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Gene Therapy
Clinical Trials
Cell Therapy
Gene Editing
CRISPR
Cell and Gene Therapy
Adeno-Associated Virus
Rare Diseases
Gene and Cell Therapy
Biotechnology
Crispr-Cas9
Gene & Cell Therapy
Regulatory Landscape
ASGCT
Cas9-Clipt
Sickle Cell Disease
ASGCT Annual Meeting
FDA
T-Cells
Patient Advocacy

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

PublishesDailyEpisodes100Founded4 years ago
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Life SciencesChemistryScience

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Artwork for ASGCT Podcast Network

Latest Episodes

Molecular Therapy Oncology has released a new special collection, Advancements in Pediatric Cancer Therapy. Listen in as guest editor Nirali Shah and Editor-in-Chief Timothy Cripe discuss articles in this special collection, which covers the history,... more

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In this episode of The Issue, Sara Johnson Davis, Senior Director of Government Affairs at Ardelyx and former Vice President, Head of Patient Advocacy & Policy at Fulcrum Therapeutics, joins host Sanjay D’Souza, PhD, to discuss the essential role of ... more

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Recorded live at the ASGCT 2026 Annual Meeting in Boston, Le Cong, PhD joins hosts Jason West, PhD and Sanjay D’Souza, PhD for a discussion on his work in genome engineering and the early development of CRISPR/Cas9. The three then dive into Dr. Cong’... more

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This episode focuses on Molecular Therapy’s upcoming special issue, the biological clock of aging and the possibility of lifespan extension. Listen in as Dr. Joseph Glorioso, Editor-in-Chief of Molecular Therapy, discusses the molecular mechanisms th... more

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Recent Guests

Nirali Shah
Guest editor of the special pediatric cancer immunotherapy collection
Special collection editor for Molecular Therapy Oncology
Episode: Advancements in Pediatric Cancer Therapy with Nirali Shah and Timothy Cripe
Sara Johnson Davis
Recognized leader in patient advocacy and public affairs
Prispa Therapeutics (former), Fulcrum (discussion reference)
Episode: From Innovation to Access: Patient Advocacy as a Strategic Partner with Sara Johnson Davis
Le Cong
PhD, Stanford researcher focusing on AI-driven genome engineering and SSAP-based large gene insertion
Stanford University
Episode: Using AI to Drive Innovation in CGT with Le Cong, PhD
Christin Glorioso
Neuroscientist and physician; guest editor
NeuroAge Therapeutics
Episode: The biological clock of aging and the possibility of lifespan extension with Christin Glorioso and John Bell
John Bell
Researcher from University of Ottawa; guest
University of Ottawa
Episode: The biological clock of aging and the possibility of lifespan extension with Christin Glorioso and John Bell
Anna Maurer
Assistant Professor of Biophysics, University of Michigan; AAV biology researcher
University of Michigan
Episode: Against the Odds: How Dr. Anna Maurer Built a Life in Science
Fyodor Urnov
Leading figure in genome editing and in vivo therapies
UC Berkeley / Innovative Genomics Institute
Episode: A Discussion on the Past, Present, and Future Promise of Gene Editing with Fyodor Urnov, PhD
Dr. Jennifer Adair
Guest editor of the Molecular Therapy Advances special issue on rare diseases
Episode: How rare diseases are shaping therapeutic innovation with Jennifer Adair, Claire Booth, Terry Flotte and Donald Kohn
Dr. Claire Booth
Guest editor contributing to the special issue and discussions on regulatory and manufacturing aspects
Episode: How rare diseases are shaping therapeutic innovation with Jennifer Adair, Claire Booth, Terry Flotte and Donald Kohn

Reviews

4.9 out of 5 stars from 25 ratings
  • Waiting for next episodes…

    Finally a podcast for Gene therapy!! Great job.

    Looking forward to upcoming episodes to learn more about this amazing field.

    Apple Podcasts
    5
    Prasad Trivedi
    United States4 years ago

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Waiting for next episodes...
Finally a podcast for Gene therapy!! Great job. Looking forward to upcoming episodes to learn more about this amazing field.

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Talking Points

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From Innovation to Access: Patient Advocacy as a Strategic Partner with Sara Johnson Davis
Q: How has the shift from theoretical to approved therapies changed conversations with patient communities?
The discussion has become more tangible as patients ask what the therapy means for them, including eligibility, access, and long-term risks, while still addressing durability, safety, and burden.
From Innovation to Access: Patient Advocacy as a Strategic Partner with Sara Johnson Davis
Q: What is your advice for scientists and biotech leaders about engaging with patients early in the development process?
Engage with patients earlier than clinicians might expect; involve them in trial design, endpoints, and burden considerations so the drugs developed truly address patient needs, and avoid waiting until a recruitment issue arises.
Using AI to Drive Innovation in CGT with Le Cong, PhD
Q: What is the long-term vision for AI in the lab, and how might it scale research to impact patients?
The long-term vision includes AI-enabled co-scientists that can guide digital and physical experimentation at scale, accelerating discovery while maintaining safety through proper data production, regulatory alignment, and translational collaboration with clinicians to deliver real-world therapies.
Using AI to Drive Innovation in CGT with Le Cong, PhD
Q: How is AI being used to design guides and experiments, and what are the main benefits and caveats?
AI tools like Cas12 guide RNA ranking and CRISPR-GPT help accelerate design, reduce initial screening, and train new researchers; however, AI can hallucinate or introduce biases, so human validation remains essential and data quality is critical for reliable performance.
Using AI to Drive Innovation in CGT with Le Cong, PhD
Q: Can you explain the SSAP-based large gene insertion approach and how it differs from traditional genome editing?
SSAP uses a dead Cas9 as a GPS to deliver a phage-derived recombination protein to a programmable genome site, enabling insertion of donor DNA without the need for cutting the genome, potentially offering a safer and more versatile route for gene restoration.

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Frequently Asked Questions About ASGCT Podcast Network

What is ASGCT Podcast Network about and what kind of topics does it cover?

This network spotlights cell and gene therapy professionals, researchers, clinicians, and advocacy voices, with a strong focus on translational science, delivery platforms, regulatory evolution, and patient access. Conversations span aging biology, rare diseases, genome editing, CNS-directed gene therapy, vector design, manufacturing hurdles, and policy, often pairing scientific deep-dives with practical implications for developers, providers, and funders. A standout trait is the mix of highly technical discussions and founder/advocacy perspective, making it useful for listeners evaluating partnerships, sponsorships, and opportunities to connect with a deeply engaged community working at the cutting edge of life sciences and biotech policy.... more

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Which podcasts are similar to ASGCT Podcast Network?

These podcasts share a similar audience with ASGCT Podcast Network:

1. Cell & Gene: The Podcast
2. The Long Run with Luke Timmerman
3. BioCentury This Week
4. The Readout Loud
5. Nature Podcast

How many episodes of ASGCT Podcast Network are there?

ASGCT Podcast Network launched 4 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on ASGCT Podcast Network?

Recent guests on ASGCT Podcast Network include:

1. Nirali Shah
2. Sara Johnson Davis
3. Le Cong
4. Christin Glorioso
5. John Bell
6. Anna Maurer
7. Fyodor Urnov
8. Dr. Jennifer Adair

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