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Artwork for Base to Base Biotech

Base to Base Biotech

Jim Cornall
Artificial Intelligence
Clinical Trials
George Medicines
Prostate Cancer
Parkinson's Disease
Kazia Therapeutics
Puretech Health
DIA
Bora Pharmaceuticals
Cell Therapy
Cell and Gene Therapy
Houdini Bio
Gene Therapy
Congenital Myotonic Dystrophy
Owkin
Revalesio
Ultrasound AI
Endometriosis
Vandria
Obesity

The Base to Base Biotech podcast is a weekly look at what's happening in the world of biotech, with interviews with biotech leaders around the world.

Whether it's a new drug, cutting-edge technology, product launches, new technology, major finding announcement or clinical trial results, Base to Base Biotech keeps you informed.

The podcast is hosted by former biotech editor and broadcaster, the awa... more

PublishesWeeklyEpisodes70Foundeda year ago
Number of ListenersCategories
Life SciencesHealth & FitnessScienceMedicine

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Artwork for Base to Base Biotech

Latest Episodes

This week, we have a conversation with Peter G. Milner, founder and director of Renexxion, about GI motility disorders.

Renexxion

Renexxion, Inc. is a privately held US-headquartered clinical-stage biopharmaceutical company, with a subsidiary in Ir... more

Times:

01:33 Cyllene Tx

21:37 LinusBio

This week, we have conversations with LinusBio founder and Mt. Sinai environmental professor, Dr. Manish Arora, as well as with Philippe Chambon, CEO of Cyllene Therapeutics (Cyllene Tx).

Cyllene Therapeutic... more

This week, we have a conversation with Kyle Cordova, founder and CEO of AquaPoro.

AquaPoro

AquaPoro is a deeptech company engineering systems that can harvest water from the atmosphere based in California that was spun out of Jordan's Royal Scienti... more

Times:

02:58 Deep Science Ventures

22:16 4basebio

This week, we have a conversation with Amy Walker, CEO of 4basebio, and Adam Tomassi-Russell, senior director, climate, at Deep Science Ventures.

4basebio

4basebio is a UK-based biotechnology com... more

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Recent Guests

Kyle Cordova
Founder and CEO of AquaPoro
AquaPoro
Episode: Base to Base biotech podcast 68: Water from air for pharma and beyond
Adam Tomassi-Russell
Senior Director, Climate at Deep Science Ventures
Deep Science Ventures
Episode: Base to Base biotech podcast 67: Synthetic DNA and crossing the blood-brain barrier
Amy Walker
CEO of 4basebio
4basebio
Episode: Base to Base biotech podcast 67: Synthetic DNA and crossing the blood-brain barrier
Jeff Fischer
President
Longhorn Vaccines & Diagnostics
Episode: Base to Base biotech podcast 66: The future of clinical trials and breakthroughs in molecular testing
Hannah Amies
CEO and Founder
Luvida
Episode: Base to Base biotech podcast 66: The future of clinical trials and breakthroughs in molecular testing
Jonathan Cohen-Gold
CEO and co-founder of Houdini Bio
Houdini Bio
Episode: Base to Base biotech podcast 65: Giving medicine a genetic camouflage
Jean-Baptiste Agnus
Chief Commercial Officer, Bora Pharmaceuticals
Bora Pharmaceuticals
Episode: Base to Base biotech podcast 64: Solving logistics challenges
Mark Sawicki
CEO of Cryoport Systems; Chief Scientific Officer of Cryoport, Inc.
Cryoport Systems / Cryoport, Inc.
Episode: Base to Base biotech podcast 63: Cell and gene therapy logistics, and turning back the Parkinson’s clock
Nick Manusos
CEO of Kenai Therapeutics
Kenai Therapeutics
Episode: Base to Base biotech podcast 63: Cell and gene therapy logistics, and turning back the Parkinson’s clock

Host

Jim Cornall
Host of Base to Base Biotech, a veteran biotech broadcaster and editor, guiding conversations with industry leaders.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Base to Base biotech podcast 20: Terumo BCT boosts CAR-T cell manufacturing, and Orbis on macrocycles
Q: What are macro cycles and how do they help with treatments?
Morten Graugaard describes macrocycles as cyclic peptide structures that can be made orally available with a broader chemical diversity using fully synthetic building blocks, enabling drug-like properties and potential oral therapies in areas traditionally dominated by injectable biologics; Orbis uses AI-assisted design and high-throughput synthesis to rapidly identify and optimize these compounds.
Base to Base biotech podcast 20: Terumo BCT boosts CAR-T cell manufacturing, and Orbis on macrocycles
Q: Anything that can boost CAR-T cell production?
The guest explains that Terumo BCT's integrated Quantum system streamlines seven manufacturing steps into four, enabling higher transduction efficiency, faster production timelines, and reduced reliance on viral vectors, all contributing to lower costs and broader patient access.
Base to Base biotech podcast 25: Molecular glue degradation
Q: Yeah, you mentioned AI earlier. How has that assisted in the process, and how does it continue to be employed in the company?
AI is integrated across the platform to identify hot targets, predict protein surfaces, optimize small-molecule warping to induce the right PPIs, and accelerate target discovery through large-scale data analyses from PubMed to clinical trial data.
Base to Base biotech podcast 25: Molecular glue degradation
Q: But not the band.
We name our meeting rooms after bands and use Queen as the discovery platform; it organizes the workflow from target entry through screening and lead generation, with a culture around science and collaboration.
Base to Base biotech podcast 25: Molecular glue degradation
Q: Next, then, could you tell me a little bit about the Queen?
Queen is our discovery engine, an umbrella concept that combines data, proteomics, virtual screening, and screening assays to generate first hits and leads, followed by lead optimization and consideration of CMC and DMPK for patient populations.

Audience Metrics

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Frequently Asked Questions About Base to Base Biotech

What is Base to Base Biotech about and what kind of topics does it cover?

This show consistently covers cutting-edge biotech and pharmaceutical development from discovery to delivery, with a heavy emphasis on practical challenges, partnerships, and real-world impact. Recent discussions spotlight gene therapy and DNA design to improve durability and cost, CDMO networks and AI-enabled manufacturing, logistics for cell and gene therapies, novel stroke and cancer therapies, targeted drug delivery, organ transplantation, and patient advocacy influences on trial design and access. A standout pattern is the blend of science deep-dives with business strategy—entrepreneurship, funding models, regulatory pathways, and partnerships—providing listeners with actionable context for investors, operators, and researchers seeking... more

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Which podcasts are similar to Base to Base Biotech?

These podcasts share a similar audience with Base to Base Biotech:

1. Invest Like the Best with Patrick O'Shaughnessy
2. The Daily
3. Worklife with Molly Graham

How many episodes of Base to Base Biotech are there?

Base to Base Biotech launched a year ago and published 70 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Base to Base Biotech?

Recent guests on Base to Base Biotech include:

1. Kyle Cordova
2. Adam Tomassi-Russell
3. Amy Walker
4. Jeff Fischer
5. Hannah Amies
6. Jonathan Cohen-Gold
7. Jean-Baptiste Agnus
8. Mark Sawicki

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