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Gene Therapy
Gene & Cell Therapy
Regulatory Landscape
Clinical Trials
Orphan Drug
Cell and Gene Therapy
ASGCT Annual Meeting
Rare Diseases
FDA CBER
Cystic Fibrosis
Covid-19
Immunogenicity
CRISPR
Biologics License Application (BLA)
Cell Therapy
Aptamer Technology
AAV Gene Therapy
Gene Therapy Development
Adeno-Associated Virus
Innovative Trial Designs

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

PublishesTwice monthlyEpisodes74Founded3 years ago
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Artwork for ASGCT Podcast Network

Latest Episodes

In this episode, Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso and Dr. Rita Perlingeiro (University of Minnesota) will discuss an article recently published in Molecular Therapy titled, “Preclinical quality, safety, and efficacy of a CGMP iPS... more

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In this episode of The Issue, Emily Walsh Martin is joined by Dr. Ralph Brandenberger, Master Principal; Head of CMC at Dark Horse Consulting for a discussion on due diligence – the most important time in a company’s existence, be it for funding, par... more

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Dr. Marcin Kortylewski (Oligonucleotide therapies and applications Section Editor of Molecular Therapy Nucleic Acids) sits down with Dr. Norman Michael Drzeniek and Niklas Kotzian from the Berlin Institute of Health at Charité. Join them as they disc... more

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In this episode, Melissa Majerol, Model Lead of the Cell and Gene Therapy Access Model at the Center for Medicare and Medicaid Innovation (CMMI) at CMS, breaks down how the CMMI Access Model program aims to simplify and accelerate patient access to i... more

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Recent Guests

Dr. Ralph Brandenberger
Master Principal Head of CMC
Dark Horse Consulting
Episode: The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Norman Drzeniek
Physician scientist, Department of Rheumatology and Immunology, Charité Medical University; Berlin Institute of Health
Charité / BIH
Episode: mRNA-based CAR T cell engineering with Norman Drzeniek and Niklas Kotzian
Niklas Kotzian
Co-author on the study; biochemistry student (intern)
Charité / BIH
Episode: mRNA-based CAR T cell engineering with Norman Drzeniek and Niklas Kotzian
Melissa Majerol
Model lead for the Cell and Gene Therapy Access Model at the Center for Medicare and Medicaid Innovation
Centers for Medicare and Medicaid Services
Episode: The Issue - Evolving Patient Access to CGTs via Innovation in Medicaid Reimbursement Models with Melissa Majerol
Krish Saha
Professor of Biomedical Engineering, Pediatrics, and Bioethics at the University of Wisconsin-Madison, specialized in ex vivo cell therapy.
University of Wisconsin-Madison
Episode: Cas9-CLIPT-mediated integration of large transgenes with Krishanu Saha, Anna Tommasi, and Dan Cappabianca
Anna Tommasi
Graduate student in the UW Biomedical Engineering Program and a member of the Saha Lab.
University of Wisconsin-Madison
Episode: Cas9-CLIPT-mediated integration of large transgenes with Krishanu Saha, Anna Tommasi, and Dan Cappabianca
Dan Cappabianca
Former Saha Lab member and current postdoc in the SOGI Lab at the University of Wisconsin-Madison.
University of Wisconsin-Madison
Episode: Cas9-CLIPT-mediated integration of large transgenes with Krishanu Saha, Anna Tommasi, and Dan Cappabianca
Niki Paulk
CEO and founder of Siren Biotechnology
Siren Biotechnology
Episode: The Issue - Entrepreneurship, Fundraising, and the Future of Cell & Gene Therapy with Dr. Niki Paulk
Jim Burns
CEO of Ensoma
Ensoma
Episode: The Issue - Unlocking New Therapeutic Potential: Ensoma’s Platform for Rare Disease and Oncology

Hosts

Marcin Kortylewski
Host of Molecular Therapy Podcast
Emily Walsh-Martin
Host of the issue
Daniel Stone
Associate Editor-in-Chief of the ASGCT Journal Molecular Therapy Advances
Dr. Rory Bricker-Anthony
Scientific Editor of the Molecular Therapy Family of Journals
Lynnea Olivarez
Chair of the Communications Committee

Reviews

4.9 out of 5 stars from 25 ratings
  • Waiting for next episodes…

    Finally a podcast for Gene therapy!! Great job.

    Looking forward to upcoming episodes to learn more about this amazing field.

    Apple Podcasts
    5
    Prasad Trivedi
    United States3 years ago

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Finally a podcast for Gene therapy!! Great job. Looking forward to upcoming episodes to learn more about this amazing field.
Waiting for next episodes...

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The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: What outcomes make a diligence successful beyond a potential deal?
A successful diligence provides a clear, actionable roadmap or IDP that outlines what must be done, highlights risks, and positions the asset for rapid progress post-diligence, regardless of whether funding occurs.
The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: How can a sponsor prepare a data room to survive deep scrutiny?
Prioritize a structured document triage, pre-identify critical questions, use a transparent narrative to explain data gaps, and ensure there is context for any complex results through proactive conversations before sharing data.
The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: What are the key factors you look at first when entering a diligence room?
First, assess the team's depth and experience, then the quality and clarity of data, and finally how well the documentation supports potential risks and development trajectories.
The Issue – Prepared under pressure: Navigating the due diligence process with Dr. Ralph Brandenberger
Q: Why is due diligence such a pivotal moment for a cell and gene therapy program?
Because it sets the tone for partnerships or investments and often determines how a program will be positioned going forward, including acceptance of risks and the design of future development plans.
The Issue - Evolving Patient Access to CGTs via Innovation in Medicaid Reimbursement Models with Melissa Majerol
Q: What makes sickle cell disease a good condition to focus on for this model?
Sickle cell disease is the most common rare disease in the U.S. and affects different states unequally, with some states anticipating a significant Medicaid impact due to high costs associated with new therapies.

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Frequently Asked Questions About ASGCT Podcast Network

What is ASGCT Podcast Network about and what kind of topics does it cover?

The show centers on gene and cell therapy with guest experts ranging from academic researchers to biotech leaders and policy makers. Episodes frequently explore innovative delivery methods, genome editing, RNA-based approaches, in vivo and ex vivo therapies, manufacturing challenges, and patient access models. A standout pattern is cross-disciplinary collaboration—academia, industry, and regulatory perspectives converge to illuminate both technical advances and real-world implications for patients. Listeners can expect topical deep dives into cutting-edge therapies, practical manufacturing insights, and discussions about accessibility and ethical considerations in gene therapy.

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Which podcasts are similar to ASGCT Podcast Network?

These podcasts share a similar audience with ASGCT Podcast Network:

1. Cell & Gene: The Podcast
2. Short Wave
3. The Readout Loud
4. This American Life
5. Throughline

How many episodes of ASGCT Podcast Network are there?

ASGCT Podcast Network launched 3 years ago and published 74 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on ASGCT Podcast Network?

Recent guests on ASGCT Podcast Network include:

1. Dr. Ralph Brandenberger
2. Norman Drzeniek
3. Niklas Kotzian
4. Melissa Majerol
5. Krish Saha
6. Anna Tommasi
7. Dan Cappabianca
8. Niki Paulk

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