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The Tortured Proteins Department

Stephanie Wankowicz
National Institutes Of Health
NIH
Alphafold
Vanderbilt University
UCSF
Open Science
Protein Structure Prediction
Protein Dynamics
Machine Learning In Biology
Meta-Science
Protein Folding
Pubmed Central
Open Science / Preprints
Social Media In Science
Biophysical Society
Isomorphic Labs
AI In Grad Education
Graduate Science Education
NIH Funding
USDA

A deep dive into scientific discovery and the process of doing science, hosted by Stephanie Wankowicz and James Fraser.

PublishesMonthlyEpisodes15Foundeda year ago
Number of ListenersCategories
Life SciencesScience

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Artwork for The Tortured Proteins Department

Latest Episodes

We chat about the conformational ensembles conference, NIH-proposed policy changes, 4!! preprints, & running.

NIH news:

OMB Proposal

Blog Post Summary on OMB Proposal

RFI to Cap the Number of Simultaneous Research Project Grants

Early Indepen... more

NIH Strategic Plan Comments (Due 5/26)

Preprint:

Cooling fast and slow: Characterising the effects of vitrification in cryo-EM and the subsequent recovery of equilibrium populations

cryoAgent: An agentic workflow for robust and adaptive end-to-en... more

diffUSE Project

April Fools Blog

NIH News:

Funding Curve

Drug Monkey 2025 Grant Report

How the 2025 NIH grant terminations varied by researchers’ demographic groups

Preprints:

Intrinsic dataset features drive mutational effect prediction by ... more

Topics:

Olympics

NIH Bureaucracy - Grants & Leaderships

Preprints

12 episodes of TTPD!

Claude Code & Slack Apps

San Francisco Half

Preprints:

Bidirectional allosteric ligand regulation in a central glycolytic enzyme

Large-scale exploration... more

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Hosts

Stephanie Wankowicz
Host of The Tortured Proteins Department; frequently discussed as a leading voice with academic roles (Vanderbilt University) and involvement in open science and mentorship.
Jamie Fraser
Co-host frequently featured in discussions on drug discovery, structural biology, and policy-related science communication.
James Fraser
Host and Professor; regular contributor on bioscience topics, publishing culture, and policy in the life sciences.

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Frequently Asked Questions About The Tortured Proteins Department

What is The Tortured Proteins Department about and what kind of topics does it cover?

The show centers on the realities of doing science in modern times, with frequent deep dives into protein science, structural biology, and the evolving landscape of research culture. Episodes blend lab life, policy shifts, funding dynamics, and the growing role of AI and open science in everyday practice, often framed through conference travel, publishing trends, and mentoring experiences. Listeners likely include researchers and academics who want practical takes on preprints, funding, and responsible science communication, as well as science professionals navigating open data, automation, and interdisciplinary collaboration. A notable strength is the conversational, policy-aware angle that connects hands-on lab work to broader systemic ch... more

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Which podcasts are similar to The Tortured Proteins Department?

These podcasts share a similar audience with The Tortured Proteins Department:

1. The Long Run with Luke Timmerman
2. The Readout Loud
3. Nature Podcast
4. The Ezra Klein Show
5. The Daily

How many episodes of The Tortured Proteins Department are there?

The Tortured Proteins Department launched a year ago and published 15 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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