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Gene Therapy
Gene & Cell Therapy
Regulatory Landscape
Clinical Trials
Orphan Drug
Rare Diseases
Cell and Gene Therapy
ASGCT Annual Meeting
FDA CBER
Cystic Fibrosis
Covid-19
Immunogenicity
Biologics License Application (BLA)
Cell Therapy
CRISPR
Aptamer Technology
AAV Gene Therapy
Gene Therapy Development
Adeno-Associated Virus
Innovative Trial Designs

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

PublishesTwice monthlyEpisodes69Founded3 years ago
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Life SciencesScienceChemistry

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Artwork for ASGCT Podcast Network

Latest Episodes

Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso joins researchers Kathy Steece-Collier (Michigan State University), Jeffrey Kordower (Arizona State University), and Fredric Manfredsson (Barrow Neurological Institute) to discuss their groundbrea... more

Host Dr. Emily Walsh Martin welcomes Dr. Niki Paulk, CEO and Founder of Siren Biotechnology, for a timely conversation on turning scientific promise into commercial success. Dr. Paulk offers perceptive insights into the complex world of biotech entre... more

YouTube

Host Emily Walsh Martin welcomes Dr. Jim Burns, CEO of Ensoma, to discuss the company's novel technological approach to treating both rare diseases and solid tumor oncology. Dr. Burns provides a detailed overview of Ensoma's platform and its applicat... more

YouTube

Join all four Editors-in-Chief of the Molecular Therapy family of journals for a special 2025 Retrospective. Editors Dr. Glorioso, Dr. Giangrande, Dr. Abou-el-Enein, and Dr. Cripe dive into the most exciting advancements in gene and cell therapy from... more

YouTube

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Recent Guests

Jim Burns
CEO of Ensoma
Ensoma
Episode: The Issue - Unlocking New Therapeutic Potential: Ensoma’s Platform for Rare Disease and Oncology
Dr. Kyriacos Mitrophanous
Chief Innovation Officer at OXB, experienced with lentiviral vectors development for over 25 years
Oxford Biomedica
Episode: Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Dr. Rachael Nimmo
Formerly Director for the Cell Technology Group at OXB, co-inventor of an innovative CAR T cell technology
Oxford Biomedica
Episode: Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Kimberly Haugstad
CEO of RareRising and a longtime rare disease advocate
RareRising
Episode: Patients Are the Center with Kimberly Haugstad, MBA
Dr. Rayne Rouce
Pediatric oncologist and physician scientist at Texas Children's Hospital
Texas Children's Hospital
Episode: 25 Years of Molecular Therapy with Drs. Rayne Rouce and Joe Glorioso
Dr. Stephen Kaminsky
Professor of Research in Genetic Medicine at Weill Cornell Medical College and Lead Author on a Phase 1 Clinical Trial of a New Vaccine for Cocaine Addiction
Weill Cornell Medical College
Episode: A Vaccine for Cocaine Addiction with Dr. Stephen Kaminsky
Dr. P.J. Brooks
Deputy Director of the Division of Rare Diseases Research Innovation at the National Center for Advancing Translational Sciences
NIH
Episode: Developing Therapeutic Platforms with Dr. P.J. Brooks
Dr. Kiran Musunuru
The Barry J. Gertz Professor for Translational Research at the University of Pennsylvania's Perelman School of Medicine
University of Pennsylvania, Children's Hospital of Philadelphia
Episode: The Ups and Downs of Conducting Groundbreaking Research with Dr. Kiran Musunuru
Dolan Sondhi
PhD Chemist and Assistant Professor at Weill Cornell Medical College
Weill Cornell Medical College
Episode: The Importance of Long-term Data with Dolan Sondhi, PhD - The Issue

Hosts

Dr. Rory Bricker-Anthony
Scientific Editor of the Molecular Therapy Family of Journals
Lynnea Olivarez
Chair of the Communications Committee

Reviews

4.9 out of 5 stars from 25 ratings
  • Waiting for next episodes…

    Finally a podcast for Gene therapy!! Great job.

    Looking forward to upcoming episodes to learn more about this amazing field.

    Apple Podcasts
    5
    Prasad Trivedi
    United States3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners praise the quality of content, noting it as a vital resource for learning about gene therapy.
Feedback highlights the engaging discussions with industry experts.
The podcast is recognized for shedding light on complex scientific topics in an accessible way.

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Talking Points

Recent interactions between the hosts and their guests.

Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Q: How do you see the best way to deliver an in vivo targeting vector?
We envision IV administration into the bloodstream since the vector is specifically targeted to T cells, allowing direct transduction.
Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Q: Do you have to arm these CAR T, say, with IL-18 or what are your thoughts about that?
We have not yet determined if additional armoring for the CAR T cells will be necessary; the initial clinical data is still being evaluated.
Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Q: Do you think that this strategy will be useful for treating autoimmune diseases?
Yes, there is potential for in vivo CAR T therapy to treat autoimmune diseases; initial trials have shown promising results in eradicating autoreactive B cells.
Generating CAR T cells in vivo with lentiviral vectors with Drs. Rachael Nimmo and Kyriacos Mitrophanous
Q: How do you avoid off-target transduction, like in the liver, for example?
The NIPA targeting approach helps avoid off-target transduction effectively, ensuring specific targeting to the T cells and minimizing unwanted effects.
A Molecular Glue Degrader to Control CRISPR with Drs. Krishanu Saha and Namita Khajanchi
Q: What do you believe are the prospects for adapting this technology?
We see this as a proof of concept study but believe it can be applied to many different types of diseases and indications, especially with effective delivery.

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Frequently Asked Questions About ASGCT Podcast Network

What is ASGCT Podcast Network about and what kind of topics does it cover?

This podcast explores the forefront of gene and cell therapy by featuring insightful discussions with experts in the field. Episodes highlight innovative research, technological advancements, and personal stories from leading scientists, professionals, and advocates focused on various aspects of gene therapy, including challenges, successes, and future potentials. Noteworthy topics include the evolution of therapeutic approaches, patient advocacy, and the importance of community engagement in advancing treatment options for rare diseases.

The unique perspective offered through expert interviews and retrospective analyses makes the content especially appealing to professionals and enthusiasts interested in the sciences, particularly those f... more

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1. Cell & Gene: The Podcast
2. The Readout Loud
3. Science Magazine Podcast
4. Nature Podcast
5. Prof G Markets

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ASGCT Podcast Network launched 3 years ago and published 69 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on ASGCT Podcast Network?

Recent guests on ASGCT Podcast Network include:

1. Jim Burns
2. Dr. Kyriacos Mitrophanous
3. Dr. Rachael Nimmo
4. Kimberly Haugstad
5. Dr. Rayne Rouce
6. Dr. Stephen Kaminsky
7. Dr. P.J. Brooks
8. Dr. Kiran Musunuru

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