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Gene Therapy
Clinical Trials
Cell Therapy
Gene Editing
Adeno-Associated Virus
CRISPR
Gene and Cell Therapy
Cell and Gene Therapy
Rare Diseases
Biotechnology
Gene & Cell Therapy
Crispr-Cas9
Regulatory Landscape
Cas9-Clipt
ASGCT Annual Meeting
T-Cells
FDA
Orphan Drug
Policy Summit
Molecular Therapy

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

PublishesTwice monthlyEpisodes76Founded4 years ago
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ChemistryLife SciencesScience

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Artwork for ASGCT Podcast Network

Latest Episodes

In this episode, host Emily Walsh Martin revisits her 2022 Caregiver’s Perspective interview with Amber Freed, founder of SLC6A1 Connect. Amber is a caregiver to her son Maxwell, who has since received treatment for SLC6A1. Emily and Amber discuss Ma... more

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Emily Walsh Martin, PhD, spoke with Amber Freed, founder and CEO of SLC6A1 Connect, a patient organization focused on accelerating the development of therapies for SLC6A1 patients like her son Maxwell.

Show your support for ASGCT!: asgct.org... more

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In this episode, Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso and Dr. Rita Perlingeiro (University of Minnesota) will discuss an article recently published in Molecular Therapy titled, “Preclinical quality, safety, and efficacy of a CGMP iPS... more

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In this episode of The Issue, Emily Walsh Martin is joined by Dr. Ralph Brandenberger, Master Principal; Head of CMC at Dark Horse Consulting for a discussion on due diligence – the most important time in a company’s existence, be it for funding, par... more

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Recent Guests

Amber Freed
Founder and CEO of SLC6A1 Connect, a patient organization for SLC6A1-related epilepsy
SLC6A1 Connect
Episode: Key Considerations of Gene Therapy Development: A Caregiver's Story
Dr. Joseph Glorioso
Editor-in-Chief of Molecular Therapy
Molecular Therapy
Episode: CGMP iPSC-derived myogenic progenitor product for the treatment of muscular dystrophies with Joseph Glorioso and Rita Perlingeiro
Dr. Rita Perlingeiro
University of Minnesota researcher
University of Minnesota
Episode: CGMP iPSC-derived myogenic progenitor product for the treatment of muscular dystrophies with Joseph Glorioso and Rita Perlingeiro
Dr. Ralph Brandenberger
Master Principal Head of CMC
Dark Horse Consulting
Episode: The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Norman Drzeniek
Physician scientist, Department of Rheumatology and Immunology, Charité Medical University; Berlin Institute of Health
Charité / BIH
Episode: mRNA-based CAR T cell engineering with Norman Drzeniek and Niklas Kotzian
Niklas Kotzian
Co-author on the study; biochemistry student (intern)
Charité / BIH
Episode: mRNA-based CAR T cell engineering with Norman Drzeniek and Niklas Kotzian
Melissa Majerol
Model lead for the Cell and Gene Therapy Access Model at the Center for Medicare and Medicaid Innovation
Centers for Medicare and Medicaid Services
Episode: The Issue - Evolving Patient Access to CGTs via Innovation in Medicaid Reimbursement Models with Melissa Majerol
Krish Saha
Professor of Biomedical Engineering, Pediatrics, and Bioethics at the University of Wisconsin-Madison, specialized in ex vivo cell therapy.
University of Wisconsin-Madison
Episode: Cas9-CLIPT-mediated integration of large transgenes with Krishanu Saha, Anna Tommasi, and Dan Cappabianca
Anna Tommasi
Graduate student in the UW Biomedical Engineering Program and a member of the Saha Lab.
University of Wisconsin-Madison
Episode: Cas9-CLIPT-mediated integration of large transgenes with Krishanu Saha, Anna Tommasi, and Dan Cappabianca

Hosts

Marcin Kortylewski
Host of Molecular Therapy Podcast
Emily Walsh-Martin
Host of the issue
Daniel Stone
Associate Editor-in-Chief of the ASGCT Journal Molecular Therapy Advances
Dr. Rory Bricker-Anthony
Scientific Editor of the Molecular Therapy Family of Journals
Lynnea Olivarez
Chair of the Communications Committee

Reviews

4.9 out of 5 stars from 25 ratings
  • Waiting for next episodes…

    Finally a podcast for Gene therapy!! Great job.

    Looking forward to upcoming episodes to learn more about this amazing field.

    Apple Podcasts
    5
    Prasad Trivedi
    United States3 years ago

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Finally a podcast for Gene therapy!! Great job. Looking forward to upcoming episodes to learn more about this amazing field.
Waiting for next episodes...

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Talking Points

Recent interactions between the hosts and their guests.

The Issue – A Caregiver’s Journey from Development to Treatment with Amber Freed, Founder of SLC6A1 Connect
Q: How did you weigh the unknowns when deciding to pursue treatment for Maxwell?
I compared the lack of options in rare diseases to a cancer patient's scenario where there is a standard of care, and concluded that despite no guarantees, the potential for meaningful impact justified pursuing a path forward, particularly given the severe uncertainties and the urgency of Maxwell's needs.
Key Considerations of Gene Therapy Development: A Caregiver's Story
Q: What has the experience taught you about the industry's communication of risks and timelines to caregivers?
She argues that while efficacy is often discussed, timelines are frequently misrepresented, causing false hope; she stresses the need for realistic timelines and better education through patient organizations.
Key Considerations of Gene Therapy Development: A Caregiver's Story
Q: Could you share Maxwell's journey and how it shaped your approach to exploring gene therapy options?
Amber outlines Maxwell's early developmental concerns, definitive diagnosis of SLC6A1, and the decision to engage in gene therapy research, motivated by a belief that parents can drive progress and connect with researchers to pursue potential cures.
The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: What outcomes make a diligence successful beyond a potential deal?
A successful diligence provides a clear, actionable roadmap or IDP that outlines what must be done, highlights risks, and positions the asset for rapid progress post-diligence, regardless of whether funding occurs.
The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: How can a sponsor prepare a data room to survive deep scrutiny?
Prioritize a structured document triage, pre-identify critical questions, use a transparent narrative to explain data gaps, and ensure there is context for any complex results through proactive conversations before sharing data.

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Frequently Asked Questions About ASGCT Podcast Network

What is ASGCT Podcast Network about and what kind of topics does it cover?

The show centers on gene and cell therapy with guest experts ranging from academic researchers to biotech leaders and policy makers. Episodes frequently explore innovative delivery methods, genome editing, RNA-based approaches, in vivo and ex vivo therapies, manufacturing challenges, and patient access models. A standout pattern is cross-disciplinary collaboration—academia, industry, and regulatory perspectives converge to illuminate both technical advances and real-world implications for patients. Listeners can expect topical deep dives into cutting-edge therapies, practical manufacturing insights, and discussions about accessibility and ethical considerations in gene therapy.

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Which podcasts are similar to ASGCT Podcast Network?

These podcasts share a similar audience with ASGCT Podcast Network:

1. BioCentury This Week
2. Biotech Hangout
3. Cell & Gene: The Podcast
4. The Long Run with Luke Timmerman
5. The Readout Loud

How many episodes of ASGCT Podcast Network are there?

ASGCT Podcast Network launched 4 years ago and published 76 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on ASGCT Podcast Network?

Recent guests on ASGCT Podcast Network include:

1. Amber Freed
2. Dr. Joseph Glorioso
3. Dr. Rita Perlingeiro
4. Dr. Ralph Brandenberger
5. Norman Drzeniek
6. Niklas Kotzian
7. Melissa Majerol
8. Krish Saha

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