating Memory: Vaccines & Immunity

Creating Memory: Vaccines & Immunity

CVIMP
Vaccines
Sars-Cov-2
Vaccine Development
Immunology
Covid-19
Influenza
Mycobacterium Tuberculosis
Washington University School Of Medicine
Monoclonal Antibodies
Antibody Responses
Respiratory Syncytial Virus
Maternal-Fetal Immunology
RSV Vaccine Research
High-Affinity Antibodies
Pediatric Infectious Diseases
T Cells
Ebola
Mosaic Nanoparticle Vaccines
Influenza Virus Vaccines
Germinal Center Response

Hear from scientists working to develop new vaccines and understand immunity to microbial pathogens. Host: Larissa Thackray, Ph.D., Professor of Infectious Diseases

PublishesMonthlyEpisodes29Foundeda year ago
Number of ListenersCategories
MedicineHealth & FitnessLife SciencesScience

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Artwork for Creating Memory: Vaccines & Immunity

Latest Episodes

We talk with Dr. Julianna Han, a senior staff scientist at the Scripps Research institute, CA, who studies antibody-epitope interactions following human influenza virus infection and vaccination to inform the development of novel influenza immunogens... more

We talk with Dr. Daniel Malouli, an assistant professor at the Vaccine and Gene Therapy Institute at the Oregon Health and Science University, OR, who studies how virus-host interactions modulate CMV infection and pathogenesis as well as determine th... more

We talk with Dr. Sumanta Naik, a staff scientist in the Department of Molecular Microbiology at Washington University School of Medicine, who is investigating the role of IRGM1 in type I interferon and B cell responses following vaccination and tuber... more

We talk with Dr. Mario Feldman, Professor of Microbiology at Washington University School of Medicine in St. Louis, MO who studies the pathogenesis of Acinetobacter and the biogenesis of bacterial extracellular vesicles.

We talk with Dr. Daniel Hoft, Director of the Division of Infectious Diseases, Allergy & Immunology and the Center for Vaccine Development at Saint Louis University School of Medicine in St. Louis, MO who studies the development of T-cell targeting v... more

We talk with Dr. Michela Locci, Associate Professor of Microbiology at the University of Pennsylvania Perelman School of Medicine in Philadelphia, PA who studies how T follicular helper cells promote optimal germinal cell reactions and antibody respo... more

We talk with Dr. Namit Chaudhary, a postdoctoral researcher in the Department of Immunology & Microbiology at The Scripps Research Institute, CA, who develops new technologies to generate a safe and effective single-shot lipid nanoparticle-based HIV ... more

We talk with Dr. Zhouming Liu, an assistant professor of Molecular Microbiology at Washington University School of Medicine, MO, who studies mechanisms of La Cross virus entry and monoclonal antibody–mediated inhibition of infection.

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Recent Guests

Cassie Simonich
Pediatric infectious disease fellow at Seattle Children's Hospital
University of Washington
Episode: Episode 11: Mapping RSV evolution to infection and monoclonal antibody treatments
Alexander Cohen
Post-doctoral researcher in Pamela Bjorkman's lab at California Institute of Technology
California Institute of Technology
Episode: Episode 9: Using mosaic nanoparticle vaccines to generate broadly protective immmune responses
Seth Zost
Research instructor in the Vanderbilt Vaccine Center
Vanderbilt University Medical Center
Episode: Episode 7: Novel approaches to dissect antibody responses to respiratory viruses
Brett Case
Instructor in the Division of Infectious Diseases at Washington University School of Medicine.
Washington University School of Medicine
Episode: Episode 6: Using phylogenetic inference to design vaccine antigens
Christina Lee Stallings
Professor of Molecular Microbiology, focusing on Mycobacterium tuberculosis.
Washington University School of Medicine
Episode: Episode 5: New therapeutic strategies for treating mycobacterium tuberculosis
Robert Seder
Chief of the Cellular Immunology Section in the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases
National Institute of Allergy and Infectious Diseases
Episode: Episode 4: From AIDS to Zika
Nardhy Gomez-Lopez
Professor in the Departments of Obstetrics and Gynecology and Pathology and Immunology at Washington University School of Medicine.
Washington University School of Medicine
Episode: Episode 3: Immunobiology of pregnancy and birth
Gabriel Victora
Associate Professor and Howard Hughes Medical Institute Investigator at Rockefeller University
Rockefeller University
Episode: Episode 2: Evolution of antibodies in the germinal center
Helen Chu
Physician and professor of medicine and allergy and infectious diseases at the University of Washington
University of Washington
Episode: Episode 1: Respiratory viruses and maternal vaccines

Host

Larissa Thackray
Host of various discussions on vaccine development and immunity in infectious diseases, with a focus on current research methodologies and innovations in vaccine technology.

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Talking Points

Recent interactions between the hosts and their guests.

Episode 2: Evolution of antibodies in the germinal center
Q: What happens in the context of infection, reinfection, or a primary vaccination and subsequent vaccination?
Previous antibody responses dominate due to strong imprinting, but variant boosts can recruit new B cells.
Episode 4: From AIDS to Zika
Q: What are sort of the big remaining questions that you would like to tackle?
We have a big TB program and are looking at giving intravenous BCG completely protected animals, aiming to develop that as a vaccine for humans.
Episode 10: Designing a pipeline to enhance T cell-mediated vaccine protection
Q: What are the bigger questions you are trying to address regarding HLA, T cells, and memory immunity?
We aim to identify elements that can help us prepare better for future pandemics and find commonalities across viruses to harness T cell potential.
Episode 10: Designing a pipeline to enhance T cell-mediated vaccine protection
Q: Can you tell us a little bit about your journey and how it led you into working on viruses and immunology?
I became interested in immunology during my bachelor's and master's program, focusing on genetics and later HLA during my master thesis, leading to my fascination with the interplay between viral infections and human immunology.
Episode 11: Mapping RSV evolution to infection and monoclonal antibody treatments
Q: What are your future research plans?
I hope to balance clinical time with research, focusing on pediatric respiratory pathogens and developing preventive strategies.

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Frequently Asked Questions About Creating Memory: Vaccines & Immunity

What is Creating Memory: Vaccines & Immunity about and what kind of topics does it cover?

A dynamic exploration of vaccine development and the intricacies of immunity, featuring insights from leading scientists in the field. Topics include innovative research methods in infectious diseases, the evolution of notable pathogens, and advancements in vaccine designs tailored to combat contemporary and emerging viruses. Distinctively, the discourse bridges academic research with practical implications, aiming to enhance public understanding of vaccines and promote informed discussions around health innovations. With contributions from various experts, it serves as a vital resource for those interested in the intersection of science, health policy, and disease prevention.

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Creating Memory: Vaccines & Immunity launched a year ago and published 29 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Creating Memory: Vaccines & Immunity?

Recent guests on Creating Memory: Vaccines & Immunity include:

1. Cassie Simonich
2. Alexander Cohen
3. Seth Zost
4. Brett Case
5. Christina Lee Stallings
6. Robert Seder
7. Nardhy Gomez-Lopez
8. Gabriel Victora

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