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Artwork for AI + a16z

AI + a16z

a16z
Artificial Intelligence
Generative AI
AI Applications
Generative Models
Openllms
Nvidia
Mistral
Chatgpt
Multimodal Models
Openai
3D Models
Hiring Process
Cyber Security
Deep Learning
AGI
Machine Learning
Cybersecurity
Llama
Gpt-3
Large Language Models

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

PublishesTwice weeklyEpisodes91Founded2 years ago
Number of ListenersCategories
BusinessEntrepreneurshipTechnology

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Artwork for AI + a16z

Latest Episodes

Joe Schmidt speaks with Peter Doyle, CEO of Treeline, about why the $100B managed service provider market is a decade behind modern technology and how Treeline is building a new model that combines human technicians with AI and automation. They discu... more

Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with 15 years later, why he'd spen... more

Yoko Li, Guido Appenzeller, and Joel de la Garza discuss OpenClaw, the open source personal AI assistant that's forcing a rethink of how identity, permissions, and security work on the internet. They cover why setting up Gmail integration took seven ... more

Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predictions in a precise, mathematically predictable way as they process new information... more

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Recent Guests

Vishal Misra
Professor and Vice Dean of Computing and AI at Columbia University
Columbia University
Episode: What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Amjad Masad
CEO at Replit
Replit
Episode: Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI
Ankur Goyal
Founder and CEO of Braintrust, previously worked on AI-powered document extraction at Figma
Braintrust
Episode: Evals, Feedback Loops, and the Engineering That Makes AI Work
Martin Casado
General partner at Andreessen Horowitz responsible for their billion dollar infrastructure practice.
Andreessen Horowitz
Episode: Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
Hahn Wang
Co-founder of Mintlify
Mintlify
Episode: How Mintlify Is Rebuilding Documentation for Coding Agents
Hahnbee Lee
Co-founder of Mintlify
Mintlify
Episode: How Mintlify Is Rebuilding Documentation for Coding Agents
Simon Mo
Co-founder of Inferact and lead contributor on the VLLM open source project
Inferact
Episode: Inferact: Building the Infrastructure That Runs Modern AI
Woosuk Kwon
Co-founder of Inferact and lead contributor on the VLLM open source project
Inferact
Episode: Inferact: Building the Infrastructure That Runs Modern AI
Matt Knight
VP of Security Products and Research at OpenAI
OpenAI
Episode: The AI That Found A Bug In The World’s Most Audited Code

Host

Martin Casado
Co-host; General Partner at a16z; focuses on AI infrastructure and venture dynamics

Reviews

4.2 out of 5 stars from 90 ratings
  • The Best Guests

    IMHO the quality of a16z podcasts relies heavily on the guests. Being who they are, a16z gifts us with incredible guests and their wisdom. Thanks so much for being a beacon in the AI mist!

    Apple Podcasts
    5
    Roxtoxroxrox
    United States2 months ago
  • I love how it dives into the core of AI technology.

    Podchaser
    5
    thetravelinggreek
    2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Shows offer practical, battle-tested insights for builders and investors.
Open-source and engineering-first angles give unique value compared to other AI podcasts.
Guests are consistently high-caliber and deeply informed.
Content stays very relevant to AI infrastructure and VC trends.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#85
United States/Technology
Apple Podcasts
#54
United Kingdom/Technology
Apple Podcasts
#109
Canada/Technology
Apple Podcasts
#118
Australia/Technology
Apple Podcasts
#139
Germany/Technology
Apple Podcasts
#240
Italy/Technology

Talking Points

Recent interactions between the hosts and their guests.

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Q: How do you see the role of continual learning versus scaling in achieving AGI?
Scale alone won't solve everything; you need continual learning to preserve plasticity and a robust causal model to move from correlation to causation, which are essential to reach AGI.
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Q: What is the Bayesian wind tunnel and why was it needed?
The Bayesian wind tunnel is a controlled, memory-free testing environment where we give models a task impossible to memorize and analytically compute the Bayesian posterior, to prove that certain architectures perform true Bayesian updating.
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Q: Can you give a quick background on how you started investigating LLMs and what led to your first paper?
I moved from practical problem-solving with GPT-3 to building a mathematical model of how LLMs function, starting with a DSL for cricket stats and showing that the model's probabilities updated in a way that resembled Bayesian updating.
Sam Altman on Sora, Energy, and Building an AI Empire
Q: What are your thoughts on the future of energy in relation to AI?
AI and energy are converging; in the short term, natural gas will grow, while long-term solutions will include solar and nuclear.
Sam Altman on Sora, Energy, and Building an AI Empire
Q: What's your latest thinking on collaborative versus competing with other companies?
OpenAI has decided to make an aggressive infrastructure bet and will partner widely to support that strategy.

Audience Metrics

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Frequently Asked Questions About AI + a16z

What is AI + a16z about and what kind of topics does it cover?

A cutting-edge mix of venture-capital perspective, AI infrastructure, and developer-facing tooling, with conversations often centering on how AI changes capital markets, product engineering, and open-source ecosystems. Episodes frequently explore how infrastructure, open models, and scalable platforms shape startup value, funding dynamics, and enterprise adoption, while highlighting the people driving and funding these shifts. Noteworthy strengths include high-caliber guests from leading venture firms and AI startups, plus a clear focus on practical implications for builders, operators, and investors.

Listeners likely benefit from actionable insights on AI infrastructure, funding cycles, and how to position technology bets in rapidly evolv... more

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AI + a16z launched 2 years ago and published 91 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on AI + a16z?

Recent guests on AI + a16z include:

1. Vishal Misra
2. Amjad Masad
3. Ankur Goyal
4. Martin Casado
5. Hahn Wang
6. Hahnbee Lee
7. Simon Mo
8. Woosuk Kwon

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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