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The Pauling Principle

PAULING.AI

AI and drug discovery to extend healthy human lifespan. Sponsored by www.pauling.ai

PublishesTwice monthlyEpisodes19Founded9 months ago
Number of ListenersCategories
ScienceLife Sciences

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Latest Episodes

Is protein folding solved? Not quite, even though the progress has been tremendous since the first AlphaFold and up to last year's Nobel prize. The team behind Boltz and Boltz-2, from MIT CSAIL and Jameel Clinic, just released Boltzgen, a state of th... more

Shantanu Singh is one of the principal investigators at the celebrated Broad Institute of MIT and Harvard. His research is centered around finding “fingerprints” of genes, chemicals and diseases from microscopy images of cells. Which has tremendous a... more

Andy and his team at Vincere have been doing amazing work over years to figure out the mitochondrial mechanisms that may contribute to Parkinson's and other neurodegenerative diseases. Listen in as we discuss curing Parkinson's, using AI to find new ... more

Andrew White and his team at Future House have one of the most ambitious missions. I'll quote here because I couldn't say it better myself: Our mission is to build an AI scientist, or AI systems, that can automate scientific research and accelerate t... more

What if the biggest breakthroughs in health and biotechnology aren’t waiting on new ideas but on better experiments? In this episode, Michael Florea joins Javier to expose the hidden bottlenecks in animal research, the quiet revolution of automation ... more

Join my conversation with Matthew "Oki" O'Connor Co-CEO of Cyclarity Therapeutics. We talk about curing cardiovascular disease, radically extending healthy longevity and the drug discovery journey.

Nicholas Runcie of Oxford University and I discuss whether large language models such as ChatGPT can really understand chemistry. Which of course will be essential as we try to use them to find new medicines and materials.

Eva Smorodina, researcher at the University of Oslo and expert in Computational Chemistry, joins me for an interesting conversation about designing antibodies, tools for biology and the future of AI and drug discovery. I hope you will enjoy!

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The Pauling Principle launched 9 months ago and published 19 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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