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Gene Therapy
Clinical Trials
Cell Therapy
Gene Editing
CRISPR
Cell and Gene Therapy
Adeno-Associated Virus
Rare Diseases
Gene and Cell Therapy
Biotechnology
Crispr-Cas9
Gene & Cell Therapy
Regulatory Landscape
ASGCT
Cas9-Clipt
Sickle Cell Disease
ASGCT Annual Meeting
Lentiviral Vectors
FDA
T-Cells

The American Society of Gene & Cell Therapy is the premier membership organization for professionals working in cell and gene therapy. On this network, we're sharing exciting stories from our members and the greater scientific community.

PublishesDailyEpisodes100Founded4 years ago
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Latest Episodes

We are excited to announce that Dr. Paloma Giangrande has committed to a second term as Editor-in-Chief of Molecular Therapy Nucleic Acids (MTNA). In this episode, Dr. Marcin Kortylewski, the Oligonucleotides: Therapies and Applications section edito... more

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In this episode of Scientists, Unedited, Luigi Naldini, PhD, Professor of Cell and Tissue Biology and of Gene and Cell Therapy at the San Raffaele University School of Medicine and Scientific Director of the San Raffaele Telethon Institute for Gene T... more

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In this episode of The Issue, CEO of Life Biosciences Jerry McLaughlin joins hosts Sanjay D’Souza, PhD and Jason West, PhD for a discussion on how epigenetic reprogramming could restore function in aging and injured cells. He explains the science beh... more

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This episode, hosted by Daniel Stone, Associate Editor-in-Chief of Molecular Therapy Advances, focuses on the article, Normothermic perfusion of human livers for profiling lentiviral vector pharmacokinetics and transduction. Listen as Robert Carlisle... more

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Recent Guests

Paloma Giangrande
Editor-in-Chief of Molecular Therapy Nucleic Acids with experience in academia, biotechnology, and scientific publishing
Molecular Therapy Nucleic Acids
Episode: The Future of Molecular Therapy Nucleic Acids
Luigi Naldini
Professor of cell and tissue biology and gene and cell therapy, and scientific director of a gene therapy institute
San Raffaele Telethon Institute for Gene Therapy
Episode: The Long Road from Bench to Clinic: A Conversation with Dr. Luigi Naldini on Science, Family, and the Courage to Build Something New
Jerry McLaughlin
CEO of Life Biosciences with a career in pharmaceutical and biotechnology companies
Life Biosciences
Episode: From Aging Cells to Optic Neuropathy with Jerry McLaughlin
Brannon Nicholls
First author of the paper; DPhil student in Advanced Biosciences and Viral Products Program
University of Oxford
Episode: An Ex Vivo Human Liver Model for Lentiviral Vector Profiling
Robert Carlisle
Professor in Biomedical Engineering; Director of MS in Nanotechnology for Medicine and Health Care
University of Oxford
Episode: An Ex Vivo Human Liver Model for Lentiviral Vector Profiling
Bruce Levine
Professor in Cancer Gene Therapy, University of Pennsylvania
University of Pennsylvania
Episode: From Aspiring Astronaut to CAR-T Pioneer: A Journey of Serendipity with Bruce Levine, PhD
Nirali Shah
Guest editor of the special pediatric cancer immunotherapy collection
Special collection editor for Molecular Therapy Oncology
Episode: Advancements in Pediatric Cancer Therapy with Nirali Shah and Timothy Cripe
Sara Johnson Davis
Recognized leader in patient advocacy and public affairs
Prispa Therapeutics (former), Fulcrum (discussion reference)
Episode: From Innovation to Access: Patient Advocacy as a Strategic Partner with Sara Johnson Davis
Le Cong
PhD, Stanford researcher focusing on AI-driven genome engineering and SSAP-based large gene insertion
Stanford University
Episode: Using AI to Drive Innovation in CGT with Le Cong, PhD

Reviews

4.9 out of 5 stars from 25 ratings
  • Waiting for next episodes…

    Finally a podcast for Gene therapy!! Great job.

    Looking forward to upcoming episodes to learn more about this amazing field.

    Apple Podcasts
    5
    Prasad Trivedi
    United States4 years ago

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Waiting for next episodes...
Finally a podcast for Gene therapy!! Great job. Looking forward to upcoming episodes to learn more about this amazing field.

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Talking Points

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The Long Road from Bench to Clinic: A Conversation with Dr. Luigi Naldini on Science, Family, and the Courage to Build Something New
Q: How do you envision the future of gene therapy?
Naldini sees a need to keep effective treatments accessible while improving affordability and delivery. He describes research into genome editing, targeted gene insertion, less intensive conditioning, and in vivo treatment delivery.
The Long Road from Bench to Clinic: A Conversation with Dr. Luigi Naldini on Science, Family, and the Courage to Build Something New
Q: When did you start thinking that gene therapy could actually become a clinical reality?
After the team demonstrated gene transfer into neurons in vivo, Naldini saw the technology as more promising. A company later offered to license it and develop it toward clinical testing.
The Future of Molecular Therapy Nucleic Acids
Q: Do you have any advice to especially young researchers submitting to our journal how to use AI tools when preparing the manuscript for publishing?
She recommends using AI as an assistant for computational work and improving text clarity, not to replace original thinking or create scientific content. Authors should disclose how they used AI, independently verify outputs, and ensure data and methods remain transparent and traceable.
The Future of Molecular Therapy Nucleic Acids
Q: What drew you first to science and RNA biology or RNA therapeutics?
Giangrande says curiosity about nature and the human body led her to science. RNA aptamers introduced during her postdoctoral work sparked her interest in RNA biology, and she saw RNA interference as a promising drug technology whose major challenge was delivery.
From Aging Cells to Optic Neuropathy with Jerry McLaughlin
Q: What have you done to convince yourselves that the risk-benefit profile was suitable for testing in humans?
He describes extensive mouse and nonhuman-primate safety studies, reporting no tumors, evidence of pluripotency, or significant adverse events in the studies discussed. The company also completed IND-enabling work, including assessments of biodistribution and longer-term safety, before beginning its Phase 1 trial.

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Frequently Asked Questions About ASGCT Podcast Network

What is ASGCT Podcast Network about and what kind of topics does it cover?

This network spotlights cell and gene therapy professionals, researchers, clinicians, and advocacy voices, with a strong focus on translational science, delivery platforms, regulatory evolution, and patient access. Conversations span aging biology, rare diseases, genome editing, CNS-directed gene therapy, vector design, manufacturing hurdles, and policy, often pairing scientific deep-dives with practical implications for developers, providers, and funders. A standout trait is the mix of highly technical discussions and founder/advocacy perspective, making it useful for listeners evaluating partnerships, sponsorships, and opportunities to connect with a deeply engaged community working at the cutting edge of life sciences and biotech policy.... more

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Which podcasts are similar to ASGCT Podcast Network?

These podcasts share a similar audience with ASGCT Podcast Network:

1. Cell & Gene: The Podcast
2. The Long Run with Luke Timmerman
3. BioCentury This Week
4. Ground Truths
5. The Readout Loud

How many episodes of ASGCT Podcast Network are there?

ASGCT Podcast Network launched 4 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on ASGCT Podcast Network?

Recent guests on ASGCT Podcast Network include:

1. Paloma Giangrande
2. Luigi Naldini
3. Jerry McLaughlin
4. Brannon Nicholls
5. Robert Carlisle
6. Bruce Levine
7. Nirali Shah
8. Sara Johnson Davis

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