Artwork for Best Science Medicine Podcast

Best Science Medicine Podcast - BS without the BS

James McCormack

Exercise

Fibromyalgia

Primary Care

Parkinson's Disease

Family Medicine

Systematic Reviews

Falls Prevention

Pain Management

Depression

Vitamin D

Quality Of Life

Motor Symptoms

Topical Lidocaine

Insomnia

Yeast Infections

Antifungal Treatments

Single Dose Therapy

Clinical Cure Rate

Continuity Of Care

Health Outcomes

The Best Science (BS) Medicine Podcast is a weekly presentation where practitioners can get evidence-based drug therapy content that is practical, entertaining and promotes healthy scepticism. In essence, we are the Medication Mythbusters. We present information that is useful and relevant to physicians, pharmacists, nurses, physician assistants and other health professionals, and that can easily ... more

557 ratings

Publishes	Twice monthly	Episodes	20	Founded	18 years ago
Number of Listeners		Categories	Health & FitnessMedicine

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Guests Hosts Reviews Charts Talking Points

Latest Episodes

Episode 625: Blood Pressure Measurement Technique: Meaningful mistakes or minor details?

In episode 625, Mike K and James invite Danielle Perry and Tony Nickonchuk to the podcast to talk about the evidence around blood pressure measurement techniques. You might be surprised by what does and does not influence blood pressure measurements.... more

23 Jul 2026 • 35 min • Most popular

Episode 624: PCSK9 Inhibitors: Cardiovascular prevention panacea or pricey pokes?

In episode 624, James and Mike K invite Tony Nickonchuk to go over all the new evidence we have for the PCSK9 inhibitors. First, we discuss whether or not the evidence addresses the issue of primary versus secondary prevention. We then give you all t... more

17 Jul 2026 • 26 min

Episode 623: Less than 140, 130, or 120? Counting down to the optimal systolic blood pressure target

In episode 623, Jamie and James invite Samantha Moe back again to talk about the never-ending debate as to what is the target for systolic blood pressure. We look at the evidence and then try to put it into a reasonable context because at best the ev... more

8 Jun 2026 • 25 min

Episode 622: Bronchodilator with Benefits? Budesonide-formoterol rescue inhaler for asthma

In episode 622, Jamie and James invite Émélie Braschi back again to talk about if we should be using inhalers that combine corticosteroids and beta-agonists as rescue inhalers. We go over the best available evidence and then try to put the findings i... more

30 May 2026 • 27 min

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Number of Listeners

Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Danielle Perry

Clinical evidence expert with the College of Family Physicians of Canada, member of the peer team

College of Family Physicians of Canada

Episode: Episode 625: Blood Pressure Measurement Technique: Meaningful mistakes or minor details?

Tony Nickonchuk

Clinical evidence expert for the College of Family Physicians of Canada; pharmacist

College of Family Physicians of Canada

Episode: Episode 624: PCSK9 Inhibitors: Cardiovascular prevention panacea or pricey pokes?

Samantha Moe

Clinical pharmacist and clinical evidence expert for the College of Family Physicians of Canada

College of Family Physicians of Canada

Episode: Episode 623: Less than 140, 130, or 120? Counting down to the optimal systolic blood pressure target

Mike Kolber

Professor, University of Alberta, Department of Family Medicine

University of Alberta

Episode: Episode 621: Whole-Body MRI for Cancer Screening: Many findings, little benefit

Emily Mapplethorpe

Resident involved in a quality project on whole-body MRI for screening

Unknown (resident)

Episode: Episode 621: Whole-Body MRI for Cancer Screening: Many findings, little benefit

Gavin Lowe

Radiologist in Edmonton, invited to provide radiology perspective

Radiology

Episode: Episode 621: Whole-Body MRI for Cancer Screening: Many findings, little benefit

Émélie Braschi

Doctor in Ottawa, musician advisor of DCFPC

Ottawa, Canada

Episode: Episode 618: From Nerve Pain to Knee Pain: Gabapentinoids for osteoarthritis

Jessica Kirkwood

Family doctor and associate professor

University of Alberta

Episode: Episode 616: Taking the “ouch” out of IUD insertion: Can topical lidocaine help?

Tina Karonik

Professor in the Department of Family Medicine at the University of Alberta and a family physician.

University of Alberta

Episode: Episode 611: Meds for Essential Tremor: Steady solution or shaky science?

Hosts

James McCormack

Host of the show; professor in the Faculty of Pharmaceutical Sciences, University of British Columbia; clinician-scientist

Jamie Falk

Co-host of the show; associate professor/adjunct with Family Medicine; practitioner-educator

Tina Karonik

Host, family doctor and professor; contributes clinical perspective on guidelines and practice

Mike Colbert

Co-host; clinician/researcher; provides practical clinical insights

Reviews

4.6 out of 5 stars from 557 ratings

Library
I LOVE this podcast, it is the best as far as evidenced based medicine goes! It is succinct, clear and fair.
I just got on to re-listen to many of my favorite episodes and only 6 are available. What happened to your podcast library? Can I find them somewhere else?
Apple Podcasts
5
KiWa7
United States10 months ago
Reader’s Digest for Clinicians
Dr. McCormack is the reason I eagerly await next month’s episode 🙏🏻😇 also one of the best pharmacy professors out there!
Apple Podcasts
5
vKalTse8829
Canada2 years ago
Science?
I love the podcasts for the science but I have to object to the latest for treatment of so-called “cis” gender men. Cis-gender men are men. Please do not fall prey to ideologically driven language and stay science based. This is the Best Science Medicine Podcast after all.
Apple Podcasts
3
Mosquito-Girl
Canada2 years ago
Vitamin D
The only thing we ever have seen any evidence of value and THAT not definitive is in malabsorptive Bariatric Surgery. BUT why are you blathering when the preventive Tool was removed 20+ years ago with WH study and Estrogens. And PROVEN FALSE! (See Makary, BLIND SPOTS). Be real and honest or you are off my list.
Apple Podcasts
3
Dr. Buckskin
United States2 years ago
Consider opening it up
Hi, In the day and age of mis information and disinformation, would be nice to make all episodes more readily available and accessible. Important information being shared.
Apple Podcasts
4
hparwana
Canada3 years ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Audience emphasizes helpful guidance for shared decision making and prescribing.

Many appreciate the clear synthesis of trials and real-world relevance for clinicians.

Some critique occasional humor or pacing, but overall high regard for usefulness.

Listeners praise concise, evidence-based content that's practical and entertaining.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#69	Canada/Health & Fitness/Medicine
Apple Podcasts	#53	Belgium/Health & Fitness/Medicine
Apple Podcasts	#64	Sweden/Health & Fitness/Medicine
Apple Podcasts	#105	China/Health & Fitness/Medicine
Apple Podcasts	#107	South Africa/Health & Fitness/Medicine
Apple Podcasts	#185	Hong Kong/Health & Fitness/Medicine

Talking Points

Recent interactions between the hosts and their guests.

Episode 624: PCSK9 Inhibitors: Cardiovascular prevention panacea or pricey pokes?

Q: How should clinicians think about the new Vesalius CV primary-prevention-like data and its implications?

The study broadens the potential beneficiary pool by including high-risk individuals without prior events, but follow-up was longer and the population definition remains nuanced, so interpretation should be cautious and contextualized within overall cardiovascular risk management.

Episode 624: PCSK9 Inhibitors: Cardiovascular prevention panacea or pricey pokes?

Q: What was the actual clinical question they tried to answer about PCSK9 inhibitors?

Whether PCSK9 inhibitors like evolocumab and alirocumab are effective in preventing cardiovascular events, and how this varies between primary and secondary prevention contexts.

Episode 618: From Nerve Pain to Knee Pain: Gabapentinoids for osteoarthritis

Q: What did the four randomized trials show about gabapentinoids for osteoarthritis, and how strong is the evidence?

The trials suggest a tendency for gabapentinoids to outperform placebo on pain and function, but the evidence is limited by small sample sizes, varying blinding, and a lack of responder analyses, making the strength of the overall conclusion modest.

Episode 616: Taking the “ouch” out of IUD insertion: Can topical lidocaine help?

Q: What is the general approach to pain management during IUD inserions?

Typically, different analgesic options are discussed with patients, and there is no standard of practice for this.

Episode 616: Taking the “ouch” out of IUD insertion: Can topical lidocaine help?

Q: Can you let us know about the evidence?

Topical lidocaine, prilocaine cream reduces pain at both tenaculum placement and IUD insertion, while lidocaine spray also shows benefits but with some side effects.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
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Interests
Professions
Age Range
Household Income
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Frequently Asked Questions About Best Science Medicine Podcast

What is Best Science Medicine Podcast about and what kind of topics does it cover?

The show delivers concise, evidence-based medicine content focused on drug therapy, practical interpretation of trials, and real-world prescribing. Across episodes, hosts dissect major trials, compare treatment strategies, and translate complex data into actionable guidance for physicians, pharmacists, and other health professionals. A hallmark is balancing efficacy with safety, cost, and patient preference, often featuring clinician-experts who contextualize evidence for day-to-day care. The format blends rigorous review with accessible humor, aiming to empower listeners to apply the latest findings in shared decision-making and practice. Noteworthy is the consistent emphasis on practical applicability over theoretical debate, plus a recur... more

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Which podcasts are similar to Best Science Medicine Podcast?

These podcasts share a similar audience with Best Science Medicine Podcast:

1. AFP: American Family Physician Podcast
2. Frankly Speaking About Family Medicine
3. White Coat, Black Art
4. The Dose
5. The Curbsiders Internal Medicine Podcast

How many episodes of Best Science Medicine Podcast are there?

Best Science Medicine Podcast launched 18 years ago and published 20 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Best Science Medicine Podcast?

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What guests have appeared on Best Science Medicine Podcast?

Recent guests on Best Science Medicine Podcast include:

1. Danielle Perry
2. Tony Nickonchuk
3. Samantha Moe
4. Mike Kolber
5. Emily Mapplethorpe
6. Gavin Lowe
7. Émélie Braschi
8. Jessica Kirkwood

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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